Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

abstract：:India is located at a critical geographic crossroads for understanding the dispersal of Homo sapiens out of Africa and into Asia and Oceania. Here we report evidence for long-term human occupation, spanning the last ~80 thousand years, at the site of Dhaba in the Middle Son River Valley of Central India. An unchanging...

journal_title：Nature communications

authors： Clarkson C,Harris C,Li B,Neudorf CM,Roberts RG,Lane C,Norman K,Pal J,Jones S,Shipton C,Koshy J,Gupta MC,Mishra DP,Dubey AK,Boivin N,Petraglia M

更新日期：2020-02-25 00:00:00

abstract：:The efficiency of an heat engine is traditionally defined as the ratio of its average output work over its average input heat. Its highest possible value was discovered by Carnot in 1824 and is a cornerstone concept in thermodynamics. It led to the discovery of the second law and to the definition of the Kelvin temper...

journal_title：Nature communications

authors： Verley G,Esposito M,Willaert T,Van den Broeck C

更新日期：2014-09-15 00:00:00

abstract：:Intense ultrashort X-ray pulses produced by modern free-electron lasers (FELs) allow one to probe biological systems, inorganic materials and molecular reaction dynamics with nanoscale spatial and femtoscale temporal resolution. These experiments require the knowledge, and possibly the control, of the spectro-temporal...

journal_title：Nature communications

authors： De Ninno G,Gauthier D,Mahieu B,Ribič PR,Allaria E,Cinquegrana P,Danailov MB,Demidovich A,Ferrari E,Giannessi L,Penco G,Sigalotti P,Stupar M

更新日期：2015-08-20 00:00:00

abstract：:Optimal decision-making employs short-term rewards and abstract long-term information based on which of these is deemed relevant. Employing short- vs. long-term information is associated with different learning mechanisms, yet neural evidence showing that these two are dissociable is lacking. Here we demonstrate that ...

journal_title：Nature communications

authors： Fischer AG,Bourgeois-Gironde S,Ullsperger M

更新日期：2017-11-22 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hayes MG,Urbanek M,Ehrmann DA,Armstrong LL,Lee JY,Sisk R,Karaderi T,Barber TM,McCarthy MI,Franks S,Lindgren CM,Welt CK,Diamanti-Kandarakis E,Panidis D,Goodarzi MO,Azziz R,Zhang Y,James RG,Olivier M,Kissebah AH,Rep

更新日期：2020-04-28 00:00:00

abstract：:In the original version of this Article, the legend in the upper panel of Figure 2 incorrectly read 'paternal imprinting' and should have read 'maternal imprinting'. This has been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Zeng Y,Amador C,Xia C,Marioni R,Sproul D,Walker RM,Morris SW,Bretherick A,Canela-Xandri O,Boutin TS,Clark DW,Campbell A,Rawlik K,Hayward C,Nagy R,Tenesa A,Porteous DJ,Wilson JF,Deary IJ,Evans KL,McIntosh AM,Nava

更新日期：2019-05-01 00:00:00

abstract：:Lithium metal is an ideal battery anode. However, dendrite growth and limited Coulombic efficiency during cycling have prevented its practical application in rechargeable batteries. Herein, we report that the use of highly concentrated electrolytes composed of ether solvents and the lithium bis(fluorosulfonyl)imide sa...

journal_title：Nature communications

authors： Qian J,Henderson WA,Xu W,Bhattacharya P,Engelhard M,Borodin O,Zhang JG

更新日期：2015-02-20 00:00:00

abstract：:Modern computation relies crucially on modular architectures, breaking a complex algorithm into self-contained subroutines. A client can then call upon a remote server to implement parts of the computation independently via an application programming interface (API). Present APIs relay only classical information. Here...

journal_title：Nature communications

authors： Zhang K,Thompson J,Zhang X,Shen Y,Lu Y,Zhang S,Ma J,Vedral V,Gu M,Kim K

更新日期：2019-10-16 00:00:00

abstract：:Recent outbreaks of Zika, chikungunya and dengue highlight the importance of better understanding the spread of disease-carrying mosquitoes across multiple spatio-temporal scales. Traditional surveillance tools are limited by jurisdictional boundaries and cost constraints. Here we show how a scalable citizen science s...

journal_title：Nature communications

authors： Palmer JRB,Oltra A,Collantes F,Delgado JA,Lucientes J,Delacour S,Bengoa M,Eritja R,Bartumeus F

更新日期：2017-10-24 00:00:00

abstract：:When two-dimensional crystals are brought into close proximity, their interaction results in reconstruction of electronic spectrum and crystal structure. Such reconstruction strongly depends on the twist angle between the crystals, which has received growing attention due to interesting electronic and optical properti...

journal_title：Nature communications

authors： Woods CR,Ares P,Nevison-Andrews H,Holwill MJ,Fabregas R,Guinea F,Geim AK,Novoselov KS,Walet NR,Fumagalli L

