Design of an inherently-stable water oxidation catalyst.

abstract：:To fully exploit the microbial genome resources, a high-throughput experimental platform is needed to associate genes with phenotypes at the genome level. We present here a novel method that enables investigation of the cellular consequences of repressing individual transcripts based on the CRISPR interference (CRISPR...

journal_title：Nature communications

authors： Wang T,Guan C,Guo J,Liu B,Wu Y,Xie Z,Zhang C,Xing XH

更新日期：2018-06-26 00:00:00

abstract：:UV vision is prevalent, but we know little about its utility in common general tasks, as in resolving habitat structure. Here we visualize vegetated habitats using a multispectral camera with channels mimicking bird photoreceptor sensitivities across the UV-visible spectrum. We find that the contrast between upper and...

journal_title：Nature communications

authors： Tedore C,Nilsson DE

更新日期：2019-01-22 00:00:00

abstract：:Many photosynthetic organisms globally, including crops, forests and algae, must grow in environments where the availability of light energy fluctuates dramatically. How photosynthesis maintains high efficiency despite such fluctuations in its energy source remains poorly understood. Here we show that Arabidopsis thal...

journal_title：Nature communications

authors： Armbruster U,Carrillo LR,Venema K,Pavlovic L,Schmidtmann E,Kornfeld A,Jahns P,Berry JA,Kramer DM,Jonikas MC

更新日期：2014-11-13 00:00:00

abstract：:Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear malformations in hearing loss patients including Pendred syndrome. While biallelic mutations of the SLC26A4 gene, encoding pendrin, causes non-syndromic hearing loss with EVA or Pendred syndrome, a considerable number of patients appea...

journal_title：Nature communications

authors： Li M,Nishio SY,Naruse C,Riddell M,Sapski S,Katsuno T,Hikita T,Mizapourshafiyi F,Smith FM,Cooper LT,Lee MG,Asano M,Boettger T,Krueger M,Wietelmann A,Graumann J,Day BW,Boyd AW,Offermanns S,Kitajiri SI,Usami SI,Nak

更新日期：2020-03-12 00:00:00

abstract：:A new paradigm for cellulose depolymerization by fungi focuses on an oxidative mechanism involving cellobiose dehydrogenases (CDH) and copper-dependent lytic polysaccharide monooxygenases (LPMO); however, mechanistic studies have been hampered by the lack of structural information regarding CDH. CDH contains a haem-bi...

journal_title：Nature communications

authors： Tan TC,Kracher D,Gandini R,Sygmund C,Kittl R,Haltrich D,Hällberg BM,Ludwig R,Divne C

更新日期：2015-07-07 00:00:00

abstract：:Humans typically make near-optimal sensorimotor judgements but show systematic biases when making more cognitive judgements. Here we test the hypothesis that, while humans are sensitive to the noise present during early sensory encoding, the "optimality gap" arises because they are blind to noise introduced by later c...

journal_title：Nature communications

authors： Herce Castañón S,Moran R,Ding J,Egner T,Bang D,Summerfield C

更新日期：2019-04-12 00:00:00

abstract：:Microbial production of isoprene from renewable feedstock is a promising alternative to traditional petroleum-based processes. Currently, efforts to improve isoprenoid production in Saccharomyces cerevisiae mainly focus on cytoplasmic engineering, whereas comprehensive engineering of multiple subcellular compartments ...

journal_title：Nature communications

authors： Lv X,Wang F,Zhou P,Ye L,Xie W,Xu H,Yu H

更新日期：2016-09-21 00:00:00

abstract：:Control of the collective response of plasma particles to intense laser light is intrinsic to relativistic optics, the development of compact laser-driven particle and radiation sources, as well as investigations of some laboratory astrophysics phenomena. We recently demonstrated that a relativistic plasma aperture pr...

journal_title：Nature communications

authors： Gonzalez-Izquierdo B,King M,Gray RJ,Wilson R,Dance RJ,Powell H,Maclellan DA,McCreadie J,Butler NMH,Hawkes S,Green JS,Murphy CD,Stockhausen LC,Carroll DC,Booth N,Scott GG,Borghesi M,Neely D,McKenna P

更新日期：2016-09-14 00:00:00

abstract：:Microbial population growth is typically measured when cells can be directly observed, or when death is rare. However, neither of these conditions hold for the mammalian gut microbiota, and, therefore, standard approaches cannot accurately measure the growth dynamics of this community. Here we introduce a new method (...

journal_title：Nature communications

authors： Myhrvold C,Kotula JW,Hicks WM,Conway NJ,Silver PA

更新日期：2015-11-30 00:00:00

abstract：:Solar-driven photocatalysis has attracted significant attention in water splitting, CO2 reduction and organic synthesis. The syntheses of valuable azo- and azoxyaromatic dyes via selective photoreduction of nitroaromatic compounds have been realised using supported plasmonic metal nanoparticles at elevated temperature...

journal_title：Nature communications

authors： Dai Y,Li C,Shen Y,Lim T,Xu J,Li Y,Niemantsverdriet H,Besenbacher F,Lock N,Su R

