Faster phonological processing and right occipito-temporal coupling in deaf adults signal poor cochlear implant outcome.

abstract：:Major depressive disorder is associated with abnormalities in the brain and the immune system. Chronic stress in animals showed that epigenetic and inflammatory mechanisms play important roles in mediating resilience and susceptibility to depression. Here, through a high-throughput screening, we identify two phytochem...

journal_title：Nature communications

authors： Wang J,Hodes GE,Zhang H,Zhang S,Zhao W,Golden SA,Bi W,Menard C,Kana V,Leboeuf M,Xie M,Bregman D,Pfau ML,Flanigan ME,Esteban-Fernández A,Yemul S,Sharma A,Ho L,Dixon R,Merad M,Han MH,Russo SJ,Pasinetti GM

更新日期：2018-02-02 00:00:00

abstract：:Breast cancer (BC) patients diagnosed between two screenings (interval cancers) are more likely than screen-detected patients to carry rare deleterious mutations in cancer genes potentially leading to increased risk for other non-breast cancer (non-BC) tumors. In this study, we include 14,846 women diagnosed with BC o...

journal_title：Nature communications

authors： Grassmann F,He W,Eriksson M,Gabrielson M,Hall P,Czene K

更新日期：2019-10-22 00:00:00

abstract：:Metastasis is the primary cause for mortality in breast cancer. MicroRNAs, gene expression master regulators, constitute an attractive candidate to control metastasis. Here we show that breast cancer metastasis can be prevented by miR-96 or miR-182 treatment, and decipher the mechanism of action. We found that miR-96/...

journal_title：Nature communications

authors： Gilam A,Conde J,Weissglas-Volkov D,Oliva N,Friedman E,Artzi N,Shomron N

更新日期：2016-09-19 00:00:00

abstract：:Erythropoietin (Epo) supports both primitive erythropoiesis in the yolk sac and definitive erythropoiesis in the fetal liver and bone marrow. Although definitive erythropoiesis requires kidney- and liver-secreted Epo, it is unclear which cells produce Epo for primitive erythropoiesis. Here we find neural Epo-producing...

journal_title：Nature communications

authors： Suzuki N,Hirano I,Pan X,Minegishi N,Yamamoto M

更新日期：2013-01-01 00:00:00

abstract：:Hydrogen, the simplest element in the universe, has a surprisingly complex phase diagram. Because of applications to planetary science, inertial confinement fusion and fundamental physics, its high-pressure properties have been the subject of intense study over the past two decades. While sophisticated static experime...

journal_title：Nature communications

authors： Davis P,Döppner T,Rygg JR,Fortmann C,Divol L,Pak A,Fletcher L,Becker A,Holst B,Sperling P,Redmer R,Desjarlais MP,Celliers P,Collins GW,Landen OL,Falcone RW,Glenzer SH

更新日期：2016-04-15 00:00:00

abstract：:Recent studies suggest that gut microbiomes of urban-industrialized societies are different from those of traditional peoples. Here we examine the relationship between lifeways and gut microbiota through taxonomic and functional potential characterization of faecal samples from hunter-gatherer and traditional agricult...

journal_title：Nature communications

authors： Obregon-Tito AJ,Tito RY,Metcalf J,Sankaranarayanan K,Clemente JC,Ursell LK,Zech Xu Z,Van Treuren W,Knight R,Gaffney PM,Spicer P,Lawson P,Marin-Reyes L,Trujillo-Villarroel O,Foster M,Guija-Poma E,Troncoso-Corzo L,Warinne

更新日期：2015-03-25 00:00:00

abstract：:Somatic mutations in the RNase IIIb domain of DICER1 arise in cancer and disrupt the cleavage of 5' pre-miRNA arms. Here, we characterize an unstudied, recurrent, mutation (S1344L) in the DICER1 RNase IIIa domain in tumors from The Cancer Genome Atlas (TCGA) project and MSK-IMPACT profiling. RNase IIIa/b hotspots are ...

journal_title：Nature communications

authors： Vedanayagam J,Chatila WK,Aksoy BA,Majumdar S,Skanderup AJ,Demir E,Schultz N,Sander C,Lai EC

更新日期：2019-08-15 00:00:00

abstract：:In the development of addiction, drug seeking becomes habitual and controlled by drug-associated cues, and the neural locus of control over behaviour shifts from the ventral to the dorsolateral striatum. The neural mechanisms underlying this functional transition from recreational drug use to drug-seeking habits are u...

journal_title：Nature communications

authors： Murray JE,Belin-Rauscent A,Simon M,Giuliano C,Benoit-Marand M,Everitt BJ,Belin D

更新日期：2015-12-14 00:00:00

abstract：:Memory consolidation requires a timely controlled interplay between the hippocampus, a brain region important for memory formation, and the cortex, a region recruited for memory storage. Here we show that memory consolidation is associated with specific epigenetic modifications on histone proteins that have a distinct...

