CLIC1 overexpression is associated with poor prognosis in pancreatic ductal adenocarcinomas.

abstract：BACKGROUND:The overall goal of this study is to use a bacterial toxin as drug delivery agents for chemotherapy drugs and overcome the development of resistance to these medicines. COR-L105 and MDA-MB 231 which are epithelial-like were used in this study. Cytotoxicity assays were performed by 3-(4, 5-dimethyl-2-thiazoly...

journal_title：Journal of cancer research and therapeutics

authors： Shekarsaraei AG,Hasannia S,Pirooznia N,Ataiee F

更新日期：2014-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Currently, the main effective treatment options for HCC include resection, liver transplantation, various percutaneous modalities (such as transarterial chemoembolization [TACE] and thermal ablation), and tyrosine kinase inhibitors (TKIs). Here...

journal_title：Journal of cancer research and therapeutics

authors： Meng M,Li W,Yang X,Huang G,Wei Z,Ni Y,Han X,Wang J,Ye X

更新日期：2020-01-01 00:00:00

abstract：AIM OF THE STUDY:In the present study the effects of mangiferin were tested against lung cancer-bearing mice in both the pre-initiation and post-initiation periods. MATERIALS AND METHODS:Healthy male Swiss albino mice (6-8 weeks old) were used throughout the study. The animals were treated with mangiferin (100 mg/kg b...

journal_title：Journal of cancer research and therapeutics

authors： Rajendran P,Rengarajan T,Nishigaki I,Ekambaram G,Sakthisekaran D

更新日期：2014-10-01 00:00:00

abstract：:Primary neuroendocrine carcinoma of the female genital tract is a rare entity with aggressive clinical behavior and a poor prognosis. This kind of malignancy arising in the vagina is extremely rare. We report a case of primary neuroendocrine carcinoma of vagina arising in a setting of atypical vaginal adenosis. ...

journal_title：Journal of cancer research and therapeutics

authors： Khurana A,Gupta G,Gupta M,Kaur M

更新日期：2013-04-01 00:00:00

abstract：Objectives:Apatinib, a tyrosine kinase inhibitor which selectively inhibits vascular endothelial growth factor receptor-2, has been shown to be beneficial to patients with a variety of cancers, including advanced nonsmall-cell lung cancer (NSCLC). Thus, this study was aimed to retrospectively assess the efficacy and sa...

journal_title：Journal of cancer research and therapeutics

authors： Yang C,Feng W,Wu D

更新日期：2018-01-01 00:00:00

abstract：Aim:The aim of this study is to identify an ideal location of isocenter in intensity-modulated radiotherapy (IMRT) treatment plans. Materials and Methods:A total of 28 clinical target volumes and 4 English capital letters (C, L, T, and H) target volumes were considered in this study. Two IMRT treatment plans were gene...

journal_title：Journal of cancer research and therapeutics

authors： Mandal A,Asthana AK,Pradhan S,Shahi UP,Choudhary S

更新日期：2019-01-01 00:00:00

abstract：AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...

journal_title：Journal of cancer research and therapeutics

authors： Yilmaz U,Yılmaz U,Yasar Z,Kıraklı EK,Ulger S,Ozdogan Y,Demirci NY,Erol S,Ozdogan I,Sahin B,Koksal D,Akcay C

更新日期：2016-01-01 00:00:00

abstract：Background:Conventional magnetic resonance imaging (MRI) does not accurately evaluate lymph node (LN) status, which is essential for the treatment and prognosis assessment in patients with rectal cancer. Objective:The aim of this study is to evaluate the diagnostic value of intravoxel incoherent motion (IVIM) MRI in d...

journal_title：Journal of cancer research and therapeutics

authors： Long L,Zhang H,He X,Zhou J,Guo D,Liu X

更新日期：2019-01-01 00:00:00

abstract：:Gardasil is the first quadrivalent human papillomavirus (HPV)-types 6, 11, 16, 18 recombinant vaccine approved by the FDA on June 8, 2006. It induces genotype-specific virus-neutralizing antibodies and prevents infection with HPV. Various clinical trials demonstrated a reduction in the incidence of vaccine-type-specif...

