Hypofractionated radiotherapy in carcinoma breast: What we have achieved?

abstract：Aim:Tumor-associated macrophages (TAMs) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis, and immune functions within tumor microenvironments. Tumor progression is frequently associated with a phenotypic switch from M1 to M2 in TAM. Activation of signal transdu...

journal_title：Journal of cancer research and therapeutics

authors： Seyedi Z,Hashemzadeh MR,Colagar AH,Jaafari MR

更新日期：2018-07-01 00:00:00

abstract：:Lymphoma of the salivary gland accounts for 5% of cases of extranodal lymphoma and 10% of malignant salivary gland tumors. Most primary salivary gland lymphomas are B marginal zone lymphomas arising on a background of sialadenitis associated with an autoimmune disorder such as Sjorgen's syndrome. This report describes...

journal_title：Journal of cancer research and therapeutics

authors： Metikurke SH,Krishnappa R,Ramachar SM,Arora I

更新日期：2012-10-01 00:00:00

abstract：:Choriocarcinoma is the most malignant tumor of gestational trophoblast origin. Metastasis to brain is considered a poor prognostic indicator. Recent advances in adjuvant radiotherapy and chemotherapy have led to an excellent outcome of these patients. Craniotomy is indicated in selected cases with cerebral metastases....

journal_title：Journal of cancer research and therapeutics

authors： Dadlani R,Furtado SV,Ghosal N,Prasanna KV,Hegde AS

更新日期：2010-10-01 00:00:00

abstract：AIM OF THE STUDY:In the present study the effects of mangiferin were tested against lung cancer-bearing mice in both the pre-initiation and post-initiation periods. MATERIALS AND METHODS:Healthy male Swiss albino mice (6-8 weeks old) were used throughout the study. The animals were treated with mangiferin (100 mg/kg b...

journal_title：Journal of cancer research and therapeutics

authors： Rajendran P,Rengarajan T,Nishigaki I,Ekambaram G,Sakthisekaran D

更新日期：2014-10-01 00:00:00

abstract：:The glucose analog 2-deoxy-D-glucose (2-DG), an inhibitor of glucose transport and glycolytic ATP production, is the most widely investigated metabolic inhibitor for targeting glucose metabolism. Besides depleting energy in cells, 2-DG has also been found to alter N-linked glycosylation leading to unfolded protein res...

journal_title：Journal of cancer research and therapeutics

authors： Dwarakanath BS

更新日期：2009-09-01 00:00:00

abstract：Aim:The aim of this study is to identify an ideal location of isocenter in intensity-modulated radiotherapy (IMRT) treatment plans. Materials and Methods:A total of 28 clinical target volumes and 4 English capital letters (C, L, T, and H) target volumes were considered in this study. Two IMRT treatment plans were gene...

journal_title：Journal of cancer research and therapeutics

authors： Mandal A,Asthana AK,Pradhan S,Shahi UP,Choudhary S

更新日期：2019-01-01 00:00:00

abstract：AIMS:To analyze the differences in dose distribution, with ovoid separation in various applications, by different radiotherapists in the same patient of carcinoma of the uterine cervix treated by multiple fractions of high-dose-rate (HDR) intracavitary Radio therapy (ICRT). SETTINGS:Pravara Rural Hospital and Rural Me...

journal_title：Journal of cancer research and therapeutics

authors： Jain VS,Singh KK,Umberkar RB,Sarje MB,Jain SM

更新日期：2010-04-01 00:00:00

abstract：:The management of patients with the clinically negative neck (N0) in early oral cancers awaits a clear mandate despite growing evidence favoring elective neck dissection. Having a general policy of operating all N0 neck may indeed increase the number of unnecessary neck dissection in the true pathological N0 necks, a ...

journal_title：Journal of cancer research and therapeutics

authors： Rao VU,Patil PH,Rajaram BV

更新日期：2016-07-01 00:00:00

abstract：:Rectal cancers may rarely metastasize in bone and when it occurs, is usually preceded by lung and/or liver metastasis. However, whether it may ever bypasses other organs, particularly lung and liver and metastasizes directly to bone or not, is debatable. Some authors have described the presence of isolated bone metast...

