Application of apparent diffusion coefficient and exponent apparent diffusion coefficient values in magnetic resonance imaging diffusion-weighted imaging to differentiate benign and malignant ovarian epithelial tumors.

Abstract:

OBJECTIVE:The aim of this study was to investigate the value of two quantitative indicators, the apparent diffusion coefficient (ADC) and the exponent apparent diffusion coefficient (EADC), of magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in the differential diagnosis of ovarian epithelial tumors. MATERIALS AND METHODS:Clinical and MRI data from ovarian epithelial tumors were analyzed after pathology confirmation of 85 lesions from 76 cases (47 lesions from 41 benign cases; 38 lesions from 35 malignant cases). Patients underwent routine MRI examination and DWI before surgery. The average ADC and EADC values of the solid sections of the tumors were measured when the b value was 1000 s/mm 2. RESULTS:The mean ADC value of the solid sections in the benign group was 1.28 ± 0.23 × 10-3 mm 2/s; the average EADC value was 27.96 ± 5.78 × 10-2. In the malignant group, the mean ADC value of the solid sections was 0.86 ± 0.17 × 10-3 mm 2/s; the average EADC value was 42.37 ± 5.96 × 10-2. When the b value was 1000 s/mm 2, there was a statistically significant difference in ADC and EADC values between benign and malignant ovarian tumors (P < 0.05). CONCLUSION:ADC and EADC values of DWI can be used to differentiate benign and malignant ovarian epithelial tumors.

journal_name

J Cancer Res Ther

authors

Wang YX,Yuan MZ,Wen ZX

doi

10.4103/0973-1482.163667

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

401-5

issue

1

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2016_12_1_401_163667

journal_volume

12

pub_type

杂志文章
  • The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate

    abstract:CONTEXT:The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1), which has been isolated from dried Antrodi...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.106529

    authors: Wei PL,Tu SH,Lien HM,Chen LC,Chen CS,Wu CH,Huang CS,Chang HW,Chang CH,Tseng H,Ho YS

    更新日期:2012-10-01 00:00:00

  • Cytology of hyalinising trabecular adenoma-like variant of medullary thyroid carcinoma.

    abstract::Medullary thyroid carcinoma is a rare thyroid neoplasm that can be either sporadic or familial. It occurs in adults, presenting as a solitary cold nodule on thyroid scan. Most are solid, firm, and non-encapsulated, and occur in the mid portion or upper half of the thyroid gland, corresponding to areas with greater num...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.82916

    authors: Santosh KV,Raychaudhuri S,Subramanya H,Naveen Kumar BJ

    更新日期:2011-04-01 00:00:00

  • Impact of Toombak dipping in the etiology of oral cancer: gender-exclusive hazard in the Sudan.

    abstract:BACKGROUND:Oral cancer (OC) mortality is very high in Sudan, particularly among men due to the habit of Toombak use (tobacco specific nitrose amine (TSN)) rich tobacco. AIMS:Our aim was to determine whether OC is gender-specific due to increased Toombak use among males as suggested a risk for subsequent development of...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.34696

    authors: Ahmed HG,Mahgoob RM

    更新日期:2007-04-01 00:00:00

  • Erratum: Herceptin as a single agent in the treatment of patients with metastatic breast cancer.

    abstract::[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 已发布勘误

    doi:10.4103/0973-1482.197539

    authors:

    更新日期:2016-07-01 00:00:00

  • Survival and failure patterns in atypical and anaplastic meningiomas: A single-center experience of surgery and postoperative radiotherapy.

    abstract:INTRODUCTION:Intracranial meningiomas are the second most common tumor of the CNS. The high-grade tumors are atypical and malignant meningioma comprising 5-7% and 1-3% of all meningiomas. The high-grade meningioma have an aggressive histopathological and clinical behavior. MATERIALS AND METHODS:We retrospectively revi...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 临床试验,杂志文章

    doi:10.4103/0973-1482.151426

    authors: Kumar N,Kumar R,Khosla D,Salunke PS,Gupta SK,Radotra BD

    更新日期:2015-10-01 00:00:00

  • Association between clinical pathology and multiple genes mRNA expression in Chinese patients with NSCLC.

    abstract:OBJECTIVE:The aim of this study was to evaluate whether there was an association between pathology type and ERCC1, BRCA1, RRM1, TUBB3, STMN1, TOP2A and epidermal growth factor receptor (EGFR) messenger ribonucleic acid (mRNA) expression level in Chinese patients with non-small cell lung carcinoma (NSCLC). MATERIALS AN...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.119118

    authors: Chen G,Jundong GU,Chen J,Liu Y,Song Z

    更新日期:2013-09-01 00:00:00

  • Adding bit of esthetics with science modification of batwing mastopexy for breast conservation in a young patient with giant fibroadenoma breast.

