Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer.

Abstract:

BACKGROUND:Tumor markers are a major part of the secondary prevention and thus the detection of malignancies. Neoplasms often have an increased concentration of sialic acid on the tumor cell surface and are shed or secreted by some of these cells which increase the concentration in blood. MATERIALS AND METHODS:The study was conducted on 90 subjects equally divided into three groups viz, healthy individuals, oral cancer and precancer. The estimation of serum total sialic acid level was done according to Plucinsky et al by resorcinol reagent method. The statistical analysis was carried out by using SPSS 10.0 software. RESULTS:The mean serum total sialic acid (TSA) level in oral precancer and oral cancer group was statistically significant (P<0.05). In oral cancer group when stage I and stage II were compared with stage III and stage IV, it was statistically significant (P<0.05). Histopathologically, oral cancer and precancer did not show statistically significant values (P>0.05). The present study also suggested that no correlation exists between habit of tobacco chewing / betel nut chewing / smoking or alcohol consumption with that of serum total sialic acid levels. CONCLUSION:Serum total sialic acid levels can be used as an adjunctive diagnostic marker in head and neck cancer.

journal_name

J Cancer Res Ther

authors

Joshi M,Patil R

doi

10.4103/0973-1482.73339

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

263-6

issue

3

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2010_6_3_263_73339

journal_volume

6

pub_type

杂志文章
  • Intractable nausea in a patient with synchronous pancreatic cancer and a fourth-ventricular ependymoma.

    abstract::Symptoms of nausea and vomiting can present a diagnostic challenge for physicians. In this article, we report a patient who was found to have synchronous presentation of an ependymoma and pancreatic cancer. This case illustrates some of the diagnostic challenges in patients with constitutional symptoms. Furthermore, i...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.126474

    authors: Chowdhry VK,Carter DA,Shapiro A

    更新日期:2013-10-01 00:00:00

  • Anaplastic hemangiopericytoma of eyelid: An unusual location.

    abstract::Hemangiopericytomas (HPCs) are rare soft tissue tumors. The eyelid is a very uncommon site for these tumors, and an anaplastic variant of HPC in the eyelid has not been reported before. A 44-year-old male presented with complaints of slowly progressive, painless swelling on the inner aspect of the left upper eyelid fo...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.206240

    authors: Ventrapati P,Pathy S,Gandhi AK,Kashyap S

    更新日期:2017-01-01 00:00:00

  • Immunohistochemical study of the expression of human chorionic gonadotropin-β in salivary gland tumors.

    abstract:Background and Objectives:Human chorionic gonadotropin-β (hCGβ) is a hormone glycoprotein usually secreted by trophoblastic cells in early pregnancy and helps in growth and development of the embryo. While many trophoblastic and nontrophoblastic malignancies express elevated levels of hCGβ in serum, increased immunohis...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.184523

    authors: Meda S,Reginald BA,Reddy BS

    更新日期:2018-07-01 00:00:00

  • SiRNA and epigenetic aberrations in ovarian cancer.

    abstract::Ovarian cancer has the most noteworthy lethal rate around gynecologic malignancies, and it is also considered as the fourth most frequent cancer in the woman in world. Two most critical barriers to treatment of ovarian malignancy are absence of early diagnostic markers and advancement of drug resistance after therapy,...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.153661

    authors: Mirzaei H,Yazdi F,Salehi R,Mirzaei HR

    更新日期:2016-04-01 00:00:00

  • CT findings in non-small-cell lung cancer patients treated with gefitinib or erlotinib.

    abstract:PURPOSE:We performed this study to explore the association of computed tomography (CT) findings with outcomes of patients with non-small-cell lung cancer (NSCLC) treated with tyrosin kinase inhibitor (TKI) such as gefitinib or erlotinib. MATERIALS AND METHODS:We analyzed outcomes for 240 patients according to primary ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.98979

    authors: Na II,Choe du H,Kim CH,Park SH,Park JH,Lee JC

    更新日期:2012-04-01 00:00:00

  • The impact of perioperative blood transfusion on survival and recurrence after radical prostatectomy for prostate cancer: A systematic review and meta-analysis.

