Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma.


:An amendment to this paper has been published and can be accessed via a link at the top of the paper.


Nat Commun


Nature communications


Hirata M,Asano N,Katayama K,Yoshida A,Tsuda Y,Sekimizu M,Mitani S,Kobayashi E,Komiyama M,Fujimoto H,Goto T,Iwamoto Y,Naka N,Iwata S,Nishida Y,Hiruma T,Hiraga H,Kawano H,Motoi T,Oda Y,Matsubara D,Fujita M,Shiba




Has Abstract


2020-02-19 00:00:00












  • Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia.

    abstract::The transdifferentiation of pancreatic acinar cells to a ductal phenotype (acinar-to-ductal metaplasia, ADM) occurs after injury or inflammation of the pancreas and is a reversible process. However, in the presence of activating Kras mutations or persistent epidermal growth factor receptor (EGF-R) signalling, cells th...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Liou GY,Döppler H,Braun UB,Panayiotou R,Scotti Buzhardt M,Radisky DC,Crawford HC,Fields AP,Murray NR,Wang QJ,Leitges M,Storz P

    更新日期:2015-02-20 00:00:00

  • Author Correction: Fermiology and electron dynamics of trilayer nickelate La4Ni3O10.

    abstract::The original version of this Article contained errors in Fig. 2, Fig. 3a-c and Supplementary Fig. 2. In Fig. 2g and Supplementary Fig. 2, the band structure plot calculated from density function theory (DFT) had a missing band of mainly z2 character that starts at about - 0.25 eV at the Y point and disperses downwards...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误


    authors: Li H,Zhou X,Nummy T,Zhang J,Pardo V,Pickett WE,Mitchell JF,Dessau DS

    更新日期:2018-05-11 00:00:00

  • Examining charitable giving in real-world online donations.

    abstract::The current study uses big data to study prosocial behavior by analyzing donations made on the GoFundMe platform. In a dataset of more than $44 million in online donations, we find that 21% were made while opting to be anonymous to the public, with survey results indicating that 11% of these anonymous donations (2.3% ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Sisco MR,Weber EU

    更新日期:2019-09-03 00:00:00

  • Simulation of non-Abelian gauge theories with optical lattices.

    abstract::Many phenomena occurring in strongly correlated quantum systems still await conclusive explanations. The absence of isolated free quarks in nature is an example. It is attributed to quark confinement, whose origin is not yet understood. The phase diagram for nuclear matter at general temperatures and densities, studie...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Tagliacozzo L,Celi A,Orland P,Mitchell MW,Lewenstein M

    更新日期:2013-01-01 00:00:00

  • Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.

    abstract::Epithelial-to-mesenchymal transition-like (EMT-like) is a critical process allowing initiation of metastases during tumour progression. Here, to investigate its role in intestinal cancer, we combine computational network-based and experimental approaches to create a mouse model with high metastatic potential. Construc...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Chanrion M,Kuperstein I,Barrière C,El Marjou F,Cohen D,Vignjevic D,Stimmer L,Paul-Gilloteaux P,Bièche I,Tavares Sdos R,Boccia GF,Cacheux W,Meseure D,Fre S,Martignetti L,Legoix-Né P,Girard E,Fetler L,Barillot E,Louva

    更新日期:2014-10-08 00:00:00

  • A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay.

    abstract::Nonsense-mediated decay (NMD) eliminates transcripts with premature termination codons. Although NMD-induced loss-of-function has been shown to contribute to the genesis of particular cancers, its global functional consequence in tumours has not been characterized. Here we develop an algorithm to predict NMD and apply...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Hu Z,Yau C,Ahmed AA

    更新日期:2017-06-26 00:00:00

  • Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins.

    abstract::Phagocytosis is responsible for the elimination of particles of widely disparate sizes, from large fungi or effete cells to small bacteria. Though superficially similar, the molecular mechanisms involved differ: engulfment of large targets requires phosphoinositide 3-kinase (PI3K), while that of small ones does not. H...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Schlam D,Bagshaw RD,Freeman SA,Collins RF,Pawson T,Fairn GD,Grinstein S

