Solanum muricatum Ait. inhibits inflammation and cancer by modulating the immune system.

abstract：AIM:This study was aimed to assess the in vivo anti-tumoral potency of the novel 6-nitro-2-(3-chloropropyl)-1H-benz[de]isoquinoline-1,3-dione [Compound 1] that has earlier demonstrated excellent cytotoxicity in 15 out of 17 human tumor cell lines tested. MATERIALS AND METHODS:Two murine tumors namely Sarcoma-180 (S-18...

journal_title：Journal of cancer research and therapeutics

authors： Mukherjee A,Dutta S,Sanyal U

更新日期：2013-07-01 00:00:00

abstract：Background:Lung cancer is the leading cause of cancer-related deaths worldwide. The high resistance of this type of cancer to radiotherapy and chemotherapy is the greatest challenge for the complete eradication of cancer cells. Although the combination of chemotherapeutic agents has some promising results, severe side ...

journal_title：Journal of cancer research and therapeutics

authors： Kahkesh MH,Salehi Z,Najafi M,Ghobadi A,Izad M,Shirazi A

更新日期：2020-10-01 00:00:00

abstract：:Rectal cancers may rarely metastasize in bone and when it occurs, is usually preceded by lung and/or liver metastasis. However, whether it may ever bypasses other organs, particularly lung and liver and metastasizes directly to bone or not, is debatable. Some authors have described the presence of isolated bone metast...

journal_title：Journal of cancer research and therapeutics

authors： Aich RK,Suman G,Phalguni G,Jibak B,Diptimoy D

更新日期：2014-04-01 00:00:00

abstract：:Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...

journal_title：Journal of cancer research and therapeutics

authors： Valecha J,Ojha SS,Sharma A,Nilkanthe R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Prostate-specific membrane antigen (PSMA) is a widely used targeted molecule in prostate patients. The present research, attempts to support the hypothesis that PSMA expression in prostate cancer stem cell-like (CSC) cell populations may be correlated with nanog and other transcription factors in different s...

journal_title：Journal of cancer research and therapeutics

authors： Maria T,Panagiotis A,Marina C,Eleni K,Ioanna V,Georgia M,Ioannis P

更新日期：2014-01-01 00:00:00

abstract：Background:Colorectal cancer (CRC) is the second most diagnosed cancer often identified during the later stages of carcinogenesis. Orientin, a C-glycoside of luteolin, is well known for its versatile therapeutic action toward oxidative stress-induced cellular response may exert chemoprevention against CRC. Materials a...

journal_title：Journal of cancer research and therapeutics

authors： Thangaraj K,Natesan K,Settu K,Palani M,Govindarasu M,Subborayan V,Vaiyapuri M

更新日期：2018-10-01 00:00:00

abstract：Background:Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Materials and Methods:Kyoto E...

journal_title：Journal of cancer research and therapeutics

authors： Yu B,Li T,Chen J,Wang FQ,Fu JH,Liu SM,Wang Y,Zhang X,Yang HT

更新日期：2020-07-01 00:00:00

abstract：AIM OF STUDY:Embelin and celastrol, inhibitors of XIAP and NF-κB proteins respectively, have been derived from natural sources and shown anti-tumor activities against different cancer cell lines. Some interactions have recently been discovered between XIAP and NF-κB pathways, but the effects of these inhibitors in comb...

journal_title：Journal of cancer research and therapeutics

authors： Pazhang Y,Jaliani HZ,Imani M,Dariushnejad H

更新日期：2016-01-01 00:00:00

abstract：:Symptoms of nausea and vomiting can present a diagnostic challenge for physicians. In this article, we report a patient who was found to have synchronous presentation of an ependymoma and pancreatic cancer. This case illustrates some of the diagnostic challenges in patients with constitutional symptoms. Furthermore, i...

journal_title：Journal of cancer research and therapeutics

authors： Chowdhry VK,Carter DA,Shapiro A

更新日期：2013-10-01 00:00:00

abstract：Context:Colorectal cancers are frequent among cancers of gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial. Aims:In this study, we aimed to compare survival in surgically treated rectum and colon cancers and determine the factors affecting ...

journal_title：Journal of cancer research and therapeutics

authors： Kalcan S,Sisik A,Basak F,Hasbahceci M,Kilic A,Kosmaz K,Kivanc AE,Kudas I,Bas G,Alimoglu O

