The Par3 polarity protein is an exocyst receptor essential for mammary cell survival.

abstract：:Long-term follow up studies from Ebola virus disease (EVD) survivors (EBOV_S) are lacking. Here, we evaluate immune and gene expression profiles in 35 Guinean EBOV_S from the last West African outbreak, a median of 23 months (IQR [18-25]) after discharge from treatment center. Compared with healthy donors, EBOV_S exhi...

journal_title：Nature communications

authors： Wiedemann A,Foucat E,Hocini H,Lefebvre C,Hejblum BP,Durand M,Krüger M,Keita AK,Ayouba A,Mély S,Fernandez JC,Touré A,Fourati S,Lévy-Marchal C,Raoul H,Delaporte E,Koivogui L,Thiébaut R,Lacabaratz C,Lévy Y,PostEboGui

更新日期：2020-07-24 00:00:00

abstract：:Pattern-triggered immunity and effector-triggered immunity are two primary forms of innate immunity in land plants. The molecular components and connecting nodes of pattern-triggered immunity and effector-triggered immunity are not fully understood. Here, we report that the Arabidopsis calcium-dependent protein kinase...

journal_title：Nature communications

authors： Lu YJ,Li P,Shimono M,Corrion A,Higaki T,He SY,Day B

更新日期：2020-12-04 00:00:00

abstract：:Calcareous microplankton shells form the dominant components of ancient and modern pelagic sea-floor carbonates and are widely used in palaeoenvironmental reconstructions. The efficacy of these applications, however, is dependent upon minimal geochemical alteration during diagenesis, but these modifying processes are ...

journal_title：Nature communications

authors： Wendler JE,Bown P

更新日期：2013-01-01 00:00:00

abstract：:Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a single human tumour xeno...

journal_title：Nature communications

authors： Nguyen LV,Cox CL,Eirew P,Knapp DJ,Pellacani D,Kannan N,Carles A,Moksa M,Balani S,Shah S,Hirst M,Aparicio S,Eaves CJ

更新日期：2014-12-23 00:00:00

abstract：:Topological insulators represent a new quantum state of matter that are insulating in the bulk but metallic on the edge or surface. In the Dirac surface state, it is well-established that the electron spin is locked with the crystal momentum. Here we report a new phenomenon of the spin texture locking with the orbital...

journal_title：Nature communications

authors： Xie Z,He S,Chen C,Feng Y,Yi H,Liang A,Zhao L,Mou D,He J,Peng Y,Liu X,Liu Y,Liu G,Dong X,Yu L,Zhang J,Zhang S,Wang Z,Zhang F,Yang F,Peng Q,Wang X,Chen C,Xu Z,Zhou XJ

更新日期：2014-02-28 00:00:00

abstract：:The mathematics of gauge theories lies behind many of the most profound advances in physics in the past 200 years, from Maxwell's theory of electromagnetism to Einstein's theory of general relativity. More recently it has become clear that gauge theories also emerge in condensed matter, a prime example being the spin-...

journal_title：Nature communications

authors： Benton O,Jaubert LD,Yan H,Shannon N

更新日期：2016-05-26 00:00:00

abstract：:Quantized dynamics is essential for natural processes and technological applications alike. The work of Thouless on quantized particle transport in slowly varying potentials (Thouless pumping) has played a key role in understanding that such quantization may be caused not only by discrete eigenvalues of a quantum syst...

journal_title：Nature communications

authors： Fedorova Z,Qiu H,Linden S,Kroha J

更新日期：2020-07-27 00:00:00

abstract：:Light-phase-sensitive techniques, such as coherent multidimensional spectroscopy, are well-established in a broad spectral range, already spanning from radio-frequencies in nuclear magnetic resonance spectroscopy to visible and ultraviolet wavelengths in nonlinear optics with table-top lasers. In these cases, the abil...

journal_title：Nature communications

authors： Usenko S,Przystawik A,Jakob MA,Lazzarino LL,Brenner G,Toleikis S,Haunhorst C,Kip D,Laarmann T