    更新日期:2015-10-14 00:00:00

  • Publisher Correction: Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division.

    abstract::The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误


    authors: Pazos M,Peters K,Casanova M,Palacios P,VanNieuwenhze M,Breukink E,Vicente M,Vollmer W

    更新日期:2019-01-30 00:00:00

  • Atomically engineering activation sites onto metallic 1T-MoS2 catalysts for enhanced electrochemical hydrogen evolution.

    abstract::Engineering catalytic sites at the atomic level provides an opportunity to understand the catalyst's active sites, which is vital to the development of improved catalysts. Here we show a reliable and tunable polyoxometalate template-based synthetic strategy to atomically engineer metal doping sites onto metallic 1T-Mo...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Huang Y,Sun Y,Zheng X,Aoki T,Pattengale B,Huang J,He X,Bian W,Younan S,Williams N,Hu J,Ge J,Pu N,Yan X,Pan X,Zhang L,Wei Y,Gu J

    更新日期:2019-02-28 00:00:00

  • Structural and functional analysis of the human POT1-TPP1 telomeric complex.

    abstract::POT1 and TPP1 are part of the shelterin complex and are essential for telomere length regulation and maintenance. Naturally occurring mutations of the telomeric POT1-TPP1 complex are implicated in familial glioma, melanoma and chronic lymphocytic leukaemia. Here we report the atomic structure of the interacting portio...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Rice C,Shastrula PK,Kossenkov AV,Hills R,Baird DM,Showe LC,Doukov T,Janicki S,Skordalakes E

    更新日期:2017-04-10 00:00:00

  • The induction and function of the anti-inflammatory fate of TH17 cells.

    abstract::TH17 cells exemplify environmental immune adaptation: they can acquire both a pathogenic and an anti-inflammatory fate. However, it is not known whether the anti-inflammatory fate is merely a vestigial trait, or whether it serves to preserve the integrity of the host tissues. Here we show that the capacity of TH17 cel...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Xu H,Agalioti T,Zhao J,Steglich B,Wahib R,Vesely MCA,Bielecki P,Bailis W,Jackson R,Perez D,Izbicki J,Licona-Limón P,Kaartinen V,Geginat J,Esplugues E,Tolosa E,Huber S,Flavell RA,Gagliani N

    更新日期:2020-07-03 00:00:00

  • Epistasis between adults and larvae underlies caste fate and fitness in a clonal ant.

    abstract::In social species, the phenotype and fitness of an individual depend in part on the genotype of its social partners. However, how these indirect genetic effects affect genotype fitness in competitive situations is poorly understood in animal societies. We therefore studied phenotypic plasticity and fitness of two clon...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Teseo S,Châline N,Jaisson P,Kronauer DJ

    更新日期:2014-01-01 00:00:00

  • Faster phonological processing and right occipito-temporal coupling in deaf adults signal poor cochlear implant outcome.

    abstract::The outcome of adult cochlear implantation is predicted positively by the involvement of visual cortex in speech processing, and negatively by the cross-modal recruitment of the right temporal cortex during and after deafness. How these two neurofunctional predictors concur to modulate cochlear implant (CI) performanc...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Lazard DS,Giraud AL

    更新日期:2017-03-28 00:00:00

  • Metal-centred azaphosphatriptycene gear with a photo- and thermally driven mechanical switching function based on coordination isomerism.

    abstract::Metal ions can serve as a centre of molecular motions due to their coordination geometry, reversible bonding nature and external stimuli responsiveness. Such essential features of metal ions have been utilized for metal-mediated molecular machines with the ability to motion switch via metallation/demetallation or coor...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ube H,Yasuda Y,Sato H,Shionoya M

    更新日期:2017-02-08 00:00:00

  • Nestin regulates cellular redox homeostasis in lung cancer through the Keap1-Nrf2 feedback loop.

