Publisher Correction: Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.


:In the original version of this Article, extraneous text not belonging to the Article was accidentally appended to the results section. This error has now been corrected in both the PDF and HTML versions of the Article.


Nat Commun


Nature communications


Zhu Y,Orre LM,Johansson HJ,Huss M,Boekel J,Vesterlund M,Fernandez-Woodbridge A,Branca RMM,Lehtiö J




Has Abstract


2018-05-08 00:00:00












  • Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

    abstract::The bacteria-derived clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are powerful tools for genome engineering. Recently, in addition to Cas protein engineering, the improvement of guide RNAs are also performed, contributing to broadening the research area of CRISPR-Cas9 systems. Here we ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Kweon J,Jang AH,Kim DE,Yang JW,Yoon M,Rim Shin H,Kim JS,Kim Y

    更新日期:2017-11-23 00:00:00

  • Amygdala lesions in rhesus macaques decrease attention to threat.

    abstract::Evidence from animal and human studies has suggested that the amygdala plays a role in detecting threat and in directing attention to the eyes. Nevertheless, there has been no systematic investigation of whether the amygdala specifically facilitates attention to the eyes or whether other features can also drive attent...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Dal Monte O,Costa VD,Noble PL,Murray EA,Averbeck BB

    更新日期:2015-12-14 00:00:00

  • Uranium transport in acidic brines under reducing conditions.

    abstract::The behavior of uranium in environments, ranging from those of natural systems responsible for the formation of uranium deposits to those of nuclear reactors providing 11% of the world's electricity, is governed by processes involving high-temperature aqueous solutions. It has been well documented that uranium is mobi...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Timofeev A,Migdisov AA,Williams-Jones AE,Roback R,Nelson AT,Xu H

    更新日期:2018-04-16 00:00:00

  • Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine.

    abstract::Aging is characterized by a chronic, low-grade inflammation, which is a major risk factor for cardiovascular diseases. It remains poorly understood whether pro-inflammatory factors released from non-cardiac tissues contribute to the non-autonomous regulation of age-related cardiac dysfunction. Here, we report that age...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Huang K,Miao T,Chang K,Kim J,Kang P,Jiang Q,Simmonds AJ,Di Cara F,Bai H

    更新日期:2020-06-10 00:00:00

  • Photocathode functionalized with a molecular cobalt catalyst for selective carbon dioxide reduction in water.

    abstract::Artificial photosynthesis is a vibrant field of research aiming at converting abundant, low energy molecules such as water, nitrogen or carbon dioxide into fuels or useful chemicals by means of solar energy input. Photo-electrochemical reduction of carbon dioxide is an appealing strategy, aiming at reducing the greenh...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Pati PB,Wang R,Boutin E,Diring S,Jobic S,Barreau N,Odobel F,Robert M

    更新日期:2020-07-13 00:00:00

  • Publisher Correction: Encryption and steganography of synthetic gene circuits.

    abstract::The original version of this Article contained an error in Fig. 4. In the lower part of the three gene circuit diagrams in panel b, the flat-headed arrow linking lambdaCI to the tetR promoter incorrectly pointed to the tetR gene body. This has now been corrected in the HTML and PDF versions of this Article. ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误


    authors: Purcell O,Wang J,Siuti P,Lu TK

    更新日期:2019-01-08 00:00:00

  • Light-sensing via hydrogen peroxide and a peroxiredoxin.

    abstract::Yeast lacks dedicated photoreceptors; however, blue light still causes pronounced oscillations of the transcription factor Msn2 into and out of the nucleus. Here we show that this poorly understood phenomenon is initiated by a peroxisomal oxidase, which converts light into a hydrogen peroxide (H2O2) signal that is sen...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Bodvard K,Peeters K,Roger F,Romanov N,Igbaria A,Welkenhuysen N,Palais G,Reiter W,Toledano MB,Käll M,Molin M

    更新日期:2017-03-24 00:00:00

  • Fishing for newly synthesized proteins with phosphonate-handles.

