Imbalance of Th17/Treg cells in pathogenesis of patients with human leukocyte antigen B27 associated acute anterior uveitis.

abstract：:HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed understandings of the molecular mechanisms underlying establishment and persistence of the reservoirs are needed. The cellular transcription factor KAP1 is known as a potent repre...

journal_title：Scientific reports

authors： Ait-Ammar A,Bellefroid M,Daouad F,Martinelli V,Van Assche J,Wallet C,Rodari A,De Rovere M,Fahrenkrog B,Schwartz C,Van Lint C,Gautier V,Rohr O

更新日期：2021-01-29 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transformed hepatocytes may ...

journal_title：Scientific reports

authors： Saito Y,Nakaoka T,Muramatsu T,Ojima H,Sukeda A,Sugiyama Y,Uchida R,Furukawa R,Kitahara A,Sato T,Kanai Y,Saito H

更新日期：2018-02-12 00:00:00

abstract：:The graphdiyne (GD), a carbon allotrope with a 2D structure comprising benzene rings and carbon-carbon triple bonds, can be synthesized through cross-coupling on the surface of copper foil. The key problem is in understanding the dependence of layers number and properties, however, the controlled growth of the layers ...

journal_title：Scientific reports

authors： Qian X,Liu H,Huang C,Chen S,Zhang L,Li Y,Wang J,Li Y

更新日期：2015-01-13 00:00:00

abstract：:The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, ...

journal_title：Scientific reports

authors： Turbé V,Gray ER,Lawson VE,Nastouli E,Brookes JC,Weiss RA,Pillay D,Emery VC,Verrips CT,Yatsuda H,Athey D,McKendry RA

更新日期：2017-09-20 00:00:00

abstract：:Green microalgae contain many active pigments such as carotenoids having antioxidant and protective activity on human cells. Here we investigate the biological activity of an ethanol/water extract of the marine green microalga Tetraselmis suecica containing high levels of carotenoids such as the xanthophylls lutein, v...

journal_title：Scientific reports

authors： Sansone C,Galasso C,Orefice I,Nuzzo G,Luongo E,Cutignano A,Romano G,Brunet C,Fontana A,Esposito F,Ianora A

更新日期：2017-01-24 00:00:00

abstract：:Several studies have shown that the human gaze, but not the robot gaze, has significant effects on infant social cognition and facilitate social engagement. The present study investigates early understanding of the referential nature of gaze by comparing-through the eye-tracking technique-infants' response to human an...

journal_title：Scientific reports

authors： Manzi F,Ishikawa M,Di Dio C,Itakura S,Kanda T,Ishiguro H,Massaro D,Marchetti A

更新日期：2020-07-17 00:00:00

abstract：:Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engineering. Extrusion-based 3D bioprinting necessitates a phase change from a liquid bioink to a semi-solid crosslinked network achieved by a photo-initiated free radical polymerization reaction that is known to be cytotox...

journal_title：Scientific reports

authors： Duchi S,Onofrillo C,O'Connell CD,Blanchard R,Augustine C,Quigley AF,Kapsa RMI,Pivonka P,Wallace G,Di Bella C,Choong PFM

更新日期：2017-07-19 00:00:00

abstract：:The extent to which the details of past experiences are retained or forgotten remains controversial. Some studies suggest massive storage while others describe memories as fallible summary recreations of original events. The discrepancy can be ascribed to the content of memories and how memories are evaluated. Many st...

journal_title：Scientific reports

authors： Misra P,Marconi A,Peterson M,Kreiman G

更新日期：2018-11-12 00:00:00

abstract：:After injury to the mature central nervous system (CNS), myelin-derived inhibitory ligands bind to the Nogo-66 tripartite receptor complex expressed on axonal growth cones, comprised of LINGO-1 and p75NTR/TROY and induce growth cone collapse through the RhoA pathway. We have also shown that amphoterin-induced gene and...

journal_title：Scientific reports

authors： Almutiri S,Berry M,Logan A,Ahmed Z

更新日期：2018-07-16 00:00:00

abstract：:One of the greatest challenges in the field of biofabrication remains the discovery of suitable bioinks that satisfy physicochemical and biological requirements. Despite recent advances in tissue engineering and biofabrication, progress has been limited to the development of technologies using polymer-based materials....

journal_title：Scientific reports

authors： Dessane B,Smirani R,Bouguéon G,Kauss T,Ribot E,Devillard R,Barthélémy P,Naveau A,Crauste-Manciet S

