Directional charge separation in isolated organic semiconductor crystalline nanowires.

abstract：:Cold- and β3-adrenoceptor agonist-induced sympathetic activation leads to angiogenesis and UCP1-dependent thermogenesis in mouse brown and white adipose tissues. Here we show that endothelial production of PDGF-CC during white adipose tissue (WAT) angiogenesis regulates WAT browning. We find that genetic deletion of e...

journal_title：Nature communications

authors： Seki T,Hosaka K,Lim S,Fischer C,Honek J,Yang Y,Andersson P,Nakamura M,Näslund E,Ylä-Herttuala S,Sun M,Iwamoto H,Li X,Liu Y,Samani NJ,Cao Y

更新日期：2016-08-05 00:00:00

abstract：:Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli. Here, we show that the d...

journal_title：Nature communications

authors： Dutertre S,Jin AH,Vetter I,Hamilton B,Sunagar K,Lavergne V,Dutertre V,Fry BG,Antunes A,Venter DJ,Alewood PF,Lewis RJ

更新日期：2014-03-24 00:00:00

abstract：:Puberty is regulated by epigenetic mechanisms and is highly sensitive to metabolic and nutritional cues. However, the epigenetic pathways mediating the effects of nutrition and obesity on pubertal timing are unknown. Here, we identify Sirtuin 1 (SIRT1), a fuel-sensing deacetylase, as a molecule that restrains female p...

journal_title：Nature communications

authors： Vazquez MJ,Toro CA,Castellano JM,Ruiz-Pino F,Roa J,Beiroa D,Heras V,Velasco I,Dieguez C,Pinilla L,Gaytan F,Nogueiras R,Bosch MA,Rønnekleiv OK,Lomniczi A,Ojeda SR,Tena-Sempere M

更新日期：2018-10-10 00:00:00

abstract：:Identifying a bona fide population of cardiac stem cells (CSCs) is a critical step for developing cell-based therapies for heart failure patients. Previously, cardiac c-kit(+) cells were reported to be CSCs with a potential to become myocardial, endothelial and smooth muscle cells in vitro and after cardiac injury. He...

journal_title：Nature communications

authors： Sultana N,Zhang L,Yan J,Chen J,Cai W,Razzaque S,Jeong D,Sheng W,Bu L,Xu M,Huang GY,Hajjar RJ,Zhou B,Moon A,Cai CL

更新日期：2015-10-30 00:00:00

abstract：:TP53 mutations are the most frequent genetic alterations in breast cancer and are associated with more aggressive disease and worse overall survival. We have created two conditional mutant Trp53 alleles in the mouse that allow expression of Trp53R172H or Trp53R245W missense mutations in single cells surrounded by a no...

journal_title：Nature communications

authors： Zhang Y,Xiong S,Liu B,Pant V,Celii F,Chau G,Elizondo-Fraire AC,Yang P,You MJ,El-Naggar AK,Navin NE,Lozano G

更新日期：2018-09-27 00:00:00

abstract：:Nature has developed striking light-powered proteins such as bacteriorhodopsin, which can convert light energy into conformational changes for biological functions. Such natural machines are a great source of inspiration for creation of their synthetic analogues. However, synthetic molecular machines typically operate...

journal_title：Nature communications

authors： Kuzyk A,Yang Y,Duan X,Stoll S,Govorov AO,Sugiyama H,Endo M,Liu N

更新日期：2016-02-02 00:00:00

abstract：:The gravitational collapse of eruption columns generates ground-hugging pyroclastic density currents (PDCs) with highly variable temperatures, high enough to be a threat for communities surrounding volcanoes. The reasons for such great temperature variability are debated in terms of eruptive versus transport and empla...

journal_title：Nature communications

authors： Trolese M,Cerminara M,Esposti Ongaro T,Giordano G

更新日期：2019-06-06 00:00:00

abstract：:The original version of this Article contained an error in Fig. 3. The scale bars in Figs 3c and 3d were incorrectly labelled as 50 μA. In the correct version, the scale bars are labelled as 0.5 μA. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Li X,Zhai T,Gao P,Cheng H,Hou R,Lou X,Xia F

更新日期：2018-02-08 00:00:00

abstract：:The history of the Earth has been marked by major ecological transitions, driven by metabolic innovation, that radically reshaped the composition of the oceans and atmosphere. The nature and magnitude of the earliest transitions, hundreds of million years before photosynthesis evolved, remain poorly understood. Using ...

journal_title：Nature communications

authors： Sauterey B,Charnay B,Affholder A,Mazevet S,Ferrière R

更新日期：2020-06-01 00:00:00

abstract：:The extent and importance of endogenous viral elements have been extensively described in animals but are much less well understood in plants. Here we describe a new genus of Caulimoviridae called 'Florendovirus', members of which have colonized the genomes of a large diversity of flowering plants, sometimes at very h...

