The diagnostic accuracy of colonoscopic brush cytology in diagnosis of colorectal malignancies: A study of 49 patients.

Abstract:

Aims:To find the spectrum and frequency of lower gastrointestinal malignancies and diagnostic accuracy of colonoscopic brush cytology in their diagnosis. Materials and Methods:This was a prospective study carried out on 49 patients in the Department of Pathology over 1 year. Brushing material was smeared directly onto at least two clean glass slides. The air dried smears were stained with May Grunwald Giemsa stain. The endoscopic biopsies were examined grossly and were fixed in 10% formalin, processed and stained with Hematoxylin and Eosin stain, respectively. Special stains were used wherever required. Observation and Results:The study was done on 49 patients presented with colorectal and anal lesions. Age of the patients ranged from 17 to 72 years with male to female ratio being 1.57:1. On statistical analysis, the sensitivity of colonoscopic brush cytology was found to be 85.71% and specificity 61.53%. The accuracy came out to be 79.16%. Conclusion:Brush cytology is a reliable, safe, inexpensive, and rapid method of diagnosing gastrointestinal lesions. Since brushing is a relatively noninvasive procedure, routine use of brushings of colonoscopically visible lesions should be done, in addition, to biopsy to increase the diagnostic yield.

journal_name

J Cancer Res Ther

authors

Kaur S,Sharma R,Kaushal V,Gulati A,Sharma B

doi

10.4103/0973-1482.176416

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

574-577

issue

3

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2018_14_3_574_176416

journal_volume

14

pub_type

杂志文章
  • Primary amyloidosis with high grade transitional cell carcinoma of bladder: a rare case report.

    abstract::Primary amyloidosis of bladder is a rare disease that closely resembles bladder cancer on clinical presentation with painless gross hematuria. Pathologically this is a totally benign non-neoplastic lesion and its association with urothelial carcinoma of the bladder is rare. We herein report a 64-year-old diabetic male...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.98994

    authors: Gupta P,Hanamshetti S,Kulkarni JN

    更新日期:2012-04-01 00:00:00

  • Systemic lupus erythematous increased lung cancer risk: Evidence from a meta-analysis.

    abstract:AIMS:Several studies suggested that systemic lupus erythematosus (SLE) were associated with the risk of lung cancer. However, other studies did not confirm the result. Therefore, we conducted a meta-analysis to investigate this association. MATERIALS AND METHODS:A systematic literature search was conducted using the P...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,meta分析

    doi:10.4103/0973-1482.172115

    authors: Wu Y,Hou Q

    更新日期:2016-04-01 00:00:00

  • Solitary fibrous tumor of the orbit: Computed tomography and histopathological findings.

    abstract::A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/jcrt.JCRT_1194_16

    authors: Sayit AT,Elmali M,Gul A,Sullu Y

    更新日期:2019-07-01 00:00:00

  • Plasma interleukin 17 in the diagnosis of hepatocellular carcinoma: a retrospective study of 39 cases.

    abstract:OBJECTIVE:The purpose of this retrospective study was to evaluate the diagnosis efficacy of plasma interleukin 17 (IL-17) for hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Thirty-nine patients with confirmed HCC and 41 healthy controls were retrospectively analyzed in this study. The serum level of IL-17 was t...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.151537

    authors: Liu J,Zhou G,Lu W

    更新日期:2014-12-01 00:00:00

  • Effect of gemcitabine on the uptake of (18)F-fluorodeoxyglucose and (18)F-fluorothymidine in lung adenocarcinoma A549 cells and the animal tumor model.

    abstract:BACKGROUND:Gemcitabine is the first-line drug for nonsmall cell lung cancer, and 18F-fluorodeoxyglucose. (18F-FDG) and 18F-fluorothymidine. (18F-FLT) are positron emission tomography. (PET) imaging agents. The aim of this study was to explore the effect of gemcitabine on the uptake of 18F-FDG and 18F-FLT in A549 cells ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.147713

    authors: Zhang B,Deng SM,Guo LC,Dong JJ,Zhu YB,Gao Y,Wang ZX,Cho WC

    更新日期:2016-01-01 00:00:00

  • Management of the neck in early oral cancers: Is the verdict out?

