Abstract:
OBJECTIVE:The purpose of this meta-analysis was to evaluate the predictive value of cervical lymph node metastasis through sentinel lymph node biopsy (SLNB) in patients with oral cancer. MATERIALS AND METHODS:Two authors independently searched the databases of PubMed, Cochrane central register of controlled trials, EMBASE, and CNKI to find the potential suitable diagnostic study related to SLNB. The diagnostic sensitivity, specificity, positive likely hood ratio (+LR), negative likely hood ratio (-LR), diagnostic odds ratio (DOR) were pooled by Meta-DiSc1.4 software. The publication bias was assessed by funnel plot and line regression test. RESULTS:After electronic searching the related databases, we finally included twenty diagnostic studies. The pooled sensitivity, specificity, +LR, and DOR were 0.91 (95% confidence interval [CI]: 0.88-0.94), 1.00 (95% CI: 0.99-1.00), 35.52 (95% CI: 19.19-65.75), and 323.50 (95% CI: 148.27-705.83), respectively, with fixed-effect model. Moreover, the pooled -LR was 0.13 (95% CI: 0.07-0.23) by random-effect model. The area under the summary receiver operating characteristic curve of SLNB for cervical lymph node metastasis was 0.99. CONCLUSION:SLNB had very high sensitivity and specificity for productizing cervical lymph node metastasis in oral cancer patients.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Lin R,Yan J,Liu W,Fan T,Tang Ldoi
10.4103/0973-1482.200751subject
Has Abstractpub_date
2016-12-01 00:00:00pages
C256-C259issue
Supplementeissn
0973-1482issn
1998-4138pii
JCanResTher_2016_12_8_256_200751journal_volume
12pub_type
杂志文章,meta分析abstract::Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/jcrt.JCRT_729_18
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous microwave ablation (MWA) in the treatment of advanced hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Three thousand cases of advanced HCC patients were randomly divided into two groups: 15...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.200598
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the value of two quantitative indicators, the apparent diffusion coefficient (ADC) and the exponent apparent diffusion coefficient (EADC), of magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in the differential diagnosis of ovarian epithelial tumors. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.163667
更新日期:2016-01-01 00:00:00
abstract::Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/jcrt.JCRT_212_17
更新日期:2019-01-01 00:00:00
abstract:Purpose:The purpose of the study is to retrospectively evaluate the safety and efficacy of microwave ablation (MWA) for the treatment of ground-glass opacity (GGO)-lung adenocarcinoma. Materials and Methods:From December 2013 to June 2017, a total of 51 patients (22 males and 29 females, mean age of 69.4 ± 10.1 years)...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_269_18
更新日期:2018-01-01 00:00:00
abstract::The present case report defines a rare case of a liposarcoma with bone metastasis resulting in a complete remission (CR) following trabectedin treatment. The patient was referred with abdominal swelling and pain. A retroperitoneal mass was detected and described as dedifferentiated liposarcoma (DDLS). The mass was sur...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
doi:10.4103/0973-1482.158032
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To explore the outcome and prognostic factors of recursive partitioning analysis (RPA) Class III brain metastatic patients treated with stereotactic radiotherapy (SRT). MATERIALS AND METHODS:Fifty-six consecutive patients with metastatic brain tumors and Karnofsky performance scale (KPS) scores <70 treated w...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.160925
更新日期:2016-01-01 00:00:00
abstract:Objective:This study presents a method to estimate midplane dose (Diso, transit) in vivo from transit signal (St) measured with thimble ionization chamber in cancer of the middle-third esophagus patients treated with three-dimensional radiotherapy (RT). This detector is positioned at the level of electronic portal imag...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_278_17
更新日期:2018-01-01 00:00:00
abstract::Burkitt's lymphoma is an uncommon form of non-Hodgkin's lymphoma (NHL) in adults and represents < 5% of NHL adults. Burkitt's lymphoma involving primarily the appendicular skeleton is rarely described. We present the case of a young man with primary Burkitt's lymphoma involving the humerus as the only site of disease....