    abstract:Objective:Conflicting data have been reported regarding the association between perioperative blood transfusion (PBT) and clinical outcomes for prostate cancer patients. We conducted a systematic review and meta-analysis to evaluate the impact of PBT on cancer survival and recurrence for patients who underwent radical ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,meta分析,评审

    doi:10.4103/0973-1482.193115

    authors: Pushan Z,Manbiao C,Sulai L,Jun L,Ruidong Z,Hanshen Y

    更新日期:2018-09-01 00:00:00

  • A 36-year-old female with Krukenberg tumor from a colonic carcinoma.

    abstract::Krukenberg tumor is bilateral ovarian carcinoma's metastasizing most commonly from a gastric primary followed by a colon. We report a case of 36-year-old female with bilateral ovarian mass diagnosed as Krukenberg with a work up for locating the primary site. In this case, we discuss widely the clinical aspects with hi...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.167615

    authors: Umakanthan S,Bukelo MM,Hardik K

    更新日期:2015-10-01 00:00:00

  • Treatment outcomes of malignant fibrous histiocytoma of the maxillary sinus.

    abstract:BACKGROUND:Malignant fibrous histiocytoma (MFH) is an uncommon neoplasm of maxillary sinus. This study was designed to investigate the clinical courses and summarize the experience of the treatment outcomes. MATERIALS AND METHODS:This is a retrospective analysis which included patients with MFH of the maxillary sinus ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_29_17

    authors: Huang H,Li D,Wang X,Wu Y,Liu S,Xu Z

    更新日期:2017-01-01 00:00:00

  • Primary papillary thyroid carcinoma previously treated incompletely with radiofrequency ablation.

    abstract::Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73328

    authors: Kim HY,Ryu WS,Woo SU,Son GS,Lee ES,Lee JB,Bae JW

    更新日期:2010-07-01 00:00:00

  • Potent chemopreventive effect of mangiferin on lung carcinogenesis in experimental Swiss albino mice.

    abstract:AIM OF THE STUDY:In the present study the effects of mangiferin were tested against lung cancer-bearing mice in both the pre-initiation and post-initiation periods. MATERIALS AND METHODS:Healthy male Swiss albino mice (6-8 weeks old) were used throughout the study. The animals were treated with mangiferin (100 mg/kg b...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.137966

    authors: Rajendran P,Rengarajan T,Nishigaki I,Ekambaram G,Sakthisekaran D

    更新日期:2014-10-01 00:00:00

  • Chordoid meningioma: A diagnostic dilemma.

    abstract::Chordoid meningioma (CM), classified as Grade II/atypical meningioma according to the World Health Organization classification, is a rare subtype, which represents only 0.5% of all meningiomas. Morphologically, it can mimic other chondroid and myxoid tumors within the brain and its vicinity thus posing a diagnostic ch...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.144656

    authors: Siraj F,Ansari MK,Sharma KC,Singh A

    更新日期:2015-07-01 00:00:00

  • Breast-conserving surgery versus modified radical mastectomy in treatment of early stage breast cancer: A retrospective study of 107 cases.

    abstract:OBJECTIVE:The aim of this retrospective study was to evaluate the clinical efficacy and prognosis of breast-conserving surgery versus modified radical mastectomy in the treatment of early stage breast cancer. PATIENTS AND METHODS:Two hundred and nineteen cases of early stage breast cancer were reviewed and retrospecti...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.163835

    authors: Chen Z,Xu Y,Shu J,Xu N

    更新日期:2015-08-01 00:00:00

  • MicoRNA-451 is a novel tumor suppressor via targeting c-myc in head and neck squamous cell carcinomas.