更新日期：2017-05-30 00:00:00

abstract：:The mammalian neocortex is subdivided into cytoarchitectural areas with distinct connectivity, gene expression and neural functions. Areal identity is initially specified by rostrocaudal and mediolateral gene expression gradients in neuroepithelial and radial glial progenitors (the 'protomap'). On further differentiat...

journal_title：Nature communications

authors： Alfano C,Magrinelli E,Harb K,Hevner RF,Studer M

更新日期：2014-12-05 00:00:00

abstract：:While plasmonic designs have dominated recent trends in structural color, schemes using localized surface plasmon resonances and surface plasmon polaritons that simultaneously achieve high color vibrancy at ultrahigh resolution have been elusive because of tradeoffs between size and performance. Herein we demonstrate ...

journal_title：Nature communications

authors： Lee JS,Park JY,Kim YH,Jeon S,Ouellette O,Sargent EH,Kim DH,Hyun JK

更新日期：2019-10-21 00:00:00

abstract：:RNA sequencing (RNA-seq) is the leading technology for genome-wide transcript quantification. However, publicly available RNA-seq data is currently provided mostly in raw form, a significant barrier for global and integrative retrospective analyses. ARCHS4 is a web resource that makes the majority of published RNA-seq...

journal_title：Nature communications

authors： Lachmann A,Torre D,Keenan AB,Jagodnik KM,Lee HJ,Wang L,Silverstein MC,Ma'ayan A

更新日期：2018-04-10 00:00:00

abstract：:Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable for a substantial fraction of microbial species, introduces estimation biases. We ...

journal_title：Nature communications

authors： Milanese A,Mende DR,Paoli L,Salazar G,Ruscheweyh HJ,Cuenca M,Hingamp P,Alves R,Costea PI,Coelho LP,Schmidt TSB,Almeida A,Mitchell AL,Finn RD,Huerta-Cepas J,Bork P,Zeller G,Sunagawa S

更新日期：2019-03-04 00:00:00

abstract：:Hypertensive disorders in pregnancy (HDPs) are leading perinatal diseases. Using a national cohort of 2,043,182 pregnant women in China, we evaluated the association between ambient temperatures and HDP subgroups, including preeclampsia or eclampsia, gestational hypertension, and superimposed preeclampsia. Under extre...

journal_title：Nature communications

authors： Xiong T,Chen P,Mu Y,Li X,Di B,Li J,Qu Y,Tang J,Liang J,Mu D

更新日期：2020-06-10 00:00:00

abstract：:Ductal occlusion has been postulated to precipitate focal pancreatic inflammation, while the nature of the primary occluding agents has remained elusive. Neutrophils make use of histone citrullination by peptidyl arginine deiminase-4 (PADI4) in contact to particulate agents to extrude decondensed chromatin as neutroph...

journal_title：Nature communications

authors： Leppkes M,Maueröder C,Hirth S,Nowecki S,Günther C,Billmeier U,Paulus S,Biermann M,Munoz LE,Hoffmann M,Wildner D,Croxford AL,Waisman A,Mowen K,Jenne DE,Krenn V,Mayerle J,Lerch MM,Schett G,Wirtz S,Neurath MF,Herrm

更新日期：2016-03-11 00:00:00

abstract：:Fibroblastic reticular cells (FRCs) are immunologically specialized myofibroblasts of lymphoid organ, and FRC maturation is essential for structural and functional properties of lymph nodes (LNs). Here we show that YAP and TAZ (YAP/TAZ), the final effectors of Hippo signaling, regulate FRC commitment and maturation. S...

journal_title：Nature communications

authors： Choi SY,Bae H,Jeong SH,Park I,Cho H,Hong SP,Lee DH,Lee CK,Park JS,Suh SH,Choi J,Yang MJ,Jang JY,Onder L,Moon JH,Jeong HS,Adams RH,Kim JM,Ludewig B,Song JH,Lim DS,Koh GY