    abstract::Abnormal cancer antioxidant capacity is considered as a potential mechanism of tumor malignancy. Modulation of oxidative stress status is emerging as an anti-cancer treatment. Our previous studies have found that Nestin-knockdown cells were more sensitive to oxidative stress in non-small cell lung cancer (NSCLC). Howe...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Wang J,Lu Q,Cai J,Wang Y,Lai X,Qiu Y,Huang Y,Ke Q,Zhang Y,Guan Y,Wu H,Wang Y,Liu X,Shi Y,Zhang K,Wang M,Peng Xiang A

    更新日期:2019-11-06 00:00:00

  • Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.

    abstract::Tissue injury and the healing response lead to the release of endogenous danger signals including Toll-like receptor (TLR) and interleukin-1 receptor, type 1 (IL-1R1) ligands, which modulate the immune microenvironment. Because TLRs and IL-1R1 have been shown to influence the repair process of various tissues, we expl...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Martino MM,Maruyama K,Kuhn GA,Satoh T,Takeuchi O,Müller R,Akira S

    更新日期:2016-03-22 00:00:00

  • Ecological constraints increase the climatic debt in forests.

    abstract::Biodiversity changes are lagging behind current climate warming. The underlying determinants of this climatic debt are unknown and yet critical to understand the impacts of climate change on the present biota and improve forecasts of biodiversity changes. Here we assess determinants of climatic debt accumulated in Fre...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Bertrand R,Riofrío-Dillon G,Lenoir J,Drapier J,de Ruffray P,Gégout JC,Loreau M

    更新日期:2016-08-26 00:00:00

  • Atomically defined angstrom-scale all-carbon junctions.

    abstract::Full-carbon electronics at the scale of several angstroms is an expeimental challenge, which could be overcome by exploiting the versatility of carbon allotropes. Here, we investigate charge transport through graphene/single-fullerene/graphene hybrid junctions using a single-molecule manipulation technique. Such sub-n...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Tan Z,Zhang D,Tian HR,Wu Q,Hou S,Pi J,Sadeghi H,Tang Z,Yang Y,Liu J,Tan YZ,Chen ZB,Shi J,Xiao Z,Lambert C,Xie SY,Hong W

    更新日期:2019-04-15 00:00:00

  • Time elapsed between Zika and dengue virus infections affects antibody and T cell responses.

    abstract::Zika virus (ZIKV) and dengue virus (DENV) are co-endemic in many parts of the world, but the impact of ZIKV infection on subsequent DENV infection is not well understood. Here we show in rhesus macaques that the time elapsed after ZIKV infection affects the immune response to DENV infection. We show that previous ZIKV...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Pérez-Guzmán EX,Pantoja P,Serrano-Collazo C,Hassert MA,Ortiz-Rosa A,Rodríguez IV,Giavedoni L,Hodara V,Parodi L,Cruz L,Arana T,White LJ,Martínez MI,Weiskopf D,Brien JD,de Silva A,Pinto AK,Sariol CA

    更新日期:2019-09-20 00:00:00

  • Exceptionally well-preserved Cretaceous microfossils reveal new biomineralization styles.

    abstract::Calcareous microplankton shells form the dominant components of ancient and modern pelagic sea-floor carbonates and are widely used in palaeoenvironmental reconstructions. The efficacy of these applications, however, is dependent upon minimal geochemical alteration during diagenesis, but these modifying processes are ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Wendler JE,Bown P

    更新日期:2013-01-01 00:00:00

  • miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit.

    abstract::Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue. Here we show that microRNA 155 is enriched in brown adipose tissue and is highly expressed in proliferating brown preadipocytes but declines after induction of ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Chen Y,Siegel F,Kipschull S,Haas B,Fröhlich H,Meister G,Pfeifer A

    更新日期:2013-01-01 00:00:00

  • LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate.

    abstract::Master transcription factors reprogram cell fate in multicellular eukaryotes. Pioneer transcription factors have prominent roles in this process because of their ability to contact their cognate binding motifs in closed chromatin. Reprogramming is pervasive in plants, whose development is plastic and tuned by the envi...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Jin R,Klasfeld S,Zhu Y,Fernandez Garcia M,Xiao J,Han SK,Konkol A,Wagner D

    更新日期:2021-01-27 00:00:00

  • Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages.

