Abstract:
:Hypertensive disorders in pregnancy (HDPs) are leading perinatal diseases. Using a national cohort of 2,043,182 pregnant women in China, we evaluated the association between ambient temperatures and HDP subgroups, including preeclampsia or eclampsia, gestational hypertension, and superimposed preeclampsia. Under extreme temperatures, very cold exposure during preconception (12 weeks) increases odds of preeclampsia or eclampsia and gestational hypertension. Compared to preconception, in the first half of pregnancy, the impact of temperature on preeclampsia or eclampsia and gestational hypertension is opposite. Cold exposure decreases the odds, whereas hot exposure increases the odds. Under average temperatures, a temperature increase during preconception decreases the risk of preeclampsia or eclampsia and gestational hypertension. However, in the first half of pregnancy, temperature is positively associated with a higher risk. No significant association is observed between temperature and superimposed preeclampsia. Here we report a close relationship exists between ambient temperature and preeclampsia or eclampsia and gestational hypertension.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Xiong T,Chen P,Mu Y,Li X,Di B,Li J,Qu Y,Tang J,Liang J,Mu Ddoi
10.1038/s41467-020-16775-8subject
Has Abstractpub_date
2020-06-10 00:00:00pages
2925issue
1issn
2041-1723pii
10.1038/s41467-020-16775-8journal_volume
11pub_type
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