Towards optical polarization control of laser-driven proton acceleration in foils undergoing relativistic transparency.

abstract：:Emerging quantum technologies require mastering thermal management, especially at the nanoscale. It is now accepted that thermal metamaterial-based phonon manipulation is possible, especially at sub-kelvin temperatures. In these extreme limits of low temperatures and dimensions, heat conduction enters a quantum regime...

journal_title：Nature communications

authors： Tavakoli A,Lulla K,Crozes T,Mingo N,Collin E,Bourgeois O

更新日期：2018-10-16 00:00:00

abstract：:Chronic cranial window (CCW) is an essential tool in enabling longitudinal imaging and manipulation of various brain activities in live animals. However, an active CCW capable of sensing the concealed in vivo environment while simultaneously providing longitudinal optical access to the brain is not currently available...

journal_title：Nature communications

authors： Li H,Dong B,Zhang X,Shu X,Chen X,Hai R,Czaplewski DA,Zhang HF,Sun C

更新日期：2019-09-19 00:00:00

abstract：:Plasmodium parasites possess a translocon that exports parasite proteins into the infected erythrocyte. Although the translocon components are also expressed during the mosquito and liver stage of infection, their function remains unexplored. Here, using a combination of genetic and chemical assays, we show that the t...

journal_title：Nature communications

authors： Mello-Vieira J,Enguita FJ,de Koning-Ward TF,Zuzarte-Luís V,Mota MM

更新日期：2020-11-06 00:00:00

abstract：:Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer's disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As a result, it has proved difficult to identify optimal agents that target disease-relevant forms of Aβ. Here, we combined the u...

journal_title：Nature communications

authors： Jin M,O'Nuallain B,Hong W,Boyd J,Lagomarsino VN,O'Malley TT,Liu W,Vanderburg CR,Frosch MP,Young-Pearse T,Selkoe DJ,Walsh DM

更新日期：2018-07-11 00:00:00

abstract：:Understanding human cooperation is of major interest across the natural and social sciences. But it is unclear to what extent cooperation is actually a general concept. Most research on cooperation has implicitly assumed that a person's behaviour in one cooperative context is related to their behaviour in other settin...

journal_title：Nature communications

authors： Peysakhovich A,Nowak MA,Rand DG

更新日期：2014-09-16 00:00:00

abstract：:Two-component signal transduction systems consist of pairs of histidine kinases and response regulators, which mediate adaptive responses to environmental cues. Most activated response regulators regulate transcription by binding tightly to promoter DNA via a phosphorylation-triggered inactive-to-active transition. Th...

journal_title：Nature communications

authors： Narayanan A,Kumar S,Evrard AN,Paul LN,Yernool DA

更新日期：2014-01-01 00:00:00

abstract：:The temperature-jump technique, in which the sample is rapidly heated by a powerful laser pulse, has been widely used to probe the fast dynamics of folding of proteins and nucleic acids. However, the existing temperature-jump setups tend to involve sophisticated and expensive instrumentation, while providing only mode...

journal_title：Nature communications

authors： Polinkovsky ME,Gambin Y,Banerjee PR,Erickstad MJ,Groisman A,Deniz AA

更新日期：2014-12-17 00:00:00

abstract：:The two-dimensional topological insulators host a full gap in the bulk band, induced by spin-orbit coupling (SOC) effect, together with the topologically protected gapless edge states. However, it is usually challenging to suppress the bulk conductance and thus to realize the quantum spin Hall (QSH) effect. In this st...

journal_title：Nature communications

authors： Song YH,Jia ZY,Zhang D,Zhu XY,Shi ZQ,Wang H,Zhu L,Yuan QQ,Zhang H,Xing DY,Li SC

更新日期：2018-10-04 00:00:00

abstract：:The nucleotidyl cyclase toxin ExoY is one of the virulence factors injected by the Pseudomonas aeruginosa type III secretion system into host cells. Inside cells, it is activated by an unknown eukaryotic cofactor to synthesize various cyclic nucleotide monophosphates. ExoY-like adenylate cyclases are also found in Mul...

journal_title：Nature communications

authors： Belyy A,Raoux-Barbot D,Saveanu C,Namane A,Ogryzko V,Worpenberg L,David V,Henriot V,Fellous S,Merrifield C,Assayag E,Ladant D,Renault L,Mechold U

更新日期：2016-12-05 00:00:00

abstract：:The CCCTC-binding zinc-finger protein (CTCF)-mediated network of long-range chromatin interactions is important for genome organization and function. Although this network has been considered largely invariant, we find that it exhibits extensive cell-type-specific interactions that contribute to cell identity. Here, w...

journal_title：Nature communications

authors： Kai Y,Andricovich J,Zeng Z,Zhu J,Tzatsos A,Peng W

更新日期：2018-10-11 00:00:00

abstract：:The respiratory chain in mitochondria is composed of membrane-bound proteins that couple electron transfer to proton translocation across the inner membrane. These charge-transfer reactions are regulated by the proton electrochemical gradient that is generated and maintained by the transmembrane charge transfer. Here,...

