The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells.

abstract：:Variations in isotopic composition of water vapor in the atmosphere is an important indicator of the processes within the hydrological cycle. Isotopic signature of water vapor and precipitation can be helpful in partitioning evaporation and transpiration fluxes. It is well known that transpiration from forested region...

journal_title：Scientific reports

authors： Pradhan R,Singh N,Singh RP

更新日期：2019-12-09 00:00:00

abstract：:The tick receptor for outer surface protein A (TROSPA) is the only identified factor involved in tick gut colonization by various Borrelia species. TROSPA is localized in the gut epithelium and can recognize and bind the outer surface bacterial protein OspA via an unknown mechanism. Based on earlier reports and our la...

journal_title：Scientific reports

authors： Urbanowicz A,Lewandowski D,Szpotkowski K,Figlerowicz M

更新日期：2016-04-26 00:00:00

abstract：:The actinopterygians comprise nearly one-half of all extant vertebrate species and are very important for human well-being. However, the phylogenetic relationships among certain groups within the actinopterygians are still uncertain, and debates about these relationships have continued for a long time. Along with the ...

journal_title：Scientific reports

authors： Zou M,Guo B,Tao W,Arratia G,He S

更新日期：2012-01-01 00:00:00

abstract：:Microbiome analysis using metagenomic sequencing has revealed a vast microbial diversity associated with plants. Identifying the molecular functions associated with microbiome-plant interaction is a significant challenge concerning the development of microbiome-derived technologies applied to agriculture. An alternati...

journal_title：Scientific reports

authors： Armanhi JS,de Souza RS,de Araújo LM,Okura VK,Mieczkowski P,Imperial J,Arruda P

更新日期：2016-07-12 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Randall CJ,van Woesik R

更新日期：2018-03-19 00:00:00

abstract：:The synthetic cyclic hexapeptide cWFW (cyclo(RRRWFW)) has a rapid bactericidal activity against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has, however, remained elusive. In contrast to most antimicrobial peptides, cWFW neither permeabilizes the membrane nor translocates to the cytoplas...

journal_title：Scientific reports

authors： Scheinpflug K,Wenzel M,Krylova O,Bandow JE,Dathe M,Strahl H

更新日期：2017-03-09 00:00:00

abstract：:Nearly half of the world's population obtains its daily calories from rice grains, which lack or have insufficient levels of essential micronutrients. The deficiency of micronutrients vital for normal growth is a global health problem, and iron, zinc and vitamin A deficiencies are the most prevalent ones. We developed...

journal_title：Scientific reports

authors： Singh SP,Gruissem W,Bhullar NK

更新日期：2017-07-31 00:00:00

abstract：:Lactic acid bacteria (LAB) are the common probiotics. Here, we investigated the antiviral protective effects of heat-killed LAB strain Lactobacillus casei DK128 (DK128) on influenza viruses. Intranasal treatment of mice with DK128 conferred protection against different subtypes of influenza viruses by lessening weight...

journal_title：Scientific reports

authors： Jung YJ,Lee YT,Ngo VL,Cho YH,Ko EJ,Hong SM,Kim KH,Jang JH,Oh JS,Park MK,Kim CH,Sun J,Kang SM

更新日期：2017-12-12 00:00:00

abstract：:Anthracnose caused by Colletotrichum is one of the most severe diseases of Hevea brasiliensis. However, research on the diversity and geographical distribution of Colletotrichum remains limited in China. In this study, we investigated the phylogenetic diversity of Colletotrichum isolates associated with symptomatic ti...

journal_title：Scientific reports

authors： Liu X,Li B,Cai J,Zheng X,Feng Y,Huang G

更新日期：2018-07-11 00:00:00

abstract：:Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions. However, there are limited data regarding the pursuant feedback between p53 transactivation and thiamine homeostasis. Impairment i...

journal_title：Scientific reports

authors： Chornyy S,Parkhomenko Y,Chorna N

更新日期：2017-09-06 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a highly metastatic cancer that is consistently associated with Epstein-Barr virus (EBV) infection. In this study, we identify for the first time a role for monoamine oxidase A (MAOA) in NPC. MAOA is a mitochondrial enzyme that catalyzes oxidative deamination of neurotransmitters and ...

