Modulating the hierarchical fibrous assembly of Au nanoparticles with atomic precision.

abstract：:Around 40% of preterm births are attributed to ascending intrauterine infection, and Ureaplasma parvum (UP) is commonly isolated in these cases. Here we present a mouse model of ascending UP infection that resembles human disease, using vaginal inoculation combined with mild cervical injury induced by a common spermic...

journal_title：Nature communications

authors： Pavlidis I,Spiller OB,Sammut Demarco G,MacPherson H,Howie SEM,Norman JE,Stock SJ

更新日期：2020-01-10 00:00:00

abstract：:Organic semiconductors enable the fabrication of a range of lightweight and mechanically flexible optoelectronic devices. Most organic semiconductor lasers, however, have remained rigid until now, predominantly due to the need for a support substrate. Here, we use a simple fabrication process to make membrane-based, s...

journal_title：Nature communications

authors： Karl M,Glackin JME,Schubert M,Kronenberg NM,Turnbull GA,Samuel IDW,Gather MC

更新日期：2018-05-01 00:00:00

abstract：:Selector devices are indispensable components of large-scale nonvolatile memory and neuromorphic array systems. Besides the conventional silicon transistor, two-terminal ovonic threshold switching device with much higher scalability is currently the most industrially favored selector technology. However, current ovoni...

journal_title：Nature communications

authors： Jia S,Li H,Gotoh T,Longeaud C,Zhang B,Lyu J,Lv S,Zhu M,Song Z,Liu Q,Robertson J,Liu M

更新日期：2020-09-15 00:00:00

abstract：:The hallmark of Salmonella Typhimurium infection is an acute intestinal inflammatory response, which is mediated through the action of secreted bacterial effector proteins. The pro-inflammatory Salmonella effector SopA is a HECT-like E3 ligase, which was previously proposed to activate host RING ligases TRIM56 and TRI...

journal_title：Nature communications

authors： Fiskin E,Bhogaraju S,Herhaus L,Kalayil S,Hahn M,Dikic I

更新日期：2017-01-13 00:00:00

abstract：:Non-collinear spin transport is at the heart of spin or magnetization control in spintronics devices. The use of nanoscale conductors exhibiting quantum effects in transport could provide new paths for that purpose. Here we study non-collinear spin transport in a quantum dot. We use a device made out of a single-wall ...

journal_title：Nature communications

authors： Crisan AD,Datta S,Viennot JJ,Delbecq MR,Cottet A,Kontos T

更新日期：2016-01-27 00:00:00

abstract：:Decision making in dynamic environments requires discounting old evidence that may no longer inform the current state of the world. Previous work found that humans discount old evidence in a dynamic environment, but do not discount at the optimal rate. Here we investigated whether rats can optimally discount evidence ...

journal_title：Nature communications

authors： Piet AT,El Hady A,Brody CD

更新日期：2018-10-15 00:00:00

abstract：:Myelinating oligodendrocytes enable fast propagation of action potentials along the ensheathed axons. In addition, oligodendrocytes play diverse non-canonical roles including axonal metabolic support and activity-dependent myelination. An open question remains whether myelination also contributes to information proces...

journal_title：Nature communications

authors： Moore S,Meschkat M,Ruhwedel T,Trevisiol A,Tzvetanova ID,Battefeld A,Kusch K,Kole MHP,Strenzke N,Möbius W,de Hoz L,Nave KA

更新日期：2020-10-30 00:00:00

abstract：:For many stochastic processes, the probability [Formula: see text] of not-having reached a target in unbounded space up to time [Formula: see text] follows a slow algebraic decay at long times, [Formula: see text]. This is typically the case of symmetric compact (i.e. recurrent) random walks. While the persistence exp...

journal_title：Nature communications

authors： Levernier N,Dolgushev M,Bénichou O,Voituriez R,Guérin T

更新日期：2019-07-05 00:00:00

abstract：:The original version of this Article contained an error in Figure 4. In panel a, the colour code for hot and cold clusters was inadvertently inverted. In the correct version of panel a, the hot clusters are blue and the cold clusters are yellow. This error has now been corrected in both the PDF and HTML versions of th...

journal_title：Nature communications

authors： Chakravarthy A,Furness A,Joshi K,Ghorani E,Ford K,Ward MJ,King EV,Lechner M,Marafioti T,Quezada SA,Thomas GJ,Feber A,Fenton TR

更新日期：2018-11-02 00:00:00

abstract：:Stimuli-responsive behaviors of flexible metal-organic frameworks (MOFs) make these materials promising in a wide variety of applications such as gas separation, drug delivery, and molecular sensing. Considerable efforts have been made over the last decade to understand the structural changes of flexible MOFs in respo...

journal_title：Nature communications

authors： Zhao P,Fang H,Mukhopadhyay S,Li A,Rudić S,McPherson IJ,Tang CC,Fairen-Jimenez D,Tsang SCE,Redfern SAT