journal_title：Nature communications

authors： Björck ML,Brzezinski P

更新日期：2018-08-09 00:00:00

abstract：:During apoptosis, Bak and Bax are activated by BH3-only proteins binding to the α2-α5 hydrophobic groove; Bax is also activated via a rear pocket. Here we report that antibodies can directly activate Bak and mitochondrial Bax by binding to the α1-α2 loop. A monoclonal antibody (clone 7D10) binds close to α1 in non-act...

journal_title：Nature communications

authors： Iyer S,Anwari K,Alsop AE,Yuen WS,Huang DC,Carroll J,Smith NA,Smith BJ,Dewson G,Kluck RM

更新日期：2016-05-24 00:00:00

abstract：:Solid substrates often induce non-uniform strain and doping in graphene monolayer, therefore altering the intrinsic properties of graphene, reducing its charge carrier mobilities and, consequently, the overall electrical performance. Here, we exploit confocal Raman spectroscopy to study graphene directly free-floating...

journal_title：Nature communications

authors： Belyaeva LA,Jiang L,Soleimani A,Methorst J,Risselada HJ,Schneider GF

更新日期：2020-02-14 00:00:00

abstract：:Herein, we report on a significant discovery, namely, the quantitative discharging of reduced graphite forms, such as graphite intercalation compounds, graphenide dispersions and graphenides deposited on surfaces with the simple solvent benzonitrile. Because of its comparatively low reduction potential, benzonitrile i...

journal_title：Nature communications

authors： Vecera P,Holzwarth J,Edelthalhammer KF,Mundloch U,Peterlik H,Hauke F,Hirsch A

更新日期：2016-08-10 00:00:00

abstract：:Pollinators tend to be preferentially attracted to large floral displays that may comprise more than one plant in a patch. Attracting pollinators thus not only benefits individuals investing in advertising, but also other plants in a patch through a 'magnet' effect. Accordingly, there could be an indirect fitness adva...

journal_title：Nature communications

authors： Torices R,Gómez JM,Pannell JR

更新日期：2018-05-22 00:00:00

abstract：:Bacterial CRISPR-Cas systems comprise diverse effector endonucleases with different targeting ranges, specificities and enzymatic properties, but many of them are inactive in mammalian cells and are thus precluded from genome-editing applications. Here we show that the type II-B FnCas9 from Francisella novicida posses...

journal_title：Nature communications

authors： Chen F,Ding X,Feng Y,Seebeck T,Jiang Y,Davis GD

更新日期：2017-04-07 00:00:00

abstract：:The advent of super-resolution imaging (SRI) has created a need for optimized labelling strategies. We present a new method relying on fluorophore-conjugated monomeric streptavidin (mSA) to label membrane proteins carrying a short, enzymatically biotinylated tag, compatible with SRI techniques including uPAINT, STED a...

journal_title：Nature communications

authors： Chamma I,Letellier M,Butler C,Tessier B,Lim KH,Gauthereau I,Choquet D,Sibarita JB,Park S,Sainlos M,Thoumine O

更新日期：2016-03-16 00:00:00

abstract：:Candida auris is an emerging fungal pathogen that exhibits resistance to multiple drugs, including the most commonly prescribed antifungal, fluconazole. Here, we use a combinatorial screening approach to identify a bis-benzodioxolylindolinone (azoffluxin) that synergizes with fluconazole against C. auris. Azoffluxin e...

journal_title：Nature communications

authors： Iyer KR,Camara K,Daniel-Ivad M,Trilles R,Pimentel-Elardo SM,Fossen JL,Marchillo K,Liu Z,Singh S,Muñoz JF,Kim SH,Porco JA Jr,Cuomo CA,Williams NS,Ibrahim AS,Edwards JE Jr,Andes DR,Nodwell JR,Brown LE,Whitesell L,Ro

更新日期：2020-12-22 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Fryirs KA,Brierley GJ,Dixon T

更新日期：2019-11-08 00:00:00

abstract：:Human endogenous retroviruses (HERV) form a substantial part of the human genome, but mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be reactivated by malignant transformation or epigenetic therapies. Here, we evaluate the potential for T cell recognition of HERV element...

journal_title：Nature communications

authors： Saini SK,Ørskov AD,Bjerregaard AM,Unnikrishnan A,Holmberg-Thydén S,Borch A,Jensen KV,Anande G,Bentzen AK,Marquard AM,Tamhane T,Treppendahl MB,Gang AO,Dufva IH,Szallasi Z,Ternette N,Pedersen AG,Eklund AC,Pimanda J,Gr

更新日期：2020-11-09 00:00:00

abstract：:Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reco...

journal_title：Nature communications

authors： Runge J,Petoukhov V,Donges JF,Hlinka J,Jajcay N,Vejmelka M,Hartman D,Marwan N,Paluš M,Kurths J

