Abstract：
Aim of Study:Metabolic syndrome (MetS) is an abnormality that increases the risk of cardiovascular disease and diabetes. In the recent years, studies showed that MetS is associated with increased risk of incidence, aggressiveness, and mortality of prostate cancer (PCa). We examined the influence of MetS at final pathology in Turkish patients with PCa. Materials and Methods:MetS was defined according to the American Heart Association, National Heart, Lung, Blood Institute, and International Diabetes Federation and requires any three of five components. The patients without and with MetS were in Group 1 and 2, respectively. Data were compared with independent sample t-test and Chi-squared test. Results:There were 117 patients in the study. The patients' age was between 51 and 77 years with a median of 64.87 ± 5.65 and 62.29 ± 5.57, and prostate-specific antigen (PSA) level of the patients was 8.19 ± 5.35 and 8.68 ± 2.22 ng/ml in Group 1 and 2. Of these patients; Group 1 and 2 had 86 and 31 patients. High-grade PCa (Gleason >7) and advanced PCa (T3, T4) at final pathology were reported in 44.18-18.60% and 38.70-32.25% in Group 1 and 2. Conclusion:The patients with MetS are diagnosed significantly younger and had higher PSA levels than the other patients. Advanced disease of PCa is seen much more in patients with MetS.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Caliskan S,Kaba S,Özsoy E,Keleş MO,Koca O,Akyüz M,Karaman MIdoi
10.4103/0973-1482.187290subject
Has Abstractpub_date
2019-03-01 00:00:00pages
S47-S50issue
Supplementeissn
0973-1482issn
1998-4138pii
JCanResTher_2019_15_8_47_187290journal_volume
15pub_type
杂志文章abstract：BACKGROUND:Exfoliative cytology is an easy, economical, noninvasive, and feasible method for early detection and screening program of any premalignant or malignant lesion. In case of routine cytological procedure, classical Papanicolaou (PAP) stain is widely used while Romanowsky stains are sparingly used. Leishman-Gie...
journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章,评审
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journal_title：Journal of cancer research and therapeutics
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journal_title：Journal of cancer research and therapeutics
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