    abstract::Bioorthogonal chemistry introduces affinity-labels into biomolecules with minimal disruption to the original system and is widely applicable in a range of contexts. In proteomics, immobilized metal affinity chromatography (IMAC) enables enrichment of phosphopeptides with extreme sensitivity and selectivity. Here, we a...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Kleinpenning F,Steigenberger B,Wu W,Heck AJR

    更新日期:2020-06-26 00:00:00

  • The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.

    abstract::Redox-regulated effector systems that counteract oxidative stress are essential for all forms of life. Here we uncover a new paradigm for sensing oxidative stress centred on the hydrophobic core of a sensor protein. RsrA is an archetypal zinc-binding anti-sigma factor that responds to disulfide stress in the cytoplasm...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Rajasekar KV,Zdanowski K,Yan J,Hopper JT,Francis ML,Seepersad C,Sharp C,Pecqueur L,Werner JM,Robinson CV,Mohammed S,Potts JR,Kleanthous C

    更新日期:2016-07-19 00:00:00

  • Sub-microWatt threshold nanoisland lasers.

    abstract::Ultralow threshold nanolasers have been sought after as power efficient light sources in photonic integrated circuits. Here a single-cell nanobeam laser with a nanoisland quantum well is proposed and demonstrated. Continuous operation at 1.5 μm is achieved at room temperature with an ultralow lasing threshold of 210 n...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Jang H,Karnadi I,Pramudita P,Song JH,Kim KS,Lee YH

    更新日期:2015-09-22 00:00:00

  • Durable and controlled depletion of neutrophils in mice.

    abstract::Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by injecting anti-Ly6G or anti-Gr1 antibodies. However, these approaches are only partially effective, transient or lack specificity. Here we report that neutrophil...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Boivin G,Faget J,Ancey PB,Gkasti A,Mussard J,Engblom C,Pfirschke C,Contat C,Pascual J,Vazquez J,Bendriss-Vermare N,Caux C,Vozenin MC,Pittet MJ,Gunzer M,Meylan E

    更新日期:2020-06-02 00:00:00

  • Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution.

    abstract::Biological tissues exhibit complex spatial heterogeneity that directs the functions of multicellular organisms. Quantifying protein expression is essential for elucidating processes within complex biological assemblies. Imaging mass spectrometry (IMS) is a powerful emerging tool for mapping the spatial distribution of...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Piehowski PD,Zhu Y,Bramer LM,Stratton KG,Zhao R,Orton DJ,Moore RJ,Yuan J,Mitchell HD,Gao Y,Webb-Robertson BM,Dey SK,Kelly RT,Burnum-Johnson KE

    更新日期:2020-01-07 00:00:00

  • Reconstructing propagation networks with natural diversity and identifying hidden sources.

    abstract::Our ability to uncover complex network structure and dynamics from data is fundamental to understanding and controlling collective dynamics in complex systems. Despite recent progress in this area, reconstructing networks with stochastic dynamical processes from limited time series remains to be an outstanding problem...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Shen Z,Wang WX,Fan Y,Di Z,Lai YC

    更新日期:2014-07-11 00:00:00

  • Closing the gap between palaeontological and neontological speciation and extinction rate estimates.

    abstract::Measuring the pace at which speciation and extinction occur is fundamental to understanding the origin and evolution of biodiversity. Both the fossil record and molecular phylogenies of living species can provide independent estimates of speciation and extinction rates, but often produce strikingly divergent results. ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Silvestro D,Warnock RCM,Gavryushkina A,Stadler T

    更新日期:2018-12-07 00:00:00

  • Atmospheric oxygen regulation at low Proterozoic levels by incomplete oxidative weathering of sedimentary organic carbon.

    abstract::It is unclear why atmospheric oxygen remained trapped at low levels for more than 1.5 billion years following the Paleoproterozoic Great Oxidation Event. Here, we use models for erosion, weathering and biogeochemical cycling to show that this can be explained by the tectonic recycling of previously accumulated sedimen...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Daines SJ,Mills BJ,Lenton TM