更新日期：2018-01-04 00:00:00

abstract：:Biological tissues have the remarkable ability to remodel and repair in response to disease, injury and mechanical stresses. Synthetic materials lack the complexity of biological tissues, and man-made materials that respond to external stresses through a permanent increase in stiffness are uncommon. Here we report tha...

journal_title：Nature communications

authors： Agrawal A,Chipara AC,Shamoo Y,Patra PK,Carey BJ,Ajayan PM,Chapman WG,Verduzco R

更新日期：2013-01-01 00:00:00

abstract：:Electrocatalysts for oxygen reduction are a critical component that may dramatically enhance the performance of fuel cells and metal-air batteries, which may provide the power for future electric vehicles. Here we report a novel bio-inspired composite electrocatalyst, iron phthalocyanine with an axial ligand anchored ...

journal_title：Nature communications

authors： Cao R,Thapa R,Kim H,Xu X,Gyu Kim M,Li Q,Park N,Liu M,Cho J

更新日期：2013-01-01 00:00:00

abstract：:Proteins and nucleic acids are sequence-regulated macromolecules with various properties originating from their perfectly sequenced primary structures. However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polymer chemistry. In th...

journal_title：Nature communications

authors： Satoh K,Ozawa S,Mizutani M,Nagai K,Kamigaito M

更新日期：2010-04-12 00:00:00

abstract：:A long-standing and profound problem in astronomy is the difficulty in obtaining deep near-infrared observations due to the extreme brightness and variability of the night sky at these wavelengths. A solution to this problem is crucial if we are to obtain the deepest possible observations of the early Universe, as red...

journal_title：Nature communications

authors： Bland-Hawthorn J,Ellis SC,Leon-Saval SG,Haynes R,Roth MM,Löhmannsröben HG,Horton AJ,Cuby JG,Birks TA,Lawrence JS,Gillingham P,Ryder SD,Trinh C

更新日期：2011-12-06 00:00:00

abstract：:The inheritance of the centrosome during human fertilization remains mysterious. Here we show that the sperm centrosome contains, in addition to the known typical barrel-shaped centriole (the proximal centriole, PC), a surrounding matrix (pericentriolar material, PCM), and an atypical centriole (distal centriole, DC) ...

journal_title：Nature communications

authors： Fishman EL,Jo K,Nguyen QPH,Kong D,Royfman R,Cekic AR,Khanal S,Miller AL,Simerly C,Schatten G,Loncarek J,Mennella V,Avidor-Reiss T

更新日期：2018-06-07 00:00:00

abstract：:Multilayer hexagonal boron nitride (h-BN) is highly desirable as a dielectric substrate for the fabrication of two-dimensional (2D) electronic and optoelectronic devices. However, the controllable synthesis of multilayer h-BN in large areas is still limited in terms of crystallinity, thickness and stacking order. Here...

journal_title：Nature communications

authors： Shi Z,Wang X,Li Q,Yang P,Lu G,Jiang R,Wang H,Zhang C,Cong C,Liu Z,Wu T,Wang H,Yu Q,Xie X

更新日期：2020-02-12 00:00:00

abstract：:Turn-on fluorescence imaging is routinely studied; however, turn-on chemiluminescence has been rarely explored for in vivo imaging. Herein, we report the design and validation of chemiluminescence probe ADLumin-1 as a turn-on probe for amyloid beta (Aβ) species. Two-photon imaging indicates that ADLumin-1 can efficien...

journal_title：Nature communications

authors： Yang J,Yin W,Van R,Yin K,Wang P,Zheng C,Zhu B,Ran K,Zhang C,Kumar M,Shao Y,Ran C

更新日期：2020-08-13 00:00:00

abstract：:Acanthamoeba are infected by a remarkable diversity of large dsDNA viruses, the infectious cycles of which have been characterized using genomics, transcriptomics and electron microscopy. Given their gene content and the persistence of the host nucleus throughout their infectious cycle, the Marseilleviridae were initi...

journal_title：Nature communications

authors： Fabre E,Jeudy S,Santini S,Legendre M,Trauchessec M,Couté Y,Claverie JM,Abergel C

更新日期：2017-04-21 00:00:00

abstract：:The ice- and organic-rich permafrost of the northeast Siberian Arctic lowlands (NESAL) has been projected to remain stable beyond 2100, even under pessimistic climate warming scenarios. However, the numerical models used for these projections lack processes which induce widespread landscape change termed thermokarst, ...

journal_title：Nature communications

authors： Nitzbon J,Westermann S,Langer M,Martin LCP,Strauss J,Laboor S,Boike J

更新日期：2020-05-04 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Liu X,Chen A,Caicedo-Casso A,Cui G,Du M,He Q,Lim S,Kim HJ,Hong CI,Liu Y

更新日期：2020-01-14 00:00:00

abstract：:In LaAlO(3)/SrTiO(3) heterointerfaces, charge carriers migrate from the LaAlO(3) to the interface in an electronic reconstruction. Magnetism has been observed in LaAlO(3)/SrTiO(3), but its relationship to the interface conductivity is unknown. Here we show that reconstruction is necessary, but not sufficient, for the ...