journal_title：Journal of cancer research and therapeutics

authors： Sharma R,Sharma CL

更新日期：2007-04-01 00:00:00

abstract：Aim of Study:Prostate cancer (PCa) is one of the most common cancers among men and has become a significant health problem in developing and developed countries. Prostate-specific antigen (PSA) is a useful marker for screening and monitoring the patients. In this study, the author aimed to detect the prevalence of PCa ...

journal_title：Journal of cancer research and therapeutics

authors： Çalışkan S

更新日期：2018-10-01 00:00:00

abstract：Introduction:Screening and diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and Ultrasonography/ ultrasound (USG) are individually effective diagnostic modalities for detection of breast pathologies...

journal_title：Journal of cancer research and therapeutics

authors： Tiwari P,Ghosh S,Agrawal VK

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Using physical wedges (PWs) to modify dose distribution and more homogeneous target coverage is a well-established technique. However, there are many problems with PWs known as beam hardening, which made them problematic. This can be overcome by dynamic wedges which do not filter beam. Comparison of physic...

journal_title：Journal of cancer research and therapeutics

authors： Geraily G,Sharafi N,Shirazi A,Esfehani M,Masoudifar M,Rajab BE

更新日期：2017-01-01 00:00:00

abstract：AIMS:To analyze the differences in dose distribution, with ovoid separation in various applications, by different radiotherapists in the same patient of carcinoma of the uterine cervix treated by multiple fractions of high-dose-rate (HDR) intracavitary Radio therapy (ICRT). SETTINGS:Pravara Rural Hospital and Rural Me...

journal_title：Journal of cancer research and therapeutics

authors： Jain VS,Singh KK,Umberkar RB,Sarje MB,Jain SM

更新日期：2010-04-01 00:00:00

abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare condition of ectopic calcification leading to increasing disability throughout life, with most patients being wheelchair bound by the age of 30. Ectopic calcification can be triggered by trauma and it is therefore important to minimize biopsies and operative proced...

journal_title：Journal of cancer research and therapeutics

authors： Frew JA,Kelly CG

更新日期：2008-01-01 00:00:00

abstract：:Camrelizumab is a programmed death receptor-1 inhibitor originally developed in China for the treatment of refractory lymphoma. It has also been effective in non-small-cell lung cancer patients. However, the rechallenge of camrelizumab was not reported previously. We report the rechallenge of camrelizumab therapy in t...

journal_title：Journal of cancer research and therapeutics

authors： Wei Z,Yang X,Ye X

更新日期：2020-09-01 00:00:00

abstract：CONTEXT:The diagnosis of malignant and potentially malignant epithelial lesions of oral mucosa cannot be based solely on clinical findings. The histologic evaluation of a representative biopsy specimen thus becomes necessary. The site for biopsy, however, is always a subjective choice that sometimes raises doubts about...

journal_title：Journal of cancer research and therapeutics

authors： Nayyar AS,Khan M,Bafna UD,Ahmed S,Chaluvaiah GH

更新日期：2014-07-01 00:00:00

abstract：Aims:Platinum-based chemotherapy is considered as the first-line treatment for nonsmall cell lung cancer (NSCLC) patients. However, platinum resistance and toxicity are major obstacles to its clinical applications. The two P-type ATPases ATP7A and ATP7B have been identified to play an essential role in the transport of...

journal_title：Journal of cancer research and therapeutics

authors： Li YQ,Zhang XY,Chen J,Yin JY,Li XP

更新日期：2018-01-01 00:00:00

abstract：Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...

journal_title：Journal of cancer research and therapeutics

authors： Bahadir A,Eral G,Budak M,Shimamoto F,Korpinar MA,Erdamar S,Tuncel H

更新日期：2019-01-01 00:00:00

abstract：:Rectal cancers may rarely metastasize in bone and when it occurs, is usually preceded by lung and/or liver metastasis. However, whether it may ever bypasses other organs, particularly lung and liver and metastasizes directly to bone or not, is debatable. Some authors have described the presence of isolated bone metast...

journal_title：Journal of cancer research and therapeutics

authors： Aich RK,Suman G,Phalguni G,Jibak B,Diptimoy D

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Tobacco use has been associated with various carcinomas including lung, esophagus, larynx, mouth, throat, kidney, bladder, pancreas, stomach, and cervix. Biomarkers such as concentration of cotinine in the blood, urine, or saliva have been used as objective measures to distinguish nonusers and users of tobac...