更新日期：2020-02-18 00:00:00

abstract：:Carbon fiber-synthetic foam core sandwich composites are widely used for many structural applications due to their superior mechanical performance and low weight. Unfortunately these structures typically have very poor acoustic performance. There is increasingly growing demand in mitigating this noise issue in sandwic...

journal_title：Scientific reports

authors： Sargianis J,Kim HI,Suhr J

更新日期：2012-01-01 00:00:00

abstract：:The primary hurdle for diagnosis of some diseases is the long incubation required to culture and confirm the presence of bacteria. The concept of using microbial VOCs as "signature markers" could provide a faster and noninvasive diagnosis. Finding biomarkers is challenging due to the specificity required in complex ma...

journal_title：Scientific reports

authors： Maurer DL,Ellis CK,Thacker TC,Rice S,Koziel JA,Nol P,VerCauteren KC

更新日期：2019-08-20 00:00:00

abstract：:In photosynthesis Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyses the often rate limiting CO2-fixation step in the Calvin cycle. This makes Rubisco both the gatekeeper for carbon entry into the biosphere and a target for functional improvement to enhance photosynthesis and plant growth. Encumbering...

journal_title：Scientific reports

authors： Wilson RH,Alonso H,Whitney SM

更新日期：2016-03-01 00:00:00

abstract：:The human sweet taste receptor (T1R2) monomer-a member of the G-protein coupled receptor family that detects a wide variety of chemically and structurally diverse sweet tasting molecules, is known to pose a significant threat to human health. Protein that lack crystal structure is a challenge in structure-based protei...

journal_title：Scientific reports

authors： Arodola OA,Kanchi S,Hloma P,Bisetty K,Asiri AM,Inamuddin

更新日期：2020-10-27 00:00:00

abstract：:The aim is to design a patient-specific instrument (PSI) for multilevel cervical pedicle screw placement from C2 to C7, as well as verifying reliability and reproducibility. Computed tomography (CT) scans were obtained from 7 cadaveric cervical spines. Using Mimics software, semiautomatic segmentation was performed fo...

journal_title：Scientific reports

authors： Sallent A,Ramírez M,Catalá J,Rodríguez-Baeza A,Bagó J,de Albert M,Vélez R

更新日期：2019-10-30 00:00:00

abstract：:Chaotic resonance is a phenomenon that can replace the fluctuation source in stochastic resonance from additive noise to chaos. We previously developed a method to control the chaotic state for suitably generating chaotic resonance by external feedback even when the external adjustment of chaos is difficult, establish...

journal_title：Scientific reports

authors： Nobukawa S,Shibata N,Nishimura H,Doho H,Wagatsuma N,Yamanishi T

更新日期：2019-09-02 00:00:00

abstract：:Hypoxia-inducible transcription factors (HIF) form heterodimeric complexes that mediate cell responses to hypoxia. The oxygen-dependent stability and activity of the HIF-α subunits is traditionally associated to post-translational modifications such as hydroxylation, acetylation, ubiquitination, and phosphorylation. H...

journal_title：Scientific reports

authors： Fala AM,Oliveira JF,Adamoski D,Aricetti JA,Dias MM,Dias MVB,Sforça ML,Lopes-de-Oliveira PS,Rocco SA,Caldana C,Dias SMG,Ambrosio ALB

更新日期：2015-08-03 00:00:00

abstract：:In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

journal_title：Scientific reports

authors： Arslan A,Sengul B

更新日期：2020-06-02 00:00:00

abstract：:Establishing robust genome engineering methods in the malarial parasite, Plasmodium falciparum, has the potential to substantially improve the efficiency with which we gain understanding of this pathogen's biology to propel treatment and elimination efforts. Methods for manipulating gene expression and engineering the...

journal_title：Scientific reports

authors： Nasamu AS,Falla A,Pasaje CFA,Wall BA,Wagner JC,Ganesan SM,Goldfless SJ,Niles JC

更新日期：2021-01-11 00:00:00

abstract：:Evidence showed preventive impacts of the highly active antiretroviral therapy (HAART) on the Human Immunodeficiency Virus (HIV) transmission amomg heterosexual population, however, that is of deficit among men who have sex with men (MSM). The aim was to systematically examine the efficacy of HAART on HIV transmission...