    abstract::A 19-year-old girl presented with a lump in her right breast and with a history of surgery for the similar complaint 3 years back. Ultrasound was suggestive of benign solitary lesion of size 16 cm × 10 cm. Core biopsy was suggestive of phyllodes tumor, and the histopathology report of previous surgery was also suggest...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/jcrt.JCRT_818_17

    authors: Kumar HH,Rahman NKF,Ramesh RS,Raghunandan GC

    更新日期:2019-07-01 00:00:00

  • Conformal radiotherapy for locally advanced juvenile nasopharyngeal angio-fibroma.

    abstract:PURPOSE:To assess the efficacy of radiation in the treatment of juvenile nasopharyngeal angiofibroma (JNA). MATERIALS AND METHODS:Data were retrieved for JNA treated with radiotherapy from 1987-2012. The demographics, treatment and outcome data were recorded in predesigned proforma. RESULTS:Data of 32 patients were r...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.150349

    authors: Mallick S,Benson R,Bhasker S,Mohanti BK

    更新日期:2015-01-01 00:00:00

  • What is the role of florine-18 fluorodeoxyglucose/positron emission tomography/computed tomography imaging in well-differentiated thyroid cancers with negative iodine-131 scan high thyroglobulin and normal anti-thyroglobulin levels.

    abstract:PURPOSE:This retrospective study aims to assess the cut-off value of thyroglobulin (Tg) levels in nux or metastatic well-differentiated thyroid cancers (DTCs) with normal anti-Tg levels using with fluorodeoxyglucose/positron emission tomography/computed tomography (FDG PET/CT). MATERIALS AND METHODS:We reviewed FDG PE...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.176412

    authors: Döner RK,Sager S,Görtan FA,Topuz ÖV,Akyel R,Vatankulu B,Baran A,Teksoz S,Sönmezoglu K

    更新日期:2016-04-01 00:00:00

  • Prevelance of prostate cancer among Turkish men with prostate-specific antigen level of ≤100 ng/ml.

    abstract:Aim of Study:Prostate cancer (PCa) is one of the most common cancers among men and has become a significant health problem in developing and developed countries. Prostate-specific antigen (PSA) is a useful marker for screening and monitoring the patients. In this study, the author aimed to detect the prevalence of PCa ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.187387

    authors: Çalışkan S

    更新日期:2018-10-01 00:00:00

  • Percutaneous thermal ablation combined with simultaneous transarterial chemoembolization for hepatocellular carcinoma ≤5 cm.

    abstract:Background/Aim:Percutaneous thermal ablation combined with transarterial chemoembolization (TACE) becomes a treatment option for unresectable hepatocellular carcinoma (HCC). This study aims to investigate the safety and feasibility of percutaneous thermal ablation combined with simultaneous TACE for patients with HCC ≤...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_250_19

    authors: Wu M,Gao S,Song H,Zhang Z,Wang J,Liu R,Wang X,Cheng J,Luo J,Liu Q,Chen Y,Yan Z,Liu L

    更新日期:2019-01-01 00:00:00

  • Critical biomarkers of epithelial-mesenchymal transition in the head and neck cancers.

    abstract::Epithelial-mesenchymal transition (EMT), a key developmental program has been shown to occur in wound healing, organ fibrosis and in the initiation of metastasis for cancer progression. EMT is a process that describes the development of motile, mesenchymal-like cells from non-motile parent epithelial cells. Plasticity...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.137926

    authors: Natarajan J,Chandrashekar C,Radhakrishnan R

    更新日期:2014-07-01 00:00:00

  • Massive scapular metastasis as a presenting feature of carcinoma of the lip.

    abstract::Carcinoma of the lip is a slow-growing locally-advanced disease with low metastatic potential. Distant skeletal metastasis is reported very rarely and the vertebral column is the most common site. A 58-year-old male smoker presented with pain and massive swelling of the left scapula for six months. He also noticed a s...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73338

    authors: Bandyopadhyay R,Nag D,Bandyopadhyay SK

    更新日期:2010-07-01 00:00:00

  • Large pedunculated lipoma of the esophagus: Report of a case and review of literature.