    abstract::The management of patients with the clinically negative neck (N0) in early oral cancers awaits a clear mandate despite growing evidence favoring elective neck dissection. Having a general policy of operating all N0 neck may indeed increase the number of unnecessary neck dissection in the true pathological N0 necks, a ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.164705

    authors: Rao VU,Patil PH,Rajaram BV

    更新日期:2016-07-01 00:00:00

  • Serum paraoxonase and arylesterase can be useful markers to predict neoadjuvant chemotherapy requirement in patients with breast cancer.

    abstract:Aim:The aims of this study are to evaluate the serum levels of paraoxonase (PON) and arylesterase (ARE) in breast cancer (BC) patients; to determine their relationship with chemotherapy requirements in BC; and to find a cut-off value to assess subjects with a higher risk of BC. Subjects and Methods:A total of 40 BC pa...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.235355

    authors: Okuturlar Y,Gunaldi M,Kocoglu H,Hursitoglu M,Gedikbasi A,Acarer D,Harmankaya O,Kumbasar A

    更新日期:2018-06-01 00:00:00

  • Mesothelioma with superior vena cava obstruction in young female following short latency of asbestos exposure.

    abstract::An 18 years female was admitted with right-sided chest pain, dry cough, and low-grade fever and weight loss for last 1 month. On examination, patient had features of superior vena cava (SVC) syndrome with right-sided pleural effusion. Chest X-ray showed mediastinal widening with nonhomogenous opacity mainly in the per...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.160924

    authors: Patra A,Kundu S,Pal A,Saha S

    更新日期:2015-10-01 00:00:00

  • Analysis of imaging-guided thermal ablation puncture routes for tumors of the hepatic caudate lobe.

    abstract:Aims:The goal of this study was to analyze the puncture routes of imaging-guided thermal ablation for tumors of the hepatic caudate lobe. Materials and Methods:The imaging-guided thermal ablation puncture routes of 12 cases of hepatic caudate lobe tumors were collected in our hospital from January 2013 to February 201...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_341_19

    authors: Yan Y,Lin ZY,Chen J

    更新日期:2020-01-01 00:00:00

  • Asthma and the risk of prostate cancer.

    abstract:Objective:The association between asthma and the risk of prostate cancer remains elusive. We aimed to evaluate the relationship between asthma and the onset of prostate cancer. Methods:We searched PubMed, Embase, and Cochrane databases for articles that assessed the association of asthma with the risk of prostate canc...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,meta分析

    doi:10.4103/0973-1482.176422

    authors: Li W,Mao S,Tu M,Ge X,Li K,Xie F,Song Y,Miao Y

    更新日期:2018-09-01 00:00:00

  • Evaluation of the organs at risk doses for lung tumors in gated and conventional radiotherapy.

    abstract:Purpose:The purpose of this study was to evaluate the organs at risk (OARs) doses for lung tumors in gated radiotherapy (RT) compared to conventional RT using the four-dimensional extended cardiac-torso (4D-XCAT) digital phantom in a simulation study. Materials and Methods:4D-XCAT digital phantom was used to create 32...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_735_18

    authors: Shahzadeh S,Gholami S,Aghamiri SMR,Mahani H,Nabavi M

    更新日期:2020-07-01 00:00:00

  • A case of invasive papillary breast carcinoma: Fierce façade with favorable prognosis.

    abstract::Invasive papillary carcinoma of the breast is a rare, distinct variant comprising approximately less than 1-2% of all newly diagnosed cases of breast carcinoma and is usually found in postmenopausal women with a more favorable prognosis. We report an unusual case in a 45-year-old perimenopausal female who came with a ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.154086

    authors: Vani D,Geetanjali S,Punja GM,Bharathi M

    更新日期:2015-10-01 00:00:00

  • MRI diagnosis of intradural extramedullary tumors.

