Abstract:
:Tyrosine sulfation, a well-characterized post-translation modification in eukaryotes, has not previously been reported in prokaryotes. Here, we demonstrate that the RaxST protein from the Gram-negative bacterium, Xanthomonas oryzae pv. oryzae, is a tyrosine sulfotransferase. We used a newly developed sulfotransferase assay and ultraviolet photodissociation mass spectrometry to demonstrate that RaxST catalyses sulfation of tyrosine 22 of the Xoo Ax21 (activator of XA21-mediated immunity) protein. These results demonstrate a previously undescribed post-translational modification in a prokaryotic species with implications for studies of host immune responses and bacterial cell-cell communication systems.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Han SW,Lee SW,Bahar O,Schwessinger B,Robinson MR,Shaw JB,Madsen JA,Brodbelt JS,Ronald PCdoi
10.1038/ncomms2157subject
Has Abstractpub_date
2012-01-01 00:00:00pages
1153issn
2041-1723pii
ncomms2157journal_volume
3pub_type
杂志文章abstract::The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., once in 10...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05633-3
更新日期:2018-08-08 00:00:00
abstract::Synapse degeneration is an early and invariant feature of neurodegenerative diseases. Indeed, synapse loss occurs prior to neuronal degeneration and correlates with the symptom severity of these diseases. However, the molecular mechanisms that trigger synaptic loss remain poorly understood. Here we demonstrate that de...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5992
更新日期:2014-10-16 00:00:00
abstract::To learn, obtain reward and survive, humans and other animals must monitor, approach and act on objects that are associated with variable or unknown rewards. However, the neuronal mechanisms that mediate behaviours aimed at uncertain objects are poorly understood. Here we demonstrate that a set of neurons in an intern...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12735
更新日期:2016-09-14 00:00:00
abstract::Drought comprehensively affects different interlinked aspects of the terrestrial water cycle, which have so far been mostly investigated without direct comparison. Resolving the partitioning of water deficit during drought into blue-water runoff and green-water evapotranspiration fluxes is critical, as anomalies in th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06013-7
更新日期:2018-09-06 00:00:00
abstract::Lithium metal batteries have been considerably limited by the problems of uncontrolled dendritic lithium formation and the highly reactive nature of lithium with electrolytes. Herein, we have developed functional porous bilayer composite separators by simply blade-coating polyacrylamide-grafted graphene oxide molecula...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09211-z
更新日期:2019-03-25 00:00:00
abstract::Although many animals have evolved intrinsic transparency for the purpose of concealment, the development of dynamic, that is, controllable and reversible, transparency for living human cells and tissues has remained elusive to date. Here, by drawing inspiration from the structures and functionalities of adaptive ceph...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16151-6
更新日期:2020-06-02 00:00:00
abstract::FeV(O)(OH) species have long been proposed to play a key role in a wide range of biomimetic and enzymatic oxidations, including as intermediates in arene dihydroxylation catalyzed by Rieske oxygenases. However, the inability to accumulate these intermediates in solution has thus far prevented their spectroscopic and c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08668-2
更新日期:2019-02-22 00:00:00
abstract::Chiral magnets are an emerging class of topological matter harboring localized and topologically protected vortex-like magnetic textures called skyrmions, which are currently under intense scrutiny as an entity for information storage and processing. Here, on the level of micromagnetics we rigorously show that chiral ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00313-0
更新日期:2017-08-21 00:00:00
abstract::The ultrafast dynamics of hot carriers in graphene are key to both understanding of fundamental carrier-carrier interactions and carrier-phonon relaxation processes in two-dimensional materials, and understanding of the physics underlying novel high-speed electronic and optoelectronic devices. Many recent experiments ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11617
更新日期:2016-05-25 00:00:00
abstract::Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12413-0
更新日期:2019-09-25 00:00:00
abstract::The timely mobilization of hematopoietic stem and progenitor cells (HSPCs) is essential for maintaining hematopoietic and tissue leukocyte homeostasis. Understanding how HSPCs migrate between bone marrow (BM) and peripheral tissues is of great significance in the clinical setting, where therapeutic strategies for modu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11386-4
更新日期:2019-08-02 00:00:00
abstract::The demand for highly scalable, low-power devices for data storage and logic operations is strongly stimulating research into resistive switching as a novel concept for future non-volatile memory devices. To meet technological requirements, it is imperative to have a set of material design rules based on fundamental m...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9610
更新日期:2015-10-19 00:00:00
abstract::[This corrects the article DOI: 10.1038/ncomms5802.]. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/ncomms16177
更新日期:2017-11-29 00:00:00
abstract::High-resolution structural information on RNA and its functionally important complexes with proteins is dramatically underrepresented compared with proteins but is urgently needed for understanding cellular processes at the molecular and atomic level. Here we present an EPR-based protocol to help solving large RNA and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4669
更新日期:2014-05-14 00:00:00
abstract::Diatomic nitrogen is an archetypal molecular system known for its exceptional stability and complex behavior at high pressures and temperatures, including rich solid polymorphism, formation of energetic states, and an insulator-to-metal transformation coupled to a change in chemical bonding. However, the thermobaric c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05011-z