journal_title：Nature communications

authors： Kalisky B,Bert JA,Klopfer BB,Bell C,Sato HK,Hosoda M,Hikita Y,Hwang HY,Moler KA

更新日期：2012-06-26 00:00:00

abstract：:Berry phase associated with energy bands in crystals can lead to quantised observables like quantised dipole polarizations in one-dimensional topological insulators. Recent theories have generalised the concept of quantised dipoles to multipoles, resulting in the discovery of multipole topological insulators which exh...

journal_title：Nature communications

authors： Xue H,Ge Y,Sun HX,Wang Q,Jia D,Guan YJ,Yuan SQ,Chong Y,Zhang B

更新日期：2020-05-15 00:00:00

abstract：:Deep learning algorithms have been successfully used in medical image classification. In the next stage, the technology of acquiring explainable knowledge from medical images is highly desired. Here we show that deep learning algorithm enables automated acquisition of explainable features from diagnostic annotation-fr...

journal_title：Nature communications

authors： Yamamoto Y,Tsuzuki T,Akatsuka J,Ueki M,Morikawa H,Numata Y,Takahara T,Tsuyuki T,Tsutsumi K,Nakazawa R,Shimizu A,Maeda I,Tsuchiya S,Kanno H,Kondo Y,Fukumoto M,Tamiya G,Ueda N,Kimura G

更新日期：2019-12-18 00:00:00

abstract：:Surface-supported isolated atoms in single-atom catalysts (SACs) are usually stabilized by diverse defects. The fabrication of high-metal-loading and thermally stable SACs remains a formidable challenge due to the difficulty of creating high densities of underpinning stable defects. Here we report that isolated Pt ato...

journal_title：Nature communications

authors： Lang R,Xi W,Liu JC,Cui YT,Li T,Lee AF,Chen F,Chen Y,Li L,Li L,Lin J,Miao S,Liu X,Wang AQ,Wang X,Luo J,Qiao B,Li J,Zhang T

更新日期：2019-01-16 00:00:00

abstract：:Malaria is a major public health problem that is actively being addressed in a global eradication campaign. Increased population mobility through international air travel has elevated the risk of re-introducing parasites to elimination areas and dispersing drug-resistant parasites to new regions. A simple genetic mark...

journal_title：Nature communications

authors： Preston MD,Campino S,Assefa SA,Echeverry DF,Ocholla H,Amambua-Ngwa A,Stewart LB,Conway DJ,Borrmann S,Michon P,Zongo I,Ouédraogo JB,Djimde AA,Doumbo OK,Nosten F,Pain A,Bousema T,Drakeley CJ,Fairhurst RM,Sutherland CJ

更新日期：2014-06-13 00:00:00

abstract：:Owing to the significant difference in the numbers of simulated and experimentally feasible zeolite structures, several alternative strategies have been developed for zeolite synthesis. Despite their rationality and originality, most of these techniques are based on trial-and-error, which makes it difficult to predict...

journal_title：Nature communications

authors： Kasneryk V,Shamzhy M,Zhou J,Yue Q,Mazur M,Mayoral A,Luo Z,Morris RE,Čejka J,Opanasenko M

更新日期：2019-11-12 00:00:00

abstract：:Loss of appetite or anorexia associated with inflammation impairs quality of life and increases morbidity in many diseases. However, the exact neural mechanism that mediates inflammation-associated anorexia is still poorly understood. Here we identified a population of neurons, marked by the expression of protein kina...

journal_title：Nature communications

authors： Wang Y,Kim J,Schmit MB,Cho TS,Fang C,Cai H

更新日期：2019-06-24 00:00:00

abstract：:Conjugated polymeric molecules have been heralded as promising electrode materials for the next-generation energy-storage technologies owing to their chemical flexibility at the molecular level, environmental benefit, and cost advantage. However, before any practical implementation takes place, the low capacity, poor ...

journal_title：Nature communications

authors： Lei Z,Yang Q,Xu Y,Guo S,Sun W,Liu H,Lv LP,Zhang Y,Wang Y

更新日期：2018-02-08 00:00:00

abstract：:Current machine learning classifiers have successfully been applied to whole-genome sequencing data to identify genetic determinants of antimicrobial resistance (AMR), but they lack causal interpretation. Here we present a metabolic model-based machine learning classifier, named Metabolic Allele Classifier (MAC), that...

journal_title：Nature communications

authors： Kavvas ES,Yang L,Monk JM,Heckmann D,Palsson BO

更新日期：2020-05-22 00:00:00

abstract：:Epigenetic annotation studies of genetic risk variants for multiple sclerosis (MS) implicate dysfunctional lymphocytes in MS susceptibility; however, the role of central nervous system (CNS) cells remains unclear. We investigated the effect of the risk variant, rs7665090G, located near NFKB1, on astrocytes. We demonst...

journal_title：Nature communications

authors： Ponath G,Lincoln MR,Levine-Ritterman M,Park C,Dahlawi S,Mubarak M,Sumida T,Airas L,Zhang S,Isitan C,Nguyen TD,Raine CS,Hafler DA,Pitt D

更新日期：2018-12-17 00:00:00