journal_title：Nature communications

authors： Geering AD,Maumus F,Copetti D,Choisne N,Zwickl DJ,Zytnicki M,McTaggart AR,Scalabrin S,Vezzulli S,Wing RA,Quesneville H,Teycheney PY

更新日期：2014-11-10 00:00:00

abstract：:High-performance Li-ion batteries require materials with well-designed and controlled structures on nanometre and micrometre scales. Electrochemical properties can be enhanced by reducing crystallite size and by manipulating structure and morphology. Here we show a method for preparing hierarchically structured Li4Ti5...

journal_title：Nature communications

authors： Odziomek M,Chaput F,Rutkowska A,Świerczek K,Olszewska D,Sitarz M,Lerouge F,Parola S

更新日期：2017-05-26 00:00:00

abstract：:Myxofibrosarcoma (MFS) is a common adult soft tissue sarcoma characterized by an infiltrative growth pattern and a high local recurrence rate. Here we report the genetic and epigenetic landscape of MFS based on the results of whole-exome sequencing (N = 41), RNA sequencing (N = 29), and methylation analysis (N = 41), ...

journal_title：Nature communications

authors： Ogura K,Hosoda F,Arai Y,Nakamura H,Hama N,Totoki Y,Yoshida A,Nagai M,Kato M,Arakawa E,Mukai W,Rokutan H,Kawai A,Tanaka S,Shibata T

更新日期：2018-07-17 00:00:00

abstract：:The challenge of monitoring in planta dynamic changes of NADP(H) and NAD(H) redox states at the subcellular level is considered a major obstacle in plant bioenergetics studies. Here, we introduced two circularly permuted yellow fluorescent protein sensors, iNAP and SoNar, into Arabidopsis thaliana to monitor the dynam...

journal_title：Nature communications

authors： Lim SL,Voon CP,Guan X,Yang Y,Gardeström P,Lim BL

更新日期：2020-06-26 00:00:00

abstract：:The ability to modulate nanoparticle (NP) assemblies with atomic precision is still lacking, which hinders us from creating hierarchical NP organizations with desired properties. In this work, a hierarchical fibrous (1D to 3D) assembly of Au NPs (21-gold atom, Au21) is realized and further modulated with atomic precis...

journal_title：Nature communications

authors： Li Q,Russell JC,Luo TY,Roy X,Rosi NL,Zhu Y,Jin R

更新日期：2018-09-24 00:00:00

abstract：:Digital polymers with precisely ordered units acting as the coded 0- or 1-bit, are introduced as a promising option for molecular data storage. However, the pursuit of better performance in terms of high storage capacity and useful functions never stops. Herein, we propose a concept of an information-coded 2D digital ...

journal_title：Nature communications

authors： Huang Z,Shi Q,Guo J,Meng F,Zhang Y,Lu Y,Qian Z,Li X,Zhou N,Zhang Z,Zhu X

更新日期：2019-04-23 00:00:00

abstract：:While molecular water-oxidation catalysts are remarkably rapid, oxidative and hydrolytic processes in water can convert their active transition metals to colloidal metal oxides or hydroxides that, while quite reactive, are insoluble or susceptible to precipitation. In response, we propose using oxidatively-inert ligan...

journal_title：Nature communications

authors： Chakraborty B,Gan-Or G,Raula M,Gadot E,Weinstock IA

更新日期：2018-11-20 00:00:00

abstract：:Human-machine interfaces have benefited from the advent of wireless sensor networks and the internet of things, but rely on wearable/attachable electronics exhibiting stretchability, biocompatibility, and transmittance. Limited by weight and volume, wearable devices should be energy efficient and even self-powered. He...

journal_title：Nature communications

authors： Lee Y,Cha SH,Kim YW,Choi D,Sun JY

更新日期：2018-05-04 00:00:00

abstract：:The Dansgaard-Oeschger (DO) events, as observed in oxygen isotope ratios from the North Greenland Ice Core Project (NGRIP) record, are an outstanding example of past abrupt climate transitions. Their physical cause remains debated, and previous research indicated that they are not preceded by classical early-warning s...

journal_title：Nature communications

authors： Boers N

更新日期：2018-07-02 00:00:00

abstract：:Calcium ions (Ca(2+)) function as universal second messengers in eukaryotic cells, including immune cells. Ca(2+) is crucial for peripheral T-lymphocyte activation and effector functions, and influences thymocyte selection and motility in the developing thymus. However, the role of Ca(2+) signalling in early T-lymphoc...

journal_title：Nature communications

authors： Ouyang K,Leandro Gomez-Amaro R,Stachura DL,Tang H,Peng X,Fang X,Traver D,Evans SM,Chen J

更新日期：2014-09-12 00:00:00

abstract：:Inflammasomes regulate innate immune responses by facilitating maturation of inflammatory cytokines, interleukin (IL)-1β and IL-18. NACHT, LRR and PYD domains-containing protein 7 (NALP7) is one inflammasome constituent, but little is known about its cellular handling. Here we show a mechanism for NALP7 protein stabil...