    abstract:OBJECTIVE:This study evaluates the magnetic resonance imaging (MRI) manifestation of intradural extramedullary (IDEM) tumors to improve the imaging diagnostic level. MATERIALS AND METHODS:From January 2005 to December 2012, a retrospective analysis of the MRI examination was performed on 108 patients with IDEM tumors ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.137993

    authors: Gu R,Liu JB,Zhang Q,Liu GY,Zhu QS

    更新日期:2014-10-01 00:00:00

  • Low titer of antibody against Toxoplasma gondii may be related to resistant to cancer.

    abstract:CONTEXT:Toxoplasma gondii is a protozoan parasite with a world-wide distribution. However, the majority of infected cases remain symptomless. There are raising scientific evidences indicating that parasitic infections induce antitumor activity against certain types of cancers. The inhibitory effect of T. gondii on canc...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.144638

    authors: Seyedeh MS,Nahid S,Nahid M,Shima DP,Morteza Y,Hossein YD

    更新日期:2015-04-01 00:00:00

  • Identification of significant ego networks and pathways in rheumatoid arthritis.

    abstract:Objective:The objective of this paper is to identify ego networks and pathways in rheumatoid arthritis (RA) based on EgoNet algorithm and pathway enrichment analysis. Materials and Methods:The ego networks were identified based on the EgoNet algorithm which was comprised four steps: inputting gene expression data and ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.189250

    authors: Zhou WZ,Miao LG,Yuan H

    更新日期:2018-12-01 00:00:00

  • Huge primary mediastinal synovial sarcoma fully occupying the right hemithorax.

    abstract::Primary mediastinal synovial sarcomas are exceedingly uncommon tumors. Herein, we present the case of primary mediastinal synovial sarcoma (monophasic spindle cell-shaped variant) fully occupying the right hemithorax in a 37-year-old woman who presented to clinic with a 2-month history of right-sided chest pain and sh...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.172137

    authors: Abu-Zaid A,AlNajjar A,Alotaibi S,Alshawaf R,Alqeshtaini N,Alhaidar R,Mohammed S,AlKattan K

    更新日期:2018-04-01 00:00:00

  • Baicalein suppresses the proliferation of human cervical cancer cells via Notch 1/Hes signaling pathway.

    abstract:Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.204899

    authors: Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

    更新日期:2019-10-01 00:00:00

  • Definitive chemoradiotherapy in Stage III nonsmall cell lung cancer: Turkey experience.

    abstract:AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.163682

    authors: Yilmaz U,Yılmaz U,Yasar Z,Kıraklı EK,Ulger S,Ozdogan Y,Demirci NY,Erol S,Ozdogan I,Sahin B,Koksal D,Akcay C

    更新日期:2016-01-01 00:00:00

  • Clinical study on thalidomide combined with cinobufagin to treat lung cancer cachexia.

    abstract:Objective:To discuss and assess the clinical value of treating lung cancer cachexia with thalidomide combined with cinobufagin.s. Methods:A cohort of 54 patients, who were diagnosed with lung carcinoma, was randomly divided into two groups, a trial group and a control group, respectively. The trial group was given 150...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.188436

    authors: Xie M,Chen X,Qin S,Bao Y,Bu K,Lu Y

    更新日期:2018-01-01 00:00:00

  • Erratum: Primary large cell neuroendocrine carcinoma of the prostate in a hormone naive patient: A case report from Taiwan.

    abstract::[This corrects the article DOI: 10.4103/0973-1482.180685]. ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 已发布勘误

    doi:10.4103/0973-1482.274082

    authors:

    更新日期:2019-10-01 00:00:00

  • Comparison of beam hardening effect of physical and enhanced dynamic wedges at bladder inhomogeneity using EBT3 film dosimeter.

    abstract:INTRODUCTION:Using physical wedges (PWs) to modify dose distribution and more homogeneous target coverage is a well-established technique. However, there are many problems with PWs known as beam hardening, which made them problematic. This can be overcome by dynamic wedges which do not filter beam. Comparison of physic...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.206244

    authors: Geraily G,Sharafi N,Shirazi A,Esfehani M,Masoudifar M,Rajab BE

    更新日期:2017-01-01 00:00:00

  • Hypercalcemia and treated breast cancers: the diagnostic dilemma.