更新日期:2018-07-06 00:00:00
abstract::Strain engineering is widely used in material science to tune the (opto-)electronic properties of materials and enhance the performance of devices. Two-dimensional atomic crystals are a versatile playground to study the influence of strain, as they can sustain very large deformations without breaking. Various optical ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-02830-y
更新日期:2018-02-06 00:00:00
abstract::Invariant natural killer T cells have a distinct developmental pathway from conventional αβ T cells. Here we demonstrate that the transcriptional repressor NKAP is required for invariant natural killer T cell but not conventional T cell development. In CD4-cre NKAP conditional knockout mice, invariant natural killer T...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2580
更新日期:2013-01-01 00:00:00
abstract::Intermolecular halogen bonds are ideally suited for designing new molecular assemblies because of their strong directionality and the possibility of tuning the interactions by using different types of halogens or molecular moieties. Due to these unique properties of the halogen bonds, numerous areas of application hav...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19379-4
更新日期:2020-11-06 00:00:00
abstract::Early detection has the potential to reduce cancer mortality, but an effective screening test must demonstrate asymptomatic cancer detection years before conventional diagnosis in a longitudinal study. In the Taizhou Longitudinal Study (TZL), 123,115 healthy subjects provided plasma samples for long-term storage and w...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17316-z
更新日期:2020-07-21 00:00:00
abstract::As energy efficiency becomes a paramount issue in this day and age, reversible computing may serve as a critical step towards energy conservation in information technology. The inputs of reversible computing elements define the outputs and vice versa. Some reversible gates such as the Fredkin gate are also universal; ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11424
更新日期:2016-04-26 00:00:00
abstract::Detecting the metallic Dirac electronic states on the surface of Topological Insulators (TIs) is critical for the study of important surface quantum properties (SQPs), such as Majorana zero modes, where simultaneous probing of the bulk and edge electron states is required. However, there is a particular shortage of ex...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14838-4
更新日期:2020-03-09 00:00:00
abstract::Topological insulators do not allow conduction in the bulk, yet they support edge modes that travel along the boundary only in one direction, determined by the carried electron spin, with inherent robustness to defects and disorder. Topological insulators have inspired analogues in photonics and optics, in which one-w...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9260
更新日期:2015-10-06 00:00:00
abstract::Using mouse optic nerve (ON) crush as a CNS injury model, we and others have found that activation of the mammalian target of rapamycin complex 1 (mTORC1) in mature retinal ganglion cells by deletion of the negative regulators, phosphatase and tensin homologue (PTEN), and tuberous sclerosis 1 promotes ON regeneration....
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6416
更新日期:2014-11-10 00:00:00
abstract::Turning graphene magnetic is a promising challenge to make it an active material for spintronics. Predictions state that graphene structures with specific shapes can spontaneously develop magnetism driven by Coulomb repulsion of π-electrons, but its experimental verification is demanding. Here, we report on the observ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08060-6
更新日期:2019-01-14 00:00:00
abstract::The experimental investigation of quantum devices incorporating mechanical resonators has opened up new frontiers in the study of quantum mechanics at a macroscopic level. It has recently been shown that surface acoustic waves (SAWs) can be piezoelectrically coupled to superconducting qubits, and confined in high-qual...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01063-9
更新日期:2017-10-17 00:00:00
abstract::A 'pseudogap' was introduced by Mott to describe a state of matter that has a minimum in the density of states at the Fermi level, deep enough for states to become localized. It can arise either from Coulomb repulsion between electrons, and/or incipient charge or spin order. Here we employ ultrafast spectroscopy to st...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7958
更新日期:2015-04-20 00:00:00
abstract::Scleroderma is an autoimmune rheumatic disorder accompanied by severe fibrosis in skin and other internal organs. During scleroderma progression, resident fibroblasts undergo activation and convert to α-smooth muscle actin (α-SMA) expressing myofibroblasts (MFBs) with increased capacity to synthesize collagens and fib...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09101-4
更新日期:2019-03-08 00:00:00
abstract::Several of the steps in protein synthesis on the ribosome utilize hydrolysis of guanosine triphosphate (GTP) as the driving force. This reaction is catalyzed by translation factors that become activated upon binding to the ribosome. The recently determined crystal structure of an elongation factor-Tu ternary complex b...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2741
更新日期:2013-01-01 00:00:00
abstract::The complex transport processes contributing to sintering are not yet fully understood, partially because in-situ observations of sintering in three dimensions (3D) are very difficult. Here we report a novel experiment in which monocrystalline copper spheres are first marked with microscopic boreholes drilled using a ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1300
更新日期:2011-01-01 00:00:00
abstract::Aneuploidy and copy-number alterations (CNAs) are a hallmark of human cancer. Although genetically engineered mouse models (GEMMs) are commonly used to model human cancer, their chromosomal landscapes remain underexplored. Here we use gene expression profiles to infer CNAs in 3,108 samples from 45 mouse models, provid...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12160
更新日期:2016-07-04 00:00:00