    更新日期:2017-02-02 00:00:00

  • VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8.

    abstract::The cation channel TRPM8 plays a central role in the somatosensory system, as a key sensor of innocuously cold temperatures and cooling agents. Although increased functional expression of TRPM8 has been implicated in various forms of pathological cold hypersensitivity, little is known about the cellular and molecular ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ghosh D,Pinto S,Danglot L,Vandewauw I,Segal A,Van Ranst N,Benoit M,Janssens A,Vennekens R,Vanden Berghe P,Galli T,Vriens J,Voets T

    更新日期:2016-02-04 00:00:00

  • A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.

    abstract::CD1 proteins are expressed on dendritic cells, where they display lipid antigens to T-cell receptors (TCRs). Here we describe T-cell autoreactivity towards ubiquitous human membrane phospholipids presented by CD1b. These T-cells discriminate between two major types of lipids, sphingolipids and phospholipids, but were ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Shahine A,Reinink P,Reijneveld JF,Gras S,Holzheimer M,Cheng TY,Minnaard AJ,Altman JD,Lenz S,Prandi J,Kubler-Kielb J,Moody DB,Rossjohn J,Van Rhijn I

    更新日期:2019-01-04 00:00:00

  • Active control of anapole states by structuring the phase-change alloy Ge2Sb2Te5.

    abstract::High-index dielectric nanoparticles supporting a distinct series of Mie resonances have enabled a new class of optical antennas with unprecedented functionalities. The great wealth of multipolar responses has not only brought in new physical insight but also spurred practical applications. However, how to make such a ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Tian J,Luo H,Yang Y,Ding F,Qu Y,Zhao D,Qiu M,Bozhevolnyi SI

    更新日期:2019-01-23 00:00:00

  • EPR-aided approach for solution structure determination of large RNAs or protein-RNA complexes.

    abstract::High-resolution structural information on RNA and its functionally important complexes with proteins is dramatically underrepresented compared with proteins but is urgently needed for understanding cellular processes at the molecular and atomic level. Here we present an EPR-based protocol to help solving large RNA and...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Duss O,Yulikov M,Jeschke G,Allain FH

    更新日期:2014-05-14 00:00:00

  • Aerodynamic generation of electric fields in turbulence laden with charged inertial particles.

    abstract::Self-induced electricity, including lightning, is often observed in dusty atmospheres. However, the physical mechanisms leading to this phenomenon remain elusive as they are remarkably challenging to determine due to the high complexity of the multi-phase turbulent flows involved. Using a fast multi-pole method in dir...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Di Renzo M,Urzay J

    更新日期:2018-04-26 00:00:00

  • Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation.

    abstract::X-chromosome inactivation (XCI), i.e., the inactivation of one of the female X chromosomes, restores equal expression of X-chromosomal genes between females and males. However, ~10% of genes show variable degrees of escape from XCI between females, although little is known about the causes of variable XCI. Using a dis...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Luijk R,Wu H,Ward-Caviness CK,Hannon E,Carnero-Montoro E,Min JL,Mandaviya P,Müller-Nurasyid M,Mei H,van der Maarel SM,BIOS Consortium.,Relton C,Mill J,Waldenberger M,Bell JT,Jansen R,Zhernakova A,Franke L,'t Hoen PAC

    更新日期:2018-09-14 00:00:00

  • Ultrafast electron cooling in an expanding ultracold plasma.

    abstract::Plasma dynamics critically depends on density and temperature, thus well-controlled experimental realizations are essential benchmarks for theoretical models. The formation of an ultracold plasma can be triggered by ionizing a tunable number of atoms in a micrometer-sized volume of a 87Rb Bose-Einstein condensate (BEC...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Kroker T,Großmann M,Sengstock K,Drescher M,Wessels-Staarmann P,Simonet J

    更新日期:2021-01-26 00:00:00

  • Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails.

    abstract::Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli. Here, we show that the d...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Dutertre S,Jin AH,Vetter I,Hamilton B,Sunagar K,Lavergne V,Dutertre V,Fry BG,Antunes A,Venter DJ,Alewood PF,Lewis RJ