    abstract::Large pedunculated esophageal lipoma is uncommon. The presenting symptoms of esophageal lipoma are dysphagia, regurgitated mass, and persistent sensation of a lump in the throat. The most frequent location of the tumor pedicle is the upper esophageal sphincter. Here, we present the case of a 52-year-old man who had th...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件,评审

    doi:10.4103/0973-1482.154089

    authors: Qinying W,Wei L,Shuihong Z

    更新日期:2015-10-01 00:00:00

  • Epirubicin, oxaliplatin, and capectabine is just as "MAGIC"al as epirubicin, cisplatin, and fluorouracil perioperative chemotherapy for resectable locally advanced gastro-oesophageal cancer.

    abstract:BACKGROUND:The perioperative use of epirubicin, cisplatin, and fluorouracil (ECF) significantly improves outcomes in patients with gastric and gastro-oesophageal (GO) cancers but is cumbersome to administer. Given the equivalence of epirubicin, oxaliplatin, and capectabine (EOX) with ECF in advanced setting, we analyze...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.146122

    authors: Sirohi B,Barreto SG,Singh A,Batra S,Mittra A,Rastogia S,Ramadwar M,Shetty N,Goel M,Shrikhande SV

    更新日期:2014-10-01 00:00:00

  • A rare and unusual presentation of Epstein-Barr virus-associated diffuse large B-cell lymphoma involving colon as the primary site.

    abstract::Lymphoproliferative malignancies can involve both nodal- and extra-nodal tissues. The most common extranodal site involved is the gastrointestinal (GI) tract, and it is secondary to the widespread primary nodal disease. However, about 33% of non-Hodgkin's lymphoma primarily arise from tissues other than lymph nodes, s...

    journal_title:Journal of cancer research and therapeutics

    pub_type:

    doi:10.4103/jcrt.JCRT_239_17

    authors: Modi V,Bajaj N,Lakkasani S,Shaaban HS,Guron G

    更新日期:2020-01-01 00:00:00

  • Immunological subtypes analysis of Uygur diffuse large B-cell lymphoma in Xinjiang and their prognostic significance.

    abstract:OBJECTIVE:This study aims to explore the application of Choi's typing method in the immunological typing of diffuse large B-cell lymphoma (DLBCL) in Xinjiang Autonomous Region and its prognostic significance. MATERIALS AND METHODS:Seventy-eight cases of DLBCL tumor tissues from Xinjiang were collected to detect the ex...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.144357

    authors: Jia CD,Liang LP,Yang LL,Yue N,Zhao F,Bai JP

    更新日期:2015-10-01 00:00:00

  • A rarely seen mucoepidermoid carcinoma of the left main bronchus.

    abstract::Mucoepidermoid carcinomas (MEC) are rare malignant tumors that originate in the submucosal bronchial glands, and complete resection usually correlates with favorable prognosis. A 54-year-old male patient was diagnosed with high-grade MEC in the left main bronchus via bronchoscopy. After the patient was diagnosed with ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.136665

    authors: Kuzucuoglu M,Karamustafaoglu YA,Cicin I,Yoruk Y

    更新日期:2014-04-01 00:00:00

  • MRI diagnosis of intradural extramedullary tumors.

    abstract:OBJECTIVE:This study evaluates the magnetic resonance imaging (MRI) manifestation of intradural extramedullary (IDEM) tumors to improve the imaging diagnostic level. MATERIALS AND METHODS:From January 2005 to December 2012, a retrospective analysis of the MRI examination was performed on 108 patients with IDEM tumors ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.137993

    authors: Gu R,Liu JB,Zhang Q,Liu GY,Zhu QS

    更新日期:2014-10-01 00:00:00

  • Modern induction chemotherapy before chemoradiation for bulky locally-advanced nonsmall cell lung cancer improves survival.

    abstract:BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.177214

    authors: Ahmed I,Ferro A,Baby R,Malhotra J,Cohler A,Langenfeld J,Aisner J,Zou W,Jabbour SK

    更新日期:2016-04-01 00:00:00

  • Wnt5a/Ca (2+) /calcineurin/nuclear factor of activated T signaling pathway as a potential marker of pediatric melanoma.

    abstract::Melanoma is rare in children, but its incidence appears to be increasing. Melanoma accounts for the highest mortality among all skin cancer types. This disease is characterized by high-grade malignancy, easy metastasis, poor prognosis, and high death rate. Melanoma in children may be biologically different from that i...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.145788

    authors: Yang Y,Qian Q

    更新日期:2014-11-01 00:00:00

  • A correlation between oral mucosal lesions and various quid-chewing habit patterns: A cross-sectional study.