更新日期：2018-01-01 00:00:00

abstract：:Chondrosarcoma is the most common malignant tumor of the chest wall. Most patients present with painful progressive swelling in the anterior chest wall arising from the costochondrosternal junction. CT scan with intravenous contrast is the investigation of choice. Wide excision with adequate margins is the standard tr...

journal_title：Journal of cancer research and therapeutics

authors： Singhal A,Mahajan C,Hadi R,Awasthi NP

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Using physical wedges (PWs) to modify dose distribution and more homogeneous target coverage is a well-established technique. However, there are many problems with PWs known as beam hardening, which made them problematic. This can be overcome by dynamic wedges which do not filter beam. Comparison of physic...

journal_title：Journal of cancer research and therapeutics

authors： Geraily G,Sharafi N,Shirazi A,Esfehani M,Masoudifar M,Rajab BE

更新日期：2017-01-01 00:00:00

abstract：Objective:The aim of good management for cancer survivors should not be limited to only clinical care, but rather it should also include best quality of life (QOL). The objective of this study was to find out various factors affecting QOL in cervical cancer patients so that by modifying these factors, the best QOL can ...

journal_title：Journal of cancer research and therapeutics

authors： Singh U,Verma ML,Rahman Z,Qureshi S,Srivastava K

更新日期：2019-10-01 00:00:00

abstract：:Small fields are more repeatedly used for radiation therapy as small segments in intensity-modulated radiotherapy or as in the form of independent fields in stereotactic radiosurgery and other novel equipment such as cyberknife and tomotherapy. Nevertheless, the application of small fields for radiotherapy of lung mak...

journal_title：Journal of cancer research and therapeutics

authors： Bagheri H,Soleimani A,Gharehaghaji N,Mesbahi A,Manouchehri F,Shekarchi B,Dormanesh B,Dadgar HA

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...

journal_title：Journal of cancer research and therapeutics

authors： Ahmed I,Ferro A,Baby R,Malhotra J,Cohler A,Langenfeld J,Aisner J,Zou W,Jabbour SK

更新日期：2016-04-01 00:00:00

abstract：AIM:To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). MATERIALS AND METHODS:We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. RESULTS:Age at presentation varied from...

journal_title：Journal of cancer research and therapeutics

authors： Mulay K,Ali MJ,Honavar SG,Reddy VA

更新日期：2014-04-01 00:00:00

abstract：Aim of Study:Association of toll-like receptors (TLRs) with the risk of oral squamous cell carcinoma (OSCC) from the published reports is still conflicting. This study was conducted to evaluate the relationship between TLRs and the risk of OSCC using meta-analysis method. Materials and Methods:The association studies ...

journal_title：Journal of cancer research and therapeutics

authors： Fang SL,Kong XB,Zhang ZQ

更新日期：2018-01-01 00:00:00

abstract：:Invasive papillary carcinoma of the breast is a rare, distinct variant comprising approximately less than 1-2% of all newly diagnosed cases of breast carcinoma and is usually found in postmenopausal women with a more favorable prognosis. We report an unusual case in a 45-year-old perimenopausal female who came with a ...

journal_title：Journal of cancer research and therapeutics

authors： Vani D,Geetanjali S,Punja GM,Bharathi M

更新日期：2015-10-01 00:00:00

abstract：Objective:This study investigated the association between abnormal matrix metalloproteinase-9 (MMP-9) expression and bladder cancer (BC) development. Materials and Methods:In a retrospective analysis, this study used tissue samples derived from 92 patients pathologically diagnosed with BC (experimental group), who wer...

journal_title：Journal of cancer research and therapeutics

authors： Wu GJ,Bao JS,Yue ZJ,Zeng FC,Cen S,Tang ZY,Kang XL

更新日期：2018-01-01 00:00:00

abstract：AIMS:Few studies have examined the clinical characteristics of patients with brain metastases from small-cell esophageal cancer. In this study, we review the clinical characteristics and outcomes in patients with brain metastases from small-cell esophageal cancer. PATIENTS AND METHODS:From August 2002 to August 2012, ...

journal_title：Journal of cancer research and therapeutics

authors： Feng W,Harada H,Zhang P,Mitsuya K,Zheng X,Yasui H,Nakasu Y,Chen M,Nishimura T

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:This study aims to explore the application of Choi's typing method in the immunological typing of diffuse large B-cell lymphoma (DLBCL) in Xinjiang Autonomous Region and its prognostic significance. MATERIALS AND METHODS:Seventy-eight cases of DLBCL tumor tissues from Xinjiang were collected to detect the ex...

