Author Correction: FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora.

abstract：:The neurochemical changes underlying human emotions and social behaviour are largely unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala. We show that hypocretin-1 levels are maximal during positive emoti...

journal_title：Nature communications

authors： Blouin AM,Fried I,Wilson CL,Staba RJ,Behnke EJ,Lam HA,Maidment NT,Karlsson KÆ,Lapierre JL,Siegel JM

更新日期：2013-01-01 00:00:00

abstract：:Understanding the impact of rare variants is essential to understanding human health. We analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK Biobank and 1934 phenotypes (1821 overlapping with UK Biobank) in 21,866 members of the Healthy Nevada Project (HNP) coho...

journal_title：Nature communications

authors： Cirulli ET,White S,Read RW,Elhanan G,Metcalf WJ,Tanudjaja F,Fath DM,Sandoval E,Isaksson M,Schlauch KA,Grzymski JJ,Lu JT,Washington NL

更新日期：2020-01-28 00:00:00

abstract：:This corrects the article DOI: 10.1038/ncomms15587. ...

journal_title：Nature communications

authors： Yu T,Zhou YJ,Wenning L,Liu Q,Krivoruchko A,Siewers V,Nielsen J,David F

更新日期：2018-07-13 00:00:00

abstract：:Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approaches for identifying p...

journal_title：Nature communications

authors： Mohimani H,Gurevich A,Shlemov A,Mikheenko A,Korobeynikov A,Cao L,Shcherbin E,Nothias LF,Dorrestein PC,Pevzner PA

更新日期：2018-10-02 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Jiang L,Shen Y,Guo D,Yang D,Liu J,Fei X,Yang Y,Zhang B,Lin Z,Yang F,Wang X,Wang K,Wang J,Cai Z

更新日期：2020-07-16 00:00:00

abstract：:The presence and absence of RNA modifications regulates RNA metabolism by modulating the binding of writer, reader, and eraser proteins. For 5-methylcytosine (m5C) however, it is largely unknown how it recruits or repels RNA-binding proteins. Here, we decipher the consequences of m5C deposition into the abundant non-c...

journal_title：Nature communications

authors： Sajini AA,Choudhury NR,Wagner RE,Bornelöv S,Selmi T,Spanos C,Dietmann S,Rappsilber J,Michlewski G,Frye M

更新日期：2019-06-11 00:00:00

abstract：:The anterior temporal lobes (ATL) have become a key brain region of interest in cognitive neuroscience founded upon neuropsychological investigations of semantic dementia (SD). The purposes of this investigation are to generate a single unified model that captures the known cognitive-behavioural variations in SD and m...

journal_title：Nature communications

authors： Ding J,Chen K,Liu H,Huang L,Chen Y,Lv Y,Yang Q,Guo Q,Han Z,Lambon Ralph MA

更新日期：2020-05-22 00:00:00

abstract：:The human gastric mucosa is the most active layer of the stomach wall, involved in food digestion, metabolic processes and gastric carcinogenesis. Anatomically, the human stomach is divided into seven regions, but the protein basis for cellular specialization is not well understood. Here we present a global analysis o...

journal_title：Nature communications

authors： Ni X,Tan Z,Ding C,Zhang C,Song L,Yang S,Liu M,Jia R,Zhao C,Song L,Liu W,Zhou Q,Gong T,Li X,Tai Y,Zhu W,Shi T,Wang Y,Xu J,Zhen B,Qin J

更新日期：2019-01-03 00:00:00

abstract：:Transition metal-catalyzed C-H activation and radical reactions are two versatile strategies to construct diverse organic skeletons. Here we show the construction of a class of flavylium fluorophores via the merge of radical chemistry and C-H activation starting from (hetero)aryl ketones and alkynes. This protocol is ...

journal_title：Nature communications

authors： Yin J,Zhang Y,Li J,Zhu L,Lan Y,You J

更新日期：2019-12-11 00:00:00

abstract：:Quantum technology promises revolutionizing applications in information processing, communications, sensing and modelling. However, efficient on-demand cooling of the functional quantum degrees of freedom remains challenging in many solid-state implementations, such as superconducting circuits. Here we demonstrate dir...

