Orbital alveolar soft-part sarcoma: clinico-pathological profiles, management and outcomes.

Abstract:

AIM:To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). MATERIALS AND METHODS:We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. RESULTS:Age at presentation varied from 1 to 31 years. Both, children and adults were affected. Proptosis was the most common clinical presentation. PAS-positive diastase-resistant crystals and granules were found in all cases. All patients received adjuvant radiotherapy. Two cases had positive surgical margins and were treated with additional adjuvant chemotherapy. None of the patients had recurrence or metastases till the last follow up. CONCLUSION:Early diagnosis with a multidisciplinary, multimodal approach of treatment is quintessential in achieving a long disease-free survival in patients with ASPS.

journal_name

J Cancer Res Ther

authors

Mulay K,Ali MJ,Honavar SG,Reddy VA

doi

10.4103/0973-1482.136570

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

294-8

issue

2

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2014_10_2_294_136570

journal_volume

10

pub_type

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