journal_title：Journal of cancer research and therapeutics

authors： Aich RK,Suman G,Phalguni G,Jibak B,Diptimoy D

更新日期：2014-04-01 00:00:00

abstract：Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...

journal_title：Journal of cancer research and therapeutics

authors： Bahadir A,Eral G,Budak M,Shimamoto F,Korpinar MA,Erdamar S,Tuncel H

更新日期：2019-01-01 00:00:00

abstract：AIMS:Hereditary nonpolyposis colorectal cancer (HNPCC) is a subgroup of colorectal cancer (CRC) which should be differentiated because of the high risk for additional cancers and risk evaluation for other family members, especially for CRC. It is not practical to perform genetic testing for all CRC patients; therefore,...

journal_title：Journal of cancer research and therapeutics

authors： Kaya M,Basak F,Sisik A,Hasbahceci M,Bas G,Alimoglu O,Topal CS,Kir G

更新日期：2017-04-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) a member of the heat shock proteins (HSPs) family, is an adenosine triphosphate dependent molecular chaperone protein, which integrates multiple oncogenic pathways. Clinically, encouraging results have been demonstrated in melanoma, acute myeloid leukemia, castrate refractory prostate can...

journal_title：Journal of cancer research and therapeutics

authors： Routray S,Sunkavalli A,Swain N,Shankar AA

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

journal_title：Journal of cancer research and therapeutics

authors： Chen HH,Wang QY,Zhou SH

更新日期：2016-01-01 00:00:00

abstract：AIMS:Few studies have examined the clinical characteristics of patients with brain metastases from small-cell esophageal cancer. In this study, we review the clinical characteristics and outcomes in patients with brain metastases from small-cell esophageal cancer. PATIENTS AND METHODS:From August 2002 to August 2012, ...

journal_title：Journal of cancer research and therapeutics

authors： Feng W,Harada H,Zhang P,Mitsuya K,Zheng X,Yasui H,Nakasu Y,Chen M,Nishimura T

更新日期：2014-12-01 00:00:00

abstract：Purpose:We aimed to report the experience of intraoperative electron radiation therapy (IOERT) with Mobetron (Intraop Medical Incorporated, Santa Clara, CA, USA) as a partial breast irradiation (PBI) for patients with early-stage breast cancer and explanation of IOERT application and present early clinical and cosmetic...

journal_title：Journal of cancer research and therapeutics

authors： Avci GG,Güney Y,Küçükpilakci B,Çalikoğlu T,Gülçelik MA,Özaslan C

更新日期：2019-07-01 00:00:00

abstract：Objective:This study investigated the association between abnormal matrix metalloproteinase-9 (MMP-9) expression and bladder cancer (BC) development. Materials and Methods:In a retrospective analysis, this study used tissue samples derived from 92 patients pathologically diagnosed with BC (experimental group), who wer...

journal_title：Journal of cancer research and therapeutics

authors： Wu GJ,Bao JS,Yue ZJ,Zeng FC,Cen S,Tang ZY,Kang XL

更新日期：2018-01-01 00:00:00

abstract：Purpose:In low-density (LD) gel dosimeter, diffusive spin-spin relaxation rate (R2)-dispersion caused by susceptibility-induced internal gradient leads to a significant deviation in the measured R2 from the real value. In this study, the effect of induced internal gradient on R2 was visualized and quantified algebraica...

journal_title：Journal of cancer research and therapeutics

authors： Pak F,Vaezzadeh V,Eqlimi E,Mirheydari M

更新日期：2019-07-01 00:00:00

abstract：:Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

journal_title：Journal of cancer research and therapeutics

authors： Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

更新日期：2018-01-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：Objective:The aim of this study was to explore the clinical value of capsule endoscopy in the diagnosis of small intestine neoplastic lesions. Materials and Methods:A retrospective analysis was conducted on the clinical data of 108 patients who underwent capsule endoscopic examination in the Endoscopy Center of Xinxia...