更新日期：2020-01-24 00:00:00

abstract：:The development of high efficiency solar cells relies on the management of electronic and optical properties that need to be accurately measured. As the conversion efficiencies increase, there is a concomitant electronic and photonic contribution that affects the overall performances. Here we show an optical method to...

journal_title：Nature communications

authors： Bercegol A,Ory D,Suchet D,Cacovich S,Fournier O,Rousset J,Lombez L

更新日期：2019-04-08 00:00:00

abstract：:Between the land and ocean, diverse coastal ecosystems transform, store, and transport material. Across these interfaces, the dynamic exchange of energy and matter is driven by hydrological and hydrodynamic processes such as river and groundwater discharge, tides, waves, and storms. These dynamics regulate ecosystem f...

journal_title：Nature communications

authors： Ward ND,Megonigal JP,Bond-Lamberty B,Bailey VL,Butman D,Canuel EA,Diefenderfer H,Ganju NK,Goñi MA,Graham EB,Hopkinson CS,Khangaonkar T,Langley JA,McDowell NG,Myers-Pigg AN,Neumann RB,Osburn CL,Price RM,Rowland J,Sen

更新日期：2020-05-18 00:00:00

abstract：:Recent studies of thermal transport in nanomaterials have demonstrated the breakdown of Fourier's law through observations of ballistic transport. Despite its unique features, another instance of the breakdown of Fourier's law, hydrodynamic phonon transport, has drawn less attention because it has been observed only a...

journal_title：Nature communications

authors： Lee S,Broido D,Esfarjani K,Chen G

更新日期：2015-02-18 00:00:00

abstract：:Artificially improving traits of cultivated alfalfa (Medicago sativa L.), one of the most important forage crops, is challenging due to the lack of a reference genome and an efficient genome editing protocol, which mainly result from its autotetraploidy and self-incompatibility. Here, we generate an allele-aware chrom...

journal_title：Nature communications

authors： Chen H,Zeng Y,Yang Y,Huang L,Tang B,Zhang H,Hao F,Liu W,Li Y,Liu Y,Zhang X,Zhang R,Zhang Y,Li Y,Wang K,He H,Wang Z,Fan G,Yang H,Bao A,Shang Z,Chen J,Wang W,Qiu Q

更新日期：2020-05-19 00:00:00

abstract：:Microbial fatty acid-derived fuels have emerged as promising alternatives to petroleum-based transportation fuels. Here we report a modular engineering approach that systematically removed metabolic pathway bottlenecks and led to significant titre improvements in a multi-gene fatty acid metabolic pathway. On the basis...

journal_title：Nature communications

authors： Xu P,Gu Q,Wang W,Wong L,Bower AG,Collins CH,Koffas MA

更新日期：2013-01-01 00:00:00

abstract：:Previous research has focused on feeding circuits residing in the hindbrain and midbrain that govern homeostatic or hedonic control of food intake. However, the feeding circuits controlling emotional or cognitive aspects of food intake are largely unknown. Here we use chemical genetics and optogenetic techniques to di...

journal_title：Nature communications

authors： Sweeney P,Yang Y

更新日期：2015-12-15 00:00:00

abstract：:Recent studies demonstrated a dramatically increased risk of leukemia in patients with a rare genetic disorder, Xeroderma Pigmentosum group C (XP-C), characterized by constitutive deficiency of global genome nucleotide excision repair (GG-NER). The genetic mechanisms of non-skin cancers in XP-C patients remain unexplo...

journal_title：Nature communications

authors： Yurchenko AA,Padioleau I,Matkarimov BT,Soulier J,Sarasin A,Nikolaev S

更新日期：2020-11-17 00:00:00

abstract：:A non-syngas direct steam reforming route is investigated for the conversion of methanol to hydrogen and carbon dioxide over a CuZnGaO(x) catalyst at 150-200 °C. This route is in marked contrast with the conventional complex route involving steam reformation to syngas (CO/H2) at high temperature, followed by water gas...