    abstract::In eukaryotes, telomeres cap chromosome ends to maintain genomic stability. Failure to maintain telomeres leads to their progressive erosion and eventually triggers replicative senescence, a pathway that protects against unrestricted cell proliferation. However, the mechanisms underlying the variability and dynamics o...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Xu Z,Fallet E,Paoletti C,Fehrmann S,Charvin G,Teixeira MT

    更新日期:2015-07-09 00:00:00

  • Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling.

    abstract::Akt2 and its downstream effectors mediate insulin-stimulated GLUT4-storage vesicle (GSV) translocation and fusion with the plasma membrane (PM). Using mass spectrometry, we identify actin-capping protein Tropomodulin 3 (Tmod3) as an Akt2-interacting partner in 3T3-L1 adipocytes. We demonstrate that Tmod3 is phosphoryl...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Lim CY,Bi X,Wu D,Kim JB,Gunning PW,Hong W,Han W

    更新日期:2015-01-09 00:00:00

  • Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.

    abstract::Collisions between the DNA replication machinery and co-transcriptional R-loops can impede DNA synthesis and are a major source of genomic instability in cancer cells. How cancer cells deal with R-loops to proliferate is poorly understood. Here we show that the ATP-dependent chromatin remodelling INO80 complex promote...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Prendergast L,McClurg UL,Hristova R,Berlinguer-Palmini R,Greener S,Veitch K,Hernandez I,Pasero P,Rico D,Higgins JMG,Gospodinov A,Papamichos-Chronakis M

    更新日期:2020-09-10 00:00:00

  • Highly explosive basaltic eruptions driven by CO2 exsolution.

    abstract::The most explosive basaltic scoria cone eruption yet documented (>20 km high plumes) occurred at Sunset Crater (Arizona) ca. 1085 AD by undetermined eruptive mechanisms. We present melt inclusion analysis, including bubble contents by Raman spectroscopy, yielding high total CO2 (approaching 6000 ppm) and S (~2000 ppm)...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Allison CM,Roggensack K,Clarke AB

    更新日期:2021-01-11 00:00:00

  • Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice.

    abstract::In retinitis pigmentosa, loss of cone photoreceptors leads to blindness, and preservation of cone function is a major therapeutic goal. However, cone loss is thought to occur as a secondary event resulting from degeneration of rod photoreceptors. Here we report a genome editing approach in which adeno-associated virus...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Yu W,Mookherjee S,Chaitankar V,Hiriyanna S,Kim JW,Brooks M,Ataeijannati Y,Sun X,Dong L,Li T,Swaroop A,Wu Z

    更新日期:2017-03-14 00:00:00

  • DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility.

    abstract::During neuronal differentiation, the transcriptional profile and the epigenetic context of neural committed cells is subject to significant rearrangements, but a systematic quantification of global histone modification changes is still missing. Here, we show that H3K79me2 increases and H3K27ac decreases globally durin...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ferrari F,Arrigoni L,Franz H,Izzo A,Butenko L,Trompouki E,Vogel T,Manke T

    更新日期:2020-10-15 00:00:00

  • ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types.

    abstract::Early dissemination, metastasis and therapy resistance are central hallmarks of aggressive cancer types and the leading cause of cancer-associated deaths. The EMT-inducing transcriptional repressor ZEB1 is a crucial stimulator of these processes, particularly by coupling the activation of cellular motility with stemne...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Lehmann W,Mossmann D,Kleemann J,Mock K,Meisinger C,Brummer T,Herr R,Brabletz S,Stemmler MP,Brabletz T

    更新日期:2016-02-15 00:00:00

  • Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials.

    abstract::Antibiotic resistance poses rapidly increasing global problems in combatting multidrug-resistant (MDR) infectious diseases like MDR tuberculosis, prompting for novel approaches including host-directed therapies (HDT). Intracellular pathogens like Salmonellae and Mycobacterium tuberculosis (Mtb) exploit host pathways t...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Korbee CJ,Heemskerk MT,Kocev D,van Strijen E,Rabiee O,Franken KLMC,Wilson L,Savage NDL,Džeroski S,Haks MC,Ottenhoff THM

    更新日期:2018-01-24 00:00:00