Abstract:
:Graphene is a single-atomic-layer material with excellent mechanical properties and has the potential to enhance the strength of composites. Its two-dimensional geometry, high intrinsic strength and modulus can effectively constrain dislocation motion, resulting in the significant strengthening of metals. Here we demonstrate a new material design in the form of a nanolayered composite consisting of alternating layers of metal (copper or nickel) and monolayer graphene that has ultra-high strengths of 1.5 and 4.0 GPa for copper-graphene with 70-nm repeat layer spacing and nickel-graphene with 100-nm repeat layer spacing, respectively. The ultra-high strengths of these metal-graphene nanolayered structures indicate the effectiveness of graphene in blocking dislocation propagation across the metal-graphene interface. Ex situ and in situ transmission electron microscopy compression tests and molecular dynamics simulations confirm a build-up of dislocations at the graphene interface.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Kim Y,Lee J,Yeom MS,Shin JW,Kim H,Cui Y,Kysar JW,Hone J,Jung Y,Jeon S,Han SMdoi
10.1038/ncomms3114subject
Has Abstractpub_date
2013-01-01 00:00:00pages
2114issn
2041-1723pii
ncomms3114journal_volume
4pub_type
杂志文章abstract::Memory consolidation requires a timely controlled interplay between the hippocampus, a brain region important for memory formation, and the cortex, a region recruited for memory storage. Here we show that memory consolidation is associated with specific epigenetic modifications on histone proteins that have a distinct...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1997
更新日期:2012-01-01 00:00:00
abstract::The Montreal Protocol has succeeded in limiting major ozone-depleting substance emissions, and consequently stratospheric ozone concentrations are expected to recover this century. However, there is a large uncertainty in the rate of regional ozone recovery in the Northern Hemisphere. Here we identify a Eurasia-North ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02565-2
更新日期:2018-01-15 00:00:00
abstract::The myogenic regulatory factor MRF4 is highly expressed in adult skeletal muscle but its function is unknown. Here we show that Mrf4 knockdown in adult muscle induces hypertrophy and prevents denervation-induced atrophy. This effect is accompanied by increased protein synthesis and widespread activation of muscle-spec...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12397
更新日期:2016-08-03 00:00:00
abstract::The bundle of stereocilia on inner ear hair cells responds to subnanometer deflections produced by sound or head movement. Stereocilia are interconnected by a variety of links and also carry an electron-dense surface coat. The coat may contribute to stereocilia adhesion or protect from stereocilia fusion, but its mole...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11712-w
更新日期:2019-08-23 00:00:00
abstract::When our experience violates our predictions, it is adaptive to upregulate encoding of novel information, while down-weighting retrieval of erroneous memory predictions to promote an updated representation of the world. We asked whether mnemonic prediction errors promote hippocampal encoding versus retrieval states, a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17287-1
更新日期:2020-07-10 00:00:00
abstract::The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer detailed reconstructions of tumor phylogenies in ten prostate cancer patients with fatal disease, and investigate them in conjunction with histopathology and tum...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18843-5
更新日期:2020-10-08 00:00:00
abstract::In the original version of this Article, extraneous text not belonging to the Article was accidentally appended to the results section. This error has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-04279-5
更新日期:2018-05-08 00:00:00
abstract::Early dissemination, metastasis and therapy resistance are central hallmarks of aggressive cancer types and the leading cause of cancer-associated deaths. The EMT-inducing transcriptional repressor ZEB1 is a crucial stimulator of these processes, particularly by coupling the activation of cellular motility with stemne...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10498
更新日期:2016-02-15 00:00:00
abstract::The insulator-metal transition (IMT) of vanadium dioxide (VO2) has remained a long-standing challenge in correlated electron physics since its discovery five decades ago. Most interpretations of experimental observations have implicitly assumed a homogeneous material response. Here we reveal inhomogeneous behaviour of...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7849
更新日期:2015-04-21 00:00:00
abstract::Increasing evidence suggests that neural population responses have their own internal drive, or dynamics, that describe how the neural population evolves through time. An important prediction of neural dynamical models is that previously observed neural activity is informative of noisy yet-to-be-observed activity on s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8759
更新日期:2015-07-29 00:00:00
abstract::The photon-like behavior of electrons in graphene causes unusual confinement properties that depend strongly on the geometry and strength of the surrounding potential. We report bottom-up synthesis of atomically-precise one-dimensional (1D) arrays of point charges on graphene that allow exploration of a new type of su...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08371-2
更新日期:2019-01-29 00:00:00
abstract::Seed germination and young seedling establishment should be tightly regulated to maximize plant survival and thereby enable successful propagation. Plants have evolved developmental signalling networks to integrate environmental cues for proper control of these critical processes, in which brassinosteroids are known t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5138
更新日期:2014-06-18 00:00:00
abstract::Explosive energy release is a common phenomenon occurring in magnetized plasma systems ranging from laboratories, Earth's magnetosphere, the solar corona and astrophysical environments. Its physical explanation is usually attributed to magnetic reconnection in a thin current sheet. Here we report the important role of...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1753
更新日期:2012-03-20 00:00:00