    abstract::The relationship of hypercalcemia with cancer is well described in the literature. Breast cancer is the commonest malignancy associated with hypercalcemia; the detection of hypercalcemia in these patients usually signifies metastatic disease and is associated with a poor prognosis. However, the treating oncologist sho...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.48770

    authors: Rao V,Chaukar D,D'Cruz AK

    更新日期:2009-01-01 00:00:00

  • Unusual clinical and radiological presentation of metastatic choriocarcinoma to the brain and long-term remission following emergency craniotomy and adjuvant EMA-CO chemotherapy.

    abstract::Choriocarcinoma is the most malignant tumor of gestational trophoblast origin. Metastasis to brain is considered a poor prognostic indicator. Recent advances in adjuvant radiotherapy and chemotherapy have led to an excellent outcome of these patients. Craniotomy is indicated in selected cases with cerebral metastases....

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.77069

    authors: Dadlani R,Furtado SV,Ghosal N,Prasanna KV,Hegde AS

    更新日期:2010-10-01 00:00:00

  • Transnasal endoscopic resection of vascular leiomyomas of the nasal septum.

    abstract:OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.150417

    authors: Chen HH,Wang QY,Zhou SH

    更新日期:2016-01-01 00:00:00

  • Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer.

    abstract:BACKGROUND:Tumor markers are a major part of the secondary prevention and thus the detection of malignancies. Neoplasms often have an increased concentration of sialic acid on the tumor cell surface and are shed or secreted by some of these cells which increase the concentration in blood. MATERIALS AND METHODS:The stu...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73339

    authors: Joshi M,Patil R

    更新日期:2010-07-01 00:00:00

  • Primary papillary thyroid carcinoma previously treated incompletely with radiofrequency ablation.

    abstract::Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73328

    authors: Kim HY,Ryu WS,Woo SU,Son GS,Lee ES,Lee JB,Bae JW

    更新日期:2010-07-01 00:00:00

  • Lambda light chain myeloma presenting as nodular hepatic lesion: a clinical rarity.

    abstract::We report a case of a 63-year-old lady presenting with pain in the right hypochondrium, jaundice, anorexia, and firm tender hepatomegaly with remarkably high serum alkaline phosphatase. Abdominal ultrasonography revealed a hypoechoic solid space-occupying lesion in right lobe of liver which was cytologically diagnosed...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.131409

    authors: Pal S,Chattopadhyay B,Chatterjee A,Bhattacharya B

    更新日期:2014-01-01 00:00:00

  • Identification of activated pathways in lung adenocarcinoma based on network strategy.

    abstract:Background:Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Materials and Methods:Kyoto E...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.199458

    authors: Yu B,Li T,Chen J,Wang FQ,Fu JH,Liu SM,Wang Y,Zhang X,Yang HT

    更新日期:2020-07-01 00:00:00

  • Spritzer: For diagnostic cytopathology.

    abstract:BACKGROUND:Exfoliative cytology is an easy, economical, noninvasive, and feasible method for early detection and screening program of any premalignant or malignant lesion. In case of routine cytological procedure, classical Papanicolaou (PAP) stain is widely used while Romanowsky stains are sparingly used. Leishman-Gie...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.174548

    authors: Metgud R,Surbhi.,Naik S,Patel S

    更新日期:2017-10-01 00:00:00

  • Radiotherapy for management of skin cancers in fibrodysplasia ossificans progressiva: a case report and review of the literature.

    abstract::Fibrodysplasia ossificans progressiva (FOP) is a rare condition of ectopic calcification leading to increasing disability throughout life, with most patients being wheelchair bound by the age of 30. Ectopic calcification can be triggered by trauma and it is therefore important to minimize biopsies and operative proced...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.39603

    authors: Frew JA,Kelly CG

    更新日期:2008-01-01 00:00:00