Development of plasma cell leukemia in a patient with chronic myeloid leukemia while on treatment with imatinib mesylate.

Abstract:

:Plasma cell leukemia (PCL) is a rare and an aggressive form of plasma cell dyscrasias. We report a 67-year-old male with PCL which developed while on imatinib mesylate (IM) therapy 38 months after diagnosis of chronic myeloid leukemia (CML). The patient has been treated successfully with bortezomib, melphalan and prednisolone. To our knowledge, only one case of PCL superimposed on Philadelphia positive CML has been reported in the literature and this was before the IM era.

journal_name

J Cancer Res Ther

authors

Maral S,Bakanay SM,Yikilmaz AS,Dilek I

doi

10.4103/0973-1482.192762

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

1431-1433

issue

6

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2018_14_6_1431_192762

journal_volume

14

pub_type

信件
  • Value of intravoxel incoherent motion magnetic resonance imaging for differentiating metastatic from nonmetastatic mesorectal lymph nodes with different short-axis diameters in rectal cancer.

    abstract:Background:Conventional magnetic resonance imaging (MRI) does not accurately evaluate lymph node (LN) status, which is essential for the treatment and prognosis assessment in patients with rectal cancer. Objective:The aim of this study is to evaluate the diagnostic value of intravoxel incoherent motion (IVIM) MRI in d...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_76_19

    authors: Long L,Zhang H,He X,Zhou J,Guo D,Liu X

    更新日期:2019-01-01 00:00:00

  • The expression and prognostic significance of Mucin 13 and Mucin 20 in esophageal squamous cell carcinoma.

    abstract:BACKGROUND:Mucin 13 (MUC13) and Mucin 20 (MUC20) are high molecular weight transmembrane O-linked glycoprotein secreted by epithelium and are widely overexpressed in epithelial tumor cells. Previously, it has been reported that MUC13 and MUC20 were prognostic molecular biomarkers of some epithelial tumors, but few has ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.163846

    authors: Wang H,Shen L,Lin Y,Shi Q,Yang Y,Chen K

    更新日期:2015-08-01 00:00:00

  • Endoscopic ultrasonography-guided poly (lactic acid-co-glycolic acid)-poly (ethylene glycol)-poly (lactic acid-co-glycolic acid) thermogel tunnel creation for natural orifice transluminal endoscopic surgery in porcine model.

    abstract:Background:Natural orifice transluminal endoscopic surgery (NOTES) is a minimal invasive treatment. However, tissue dissection under endoscopy is still challenging due to the flexibility of endoscopy body and there is still no effective method for establishing a tunnel towards the targeted area. We previously showed th...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_400_18

    authors: Sun X,Yu L,Zhu J,Zu S,Ding J,Liu Y

    更新日期:2019-01-01 00:00:00

  • Management of the neck in early oral cancers: Is the verdict out?

    abstract::The management of patients with the clinically negative neck (N0) in early oral cancers awaits a clear mandate despite growing evidence favoring elective neck dissection. Having a general policy of operating all N0 neck may indeed increase the number of unnecessary neck dissection in the true pathological N0 necks, a ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.164705

    authors: Rao VU,Patil PH,Rajaram BV

    更新日期:2016-07-01 00:00:00

  • Clinical significance of Twist, E-cadherin, and N-cadherin protein expression in endometrioid adenocarcinoma.

    abstract:OBJECTIVE:The aim of the study was to investigate the expression of Twist, E-cadherin, and N-cadherin both in normal endometrium and in endometrioid adenocarcinoma tissues (NET and EAT), and further discuss the relationship between the proteins expression and the clinical parameters. METHODS:Seventy-six EAT and 50 NET...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_405_17

    authors: Xie X,Zheng X,Wang J,Chen L

    更新日期:2017-01-01 00:00:00

  • Pulmonary toxicity following bleomycin use: A single-center experience.

    abstract:BACKGROUND:Bleomycin-induced pulmonary (BIP) toxicity is a notorious entity and cropped up in roughly 10% of cases. The aim of the study is to evaluate BIP at our tertiary care cancer center. PATIENTS AND METHODS:This is a retrospective, analytical study conducted at a tertiary care center from January 1998 to Decembe...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.204887

    authors: Madabhavi I,Modi G,Patel A,Anand A,Panchal H,Parikh S

    更新日期:2017-07-01 00:00:00

  • Breast cancer tumor type recognition using graph feature selection technique and radial basis function neural network with optimal structure.