abstract::Cladodontomorph sharks are Palaeozoic stem chondrichthyans thought to go extinct at the end-Permian mass extinction. This extinction preceded the diversification of euselachians, including modern sharks. Here we describe an outer-platform cladodontomorph shark tooth assemblage from the Early Cretaceous of southern Fra...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3669
更新日期:2013-01-01 00:00:00
abstract::The outcome of adult cochlear implantation is predicted positively by the involvement of visual cortex in speech processing, and negatively by the cross-modal recruitment of the right temporal cortex during and after deafness. How these two neurofunctional predictors concur to modulate cochlear implant (CI) performanc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14872
更新日期:2017-03-28 00:00:00
abstract::Tpt1 is an essential agent of fungal tRNA splicing that removes the 2'-PO4 at the splice junction generated by fungal tRNA ligase. Tpt1 catalyzes a unique two-step reaction whereby the 2'-PO4 attacks NAD+ to form an RNA-2'-phospho-ADP-ribosyl intermediate that undergoes transesterification to yield 2'-OH RNA and ADP-r...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08211-9
更新日期:2019-01-15 00:00:00
abstract::Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approaches for identifying p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06082-8
更新日期:2018-10-02 00:00:00
abstract::Most chemical vapor deposition methods for transition metal dichalcogenides use an extremely small amount of precursor to render large single-crystal flakes, which usually causes low coverage of the materials on the substrate. In this study, a self-capping vapor-liquid-solid reaction is proposed to fabricate large-gra...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17517-6
更新日期:2020-07-23 00:00:00
abstract::Planar neural networks and interfaces serve as versatile in vitro models of central nervous system physiology, but adaptations of related methods to three dimensions (3D) have met with limited success. Here, we demonstrate for the first time volumetric functional imaging in a bioengineered neural tissue growing in a t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4997
更新日期:2014-06-05 00:00:00
abstract::The NASA MErcury Surface, Space ENvironment, GEochemistry and Ranging (MESSENGER) spacecraft entered orbital phase around Mercury on 18 March 2011. A surprising consistent feature in the data returned is large-scale vortices that form exclusively on the dusk side of the magnetosphere. Here we present global kinetic hy...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2676
更新日期:2013-01-01 00:00:00
abstract::Thrombocytosis is present in more than 30% of patients with solid malignancies and correlates with worsened patient survival. Tumor cell interaction with various cellular components of the tumor microenvironment including platelets is crucial for tumor growth and metastasis. Although it is known that platelets can inf...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00411-z
更新日期:2017-08-21 00:00:00
abstract::Classic, model-based theory of land-atmosphere interactions across the Sahel promote positive vegetation-rainfall feedbacks dominated by surface albedo mechanism. However, neither the proposed positive vegetation-rainfall feedback nor its underlying albedo mechanism has been convincingly demonstrated using observation...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02021-1
更新日期:2017-11-30 00:00:00
abstract::Most motile bacteria navigate within gradients of external chemical stimuli by regulating the length of randomly oriented swimming episodes. Magnetotactic bacteria are characterized by chains of intracellular ferromagnetic nanoparticles and their ability to sense the geomagnetic field, which is believed to facilitate ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6398
更新日期:2014-11-14 00:00:00
abstract::Autophagosomes are double-membrane vesicles that sequester cytoplasmic material for lysosomal degradation. Their biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. This process depends on the regulated activation of the Atg1-kinase complex. However, the underlying molecular mechan...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10338
更新日期:2016-01-12 00:00:00
abstract::Do completely unpredictable events exist? Classical physics excludes fundamental randomness. Although quantum theory makes probabilistic predictions, this does not imply that nature is random, as randomness should be certified without relying on the complete structure of the theory being used. Bell tests approach the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3654
更新日期:2013-01-01 00:00:00
abstract::The actin cytoskeleton is an active semi-flexible polymer network whose non-equilibrium properties coordinate both stable and contractile behaviors to maintain or change cell shape. While myosin motors drive the actin cytoskeleton out-of-equilibrium, the role of myosin-driven active stresses in the accumulation and di...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07413-5
更新日期:2018-11-23 00:00:00
abstract::Batesian mimicry, in which harmless species (mimics) deter predators by deceitfully imitating the warning signals of noxious species (models), generates striking cases of phenotypic convergence that are classic examples of evolution by natural selection. However, mimicry of venomous coral snakes has remained controver...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11484
更新日期:2016-05-05 00:00:00
abstract::CRISPR-Cas9 is a promising technology for genome editing. Here we use Cas9 nuclease-induced double-strand break DNA (DSB) at the UROS locus to model and correct congenital erythropoietic porphyria. We demonstrate that homology-directed repair is rare compared with NHEJ pathway leading to on-target indels and causing u...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09006-2
更新日期:2019-03-08 00:00:00
abstract::Since the 1970s, it has been known that black-hole (and other) horizons are truly thermodynamic. More generally, surfaces which are not horizons have also been conjectured to behave thermodynamically. Initially, for surfaces microscopically expanded from a horizon to so-called stretched horizons, and more recently, fo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05433-9
更新日期:2018-07-30 00:00:00
abstract::Hearing relies on mechanical stimulation of stereocilia bundles on the sensory cells of the inner ear. When sound hits the ear, each stereocilium pivots about a neck-like taper near their base. More than three decades of research have established that sideways deflection of stereocilia is essential for converting mech...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2100
更新日期:2012-01-01 00:00:00