Abstract:
BACKGROUND:Cancer, a disorder of cellular behavior is characterized by the alteration of serum glycoproteins, which are composed of different monosaccharides. One of the monosaccharides is l-fucose, a methyl pentose, which is the terminal sugar in most of the plasma glycoproteins. Elevated levels of protein-bound fucose have been reported in various disease states as well as in malignancies. AIM:To ascertain the role of serum fucose as a biomarker and to correlate with other studies for its effective clinical application. MATERIALS AND METHOD:T0 he study was carried out on 67 subjects, including 14 healthy individuals and 53 oral squamous cell carcinoma cases. The serum fucose level estimation was done based on the method as adopted by Winzler using cysteine reagent. Statistical analysis included Chi-square test, Karl Pearson correlation test and Student's t test to evaluate the significance and variability of values between groups. RESULTS:Serum fucose levels were independent of age and sex. However, there was significant increase in mean serum fucose level of oral squamous cell carcinoma patients compared with healthy controls. The results correlated well with other studies. CONCLUSION:Serum fucose can be used as an effective diagnostic biomarker in oral squamous cell carcinoma patients.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Parwani RN,Parwani SRdoi
10.4103/0973-1482.82928subject
Has Abstractpub_date
2011-04-01 00:00:00pages
143-7issue
2eissn
0973-1482issn
1998-4138pii
JCanResTher_2011_7_2_143_82928journal_volume
7pub_type
杂志文章abstract::Intra-nodal palisaded myofibroblastoma (IPM) is a rare benign lymph node mesenchymal tumor. It presents as a slow growing, painless nodular mass confined mostly to the inguinal area. Histologically, it shows palisading spindle cells, hemorrhages, hemosiderin laden macrophages, and amianthoid fibers, almost totally rep...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.113395
更新日期:2013-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2015-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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doi:10.4103/0973-1482.204898
更新日期:2018-12-01 00:00:00
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更新日期:2015-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 信件
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2006-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.137993
更新日期:2014-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_736_19
更新日期:2020-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.113379
更新日期:2013-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.73339
更新日期:2010-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.183181
更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.73367
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_930_17
更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.40825
更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章,评审
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