更新日期：2015-10-07 00:00:00

abstract：:The accumulation of protein aggregates is involved in the onset of many neurodegenerative diseases. Aggrephagy is a selective type of autophagy that counteracts neurodegeneration by degrading such aggregates. In this study, we found that LC3C cooperates with lysosomal TECPR1 to promote the degradation of disease-relat...

journal_title：Nature communications

authors： Wetzel L,Blanchard S,Rama S,Beier V,Kaufmann A,Wollert T

更新日期：2020-06-12 00:00:00

abstract：:Studying emerging or neglected pathogens is often challenging due to insufficient information and absence of genetic tools. Dual RNA-seq provides insights into host-pathogen interactions, and is particularly informative for intracellular organisms. Here we apply dual RNA-seq to Orientia tsutsugamushi (Ot), an obligate...

journal_title：Nature communications

authors： Mika-Gospodorz B,Giengkam S,Westermann AJ,Wongsantichon J,Kion-Crosby W,Chuenklin S,Wang LC,Sunyakumthorn P,Sobota RM,Subbian S,Vogel J,Barquist L,Salje J

更新日期：2020-07-03 00:00:00

abstract：:Surface charge density is the key factor for developing high performance triboelectric nanogenerators (TENG). The previously invented charge excitation TENG provides a most efficient way to achieve maximum charge output of a TENG device. Herein, criteria to quantitatively evaluate the contact efficiency and air breakd...

journal_title：Nature communications

authors： Liu Y,Liu W,Wang Z,He W,Tang Q,Xi Y,Wang X,Guo H,Hu C

更新日期：2020-03-27 00:00:00

abstract：:Designing highly durable and active electrocatalysts applied in polymer electrolyte membrane (PEM) electrolyzer for the oxygen evolution reaction remains a grand challenge due to the high dissolution of catalysts in acidic electrolyte. Hindering formation of oxygen vacancies by tuning the electronic structure of catal...

journal_title：Nature communications

authors： Hao S,Liu M,Pan J,Liu X,Tan X,Xu N,He Y,Lei L,Zhang X

更新日期：2020-10-23 00:00:00

abstract：:Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear malformations in hearing loss patients including Pendred syndrome. While biallelic mutations of the SLC26A4 gene, encoding pendrin, causes non-syndromic hearing loss with EVA or Pendred syndrome, a considerable number of patients appea...

journal_title：Nature communications

authors： Li M,Nishio SY,Naruse C,Riddell M,Sapski S,Katsuno T,Hikita T,Mizapourshafiyi F,Smith FM,Cooper LT,Lee MG,Asano M,Boettger T,Krueger M,Wietelmann A,Graumann J,Day BW,Boyd AW,Offermanns S,Kitajiri SI,Usami SI,Nak

更新日期：2020-03-12 00:00:00

abstract：:To overcome the fundamental challenge of the weak natural response of antiferromagnetic materials under a magnetic field, voltage manipulation of antiferromagnetic interaction is developed to realize ultrafast, high-density, and power efficient antiferromagnetic spintronics. Here, we report a low voltage modulation of...

journal_title：Nature communications

authors： Yang Q,Wang L,Zhou Z,Wang L,Zhang Y,Zhao S,Dong G,Cheng Y,Min T,Hu Z,Chen W,Xia K,Liu M

更新日期：2018-03-07 00:00:00

abstract：:Genomic alterations occurring during melanoma progression and the resulting genomic heterogeneity between metastatic deposits remain incompletely understood. Analyzing 86 metastatic melanoma deposits from 53 patients with whole-exome sequencing (WES), we show a low branch to trunk mutation ratio and little intermetast...

journal_title：Nature communications

authors： Birkeland E,Zhang S,Poduval D,Geisler J,Nakken S,Vodak D,Meza-Zepeda LA,Hovig E,Myklebost O,Knappskog S,Lønning PE

更新日期：2018-07-10 00:00:00

abstract：:Tyrosine sulfation, a well-characterized post-translation modification in eukaryotes, has not previously been reported in prokaryotes. Here, we demonstrate that the RaxST protein from the Gram-negative bacterium, Xanthomonas oryzae pv. oryzae, is a tyrosine sulfotransferase. We used a newly developed sulfotransferase ...

journal_title：Nature communications

authors： Han SW,Lee SW,Bahar O,Schwessinger B,Robinson MR,Shaw JB,Madsen JA,Brodbelt JS,Ronald PC

更新日期：2012-01-01 00:00:00

abstract：:Regulatory T (Treg) cells derived from the thymus (tTreg) and periphery (pTreg) have central and distinct functions in immunosuppression, but mechanisms for the generation and activation of Treg subsets in vivo are unclear. Here, we show that mechanistic target of rapamycin (mTOR) unexpectedly supports the homeostasis...

journal_title：Nature communications

authors： Chapman NM,Zeng H,Nguyen TM,Wang Y,Vogel P,Dhungana Y,Liu X,Neale G,Locasale JW,Chi H

更新日期：2018-05-29 00:00:00