更新日期：2019-03-01 00:00:00

abstract：:CRISPR-Cas9 has emerged as a powerful technology that relies on Cas9/sgRNA ribonucleoprotein complexes (RNPs) to target and edit DNA. However, many therapeutic targets cannot currently be accessed due to the lack of carriers that can deliver RNPs systemically. Here, we report a generalizable methodology that allows en...

journal_title：Nature communications

authors： Wei T,Cheng Q,Min YL,Olson EN,Siegwart DJ

更新日期：2020-06-26 00:00:00

abstract：:Sepsis is a life-threatening condition triggered by a dysregulated host response to microbial infection resulting in vascular dysfunction, organ failure and death. Here we provide a semi-quantitative atlas of the murine vascular cell-surface proteome at the organ level, and how it changes during sepsis. Using in vivo ...

journal_title：Nature communications

authors： Toledo AG,Golden G,Campos AR,Cuello H,Sorrentino J,Lewis N,Varki N,Nizet V,Smith JW,Esko JD

更新日期：2019-10-11 00:00:00

abstract：:Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in turn delivers FAs into adipocytes. During the process, binding of FAs to CD36 activates its downstream kinase LYN, which phosphorylates DH...

journal_title：Nature communications

authors： Hao JW,Wang J,Guo H,Zhao YY,Sun HH,Li YF,Lai XY,Zhao N,Wang X,Xie C,Hong L,Huang X,Wang HR,Li CB,Liang B,Chen S,Zhao TJ

更新日期：2020-09-21 00:00:00

abstract：:Yeast lacks dedicated photoreceptors; however, blue light still causes pronounced oscillations of the transcription factor Msn2 into and out of the nucleus. Here we show that this poorly understood phenomenon is initiated by a peroxisomal oxidase, which converts light into a hydrogen peroxide (H2O2) signal that is sen...

journal_title：Nature communications

authors： Bodvard K,Peeters K,Roger F,Romanov N,Igbaria A,Welkenhuysen N,Palais G,Reiter W,Toledano MB,Käll M,Molin M

更新日期：2017-03-24 00:00:00

abstract：:Timescales of magma ascent in conduit models are typically assumed to be much longer than crystallization and gas exsolution for basaltic eruptions. However, it is now recognized that basaltic magmas may rise fast enough for disequilibrium processes to play a key role on the ascent dynamics. The quantification of the ...

journal_title：Nature communications

authors： La Spina G,Burton M,De' Michieli Vitturi M,Arzilli F

更新日期：2016-12-12 00:00:00

abstract：:The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important components of the metastatic tumor microenvironment and exhibit heterogeneity. However, the specific phenotypes, funct...

journal_title：Nature communications

authors： Wang X,Hu LP,Qin WT,Yang Q,Chen DY,Li Q,Zhou KX,Huang PQ,Xu CJ,Li J,Yao LL,Wang YH,Tian GA,Yang JY,Yang MW,Liu DJ,Sun YW,Jiang SH,Zhang XL,Zhang ZG

更新日期：2021-01-08 00:00:00

abstract：:A magnetic impurity coupled to a superconductor gives rise to a Yu-Shiba-Rusinov (YSR) state inside the superconducting energy gap. With increasing exchange coupling the excitation energy of this state eventually crosses zero and the system switches to a YSR ground state with bound quasiparticles screening the impurit...

journal_title：Nature communications

authors： Grove-Rasmussen K,Steffensen G,Jellinggaard A,Madsen MH,Žitko R,Paaske J,Nygård J

更新日期：2018-06-18 00:00:00

abstract：:Application of coherent light-matter interactions has recently been extended to the ultrafast control of magnetization. An important but unrealized technique is the manipulation of magnetization vector motion to make it follow an arbitrarily designed multidimensional trajectory. Here we demonstrate a full manipulation...

journal_title：Nature communications

authors： Kanda N,Higuchi T,Shimizu H,Konishi K,Yoshioka K,Kuwata-Gonokami M

更新日期：2011-06-21 00:00:00

abstract：:Mechanical signals play many roles in cell and developmental biology. Several mechanotransduction pathways have been uncovered, but the mechanisms identified so far only address the perception of stress intensity. Mechanical stresses are tensorial in nature, and thus provide dual mechanical information: stress magnitu...

journal_title：Nature communications

authors： Hamant O,Inoue D,Bouchez D,Dumais J,Mjolsness E

更新日期：2019-05-29 00:00:00

abstract：:Chloroplast function requires the coordinated action of nuclear- and chloroplast-derived proteins, including several hundred nuclear-encoded pentatricopeptide repeat (PPR) proteins that regulate plastid mRNA metabolism. Despite their large number and importance, regulatory mechanisms controlling PPR expression are poo...

journal_title：Nature communications

authors： Bailey M,Ivanauskaite A,Grimmer J,Akintewe O,Payne AC,Osborne R,Labandera AM,Etherington RD,Rantala M,Baginsky S,Mulo P,Gibbs DJ