journal_title：Journal of cancer research and therapeutics

authors： Jia CD,Liang LP,Yang LL,Yue N,Zhao F,Bai JP

更新日期：2015-10-01 00:00:00

abstract：Purpose:We aimed to report the experience of intraoperative electron radiation therapy (IOERT) with Mobetron (Intraop Medical Incorporated, Santa Clara, CA, USA) as a partial breast irradiation (PBI) for patients with early-stage breast cancer and explanation of IOERT application and present early clinical and cosmetic...

journal_title：Journal of cancer research and therapeutics

authors： Avci GG,Güney Y,Küçükpilakci B,Çalikoğlu T,Gülçelik MA,Özaslan C

更新日期：2019-07-01 00:00:00

abstract：Background:Apatinib has been approved for the treatment of advanced gastric adenocarcinoma and gastric-esophageal junctional adenocarcinoma, but its efficacy is unknown for other advanced solid tumors. Aims and Objectives:We retrospectively reviewed the use of apatinib for multiple advanced-stage non-gastric cancers. ...

journal_title：Journal of cancer research and therapeutics

authors： Wu X,Wang H,Wu Y,Jin J,Zhan Y,Zhu G,Zhang F,Zhang C,Gan J,Li W

更新日期：2019-01-01 00:00:00

abstract：Purpose:The aim of this study was to classify bilateral breast cancers (BBCs) into two groups according to histopathological or molecular subtypes of the two breast diseases in each patient and to study their characteristics in relation to survival outcomes. Methods:Fifty-six BBC patients were enrolled in the study. T...

journal_title：Journal of cancer research and therapeutics

authors： Wang Y,Du C,Tu L,Luo F,Yan X

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The integrity of the immune system is necessary to control tumor progression and a compromised state contributes to tumor escape. AIMS:The study intends to evaluate the presence and distribution pattern of Langerhans cells (LC) in Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) oral ...

journal_title：Journal of cancer research and therapeutics

authors： Upadhyay J,Rao NN,Upadhyay RB

更新日期：2012-10-01 00:00:00

abstract：:Lymphoproliferative malignancies can involve both nodal- and extra-nodal tissues. The most common extranodal site involved is the gastrointestinal (GI) tract, and it is secondary to the widespread primary nodal disease. However, about 33% of non-Hodgkin's lymphoma primarily arise from tissues other than lymph nodes, s...

journal_title：Journal of cancer research and therapeutics

authors： Modi V,Bajaj N,Lakkasani S,Shaaban HS,Guron G

更新日期：2020-01-01 00:00:00

abstract：Background and Objectives:Human chorionic gonadotropin-β (hCGβ) is a hormone glycoprotein usually secreted by trophoblastic cells in early pregnancy and helps in growth and development of the embryo. While many trophoblastic and nontrophoblastic malignancies express elevated levels of hCGβ in serum, increased immunohis...

journal_title：Journal of cancer research and therapeutics

authors： Meda S,Reginald BA,Reddy BS

更新日期：2018-07-01 00:00:00

abstract：:Chordoid meningioma (CM), classified as Grade II/atypical meningioma according to the World Health Organization classification, is a rare subtype, which represents only 0.5% of all meningiomas. Morphologically, it can mimic other chondroid and myxoid tumors within the brain and its vicinity thus posing a diagnostic ch...

journal_title：Journal of cancer research and therapeutics

authors： Siraj F,Ansari MK,Sharma KC,Singh A

更新日期：2015-07-01 00:00:00

abstract：:Primary vascular leiomyosarcoma (LMS) is a rare tumor accounting for 2% of all LMSs, with the most common site being inferior vena cava (IVC). Overall prognosis is poor, with median survival of 2 years only. We present four cases diagnosed with LMS of IVC, treated with surgery, radiation and chemotherapy. The diagnosi...

journal_title：Journal of cancer research and therapeutics

authors： Kapoor R,Bansal A,Sharma SC

更新日期：2015-07-01 00:00:00

abstract：:A 29-year-old hypertensive male with von Hippel-Lindau (VHL) syndrome came to the Endocrinology department for evaluation. Contrast-enhanced computed tomography of the abdomen revealed an adrenal mass, bilateral renal cell carcinoma, and multiple pancreatic cysts. The hormonal investigations for adrenal mass were norm...

journal_title：Journal of cancer research and therapeutics

authors： Palui R,Kamalanathan S,Sahoo J,Dorairajan LN,Badhe B,Gochhait D

更新日期：2019-03-01 00:00:00