Abstract:
:Lymphoproliferative malignancies can involve both nodal- and extra-nodal tissues. The most common extranodal site involved is the gastrointestinal (GI) tract, and it is secondary to the widespread primary nodal disease. However, about 33% of non-Hodgkin's lymphoma primarily arise from tissues other than lymph nodes, spleen, or bone marrow, for example, GI tract, skin, or the central nervous system and are called primary extranodal lymphomas. The most common site of GI localization is stomach (50%-60%) followed by small bowel. Primary colonic lymphoma is seen only in 6% of GI lymphomas and up to 0.5%-1% of all colon malignancies. Hence, primary GI lymphoma is extremely rare, and primary colonic lymphoma is an even rarer occurrence. There is clearly a paucity of cases reported in literature resulting in unclear treatment protocol. Here, we report a case of a 51-year-old man who presented with abdominal pain, weight loss, and bright red blood per rectum. A colonoscopy revealed diffuse bleeding ulcers involving the entire colon. Pathology was consistent with primary diffuse large B-cell lymphoma arising from the colon. The patient was started on treatment with rituximab, cyclophosphamide, adriamycin, vincristine, and prednisone.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Modi V,Bajaj N,Lakkasani S,Shaaban HS,Guron Gdoi
10.4103/jcrt.JCRT_239_17subject
Has Abstractpub_date
2020-01-01 00:00:00pages
167-169issue
1eissn
0973-1482issn
1998-4138pii
JCanResTher_2020_16_1_167_277102journal_volume
16pub_type
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abstract::[This corrects the article DOI: 10.4103/0973-1482.180685]. ...
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