journal_title：Nature communications

authors： Yu KM,Tong W,West A,Cheung K,Li T,Smith G,Guo Y,Tsang SC

更新日期：2012-01-01 00:00:00

abstract：:Protein integration into biological membranes is a vital cellular event for all organisms. We previously reported an integration factor in the inner membrane of Escherichia coli, named MPIase (membrane protein integrase). Here we show that in contrast to previously identified integration factors that are proteins, MPI...

journal_title：Nature communications

authors： Nishiyama K,Maeda M,Yanagisawa K,Nagase R,Komura H,Iwashita T,Yamagaki T,Kusumoto S,Tokuda H,Shimamoto K

更新日期：2012-01-01 00:00:00

abstract：:Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is key in elucidating biological mechanisms underlying socioeconomic disparities. Here we explore the relatio...

journal_title：Nature communications

authors： Berger E,Castagné R,Chadeau-Hyam M,Bochud M,d'Errico A,Gandini M,Karimi M,Kivimäki M,Krogh V,Marmot M,Panico S,Preisig M,Ricceri F,Sacerdote C,Steptoe A,Stringhini S,Tumino R,Vineis P,Delpierre C,Kelly-Irving M

更新日期：2019-02-15 00:00:00

abstract：:[This corrects the article DOI: 10.1038/ncomms5802.]. ...

journal_title：Nature communications

authors： Rakheja D,Chen KS,Liu Y,Shukla AA,Schmid V,Chang TC,Khokhar S,Wickiser JE,Karandikar NJ,Malter JS,Mendell JT,Amatruda JF

更新日期：2017-11-29 00:00:00

abstract：:Two-dimensional materials provide extraordinary opportunities for exploring phenomena arising in atomically thin crystals. Beginning with the first isolation of graphene, mechanical exfoliation has been a key to provide high-quality two-dimensional materials, but despite improvements it is still limited in yield, late...

journal_title：Nature communications

authors： Huang Y,Pan YH,Yang R,Bao LH,Meng L,Luo HL,Cai YQ,Liu GD,Zhao WJ,Zhou Z,Wu LM,Zhu ZL,Huang M,Liu LW,Liu L,Cheng P,Wu KH,Tian SB,Gu CZ,Shi YG,Guo YF,Cheng ZG,Hu JP,Zhao L,Yang GH,Sutter E,Sutter P,Wan

更新日期：2020-05-15 00:00:00

abstract：:Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper uptake via the induction of a metalloreductase, STEAP4. IL-17-induced ...

journal_title：Nature communications

authors： Liao Y,Zhao J,Bulek K,Tang F,Chen X,Cai G,Jia S,Fox PL,Huang E,Pizarro TT,Kalady MF,Jackson MW,Bao S,Sen GC,Stark GR,Chang CJ,Li X

更新日期：2020-02-14 00:00:00

abstract：:Ruddlesden-Popper halide perovskites are 2D solution-processed quantum wells with a general formula A2A'n-1M n X3n+1, where optoelectronic properties can be tuned by varying the perovskite layer thickness (n-value), and have recently emerged as efficient semiconductors with technologically relevant stability. However,...

journal_title：Nature communications

authors： Blancon JC,Stier AV,Tsai H,Nie W,Stoumpos CC,Traoré B,Pedesseau L,Kepenekian M,Katsutani F,Noe GT,Kono J,Tretiak S,Crooker SA,Katan C,Kanatzidis MG,Crochet JJ,Even J,Mohite AD

更新日期：2018-06-08 00:00:00

abstract：:Making decisions based on choice-outcome history is a crucial, adaptive ability in life. However, the neural circuit mechanisms underlying history-dependent decision-making are poorly understood. In particular, history-related signals have been found in many brain areas during various decision-making tasks, but the ca...

journal_title：Nature communications

authors： Hwang EJ,Dahlen JE,Mukundan M,Komiyama T

更新日期：2017-11-01 00:00:00