    abstract:Background and Objectives:Quid-chewing habit is a common and old tradition in India. It causes various potentially malignant disorders. Therefore, a study was undertaken to analyze the association of various quid-chewing habit patterns and different oromucosal lesions. Materials and Methods:A cross-sectional study was...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_620_14

    authors: Avinash Tejasvi ML,Anulekha CK,Afroze MM,Shenai KP,Chatra L,Bhayya H

    更新日期:2019-07-01 00:00:00

  • Anaplastic hemangiopericytoma of eyelid: An unusual location.

    abstract::Hemangiopericytomas (HPCs) are rare soft tissue tumors. The eyelid is a very uncommon site for these tumors, and an anaplastic variant of HPC in the eyelid has not been reported before. A 44-year-old male presented with complaints of slowly progressive, painless swelling on the inner aspect of the left upper eyelid fo...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.206240

    authors: Ventrapati P,Pathy S,Gandhi AK,Kashyap S

    更新日期:2017-01-01 00:00:00

  • Imbalance of T-helper 1/T-helper 2 cytokines and impaired glucose tolerance among patient with acute coronary syndrome.

    abstract:Purpose:The balance between T helper (Th) cells Th1- and Th2-related cytokines plays a key role in the clinical process of acute coronary syndrome (ACS) and type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT). The objective of this study was to assess the status of Th1/Th2 cytokines in patients with ACS...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.194346

    authors: Zhao SL,Mo ZH,He HH,Zhao LL,Xie YH

    更新日期:2018-06-01 00:00:00

  • Gastric cancer: a case study in Turkey.

    abstract:OBJECTIVE:The aim of this study was to determine age-specific incidence ratios, gastric cancer localization trend, histologic subtype and cancer related survival that whether have changed during the period from 1999 to 2010. MATERIALS AND METHODS:A total of 866 gastric cancer patients treated at the hospital were retr...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.126466

    authors: Tural D,Selçukbiricik F,Akar E,Serdengeçti S,Büyükünal E

    更新日期:2013-10-01 00:00:00

  • Survival of familial adenomatous polyposis coexistence colorectal cancer in Iran.

    abstract:Context:Familial adenomatous polyposis (FAP) is an autosomal dominant disorder. Colorectal cancer (CRC) has been implicated as the most common cause of death in FAP patients, especially in those with coexisting CRC at initial diagnosis (FAP-CRC). Aim:We aimed to determine the survival rate of FAP-CRC and the factors a...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_421_17

    authors: Mirinezhad SK,Moaddab SY,Bonyadi MJ,Shirmohammadi M,Eftekharsadat AT,Somi MH

    更新日期:2019-01-01 00:00:00

  • Live birth following in vitro fertilization in a breast cancer survivor: A case report and review of literature.

    abstract::The well-being of young cancer survivors is hampered due to the toxic effects of chemotherapy on the ovaries, resulting in infertility. We report a case of a 42-year-old woman with a history of bilateral ductal carcinoma of the breast who underwent radical mastectomy with chemotherapy and radiotherapy was anxious to c...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.174556

    authors: Muthuvel VA,Ravindran M,Chander VA,Gounder CV

    更新日期:2018-07-01 00:00:00

  • Renal cell carcinoma presenting with heart metastasis without inferior vena caval and right atrial involvement.

    abstract::Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.193111

    authors: Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

    更新日期:2018-01-01 00:00:00

  • The effect of metabolic syndrome on prostate cancer final pathology.

    abstract:Aim of Study:Metabolic syndrome (MetS) is an abnormality that increases the risk of cardiovascular disease and diabetes. In the recent years, studies showed that MetS is associated with increased risk of incidence, aggressiveness, and mortality of prostate cancer (PCa). We examined the influence of MetS at final pathol...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.187290

    authors: Caliskan S,Kaba S,Özsoy E,Keleş MO,Koca O,Akyüz M,Karaman MI

    更新日期:2019-03-01 00:00:00

  • Elevated expression of matrix metalloproteinase-9 is associated with bladder cancer pathogenesis.

    abstract:Objective:This study investigated the association between abnormal matrix metalloproteinase-9 (MMP-9) expression and bladder cancer (BC) development. Materials and Methods:In a retrospective analysis, this study used tissue samples derived from 92 patients pathologically diagnosed with BC (experimental group), who wer...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.163761

    authors: Wu GJ,Bao JS,Yue ZJ,Zeng FC,Cen S,Tang ZY,Kang XL

    更新日期:2018-01-01 00:00:00