更新日期：2021-01-12 00:00:00

abstract：:A broad range of dynamic metasurfaces has been developed for manipulating the intensity, phase and wavefront of electromagnetic radiation from microwaves to optical frequencies. However, most of these metasurfaces operate in single-input-output state. Here, we experimentally demonstrate a reconfigurable MEMS Fano reso...

journal_title：Nature communications

authors： Manjappa M,Pitchappa P,Singh N,Wang N,Zheludev NI,Lee C,Singh R

更新日期：2018-10-03 00:00:00

abstract：:Runoff from the Greenland Ice Sheet (GrIS) is thought to enhance marine productivity by adding bioessential iron and silicic acid to coastal waters. However, experimental data suggest nitrate is the main summertime growth-limiting resource in regions affected by meltwater around Greenland. While meltwater contains low...

journal_title：Nature communications

authors： Hopwood MJ,Carroll D,Browning TJ,Meire L,Mortensen J,Krisch S,Achterberg EP

更新日期：2018-08-14 00:00:00

abstract：:The integration of nanophotonics and atomic physics has been a long-sought goal that would open new frontiers for optical physics, including novel quantum transport and many-body phenomena with photon-mediated atomic interactions. Reaching this goal requires surmounting diverse challenges in nanofabrication and atomic...

journal_title：Nature communications

authors： Goban A,Hung CL,Yu SP,Hood JD,Muniz JA,Lee JH,Martin MJ,McClung AC,Choi KS,Chang DE,Painter O,Kimble HJ

更新日期：2014-05-08 00:00:00

abstract：:Royal jelly is the queen-maker for the honey bee Apis mellifera, and has cross-species effects on longevity, fertility, and regeneration in mammals. Despite this knowledge, how royal jelly or its components exert their myriad effects has remained poorly understood. Using mouse embryonic stem cells as a platform, here ...

journal_title：Nature communications

authors： Wan DC,Morgan SL,Spencley AL,Mariano N,Chang EY,Shankar G,Luo Y,Li TH,Huh D,Huynh SK,Garcia JM,Dovey CM,Lumb J,Liu L,Brown KV,Bermudez A,Luong R,Zeng H,Mascetti VL,Pitteri SJ,Wang J,Tu H,Quarta M,Sebastiano

更新日期：2018-12-04 00:00:00

abstract：:Pulsars are rotating neutron stars emitting lighthouse-like beams. Owing to their unique properties, pulsars are a unique astrophysical tool to test general relativity, inform on matter in extreme conditions, and probe galactic magnetic fields. Understanding pulsar physics and emission mechanisms is critical to these ...

journal_title：Nature communications

authors： Gueroult R,Shi Y,Rax JM,Fisch NJ

更新日期：2019-07-19 00:00:00

abstract：:Although multiphoton-pumped lasing from a solution of chromophores is important in the emerging fields of nonlinear optofluidics and bio-photonics, conventionally used organic dyes are often rendered unsuitable because of relatively small multiphoton absorption cross-sections and low photostability. Here, we demonstra...

journal_title：Nature communications

authors： Li M,Zhi M,Zhu H,Wu WY,Xu QH,Jhon MH,Chan Y

更新日期：2015-09-30 00:00:00

abstract：:Cyclophanes are a venerable class of macrocyclic and/or cage compounds that often feature high strain, unusual conformations and quite surprising properties, many of which are legendary in physical organic chemistry. However, the discovery of new, diverse cyclophanes and derivatives has been hindered by syntheses that...

journal_title：Nature communications

authors： Collins MS,Carnes ME,Nell BP,Zakharov LN,Johnson DW

更新日期：2016-04-04 00:00:00

abstract：:Van der Waals (vdW) forces act ubiquitously in condensed matter. Despite being weak on an atomic level, they substantially influence molecular and biological systems due to their long range and system-size scaling. The difficulty to isolate and measure vdW forces on a single-molecule level causes our present understan...

journal_title：Nature communications

authors： Wagner C,Fournier N,Ruiz VG,Li C,Müllen K,Rohlfing M,Tkatchenko A,Temirov R,Tautz FS

更新日期：2014-11-26 00:00:00

abstract：:The identification of fractionalized excitations, such as Majorana quasi-particles, would be a striking signal of the realization of exotic quantum states of matter. While the paramount demonstration of such excitations would be a probe of their non-Abelian statistics via controlled braiding operations, alternative pr...

journal_title：Nature communications

authors： Laflamme C,Budich JC,Zoller P,Dalmonte M

更新日期：2016-08-02 00:00:00

abstract：:To cope with the global bacterial multidrug resistance, scientific communities have devoted significant efforts to develop novel antibiotics, particularly those with new modes of actions. Teixobactin, recently isolated from uncultured bacteria, is considered as a promising first-in-class drug candidate for clinical de...

journal_title：Nature communications

authors： Jin K,Sam IH,Po KHL,Lin D,Ghazvini Zadeh EH,Chen S,Yuan Y,Li X

更新日期：2016-08-03 00:00:00

abstract：:In two-dimensional interfacial assemblies, there is an interplay between molecular ordering and interface geometry, which determines the final morphology and order of entire systems. Here we present the interfacial phenomenon of spontaneous facet formation in a water droplet driven by designed peptide assembly. The id...

