Clinical study of transcatheter arterial chemoembolization combined with microwave ablation in the treatment of advanced hepatocellular carcinoma.

Abstract:

OBJECTIVE:To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous microwave ablation (MWA) in the treatment of advanced hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Three thousand cases of advanced HCC patients were randomly divided into two groups: 1500 cases in the treatment group were treated with TACE combined with MWA and 1500 cases in the control group were treated with TACE. RESULTS:The effective rate of the treatment group and control group was 71.4% and 42.8%, respectively, and the difference between the two groups was statistically significant (P < 0.05). During the follow-up period at 6, 12, 18, and 24 months postoperatively, the survival rates of the treatment group were 88.1%, 73.8%, 52.3%, and 33.3%, and the survival rates of the control group were 76.2%, 57.1%, 30.9%, and 9.5%, respectively. There was no significant difference in postoperative complications between the two groups. CONCLUSION:It is safe and effective to use TACE combined with MWA in the treatment of advanced HCC, and the effect of combined treatment is better than that of TACE alone.

journal_name

J Cancer Res Ther

authors

Li W,Man W,Guo H,Yang P

doi

10.4103/0973-1482.200598

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

C217-C220

issue

Supplement

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2016_12_7_217_200598

journal_volume

12

pub_type

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