    abstract:Context:Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims:In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design:The proposed system includes three m...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.183561

    authors: Zarbakhsh P,Addeh A

    更新日期:2018-04-01 00:00:00

  • Precision dose measurement of 125I seed in solid water through SPECT/CT detecting.

    abstract:Purpose:The aim of the study is to study the feasibility of gamma-ray-detection-based precision dose measurement of 125I seed brachytherapy in solid water. Materials and Methods:Seven group 125I seeds with different activities were put into a hole in the center of solid water individually. Each group had ten seeds, an...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_522_18

    authors: Zhang H,Liang Y,Qiu G,Wang Z,Dev D,Liu Z,Li H,Yu H,Chen J,Sui A,Wang J,Shi G

    更新日期:2019-01-01 00:00:00

  • Genetic variants identified by GWAS was associated with colorectal cancer in the Han Chinese population.

    abstract:AIM OF STUDY:Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. Recently, genome-wide association studies have identified two single nucleotide polymorphisms (SNP) associated with CRC in Caucasians. MATERIALS AND METHODS:To validate whether the same variation...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.150346

    authors: Qiao HP,Zhang CY,Yu ZL,Li QM,Jiao Y,Cao JP

    更新日期:2015-04-01 00:00:00

  • MRI diagnosis of intradural extramedullary tumors.

    abstract:OBJECTIVE:This study evaluates the magnetic resonance imaging (MRI) manifestation of intradural extramedullary (IDEM) tumors to improve the imaging diagnostic level. MATERIALS AND METHODS:From January 2005 to December 2012, a retrospective analysis of the MRI examination was performed on 108 patients with IDEM tumors ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.137993

    authors: Gu R,Liu JB,Zhang Q,Liu GY,Zhu QS

    更新日期:2014-10-01 00:00:00

  • Epidural analgesia during brachytherapy for cervical cancer patients.

    abstract:AIMS:To find out the efficacy of epidural analgesia in providing continuous pain relief for patients undergoing brachytherapy for cervical cancer. SETTINGS:Teaching Hospital. DESIGN:Retrospective Study. MATERIALS AND METHODS:A total of 152 patients of cervical cancer received epidural analgesia during 18 to 21 hours...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.40825

    authors: Janaki MG,Nirmala S,Kadam AR,Ramesh BS,Sunitha KS

    更新日期:2008-04-01 00:00:00

  • Acinic cell carcinoma of the posterior buccal mucosa: A rare case report.

    abstract::Acinic cell carcinoma (ACC) is a low-grade malignant salivary gland neoplasm that comprises approximately 17% of primary salivary gland malignancies or about 6% of all salivary gland neoplasms. The most common intraoral sites are the buccal mucosa, lips, and palate. The diagnosis of ACC frequently presents difficultie...

    journal_title:Journal of cancer research and therapeutics

    pub_type:

    doi:10.4103/jcrt.JCRT_399_18

    authors: Babu SS,Sunil S,Prathap A,Mathew AL

    更新日期:2020-04-01 00:00:00

  • Adenocarcinoma located at a Meckel's Diverticulum: A case report and literature review.

    abstract::Tumors arising from Meckel's diverticulum (MD) reported in the literature are mainly carcinoid and gastrointestinal stromal tumors. We herein report a rare case of adenocarcinoma arising from intestinal mucosa in an MD with multiple liver metastases at the onset of symptoms. A 57-year-old female complaining of bloody ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件,评审

    doi:10.4103/jcrt.JCRT_124_17

    authors: Zhao Y,Yang X,Ye Y

    更新日期:2017-01-01 00:00:00

  • CT findings in non-small-cell lung cancer patients treated with gefitinib or erlotinib.

    abstract:PURPOSE:We performed this study to explore the association of computed tomography (CT) findings with outcomes of patients with non-small-cell lung cancer (NSCLC) treated with tyrosin kinase inhibitor (TKI) such as gefitinib or erlotinib. MATERIALS AND METHODS:We analyzed outcomes for 240 patients according to primary ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.98979

    authors: Na II,Choe du H,Kim CH,Park SH,Park JH,Lee JC

    更新日期:2012-04-01 00:00:00

  • Surface activity, lipid profiles and their implications in cervical cancer.