journal_title：Nature communications

authors： Jang HS,Lee JH,Park YS,Kim YO,Park J,Yang TY,Jin K,Lee J,Park S,You JM,Jeong KW,Shin A,Oh IS,Kwon MK,Kim YI,Cho HH,Han HN,Kim Y,Chang YH,Paik SR,Nam KT,Lee YS

更新日期：2014-04-11 00:00:00

abstract：:Elevated plasma cholesterol and type 2 diabetes (T2D) are associated with coronary artery disease (CAD). Individuals treated with cholesterol-lowering statins have increased T2D risk, while individuals with hypercholesterolemia have reduced T2D risk. We explore the relationship between lipid and glucose control by con...

journal_title：Nature communications

authors： Cohain AT,Barrington WT,Jordan DM,Beckmann ND,Argmann CA,Houten SM,Charney AW,Ermel R,Sukhavasi K,Franzen O,Koplev S,Whatling C,Belbin GM,Yang J,Hao K,Kenny EE,Tu Z,Zhu J,Gan LM,Do R,Giannarelli C,Kovacic JC,R

更新日期：2021-01-22 00:00:00

abstract：:Phonons are the main source of relaxation in molecular nanomagnets, and different mechanisms have been proposed in order to explain the wealth of experimental findings. However, very limited experimental investigations on phonons in these systems have been performed so far, yielding no information about their dispersi...

journal_title：Nature communications

authors： Garlatti E,Tesi L,Lunghi A,Atzori M,Voneshen DJ,Santini P,Sanvito S,Guidi T,Sessoli R,Carretta S

更新日期：2020-04-09 00:00:00

abstract：:UV vision is prevalent, but we know little about its utility in common general tasks, as in resolving habitat structure. Here we visualize vegetated habitats using a multispectral camera with channels mimicking bird photoreceptor sensitivities across the UV-visible spectrum. We find that the contrast between upper and...

journal_title：Nature communications

authors： Tedore C,Nilsson DE

更新日期：2019-01-22 00:00:00

abstract：:Ganglioside GM3, a host-derived glycosphingolipid incorporated in the membrane of human immunodeficiency virus-1 (HIV-1) viral particles, mediates interactions between HIV-1 and Siglec1/CD169, a protein expressed on dendritic cells (DCs). Such interactions, which seem to be independent of viral envelope glycoprotein g...

journal_title：Nature communications

authors： Yu X,Feizpour A,Ramirez NG,Wu L,Akiyama H,Xu F,Gummuluru S,Reinhard BM

更新日期：2014-06-20 00:00:00

abstract：:In the original version of this Article, equation three contained a sign error whereby the term RT was added when it should have been subtracted. This has now been corrected in the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Jung C,Bandilla P,von Reutern M,Schnepf M,Rieder S,Unnerstall U,Gaul U

更新日期：2019-02-05 00:00:00

abstract：:Caloric restriction (CR) without malnutrition increases longevity and delays the onset of age-associated disorders in short-lived species, from unicellular organisms to laboratory mice and rats. The value of CR as a tool to understand human ageing relies on translatability of CR's effects in primates. Here we show tha...

journal_title：Nature communications

authors： Colman RJ,Beasley TM,Kemnitz JW,Johnson SC,Weindruch R,Anderson RM

更新日期：2014-04-01 00:00:00

abstract：:Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and have the potential to exert forces several orders of magnitude larger than their optical counterpart at equivalent ...

journal_title：Nature communications

authors： Baudoin M,Thomas JL,Sahely RA,Gerbedoen JC,Gong Z,Sivery A,Matar OB,Smagin N,Favreau P,Vlandas A

更新日期：2020-08-25 00:00:00

abstract：:Capturing and controlling plasmons at buried interfaces with nanometre and femtosecond resolution has yet to be achieved and is critical for next generation plasmonic devices. Here we use light to excite plasmonic interference patterns at a buried metal-dielectric interface in a nanostructured thin film. Plasmons are ...

journal_title：Nature communications

authors： Lummen TTA,Lamb RJ,Berruto G,LaGrange T,Dal Negro L,García de Abajo FJ,McGrouther D,Barwick B,Carbone F

更新日期：2016-10-11 00:00:00

abstract：:G-quadruplexes (G4s) are noncanonical DNA structures that frequently occur in the promoter regions of oncogenes, such as MYC, and regulate gene expression. Although G4s are attractive therapeutic targets, ligands capable of discriminating between different G4 structures are rare. Here, we describe DC-34, a small molec...

journal_title：Nature communications

authors： Calabrese DR,Chen X,Leon EC,Gaikwad SM,Phyo Z,Hewitt WM,Alden S,Hilimire TA,He F,Michalowski AM,Simmons JK,Saunders LB,Zhang S,Connors D,Walters KJ,Mock BA,Schneekloth JS Jr

更新日期：2018-10-12 00:00:00