journal_title：Nature communications

authors： Tan KY,Partanen M,Lake RE,Govenius J,Masuda S,Möttönen M

更新日期：2017-05-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hirata M,Asano N,Katayama K,Yoshida A,Tsuda Y,Sekimizu M,Mitani S,Kobayashi E,Komiyama M,Fujimoto H,Goto T,Iwamoto Y,Naka N,Iwata S,Nishida Y,Hiruma T,Hiraga H,Kawano H,Motoi T,Oda Y,Matsubara D,Fujita M,Shiba

更新日期：2020-02-19 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a photoswitchable ag...

journal_title：Nature communications

authors： Laprell L,Repak E,Franckevicius V,Hartrampf F,Terhag J,Hollmann M,Sumser M,Rebola N,DiGregorio DA,Trauner D

更新日期：2015-08-27 00:00:00

abstract：:The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., once in 10...

journal_title：Nature communications

authors： Zhang W,Zhou T,Zou L,Zhang L,Chen X

更新日期：2018-08-08 00:00:00

abstract：:Nonequilibrium atomic structures can host exotic and technologically relevant properties in otherwise conventional materials. Oxygen octahedral rotation forms a fundamental atomic distortion in perovskite oxides, but only a few patterns are predominantly present at equilibrium. This has restricted the range of possibl...

journal_title：Nature communications

authors： Kim JR,Jang J,Go KJ,Park SY,Roh CJ,Bonini J,Kim J,Lee HG,Rabe KM,Lee JS,Choi SY,Noh TW,Lee D

更新日期：2020-10-02 00:00:00

abstract：:Accumulating evidence suggests that transcriptional regulation is required for maintenance of long-term memories (LTMs). Here we characterize global transcriptional and epigenetic changes that occur during LTM storage in the Drosophila mushroom bodies (MBs), structures important for memory. Although LTM formation requ...

journal_title：Nature communications

authors： Hirano Y,Ihara K,Masuda T,Yamamoto T,Iwata I,Takahashi A,Awata H,Nakamura N,Takakura M,Suzuki Y,Horiuchi J,Okuno H,Saitoe M

更新日期：2016-11-14 00:00:00

abstract：:Ultra-long metal nanowires and their facile fabrication have been long sought after as they promise to offer substantial improvements of performance in numerous applications. However, ultra-long metal ultrafine/nanowires are beyond the capability of current manufacturing techniques, which impose limitations on their s...

journal_title：Nature communications

authors： Hwang I,Guan Z,Cao C,Tang W,Chui CO,Li X

更新日期：2020-11-23 00:00:00

abstract：:The analysis of whole-genome sequencing studies is challenging due to the large number of noncoding rare variants, our limited understanding of their functional effects, and the lack of natural units for testing. Here we propose a scan statistic framework, WGScan, to simultaneously detect the existence, and estimate t...

journal_title：Nature communications

authors： He Z,Xu B,Buxbaum J,Ionita-Laza I

更新日期：2019-07-09 00:00:00

abstract：:Centrioles are vital cellular structures that form centrosomes and cilia. The formation and function of cilia depends on a set of centriole's distal appendages. In this study, we use correlative super resolution and electron microscopy to precisely determine where distal appendage proteins localize in relation to the ...

journal_title：Nature communications

authors： Bowler M,Kong D,Sun S,Nanjundappa R,Evans L,Farmer V,Holland A,Mahjoub MR,Sui H,Loncarek J

更新日期：2019-03-01 00:00:00

abstract：:A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20006-5. ...

journal_title：Nature communications

authors： Escalera-Zamudio M,Golden M,Gutiérrez B,Thézé J,Keown JR,Carrique L,Bowden TA,Pybus OG

更新日期：2020-11-23 00:00:00

abstract：:The tumour suppressor CYLD is a deubiquitinase previously shown to inhibit NF-κB, MAP kinase and Wnt signalling. However, the tumour suppressing mechanisms of CYLD remain poorly understood. Here we show that loss of CYLD catalytic activity causes impaired DNA damage-induced p53 stabilization and activation in epitheli...

journal_title：Nature communications

authors： Fernández-Majada V,Welz PS,Ermolaeva MA,Schell M,Adam A,Dietlein F,Komander D,Büttner R,Thomas RK,Schumacher B,Pasparakis M

更新日期：2016-08-26 00:00:00

abstract：:In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC). GC B-cell-to-PC transition involves a major transcriptional switch that promotes a halt in cell proliferation and the production of s...