journal_title：Nature communications

authors： Gräff J,Woldemichael BT,Berchtold D,Dewarrat G,Mansuy IM

更新日期：2012-01-01 00:00:00

abstract：:Intricate biomineralization processes in molluscs engineer hierarchical structures with meso-, nano- and atomic architectures that give the final composite material exceptional mechanical strength and optical iridescence on the macroscale. This multiscale biological assembly inspires new synthetic routes to complex ma...

journal_title：Nature communications

authors： Hovden R,Wolf SE,Holtz ME,Marin F,Muller DA,Estroff LA

更新日期：2015-12-03 00:00:00

abstract：:Erythropoietin regulates erythropoiesis in a hypoxia-inducible manner. Here we generate inherited super-anaemic mice (ISAM) as a mouse model of adult-onset anaemia caused by erythropoietin deficiency. ISAM express erythropoietin in the liver but lack erythropoietin production in the kidney. Around weaning age, when th...

journal_title：Nature communications

authors： Yamazaki S,Souma T,Hirano I,Pan X,Minegishi N,Suzuki N,Yamamoto M

更新日期：2013-01-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Masid M,Ataman M,Hatzimanikatis V

更新日期：2020-07-23 00:00:00

abstract：:One of the fundamental challenges in nanophotonics is to gain full control over nanoscale optical elements. The precise spatiotemporal arrangement determines their interactions and collective behavior. To this end, DNA nanotechnology is employed as an unprecedented tool to create nanophotonic devices with excellent sp...

journal_title：Nature communications

authors： Xin L,Zhou C,Duan X,Liu N

更新日期：2019-11-27 00:00:00

abstract：:Bcl9 and Pygo are Wnt enhanceosome components that effect β-catenin-dependent transcription. Whether they mediate β-catenin-dependent neoplasia is unclear. Here we assess their roles in intestinal tumourigenesis initiated by Apc loss-of-function (ApcMin), or by Apc1322T encoding a partially-functional Apc truncation c...

journal_title：Nature communications

authors： Mieszczanek J,van Tienen LM,Ibrahim AEK,Winton DJ,Bienz M

更新日期：2019-02-13 00:00:00

abstract：:Cell identity is specified in the early mammalian embryo by the generation of precursors for two cell lineages: the pluripotent inner cell mass and differentiating trophectoderm. Here we identify Angiomotin as a key regulator of this process. We show that the loss of Angiomotin, together with Angiomotin-like 2, leads ...

journal_title：Nature communications

authors： Leung CY,Zernicka-Goetz M

更新日期：2013-01-01 00:00:00

abstract：:The rapidly increasing use of sensors throughout different research disciplines and the demand for more efficient devices with less power consumption depends critically on the emergence of new sensor materials and novel sensor concepts. Atomically thin transition metal dichalcogenides have a huge potential for sensor ...

journal_title：Nature communications

authors： Feierabend M,Berghäuser G,Knorr A,Malic E

更新日期：2017-03-15 00:00:00

abstract：:Substance abuse disorders are linked to alteration of circadian rhythms, although the molecular and neuronal pathways implicated have not been fully elucidated. Addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. Here, we show that acute administration of cocaine triggers reprogr...

journal_title：Nature communications

authors： Brami-Cherrier K,Lewis RG,Cervantes M,Liu Y,Tognini P,Baldi P,Sassone-Corsi P,Borrelli E

更新日期：2020-09-07 00:00:00

abstract：:DNA methylation plays important roles in prokaryotes, and their genomic landscapes-prokaryotic epigenomes-have recently begun to be disclosed. However, our knowledge of prokaryotic methylation systems is focused on those of culturable microbes, which are rare in nature. Here, we used single-molecule real-time and circ...

journal_title：Nature communications

authors： Hiraoka S,Okazaki Y,Anda M,Toyoda A,Nakano SI,Iwasaki W

更新日期：2019-01-11 00:00:00

abstract：:The development of transistors with high gain is essential for applications ranging from switching elements and drivers to transducers for chemical and biological sensing. Organic transistors have become well-established based on their distinct advantages, including ease of fabrication, synthetic freedom for chemical ...

journal_title：Nature communications

authors： Khodagholy D,Rivnay J,Sessolo M,Gurfinkel M,Leleux P,Jimison LH,Stavrinidou E,Herve T,Sanaur S,Owens RM,Malliaras GG

更新日期：2013-01-01 00:00:00

abstract：:Finding food sources is essential for survival. Insects detect nutrients with external taste receptor neurons. Drosophila possesses multiple taste organs that are distributed throughout its body. However, the role of different taste organs in feeding remains poorly understood. By blocking subsets of sweet taste recept...

journal_title：Nature communications

authors： Thoma V,Knapek S,Arai S,Hartl M,Kohsaka H,Sirigrivatanawong P,Abe A,Hashimoto K,Tanimoto H

更新日期：2016-02-19 00:00:00

abstract：:Planar spindle orientation in polarized epithelial cells depends on the precise localization of the dynein-dynactin motor protein complex at the lateral cortex. The contribution of cell adhesion molecules to the cortical localization of the dynein-dynactin complex is poorly understood. Here we find that junctional adh...