    abstract:BACKGROUND:The profiles of lipids in normal and cancerous tissues may differ revealing information about cancer development and progression. Lipids being surface active, changes in lipid profiles can manifest as altered surface activity profiles. Langmuir monolayers offer a convenient model for evaluating surface activ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.19600

    authors: Preetha A,Banerjee R,Huilgol N

    更新日期:2005-07-01 00:00:00

  • Intra-arterial chemotherapy as second-line treatment for advanced retinoblastoma: A 2-year single-center study in China.

    abstract:Purpose:To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort. Patients and Methods:Eighty-four eyes of 62 consecutive patients with advanced refractory RB who received IAC were included in the study dur...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_722_17

    authors: Hua J,Gang S,Yizhou J,Jing Z

    更新日期:2018-01-01 00:00:00

  • Orbital alveolar soft-part sarcoma: clinico-pathological profiles, management and outcomes.

    abstract:AIM:To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). MATERIALS AND METHODS:We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. RESULTS:Age at presentation varied from...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.136570

    authors: Mulay K,Ali MJ,Honavar SG,Reddy VA

    更新日期:2014-04-01 00:00:00

  • CLIC1 overexpression is associated with poor prognosis in pancreatic ductal adenocarcinomas.

    abstract:BACKGROUND:Clinical significance of chloride intracellular channel 1 (CLIC1) in pancreatic ductal adenocarcinomas (PDAC) remains largely unknown. This study was performed to assess the expression of CLIC1 in benign and malignant pancreatic lesions, and to assess its clinicopathological significance. MATERIALS AND METH...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.154057

    authors: Jia N,Dong S,Zhao G,Gao H,Li X,Zhang H

    更新日期:2016-04-01 00:00:00

  • Hypofractionated radiotherapy in carcinoma breast: What we have achieved?

    abstract::Healthy breast tissue is sensitive to radiation fraction size, such that small changes in fraction size can lead to larger changes in radiation effects on these tissues. Conventional breast and/or chest wall irradiation uses 2 Gy daily fractions, for 5-6 weeks. Such a long treatment schedule has major implications on ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.157342

    authors: Bhattacharyya T,Mahajan R,Ghoshal S,Yadav BS,Rai B

    更新日期:2015-04-01 00:00:00

  • Angiogenesis and mast cell density as predictors of patient survival in squamous cell carcinoma of lung.

    abstract:BACKGROUND:Measuring the microvascular and mast cell density in squamous cell carcinoma of lung and correlating them with the patient survival may be helpful to guide the use of cancer chemotherapeutic agents which target molecular mechanisms of tumour angiogenesis and mast cells. MATERIALS AND METHODS:It was an obser...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.126487

    authors: Ullah E,Nagi AH,Ashraf M

    更新日期:2013-10-01 00:00:00

  • Antitumoral potential of microvesicles extracted from human adipose-derived mesenchymal stem cells on human breast cancer cells.

    abstract:Aim of Study:One of the new methods that have promising results is the use of cell-derived microvesicles (MVs) to kill tumor cells. Given that MVs contain apoptotic materials, genes, and proteins, they can interfere with the fate of adjacent cells. Materials and Methods:In the present study, after adipose tissue-deriv...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_147_18

    authors: Rezaie Z,Ardeshirylajimi A,Ashkezari MD,Seifati SM

    更新日期:2019-07-01 00:00:00

  • Epirubicin, oxaliplatin, and capectabine is just as "MAGIC"al as epirubicin, cisplatin, and fluorouracil perioperative chemotherapy for resectable locally advanced gastro-oesophageal cancer.

    abstract:BACKGROUND:The perioperative use of epirubicin, cisplatin, and fluorouracil (ECF) significantly improves outcomes in patients with gastric and gastro-oesophageal (GO) cancers but is cumbersome to administer. Given the equivalence of epirubicin, oxaliplatin, and capectabine (EOX) with ECF in advanced setting, we analyze...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.146122

    authors: Sirohi B,Barreto SG,Singh A,Batra S,Mittra A,Rastogia S,Ramadwar M,Shetty N,Goel M,Shrikhande SV

