Abstract:
:An erythroid-specific enhancer was previously identified in the 3'-flanking region of the beta adult gene in chicken and duck, by transfection into AEV transformed chicken erythroblasts. Here we show that the duck enhancer is equally active in erythroid human K562 cells, presenting an embryonic/fetal program of globin gene expression. Furthermore, no other enhancer was found within the 20 kb of DNA including four beta-like globin genes as well as a 1.5 kb upstream and a 3 kb downstream sequence.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Kretsovali A,Marcaud L,Huesca M,Scherrer Kdoi
10.1016/0014-5793(88)80103-0subject
Has Abstractpub_date
1988-07-18 00:00:00pages
300-4issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(88)80103-0journal_volume
234pub_type
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