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.148678
更新日期:2015-10-01 00:00:00
abstract::Dermatofibrosarcoma protuberans (DFSP) is a low-grade tumor with rare metastasis. A 26-year-old male presented with multiple cutaneous nodular lesions of DFSP since 3 months along with distant metastasis to the brain, pleura, and muscles that were detected on investigations. The case is being reported due to its rare ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.146099
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:The oncogenic form of anaplastic lymphoma kinase (ALK) gene is an attractive candidate marker for diagnostic and therapeutic purposes in several malignancies, including nonsmall cell lung cancer (NSCLC). This study aimed to examine the expression levels and clinical significance of ALK in a series of NSCLC...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.170940
更新日期:2016-04-01 00:00:00
abstract::Placement of long term central venous access devices (CVAD) such as chemo ports and Hickman's catheters are associated with a definite risk of catheter tip malpositioning. As such, malpositioning runs a risk of venous thrombosis and related complications; it is imperative to reposition the catheter. Percutaneous trans...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.63554
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this meta-analysis was to evaluate the effects of Fufangkushen injection combined with chemotherapy in the treatment of stomach cancer. MATERIALS AND METHODS:The relevant clinical trials about Fufangkushen injection combined with chemotherapy in the treatment of stomach cancer were search in t...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
doi:10.4103/0973-1482.139755
更新日期:2014-08-01 00:00:00
abstract:Introduction:Oxaliplatin-induced neurotoxicity is the single main dose-limiting factor in the treatment of colorectal cancer. The degree of neurotoxicity may be either acute and reversible or observed as cumulative and chronic peripheral nerve damage leading to peripheral neuropathy (PNP), walking difficulties, extremi...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_971_16
更新日期:2018-07-01 00:00:00
abstract:Aims:To find the spectrum and frequency of lower gastrointestinal malignancies and diagnostic accuracy of colonoscopic brush cytology in their diagnosis. Materials and Methods:This was a prospective study carried out on 49 patients in the Department of Pathology over 1 year. Brushing material was smeared directly onto...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.176416
更新日期:2018-04-01 00:00:00
abstract::Carcinoma of the lip is a slow-growing locally-advanced disease with low metastatic potential. Distant skeletal metastasis is reported very rarely and the vertebral column is the most common site. A 58-year-old male smoker presented with pain and massive swelling of the left scapula for six months. He also noticed a s...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.73338
更新日期:2010-07-01 00:00:00
abstract:Context:Familial adenomatous polyposis (FAP) is an autosomal dominant disorder. Colorectal cancer (CRC) has been implicated as the most common cause of death in FAP patients, especially in those with coexisting CRC at initial diagnosis (FAP-CRC). Aim:We aimed to determine the survival rate of FAP-CRC and the factors a...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_421_17
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To assess the efficacy of radiation in the treatment of juvenile nasopharyngeal angiofibroma (JNA). MATERIALS AND METHODS:Data were retrieved for JNA treated with radiotherapy from 1987-2012. The demographics, treatment and outcome data were recorded in predesigned proforma. RESULTS:Data of 32 patients were r...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.150349
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The aim of this retrospective study was to evaluate the clinical efficacy and prognosis of breast-conserving surgery versus modified radical mastectomy in the treatment of early stage breast cancer. PATIENTS AND METHODS:Two hundred and nineteen cases of early stage breast cancer were reviewed and retrospecti...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.163835
更新日期:2015-08-01 00:00:00
abstract::Medullary thyroid carcinoma is a rare thyroid neoplasm that can be either sporadic or familial. It occurs in adults, presenting as a solitary cold nodule on thyroid scan. Most are solid, firm, and non-encapsulated, and occur in the mid portion or upper half of the thyroid gland, corresponding to areas with greater num...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.82916
更新日期:2011-04-01 00:00:00
abstract:Background:Initiation, promotion, progression, and metastasis of mammary tumors are mediated by dysregulation of multiple genes involved in various signaling pathways. Expressional variation of these molecules significantly influences cancer cell proliferation in breast cancer. Aims and Objectives:In the current study...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_484_18
更新日期:2020-10-01 00:00:00
abstract:Background:Nuclear factor kappa B (NFkB-light-chain-enhancer of activated B-cells) expression and its regulation is a key role in the development of number of malignancies, as NFkB mediates the balance between cell death and its survival. Therefore, NFkB regulation constitutes an attractive target to overcome the resis...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_348_18
更新日期:2018-12-01 00:00:00
abstract::Large pedunculated esophageal lipoma is uncommon. The presenting symptoms of esophageal lipoma are dysphagia, regurgitated mass, and persistent sensation of a lump in the throat. The most frequent location of the tumor pedicle is the upper esophageal sphincter. Here, we present the case of a 52-year-old man who had th...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
doi:10.4103/0973-1482.154089
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the expression of Twist, E-cadherin, and N-cadherin both in normal endometrium and in endometrioid adenocarcinoma tissues (NET and EAT), and further discuss the relationship between the proteins expression and the clinical parameters. METHODS:Seventy-six EAT and 50 NET...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_405_17
更新日期:2017-01-01 00:00:00
abstract::Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_450_17
更新日期:2020-07-01 00:00:00
abstract::Interstitial permanent radioactive seed implantation delivers a high local dose to tumors and sharply drops off at surrounding normal tissues. Radioactive seeds implanted via ultrasound or computed tomography (CT) guidance are minimally invasive and facilitate quick recovery. Transrectal ultrasound-guided 125I seed im...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/jcrt.JCRT_434_19
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Cancer, a disorder of cellular behavior is characterized by the alteration of serum glycoproteins, which are composed of different monosaccharides. One of the monosaccharides is l-fucose, a methyl pentose, which is the terminal sugar in most of the plasma glycoproteins. Elevated levels of protein-bound fucos...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.82928
更新日期:2011-04-01 00:00:00
abstract::Pituitary adenoma is one of the most common intracranial neoplasms, usually presenting with endocrinopathies or visual field defects. Granulomatous hypophysitis, one of the subtypes of primary hypophysitis, is a rare neurological entity presenting as a sellar lesion with mass effect symptoms and endocrinological dysfu...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/jcrt.JCRT_677_16
更新日期:2017-07-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 已发布勘误
doi:10.4103/0973-1482.197539
更新日期:2016-07-01 00:00:00
abstract::Most neuroendocrine tumors of the gastrointestinal tract are traditionally termed "carcinoid tumors." More than 90% of all gastrointestinal carcinoids are located in the appendix, small intestine, rectum, and mesenteric carcinoids are rare. Even when invasive, most carcinoids are relatively indolent and display minima...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
doi:10.4103/0973-1482.138108
更新日期:2015-07-01 00:00:00