Abstract:
:AtCYP20-2 is one of 16 immunophilins in thylakoid lumen. The presence of the isomerase domain in AtCYP20-2, an enrichment of AtCYP20-2 in the stroma membranes and it's co-migration with NAD(P)H dehydrogenase (NDH) in native gels provide evidence that AtCYP20-2 is an auxiliary protein of NDH. When different NDH mutants were studied, AtCYP20-2 was found to be strongly reduced especially in mutants deficient in the membrane domain of NDH, thus suggesting a role in the assembly of NDH hydrophobic domain. Lack of AtCYP20-2, however, did not lead to severe malfunction of NDH, indicating redundancy in the function of lumenal immunophilins.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Sirpiö S,Holmström M,Battchikova N,Aro EMdoi
10.1016/j.febslet.2009.06.031subject
Has Abstractpub_date
2009-07-21 00:00:00pages
2355-8issue
14eissn
0014-5793issn
1873-3468pii
S0014-5793(09)00486-4journal_volume
583pub_type
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