journal_title：Scientific reports

authors： Lee HM,Sia APE,Li L,Sathasivam HP,Chan MSA,Rajadurai P,Tsang CM,Tsao SW,Murray PG,Tao Q,Paterson IC,Yap LF

更新日期：2020-04-09 00:00:00

abstract：:Tom40 is an integral protein of the mitochondrial outer membrane, which as the central component of the Translocase of the Outer Membrane (TOM) complex forms a channel for protein import. We characterize the diffusion properties of individual Tom40 molecules fused to the photoconvertable fluorescent protein Dendra2 wi...

journal_title：Scientific reports

authors： Kuzmenko A,Tankov S,English BP,Tarassov I,Tenson T,Kamenski P,Elf J,Hauryliuk V

更新日期：2011-01-01 00:00:00

abstract：:Understanding the transmission patterns of African swine fever (ASF) among wild boar (Sus scrofa) is an issue of major interest, especially in the wake of the current ASF epidemic. Given the high stability of ASF-virus, there is concern about scavengers spreading infectious carcass material in the environment. Here, w...

journal_title：Scientific reports

authors： Probst C,Gethmann J,Amler S,Globig A,Knoll B,Conraths FJ

更新日期：2019-08-07 00:00:00

abstract：:Species are chronically exposed to ionizing radiation, a natural phenomenon which can be enhanced by human activities. The induced toxicity mechanisms still remain unclear and seem depending on the mode of exposure, i.e. acute and chronic. To better understand these phenomena, studies need to be conducted both at the ...

journal_title：Scientific reports

authors： Dubois C,Lecomte C,Ruys SPD,Kuzmic M,Della-Vedova C,Dubourg N,Galas S,Frelon S

更新日期：2018-07-27 00:00:00

abstract：:Fusarium head blight (FHB) is a devastating disease of wheat worldwide. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding. A pore-forming toxin-like (PFT) gene at Fhb1 was first cloned by map-based cloning and found to confer FHB resistance in wheat. Proteins often inter...

journal_title：Scientific reports

authors： He Y,Wu L,Liu X,Zhang X,Jiang P,Ma H

更新日期：2019-10-29 00:00:00

abstract：:In this paper, phosphorene nanoribbons (PNRs) are theoretically studied using a multiscale simulation flow from the ab initio level to the tight binding (TB) level. The scaling effects of both armchair PNRs (aPNRs) and zigzag PNRs (zPNRs) from material properties to device properties are explored. The much larger effe...

journal_title：Scientific reports

authors： Lv Y,Chang S,Huang Q,Wang H,He J

更新日期：2016-11-29 00:00:00

abstract：:B-cell receptor (BCR) signaling plays a critical role in B-cell activation and humoral immunity. In this study, we discovered a critical function of leucine-rich repeat kinase 1 (LRRK1) in BCR-mediated immune responses. Lrrk1(-/-) mice exhibited altered B1a-cell development and basal immunoglobulin production. In addi...

journal_title：Scientific reports

authors： Morimoto K,Baba Y,Shinohara H,Kang S,Nojima S,Kimura T,Ito D,Yoshida Y,Maeda Y,Sarashina-Kida H,Nishide M,Hosokawa T,Kato Y,Hayama Y,Kinehara Y,Okuno T,Takamatsu H,Hirano T,Shima Y,Narazaki M,Kurosaki T,Toyofuku

更新日期：2016-05-11 00:00:00

abstract：:The blood brain barrier (BBB) is often an insurmountable obstacle for a large number of candidate drugs, including peptides, antibiotics, and chemotherapeutic agents. Devising an adroit delivery method to cross the BBB is essential to unlocking widespread application of peptide therapeutics. Presented here is an engin...

journal_title：Scientific reports

authors： Anand P,O'Neil A,Lin E,Douglas T,Holford M

更新日期：2015-08-03 00:00:00

abstract：:Engineering of efflux pumps is a promising way to improve host's tolerance to biofuels such as medium-chain alcohols (CmOHs); however, this strategy is restricted by poor understanding of the efflux pumps engaged in extrusion of solvents. In this study, several Escherichia coli mutants of multidrug transporters were e...