更新日期：2021-01-11 00:00:00

abstract：:Nitric oxide (NO) has important functions in biology and atmospheric chemistry as a toxin, signaling molecule, ozone depleting agent and the precursor of the greenhouse gas nitrous oxide (N2O). Although NO is a potent oxidant, and was available on Earth earlier than oxygen, it is unclear whether NO can be used by micr...

journal_title：Nature communications

authors： Hu Z,Wessels HJCT,van Alen T,Jetten MSM,Kartal B

更新日期：2019-03-20 00:00:00

abstract：:Valosin-containing protein (VCP, also called p97) is an essential and highly conserved adenosine triphosphate-dependent chaperone implicated in a wide range of cellular processes in eukaryotes, and mild VCP mutations can cause severe neurodegenerative disease. Here we show that mammalian VCP is trimethylated on Lys315...

journal_title：Nature communications

authors： Kernstock S,Davydova E,Jakobsson M,Moen A,Pettersen S,Mælandsmo GM,Egge-Jacobsen W,Falnes PØ

更新日期：2012-01-01 00:00:00

abstract：:A platform for highly parallel direct sequencing of native RNA strands was recently described by Oxford Nanopore Technologies, but despite initial efforts it remains crucial to further investigate the technology for quantification of complex transcriptomes. Here we undertake native RNA sequencing of polyA + RNA from t...

journal_title：Nature communications

authors： Soneson C,Yao Y,Bratus-Neuenschwander A,Patrignani A,Robinson MD,Hussain S

更新日期：2019-07-31 00:00:00

abstract：:In recent years, there has been marked increase in research aimed to introduce alkali vapours into guided-wave configurations. Owing to the significant reduction in device dimensions, the increase in density of states, the interaction with surfaces and primarily the high intensities carried along the structure, a plet...

journal_title：Nature communications

authors： Stern L,Desiatov B,Mazurski N,Levy U

更新日期：2017-02-09 00:00:00

abstract：:Currently, solar-thermal energy storage within phase-change materials relies on adding high thermal-conductivity fillers to improve the thermal-diffusion-based charging rate, which often leads to limited enhancement of charging speed and sacrificed energy storage capacity. Here we report the exploration of a magnetica...

journal_title：Nature communications

authors： Wang Z,Tong Z,Ye Q,Hu H,Nie X,Yan C,Shang W,Song C,Wu J,Wang J,Bao H,Tao P,Deng T

更新日期：2017-11-14 00:00:00

abstract：:Epigenetic regulation plays an important role in governing stem cell fate and tumorigenesis. Lost expression of a key DNA demethylation enzyme TET2 is associated with human cancers and has been linked to stem cell traits in vitro; however, whether and how TET2 regulates mammary stem cell fate and mammary tumorigenesis...

journal_title：Nature communications

authors： Kim MR,Wu MJ,Zhang Y,Yang JY,Chang CJ

更新日期：2020-09-15 00:00:00

abstract：:Avoiding repeated mistakes and learning to reinforce rewarding decisions is critical for human survival and adaptive actions. Yet, the neural underpinnings of the value systems that encode different decision-outcomes remain elusive. Here coupling single-trial electroencephalography with simultaneously acquired functio...

journal_title：Nature communications

authors： Fouragnan E,Retzler C,Mullinger K,Philiastides MG

更新日期：2015-09-08 00:00:00

abstract：:Ferroelectrics based on proton tautomerism are promising in low-field and above-room-temperature operations. Here seven organic ferroelectric crystals are examined to search for efficient switching of strong spontaneous polarization on proton tautomerism. Solution-grown crystals exhibit strong pinning of ferroelectric...

journal_title：Nature communications

authors： Horiuchi S,Kobayashi K,Kumai R,Ishibashi S

更新日期：2017-02-16 00:00:00

abstract：:Loss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to chronic inflammation and increased morbidity and mortality during antiretroviral-treated HIV disease. Sexual practice has recently been uncovered as a major source of microbiota variation, potentially confounding prior...

journal_title：Nature communications

authors： Vujkovic-Cvijin I,Sortino O,Verheij E,Sklar J,Wit FW,Kootstra NA,Sellers B,Brenchley JM,Ananworanich J,Loeff MSV,Belkaid Y,Reiss P,Sereti I

更新日期：2020-05-15 00:00:00

abstract：:Multidrug resistance is a major challenge to cancer chemotherapy. The multidrug resistance phenotype is associated with the overexpression of the adenosine triphosphate (ATP)-driven transmembrane efflux pumps in cancer cells. Here, we report a lipid membrane-coated silica-carbon (LSC) hybrid nanoparticle that targets ...

journal_title：Nature communications

authors： Wang H,Gao Z,Liu X,Agarwal P,Zhao S,Conroy DW,Ji G,Yu J,Jaroniec CP,Liu Z,Lu X,Li X,He X

更新日期：2018-02-08 00:00:00