    更新日期:2014-03-24 00:00:00

  • Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression.

    abstract::Recent developments in stem cell biology have enabled the study of cell fate decisions in early human development that are impossible to study in vivo. However, understanding how development varies across individuals and, in particular, the influence of common genetic variants during this process has not been characte...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Cuomo ASE,Seaton DD,McCarthy DJ,Martinez I,Bonder MJ,Garcia-Bernardo J,Amatya S,Madrigal P,Isaacson A,Buettner F,Knights A,Natarajan KN,HipSci Consortium.,Vallier L,Marioni JC,Chhatriwala M,Stegle O

    更新日期:2020-02-10 00:00:00

  • Designer photonic dynamics by using non-uniform electron temperature distribution for on-demand all-optical switching times.

    abstract::While free electrons in metals respond to ultrafast excitation with refractive index changes on femtosecond time scales, typical relaxation mechanisms occur over several picoseconds, governed by electron-phonon energy exchange rates. Here, we propose tailoring these intrinsic rates by engineering a non-uniform electro...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Nicholls LH,Stefaniuk T,Nasir ME,Rodríguez-Fortuño FJ,Wurtz GA,Zayats AV

    更新日期:2019-07-04 00:00:00

  • Export of a single drug molecule in two transport cycles by a multidrug efflux pump.

    abstract::Secondary multidrug transporters use ion concentration gradients to energize the removal from cells of various antibiotics. The Escherichia coli multidrug transporter MdfA exchanges a single proton with a single monovalent cationic drug molecule. This stoichiometry renders the efflux of divalent cationic drugs energet...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Fluman N,Adler J,Rotenberg SA,Brown MH,Bibi E

    更新日期:2014-08-08 00:00:00

  • Publisher Correction: Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division.

    abstract::The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误


    authors: Pazos M,Peters K,Casanova M,Palacios P,VanNieuwenhze M,Breukink E,Vicente M,Vollmer W

    更新日期:2019-01-30 00:00:00

  • Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids.

    abstract::Previous studies have utilized monoamine oxidase (MAO) and L-3,4-dihydroxyphenylalanine decarboxylase (DDC) for microbe-based production of tetrahydropapaveroline (THP), a benzylisoquinoline alkaloid (BIA) precursor to opioid analgesics. In the current study, a phylogenetically distinct Bombyx mori 3,4-dihydroxyphenyl...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Vavricka CJ,Yoshida T,Kuriya Y,Takahashi S,Ogawa T,Ono F,Agari K,Kiyota H,Li J,Ishii J,Tsuge K,Minami H,Araki M,Hasunuma T,Kondo A

    更新日期:2019-05-01 00:00:00

  • Integrated genetic and epigenetic analysis of myxofibrosarcoma.

    abstract::Myxofibrosarcoma (MFS) is a common adult soft tissue sarcoma characterized by an infiltrative growth pattern and a high local recurrence rate. Here we report the genetic and epigenetic landscape of MFS based on the results of whole-exome sequencing (N = 41), RNA sequencing (N = 29), and methylation analysis (N = 41), ...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Ogura K,Hosoda F,Arai Y,Nakamura H,Hama N,Totoki Y,Yoshida A,Nagai M,Kato M,Arakawa E,Mukai W,Rokutan H,Kawai A,Tanaka S,Shibata T

    更新日期:2018-07-17 00:00:00

  • An invariability-area relationship sheds new light on the spatial scaling of ecological stability.

    abstract::The spatial scaling of stability is key to understanding ecological sustainability across scales and the sensitivity of ecosystems to habitat destruction. Here we propose the invariability-area relationship (IAR) as a novel approach to investigate the spatial scaling of stability. The shape and slope of IAR are largel...

    journal_title:Nature communications

    pub_type: 杂志文章


    authors: Wang S,Loreau M,Arnoldi JF,Fang J,Rahman KA,Tao S,de Mazancourt C

    更新日期:2017-05-19 00:00:00