journal_title：Nature communications

authors： Tuncay H,Brinkmann BF,Steinbacher T,Schürmann A,Gerke V,Iden S,Ebnet K

更新日期：2015-08-26 00:00:00

abstract：:Fluorescence imaging in the second near-infrared window (NIR-II) allows visualization of deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw from a broad spectrum of materials spanning semiconducting nanomaterials to organic molecular dyes, yet unfortunately all water-soluble org...

journal_title：Nature communications

authors： Antaris AL,Chen H,Diao S,Ma Z,Zhang Z,Zhu S,Wang J,Lozano AX,Fan Q,Chew L,Zhu M,Cheng K,Hong X,Dai H,Cheng Z

更新日期：2017-05-19 00:00:00

abstract：:The development of theories and methods devoted to the accurate calculation of the electronic quasi-particle states and levels of molecules, clusters and solids is of prime importance to interpret the experimental data. These quantum systems are often modelled by using the Born-Oppenheimer approximation where the coup...

journal_title：Nature communications

authors： Gali A,Demján T,Vörös M,Thiering G,Cannuccia E,Marini A

更新日期：2016-04-22 00:00:00

abstract：:Neuroendocrine prostate cancer (NEPC) is an aggressive malignancy with no effective targeted therapies. The oncogenic MUC1-C protein is overexpressed in castration-resistant prostate cancer (CRPC) and NEPC, but its specific role is unknown. Here, we demonstrate that upregulation of MUC1-C in androgen-dependent PC cell...

journal_title：Nature communications

authors： Yasumizu Y,Rajabi H,Jin C,Hata T,Pitroda S,Long MD,Hagiwara M,Li W,Hu Q,Liu S,Yamashita N,Fushimi A,Kui L,Samur M,Yamamoto M,Zhang Y,Zhang N,Hong D,Maeda T,Kosaka T,Wong KK,Oya M,Kufe D

更新日期：2020-01-17 00:00:00

abstract：:The high pathogenicity of the Ebola virus reflects multiple concurrent processes on infection. Among other important determinants, Ebola fusogenic glycoprotein (GP) has been associated with the detachment of infected cells and eventually leads to vascular leakage and haemorrhagic fever. Here we report that the membran...

journal_title：Nature communications

authors： Hacke M,Björkholm P,Hellwig A,Himmels P,Ruiz de Almodóvar C,Brügger B,Wieland F,Ernst AM

更新日期：2015-07-09 00:00:00

abstract：:Pulsars are rotating neutron stars emitting lighthouse-like beams. Owing to their unique properties, pulsars are a unique astrophysical tool to test general relativity, inform on matter in extreme conditions, and probe galactic magnetic fields. Understanding pulsar physics and emission mechanisms is critical to these ...

journal_title：Nature communications

authors： Gueroult R,Shi Y,Rax JM,Fisch NJ

更新日期：2019-07-19 00:00:00

abstract：:The long external filament of bacterial flagella is composed of several thousand copies of a single protein, flagellin. Here, we explore the role played by lysine methylation of flagellin in Salmonella, which requires the methylase FliB. We show that both flagellins of Salmonella enterica serovar Typhimurium, FliC and...

journal_title：Nature communications

authors： Horstmann JA,Lunelli M,Cazzola H,Heidemann J,Kühne C,Steffen P,Szefs S,Rossi C,Lokareddy RK,Wang C,Lemaire L,Hughes KT,Uetrecht C,Schlüter H,Grassl GA,Stradal TEB,Rossez Y,Kolbe M,Erhardt M

更新日期：2020-04-24 00:00:00

abstract：:The original version of this Article contained an error in Fig. 4. In the lower part of the three gene circuit diagrams in panel b, the flat-headed arrow linking lambdaCI to the tetR promoter incorrectly pointed to the tetR gene body. This has now been corrected in the HTML and PDF versions of this Article. ...

journal_title：Nature communications

authors： Purcell O,Wang J,Siuti P,Lu TK

更新日期：2019-01-08 00:00:00

abstract：:The efficiencies of perovskite solar cells (PSCs) are now reaching such consistently high levels that scalable manufacturing at low cost is becoming critical. However, this remains challenging due to the expensive hole-transporting materials usually employed, and difficulties associated with the scalable deposition of...

journal_title：Nature communications

authors： Wu WQ,Wang Q,Fang Y,Shao Y,Tang S,Deng Y,Lu H,Liu Y,Li T,Yang Z,Gruverman A,Huang J

更新日期：2018-04-24 00:00:00

abstract：:The divalent carbene carbon centre in cyclic (alkyl)(amino)carbenes (CAACs) is known to exhibit transition-metal-like insertion into E-H σ-bonds (E = H, N, Si, B, P, C, O) with formation of new, strong C-E and C-H bonds. Although subsequent transformations of the products represent an attractive strategy for metal-fre...

journal_title：Nature communications

authors： Oldroyd NL,Chitnis SS,Annibale VT,Arz MI,Sparkes HA,Manners I

更新日期：2019-03-26 00:00:00