journal_title：Scientific reports

authors： Jiang Y,Su S,Borné Y

更新日期：2020-01-23 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease and a major health problem in the elderly population. No disease-modifying osteoarthritis drug (DMOAD) has been made available for clinical use. Here we present a disease-modifying strategy for OA, focusing on messenger RNA (mRNA) delivery of a therapeutic tr...

journal_title：Scientific reports

authors： Aini H,Itaka K,Fujisawa A,Uchida H,Uchida S,Fukushima S,Kataoka K,Saito T,Chung UI,Ohba S

更新日期：2016-01-05 00:00:00

abstract：:Irreversible electroporation (IRE) as a non-thermal tumor ablation technology has been studied for the treatment of pancreatic carcinoma and has shown a significant survival benefit. We discovered that moderate heating (MH) at 43 °C for 1-2 minutes significantly enhanced ex vivo IRE tumor ablation of Pan02 cells by 5....

journal_title：Scientific reports

authors： Edelblute CM,Hornef J,Burcus NI,Norman T,Beebe SJ,Schoenbach K,Heller R,Jiang C,Guo S

更新日期：2017-09-18 00:00:00

abstract：:Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...

journal_title：Scientific reports

authors： Aguiar AS Jr,Speck AE,Amaral IM,Canas PM,Cunha RA

更新日期：2018-07-16 00:00:00

abstract：:Quantitative reverse transcription PCR (RT-qPCR) is one of the most efficient, reliable and widely used techniques to quantify gene expression. In this study, we evaluated the performance of six southern corn rootworm, Diabrotica undecimpunctata howardi (Barber), housekeeping genes (HKG), β-actin (Actin), β-tubulin (T...

journal_title：Scientific reports

authors： Basu S,Pereira AE,Pinheiro DH,Wang H,Valencia-Jiménez A,Siegfried BD,Louis J,Zhou X',Vélez AM

更新日期：2019-07-24 00:00:00

abstract：:Fiber lasers with flexible spectral manipulation property could provide a flexible tool for scenes where the temporal coherence property accounts, for example, coherent sensing/communication and nonlinear frequency conversion. Due to the good laser performance and relative simplicity of implementation, random fiber la...

journal_title：Scientific reports

authors： Ye J,Xu J,Song J,Wu H,Zhang H,Wu J,Zhou P

更新日期：2018-02-01 00:00:00

abstract：:Telomere DNA ends with a single-stranded 3' overhang. Long 3' overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated several important players in preventing 5' end hyper-resection, yet detailed knowled...

journal_title：Scientific reports

authors： Runnberg R,Narayanan S,Cohn M

更新日期：2017-08-18 00:00:00

abstract：:High-grade gliomas are the most aggressive malignant brain tumors. Accurate pre-operative prognosis for this cohort can lead to better treatment planning. Conventional survival prediction based on clinical information is subjective and could be inaccurate. Recent radiomics studies have shown better prognosis by using ...

journal_title：Scientific reports

authors： Nie D,Lu J,Zhang H,Adeli E,Wang J,Yu Z,Liu L,Wang Q,Wu J,Shen D

更新日期：2019-01-31 00:00:00

abstract：:Rust fungi are plant pathogens that secrete an arsenal of effector proteins interfering with plant functions and promoting parasitic infection. Effectors are often species-specific, evolve rapidly, and display low sequence similarities with known proteins. How rust fungal effectors function in host cells remains elusi...

journal_title：Scientific reports

authors： de Guillen K,Lorrain C,Tsan P,Barthe P,Petre B,Saveleva N,Rouhier N,Duplessis S,Padilla A,Hecker A

更新日期：2019-12-02 00:00:00

abstract：:Hormones and placental factors are thought to underlie the maternal immunological changes during pregnancy. However, as several intestinal microbiota are linked to immune modulations, we hypothesized that the intestinal microbiota are altered during pregnancy in favor of species associated with pregnancy associated im...

journal_title：Scientific reports

authors： Elderman M,Hugenholtz F,Belzer C,Boekschoten M,de Haan B,de Vos P,Faas M

更新日期：2018-07-03 00:00:00

abstract：:An accurate and efficient solution of the radiative transport equation is proposed for modeling the propagation of photons in the three-dimensional anisotropically scattering half-space medium. The exact refractive index mismatched boundary condition is considered and arbitrary rotationally invariant scattering functi...

journal_title：Scientific reports

authors： Liemert A,Kienle A

更新日期：2013-01-01 00:00:00