Abstract：
BACKGROUND:Oral cancer (OC) mortality is very high in Sudan, particularly among men due to the habit of Toombak use (tobacco specific nitrose amine (TSN)) rich tobacco. AIMS:Our aim was to determine whether OC is gender-specific due to increased Toombak use among males as suggested a risk for subsequent development of oral cancer. SETTINGS AND DESIGN:We conducted a descriptive study of OC in Khartoum and obtained information on Toombak use, confounding variables for 39 incident patients with oral cancerous lesions and 43 hospital-based cases without apparent oral lesions. MATERIALS AND METHODS:OC was affirmed by histopathology for all patients with oral lesions, hence oral epithelial atypia and leukoplakias were detected using cytology. STATISTICAL ANALYSIS:Data analyzed using a computer SPSS program. RESULTS AND CONCLUSIONS:Of the 82 subjects, there were 57 (70%) Toombak users and 25 (30%) non-tobacco users. Among the 39 patients with OC, 24 (61.5%) were Toombak users and 15 (38.5%) were non-tobacco users. Among 43 with atypical changes, 10 (23.3%) were non-tobacco users and 33 (76.7%) were Toombak users. Regarding gender, only 11 (13.4%) were females, of whom 8 (72.7%) were non-tobacco users. We conclude that oral cancer, atypia and leukoplakia were high among males who were Toombak users. In view of the high incidence (29%) of OC due to Toombak use, we propose the implementation of oral screening programme restricted to Toombak users.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Ahmed HG,Mahgoob RMdoi
10.4103/0973-1482.34696subject
Has Abstractpub_date
2007-04-01 00:00:00pages
127-30issue
2eissn
0973-1482issn
1998-4138journal_volume
3pub_type
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journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
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