    abstract:OBJECTIVE:Head and neck squamous cell carcinoma (HNSCC) represents as a common malignancy with increasing incidence in the worldwide. The fact of its poor survival rate urgently requires developing efficient predictive biomarkers for clinical use. MicroRNAs (miRNAs) recently represent as a novel direction for early dia...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.168189

    authors: Wang H,Zhang G,Wu Z,Lu B,Yuan D,Li X,Lu Z

    更新日期:2015-10-01 00:00:00

  • Evaluation of clinical process in osteosarcoma patients treated with chemotherapy including cisplatin, adriamycin, ifosfamide, and etoposide and determination of the treatment sequels in a long-term 11-year follow-up.

    abstract:AIM:The aim of this study was to evaluate the effect of adding etoposide and ifosfamide chemotherapy drugs to treatment regimen of patients affected with osteosarcoma and to determine the clinical process and response to treatment during a follow-up period of 11 years. MATERIALS AND METHODS:Forty patients with osteosa...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.199447

    authors: Aznab M,Hematti M

    更新日期:2017-04-01 00:00:00

  • The overexpression of MRP4 is related to multidrug resistance in osteosarcoma cells.

    abstract::Doxorubicin (Adriamycin, ADM) is an antimitotic drug used in the treatment of a wide range of malignant tumors, including acute leukemia, lymphoma, osteosarcoma, breast cancer, and lung cancer. Multidrug resistance-associated proteins (MRPs) are members of a superfamily of ATP-binding cassette (ABC) transporters, whic...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.143334

    authors: He Z,Hu B,Tang L,Zheng S,Sun Y,Sheng Z,Yao Y,Lin F

    更新日期:2015-01-01 00:00:00

  • Breast cancer tumor type recognition using graph feature selection technique and radial basis function neural network with optimal structure.

    abstract:Context:Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims:In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design:The proposed system includes three m...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.183561

    authors: Zarbakhsh P,Addeh A

    更新日期:2018-04-01 00:00:00

  • Transnasal endoscopic resection of vascular leiomyomas of the nasal septum.

    abstract:OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.150417

    authors: Chen HH,Wang QY,Zhou SH

    更新日期:2016-01-01 00:00:00

  • Renal cell carcinoma presenting with heart metastasis without inferior vena caval and right atrial involvement.

    abstract::Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.193111

    authors: Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

    更新日期:2018-01-01 00:00:00

  • Metastatic malignant melanoma affecting stomach.

    abstract::Malignant melanoma has been reported to affect all organs of the human body with the metastasis. Stomach metastases are quite rare in cases of the most commonly reported primaries including, melanoma and breast, and lung carcinomas. This report involves, a 56-year-old man suffering from melanoma of the lower extremity...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.136029

    authors: Eivazi-Ziaei J,Esmaili H

    更新日期:2014-07-01 00:00:00

  • Impact of Gleason pattern up gradation after radical prostatectomy for carcinoma prostate patients with low biopsy score (≤ 6).

    abstract:CONTEXT:Biopsy Gleason score (b-GS) is often different from the Gleason score obtained after analysis of radical prostatectomy (RP) specimen (rp-GS). Upgradation has an important implication in decision making for cancer prostate management, and is the focus of this study. AIM:To evaluate Gleason score upgradation aft...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.92021

    authors: Kulkarni JN,Valsangkar RS,Jadhav YR,Singh DP

    更新日期:2011-10-01 00:00:00

  • Burkitt's lymphoma of the humerus.

    abstract::Burkitt's lymphoma is an uncommon form of non-Hodgkin's lymphoma (NHL) in adults and represents < 5% of NHL adults. Burkitt's lymphoma involving primarily the appendicular skeleton is rarely described. We present the case of a young man with primary Burkitt's lymphoma involving the humerus as the only site of disease....