journal_title：Journal of cancer research and therapeutics

authors： Li X,Gui Y,Shen F,Zhao CL,Yang Y,Han W

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To assess the efficacy of radiation in the treatment of juvenile nasopharyngeal angiofibroma (JNA). MATERIALS AND METHODS:Data were retrieved for JNA treated with radiotherapy from 1987-2012. The demographics, treatment and outcome data were recorded in predesigned proforma. RESULTS:Data of 32 patients were r...

journal_title：Journal of cancer research and therapeutics

authors： Mallick S,Benson R,Bhasker S,Mohanti BK

更新日期：2015-01-01 00:00:00

abstract：:Prostate cancer, one of the most common male malignancies with an increasing incidence in the recent years, requires the development of new methods of treatment. One of the most debated subjects is the tumor-associated macrophages (TAM). Although, the pathophysiological mechanisms are still a subject of intense resear...

journal_title：Journal of cancer research and therapeutics

authors： Nenu I,Gafencu GA,Popescu T,Kacso G

更新日期：2017-07-01 00:00:00

abstract：Aims:To explore the biological roles of alpha-fetoprotein (AFP), a tumor-associated antigen in human hepatocellular carcinoma (HCC). Materials and Methods:After knockdown of AFP in HepG2 cells by transfection of specific Stealth™ RNAi, the expression of AFP were detected by reverse transcription polymerase chain react...

journal_title：Journal of cancer research and therapeutics

authors： Yang X,Chen L,Liang Y,Si R,Jiang Z,Ma B,Gao P

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Oral cancer is the third most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Transformation of normal tissue to premalignant lesion and further to oral cancer results in alteration in glycolytic pathway and hence the lactate dehydrogenase levels. Therefore...

journal_title：Journal of cancer research and therapeutics

authors： Shetty SR,Chadha R,Babu S,Kumari S,Bhat S,Achalli S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...

journal_title：Journal of cancer research and therapeutics

authors： Dodiya HG,Brahmbhatt AP,Khatri PK,Kaushal AM,Vijay DG

更新日期：2015-07-01 00:00:00

abstract：:Papillary carcinoma is a well-differentiated type of thyroid carcinoma with very good overall prognosis. The commonest site of metastases is the lymph node, distant metastases being rare. We present a case of a 52-year-old male who presented with a solitary metastasis in the left para-sellar region and cavernous sinus...

journal_title：Journal of cancer research and therapeutics

authors： Chandarana MN,Epari S,Chaukar D,Moiyadi AV

更新日期：2012-07-01 00:00:00

abstract：:Complementary and alternative medicine (CAM) use among cancer patients is widely prevalent and often underreported. Advanced stage of disease is significantly associated with CAM use. The concurrent use of alternative medicines and chemotherapy drugs has the potential to lead to toxicities as well as altered therapeut...

journal_title：Journal of cancer research and therapeutics

authors： Gulia S,Gota V,Kumar SD,Gupta S

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To study the clinical results and prognostic factors of patients with glioblastoma multiforme (GBM) treated by postoperative radiation therapy (PORT) and concomitant temozolomide followed by adjuvant temozolomide. METHODS:From 2005 to 2008, 215 patients (median age 48 years) with GBM were treated with PORT p...

journal_title：Journal of cancer research and therapeutics

authors： Julka PK,Sharma DN,Mallick S,Gandhi AK,Joshi N,Rath GK

更新日期：2013-07-01 00:00:00

abstract：Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated ...

journal_title：Journal of cancer research and therapeutics

authors： Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari F

更新日期：2019-03-01 00:00:00

abstract：Context/Background:Tooth agenesis (excluding third molars) is a common congenital disorder that affects 2.2-10% of the general population. A number of different genes have been shown to be associated with cases of tooth agenesis including AXIN2, IRF6, FGFR1, MSX1, PAX9, and TGFA. Wingless/integration signaling gene, AX...

journal_title：Journal of cancer research and therapeutics

authors： Paranjyothi MV,Kumaraswamy KL,Begum LF,Manjunath K,Litha.,Basheer S

更新日期：2018-04-01 00:00:00