journal_title：Nature communications

authors： Bednash JS,Weathington N,Londino J,Rojas M,Gulick DL,Fort R,Han S,McKelvey AC,Chen BB,Mallampalli RK

更新日期：2017-05-11 00:00:00

abstract：:The original version of the Supplementary Information associated with this Article contained errors in Supplementary Figures 2, 12, 20 and 22. The HTML has been updated to include a corrected version of the Supplementary Information; the original incorrect versions of these Figures can be found as Supplementary Inform...

journal_title：Nature communications

authors： Eberlein C,Hénault M,Fijarczyk A,Charron G,Bouvier M,Kohn LM,Anderson JB,Landry CR

更新日期：2019-05-13 00:00:00

abstract：:Imaging the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques requiring sophisticated noise rejection are available. Here we use signal enhancement i...

journal_title：Nature communications

authors： Mader M,Reichel J,Hänsch TW,Hunger D

更新日期：2015-06-24 00:00:00

abstract：:Hydroarylation is an environmentally attractive strategy which incorporates all of the atoms contained in the substrates into the desired products. Almost all the hydroarylations of norbornene reported to date involve an exo-selective reaction. Here we show the endo-selective hydroarylation of norbornene in the Rh(I)-...

journal_title：Nature communications

authors： Shibata K,Natsui S,Tobisu M,Fukumoto Y,Chatani N

更新日期：2017-11-13 00:00:00

abstract：:Predicting and controlling quantum mechanical phenomena require knowledge of the system Hamiltonian. A detailed understanding of the quantum pathways used to construct the Hamiltonian is essential for deterministic control and improved performance of coherent control schemes. In complex systems, parameters characteriz...

journal_title：Nature communications

authors： Li H,Bristow AD,Siemens ME,Moody G,Cundiff ST

更新日期：2013-01-01 00:00:00

abstract：:Iridium N-heterocyclic carbene (NHC) complexes catalyse the para-hydrogen-induced hyperpolarization process, Signal Amplification by Reversible Exchange (SABRE). This process transfers the latent magnetism of para-hydrogen into a substrate, without changing its chemical identity, to dramatically improve its nuclear ma...

journal_title：Nature communications

authors： Rayner PJ,Norcott P,Appleby KM,Iali W,John RO,Hart SJ,Whitwood AC,Duckett SB

更新日期：2018-10-12 00:00:00

abstract：:In the original version of this Article, financial support and contributions in manuscript preparation were not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include the following:'M.P. and P.O. would like to thank Prof. Roderick Y.H. Lim for advice during manuscript preparati...

journal_title：Nature communications

authors： Glentis A,Oertle P,Mariani P,Chikina A,El Marjou F,Attieh Y,Zaccarini F,Lae M,Loew D,Dingli F,Sirven P,Schoumacher M,Gurchenkov BG,Plodinec M,Vignjevic DM

更新日期：2018-03-07 00:00:00

abstract：:Niobium diselenide has long served as a prototype of two-dimensional charge ordering, believed to arise from an instability of the electronic structure analogous to the one-dimensional Peierls mechanism. Despite this, various anomalous properties have recently been identified experimentally, which cannot be explained ...

journal_title：Nature communications

authors： Flicker F,van Wezel J

更新日期：2015-05-07 00:00:00

abstract：:All common genome-wide association (GWA) methods rely on population structure correction, to avoid false genotype-to-phenotype associations. However, population structure correction is a stringent penalization, which also impedes identification of real associations. Using recent statistical advances, we developed a ne...

journal_title：Nature communications

authors： Klasen JR,Barbez E,Meier L,Meinshausen N,Bühlmann P,Koornneef M,Busch W,Schneeberger K

更新日期：2016-11-10 00:00:00

abstract：:To balance immunity and tolerance, the endogenous pool of Foxp3+ regulatory T (Treg) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of Treg cells is negatively regulated by the kinase Lkb1 in dendritic cells (DCs). Conditional knockout ...

journal_title：Nature communications

authors： Chen S,Fang L,Guo W,Zhou Y,Yu G,Li W,Dong K,Liu J,Luo Y,Wang B,Li Z,Zhao C,Sun Z,Shen Y,Leng Q,Zhou D,Han Z,Huang H,Ren H,Xu G,Feng X

更新日期：2018-12-13 00:00:00

abstract：:Rare genetic disorders (RGDs) often exhibit significant clinical variability among affected individuals, a disease characteristic termed variable expressivity. Recently, the aggregate effect of common variation, quantified as polygenic scores (PGSs), has emerged as an effective tool for predictions of disease risk and...

journal_title：Nature communications

authors： Oetjens MT,Kelly MA,Sturm AC,Martin CL,Ledbetter DH

更新日期：2019-10-25 00:00:00