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.148678

    authors: Geetha N,Sreelesh KP,Nair RA,Jacob PM

    更新日期:2015-10-01 00:00:00

  • Impact of subventricular zone irradiation on outcome of patients with glioblastoma.

    abstract:Purpose:Glioblastoma (GBM) is characterized by early relapse and mortality. Treatment resistance could be a characteristic exhibited by pro-genitor neoplastic cells that reside in the subventricular zone (SVZ). This retrospective study was conducted to assess the correlation of SVZ doses and survival in patients with G...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_295_17

    authors: Mathew BS,Kaliyath SB,Krishnan J,Bhasi S

    更新日期:2018-10-01 00:00:00

  • Ultrasonographic diagnosis of benign masseter muscle hypertrophy: A case report.

    abstract::Masseter hypertrophy is a characteristic condition resulting from an increase in the size of the muscle mass. At times, it produces significant facial asymmetry and is an important finding in the differential diagnosis of similar located entities. A proper diagnosis of this condition would avoid more aggressive and un...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.204889

    authors: Naphade VV,Kedia SG,Patil P,Khare S

    更新日期:2018-12-01 00:00:00

  • Adenocarcinoma in a tailgut cyst: A rare case report.

    abstract::Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/jcrt.JCRT_212_17

    authors: Valecha J,Ojha SS,Sharma A,Nilkanthe R

    更新日期:2019-01-01 00:00:00

  • Identification of significant ego networks and pathways in rheumatoid arthritis.

    abstract:Objective:The objective of this paper is to identify ego networks and pathways in rheumatoid arthritis (RA) based on EgoNet algorithm and pathway enrichment analysis. Materials and Methods:The ego networks were identified based on the EgoNet algorithm which was comprised four steps: inputting gene expression data and ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.189250

    authors: Zhou WZ,Miao LG,Yuan H

    更新日期:2018-12-01 00:00:00

  • Analysis of hepatocellular carcinoma and metastatic hepatic carcinoma via functional modules in a protein-protein interaction network.

    abstract:INTRODUCTION:This study aims to identify protein clusters with potential functional relevance in the pathogenesis of hepatocellular carcinoma (HCC) and metastatic hepatic carcinoma using network analysis. MATERIALS AND METHODS:We used human protein interaction data to build a protein-protein interaction network with C...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.145866

    authors: Pan J,Cong Z,Zhong M,Sun Y

    更新日期:2014-11-01 00:00:00

  • Pulmonary toxicity following bleomycin use: A single-center experience.

    abstract:BACKGROUND:Bleomycin-induced pulmonary (BIP) toxicity is a notorious entity and cropped up in roughly 10% of cases. The aim of the study is to evaluate BIP at our tertiary care cancer center. PATIENTS AND METHODS:This is a retrospective, analytical study conducted at a tertiary care center from January 1998 to Decembe...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.204887

    authors: Madabhavi I,Modi G,Patel A,Anand A,Panchal H,Parikh S

    更新日期:2017-07-01 00:00:00

  • Efficacy of tyrosine kinase inhibitors in routine clinical practice: epidermal growth factor mutations and their implications.

    abstract:BACKGROUND:Activating mutations in the epidermal growth factor (EGFR) gene confer sensitivity to the tyrosine kinase inhibitors (TKIs) in patients with advanced non-small cell lung cancer (NSCLC). TKI treatment efficacy and EGFR mutation implications were evaluated in clinically selected advanced NSCLC patients treated...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.113379

    authors: Ovcaricek T,Cufer T,Kern I,Sodja E,Sadikov A

    更新日期:2013-04-01 00:00:00

  • Frequency of epidermal growth factor receptor mutations in Jordanian lung adenocarcinoma patients at diagnosis.

    abstract:BACKGROUND:Somatic mutations of the epidermal growth factor receptor (EGFR) gene have been associated with tumor response to tyrosine kinase inhibitors (TKIs) and favorable outcome in patients with non-small-cell lung cancer (NSCLC). The activating mutations that confer sensitivity to EGFR TKIs are present in the TK do...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.147711

    authors: Obeidat N,Awidi A,Ababneh N,Shomaf M,Al-Adaily T,Jaber M,Al-Khateeb M,Abbasi S

    更新日期:2016-04-01 00:00:00

  • Neoadjuvant chemotherapy in patients with locally advanced breast cancer: A pilot-observational study.

    abstract:BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.146056

    authors: Dodiya HG,Brahmbhatt AP,Khatri PK,Kaushal AM,Vijay DG

    更新日期:2015-07-01 00:00:00