    更新日期:2014-10-01 00:00:00

  • Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer.

    abstract:BACKGROUND:Tumor markers are a major part of the secondary prevention and thus the detection of malignancies. Neoplasms often have an increased concentration of sialic acid on the tumor cell surface and are shed or secreted by some of these cells which increase the concentration in blood. MATERIALS AND METHODS:The stu...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73339

    authors: Joshi M,Patil R

    更新日期:2010-07-01 00:00:00

  • Renal cell carcinoma presenting with heart metastasis without inferior vena caval and right atrial involvement.

    abstract::Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.193111

    authors: Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

    更新日期:2018-01-01 00:00:00

  • Computed tomography-guided percutaneous microwave ablation for treatment of peripheral ground-glass opacity-Lung adenocarcinoma: A pilot study.

    abstract:Purpose:The purpose of the study is to retrospectively evaluate the safety and efficacy of microwave ablation (MWA) for the treatment of ground-glass opacity (GGO)-lung adenocarcinoma. Materials and Methods:From December 2013 to June 2017, a total of 51 patients (22 males and 29 females, mean age of 69.4 ± 10.1 years)...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_269_18

    authors: Yang X,Ye X,Lin Z,Jin Y,Zhang K,Dong Y,Yu G,Ren H,Fan W,Chen J,Lin Q,Huang G,Wei Z,Ni Y,Li W,Han X,Meng M,Wang J,Li Y

    更新日期:2018-01-01 00:00:00

  • Down-expression of circulating micro ribonucleic acid (miRNA)-148/152 family in plasma samples of non-small cell lung cancer patients.

    abstract:AIMS:Circulating extracellular micro ribonucleic acids (miRNAs) are considered as potential biomarkers for malignancy detection and diagnosis. The aim of this study was to determine whether circulating miRNA-148/152 family (miR-148a, miR-148b, and miR-152) expression in plasma could be used as potential biomarkers for ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.150420

    authors: Huang MX

    更新日期:2016-04-01 00:00:00

  • Primary pulmonary epithelioid angiosarcoma: A case report and literature review.

    abstract::Primary pulmonary epithelioid angiosarcoma is an extremely rare malignancy. Herein, we report the case of an elderly Chinese patient with primary pulmonary epithelioid angiosarcoma. The 72-year-old man presented with a 1-month history of persistent hemoptysis and left chest pain and weight loss of 3 kg. A chest comput...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件,评审

    doi:10.4103/0973-1482.176419

    authors: Zhang Y,Huang X,Peng C,Wang Y,Wu Q,Wu Z,Shao H,Wang W

    更新日期:2018-06-01 00:00:00

  • Occupational doses of cardiologists in cath labs and simulation method.

    abstract::In recent years, using the ionizing radiation in the interventional cardiology has been increased; this is because of the rapid growth of the number of interventional procedures and the high levels of radiation dose in these examinations. Therefore, it is necessary to develop procedures for managing the use of fluoros...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.192767

    authors: Fardid R,Mirzadeh F,Rezaei H

    更新日期:2017-10-01 00:00:00

  • Oral biopsy: oral pathologist's perspective.

    abstract::Many oral lesions may need to be diagnosed by removing a sample of tissue from the oral cavity. Biopsy is widely used in the medical field, but the practice is not quite widespread in dental practice. As oral pathologists, we have found many artifacts in the tissue specimen because of poor biopsy technique or handling...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.98969

    authors: Kumaraswamy KL,Vidhya M,Rao PK,Mukunda A

    更新日期:2012-04-01 00:00:00

  • Wnt5a/Ca (2+) /calcineurin/nuclear factor of activated T signaling pathway as a potential marker of pediatric melanoma.

    abstract::Melanoma is rare in children, but its incidence appears to be increasing. Melanoma accounts for the highest mortality among all skin cancer types. This disease is characterized by high-grade malignancy, easy metastasis, poor prognosis, and high death rate. Melanoma in children may be biologically different from that i...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.145788

    authors: Yang Y,Qian Q

    更新日期:2014-11-01 00:00:00