journal_title：Nature communications

authors： Pérez-García A,Marina-Zárate E,Álvarez-Prado ÁF,Ligos JM,Galjart N,Ramiro AR

更新日期：2017-07-05 00:00:00

abstract：:Injury and loss of oligodendrocytes can cause demyelinating diseases such as multiple sclerosis. To improve our understanding of human oligodendrocyte development, which could facilitate development of remyelination-based treatment strategies, here we describe time-course single-cell-transcriptomic analysis of develop...

journal_title：Nature communications

authors： Chamling X,Kallman A,Fang W,Berlinicke CA,Mertz JL,Devkota P,Pantoja IEM,Smith MD,Ji Z,Chang C,Kaushik A,Chen L,Whartenby KA,Calabresi PA,Mao HQ,Ji H,Wang TH,Zack DJ

更新日期：2021-01-28 00:00:00

abstract：:This corrects the article DOI: 10.1038/ncomms15317. ...

journal_title：Nature communications

authors： Lovrak M,Hendriksen WEJ,Maity C,Mytnyk S,van Steijn V,Eelkema R,van Esch JH

更新日期：2017-06-30 00:00:00

abstract：:Graphene is a single-atomic-layer material with excellent mechanical properties and has the potential to enhance the strength of composites. Its two-dimensional geometry, high intrinsic strength and modulus can effectively constrain dislocation motion, resulting in the significant strengthening of metals. Here we demo...

journal_title：Nature communications

authors： Kim Y,Lee J,Yeom MS,Shin JW,Kim H,Cui Y,Kysar JW,Hone J,Jung Y,Jeon S,Han SM

更新日期：2013-01-01 00:00:00

abstract：:While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are poorly understood. Here we define intercellular interactions between developing NK cells and stromal cells which, through contact-dependent mechanisms, promote the generat...

journal_title：Nature communications

authors： Mace EM,Gunesch JT,Dixon A,Orange JS

更新日期：2016-07-20 00:00:00

abstract：:As influenza A viruses remain a major threat to human health worldwide, the discovery of broadly neutralizing monoclonal antibodies that recognize conserved epitopes would facilitate the development of antibody-based therapeutic strategies. Here we report that a VH4-4-encoded human mAb named 3E1 could neutralize H1 an...

journal_title：Nature communications

authors： Wang W,Sun X,Li Y,Su J,Ling Z,Zhang T,Wang F,Zhang H,Chen H,Ding J,Sun B

更新日期：2016-12-02 00:00:00

abstract：:NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologues in yeast and bacteria. Rare, missense substitutions in NHE9 are genetically linked with autism but have not been functionally evaluated. Here we use evolutionary conservation analysis to build a model structure of NHE9 based on the crystal structu...

journal_title：Nature communications

authors： Kondapalli KC,Hack A,Schushan M,Landau M,Ben-Tal N,Rao R

更新日期：2013-01-01 00:00:00

abstract：:High-aspect ratio nanostructures such as nanowires and nanotubes are a powerful new tool for accessing the cell interior for delivery and sensing. Controlling and optimizing cellular access is a critical challenge for this new technology, yet even the most basic aspect of this process, whether these structures directl...

journal_title：Nature communications

authors： Xu AM,Aalipour A,Leal-Ortiz S,Mekhdjian AH,Xie X,Dunn AR,Garner CC,Melosh NA

更新日期：2014-04-07 00:00:00

abstract：:Peptide macrocycles are promising therapeutic molecules because they are protease resistant, structurally rigid, membrane permeable, and capable of modulating protein-protein interactions. Here, we report the characterization of the dual function macrocyclase-peptidase enzyme involved in the biosynthesis of the highly...

journal_title：Nature communications

authors： Czekster CM,Ludewig H,McMahon SA,Naismith JH

更新日期：2017-10-19 00:00:00

abstract：:We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability ...

journal_title：Nature communications

authors： Pirastu N,Joshi PK,de Vries PS,Cornelis MC,McKeigue PM,Keum N,Franceschini N,Colombo M,Giovannucci EL,Spiliopoulou A,Franke L,North KE,Kraft P,Morrison AC,Esko T,Wilson JF

更新日期：2018-06-29 00:00:00