Abstract:
:Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Tyrosine kinase inhibitors (TKIs), such as imatinibmesylate, have been used for the adjuvant treatment of KIT-positive GISTs. Several pathologic changes after imatinib treatment of metastatic GIST including tumor necrosis, myxohyaline or sclerohyalinestroma, proliferative index decline, a varying degree of hemorrhage, edema, and cystic change have been reported in previous studies. More specifically, cystic changes after imatinib treatment were mainly induced by necrosis, hemorrhage, and degeneration. Until now, there have been no reports of cystic changes due to a dilated bile duct entrapped by a totally regressed tumor. We report a case of a 61-year-old man who was diagnosed with high-risk GIST of the stomach complicated by hepatic metastasis and who had such a unique pathologic changes with imatinib treatment.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Lee YS,Lee SH,Choi YJ,Jung ESdoi
10.4103/0973-1482.136030subject
Has Abstractpub_date
2014-07-01 00:00:00pages
763-6issue
3eissn
0973-1482issn
1998-4138pii
JCanResTher_2014_10_3_763_136030journal_volume
10pub_type
信件,评审abstract::[This corrects the article DOI: 10.4103/0973-1482.180685]. ...
journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of cancer research and therapeutics
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