journal_title：Journal of cancer research and therapeutics

authors： Balhara YP,Jain R

更新日期：2013-01-01 00:00:00

abstract：:Hodgkin's lymphoma of the breast is very rare. We report a case of Hodgkin's lymphoma of the breast in a 61 year old post-menopausal female who presented with a 3 month history of left breast painless lump. Excision biopsy was done and histology showed nodular sclerotic Hodgkin's lymphoma confirmed by immunohistochemi...

journal_title：Journal of cancer research and therapeutics

authors： Osuji CU,Ahaneku GI,Onwubuya EI,Okocha EC,Ukah C,Emegoakor CD,Omejua EG

更新日期：2013-07-01 00:00:00

abstract：AIM:The discipline of radiotherapy (RT) in India is considered a low priority subject. Postgraduate (PG) students rarely choose RT as a career option. The possible reasons could be: 1) limited availability of PG course training centers, 2) limited job prospects, etc. We decided to conduct a survey of undergraduate (UG)...

journal_title：Journal of cancer research and therapeutics

authors： Sharma DN,Rath GK,Parashar A,Singh P

更新日期：2010-01-01 00:00:00

abstract：AIM OF STUDY:The present work aimed to examine the efficacy of two ayurvedic formulations, Brahma Rasayana (BRM) and Chyavanaprash (CHM) to alleviate doxorubicin (DOX) induced acute cardiotoxicity. MATERIALS AND METHODS:Swiss albino mice were administered with DOX (25 mg/kg, i.p.) and two doses of BRM or CHM (1 and 2 ...

journal_title：Journal of cancer research and therapeutics

authors： AlSuhailbani E,Menon A,Nair CK

更新日期：2016-04-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2016-07-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：:Hematological disorders, especially single lineage abnormalities, have been described in hyperthyroidism. Pancytopenia has been reported, without myelodysplastic syndrome or megaloblastic anemia. We studied the peripheral blood smear and the bone marrow aspiration and biopsy of a 65-year-old lady, who presented with p...

journal_title：Journal of cancer research and therapeutics

authors： Akoum R,Michel S,Wafic T,Emile B,Marwan M,Khaled H,Gerard A

更新日期：2007-01-01 00:00:00

abstract：Background:Several studies have investigated hypopharyngeal cancer (HC) risk in combination with xenobiotic metabolism-related genetic polymorphisms and the burden of alcohol consumption and smoking in European countries but not in East Asian countries. Patients and Methods:This hospital-based case-control study invol...

journal_title：Journal of cancer research and therapeutics

authors： Yamashita Y,Ikegami T,Suzuki M,Hirakawa H,Maeda H,Yamada S,Deng Z,Kondo S,Kinjyo H,Kiyuna A,Agena S,Uehara T,Ganaha A

更新日期：2019-07-01 00:00:00

abstract：Background and Objectives:Human chorionic gonadotropin-β (hCGβ) is a hormone glycoprotein usually secreted by trophoblastic cells in early pregnancy and helps in growth and development of the embryo. While many trophoblastic and nontrophoblastic malignancies express elevated levels of hCGβ in serum, increased immunohis...

journal_title：Journal of cancer research and therapeutics

authors： Meda S,Reginald BA,Reddy BS

更新日期：2018-07-01 00:00:00

abstract：AIM OF STUDY:Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. Recently, genome-wide association studies have identified two single nucleotide polymorphisms (SNP) associated with CRC in Caucasians. MATERIALS AND METHODS:To validate whether the same variation...

journal_title：Journal of cancer research and therapeutics

authors： Qiao HP,Zhang CY,Yu ZL,Li QM,Jiao Y,Cao JP

更新日期：2015-04-01 00:00:00

abstract：Objective:Conflicting data have been reported regarding the association between perioperative blood transfusion (PBT) and clinical outcomes for prostate cancer patients. We conducted a systematic review and meta-analysis to evaluate the impact of PBT on cancer survival and recurrence for patients who underwent radical ...

journal_title：Journal of cancer research and therapeutics

authors： Pushan Z,Manbiao C,Sulai L,Jun L,Ruidong Z,Hanshen Y

更新日期：2018-09-01 00:00:00