journal_title：Scientific reports

authors： Wang C,Yang L,Shah AA,Choi ES,Kim SW

更新日期：2015-11-13 00:00:00

abstract：:Liquid biopsy can provide a strong basis for precision medicine. We aimed to identify novel single-nucleotide variants (SNVs) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Deep sequencing of plasma-derived ctDNA from 59 patients with HCC was performed using a panel of 2924 SNVs in 6...

journal_title：Scientific reports

authors： Kim SS,Eun JW,Choi JH,Woo HG,Cho HJ,Ahn HR,Suh CW,Baek GO,Cho SW,Cheong JY

更新日期：2020-10-20 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models. Inherent challenges, however, are the pluripotency of IVIG and its xenogeneicity in animals. IVIG can alter the viability of human neutrophils v...

journal_title：Scientific reports

authors： Schneider C,Wicki S,Graeter S,Timcheva TM,Keller CW,Quast I,Leontyev D,Djoumerska-Alexieva IK,Käsermann F,Jakob SM,Dimitrova PA,Branch DR,Cummings RD,Lünemann JD,Kaufmann T,Simon HU,von Gunten S

更新日期：2017-05-02 00:00:00

abstract：:The combined regulation of a network of inhibitory and activating T cell receptors may be a critical step in the development of chronic HCV infection. Ex vivo HCV MHC class I + II tetramer staining and bead-enrichment was performed with baseline and longitudinal PBMC samples of a cohort of patients with acute, chronic...

journal_title：Scientific reports

authors： Ackermann C,Smits M,Woost R,Eberhard JM,Peine S,Kummer S,Marget M,Kuntzen T,Kwok WW,Lohse AW,Jacobs T,Boettler T,Schulze Zur Wiesch J

更新日期：2019-07-23 00:00:00

abstract：:Various treatment methods for tracheal defects have been attempted, such as artificial implants, allografts, autogenous grafts, and tissue engineering; however, no perfect method has been established. We attempted to create an effective artificial trachea via a tissue engineering method using 3D bio-printing. A multi-...

journal_title：Scientific reports

authors： Park JH,Yoon JK,Lee JB,Shin YM,Lee KW,Bae SW,Lee J,Yu J,Jung CR,Youn YN,Kim HY,Kim DH

更新日期：2019-02-14 00:00:00

abstract：:Cross-linked protein crystals (CLPCs) are very useful materials in applications such as biosensors, catalysis, and X-ray crystallography. Hence, preparation of CLPCs is an important research direction. During the preparation of CLPCs, an often encountered problem is that cracks may appear in the crystals, which may fi...

journal_title：Scientific reports

authors： Yan EK,Lu QQ,Zhang CY,Liu YL,He J,Chen D,Wang B,Zhou RB,Wu P,Yin DC

更新日期：2016-10-05 00:00:00

abstract：:In this work, a novel technique to create positive-negative tunable liquid crystal lenses is proposed and experimentally demonstrated. This structure is based on two main elements, a transmission line acting as a voltage divider and concentric electrodes that distribute the voltage homogeneously across the active area...

journal_title：Scientific reports

authors： Algorri JF,Morawiak P,Bennis N,Zografopoulos DC,Urruchi V,Rodríguez-Cobo L,Jaroszewicz LR,Sánchez-Pena JM,López-Higuera JM

更新日期：2020-06-23 00:00:00

abstract：:Emerging evidence suggests that the mammalian target of rapamcyin (mTOR) pathway is associated with radio-resistance in cancer treatment. We hypothesised that phosphorylated ribosomal S6 kinase 1 (p-S6K1), a major downstream regulator of the mTOR pathway, may play a role in predicting radio-resistance. Therefore, we e...

journal_title：Scientific reports

authors： Choi J,Yoon YN,Kim N,Park CS,Seol H,Park IC,Kim HA,Noh WC,Kim JS,Seong MK

更新日期：2020-01-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Houba T,Dasgupta A,Gopalakrishnan S,Gosse R,Roy S

更新日期：2020-01-21 00:00:00

abstract：:Reducing black carbon (BC), i.e. soot, in the atmosphere is a potential mitigation measure for climate change before revealing the effect of reducing anthropogenic carbon dioxide (CO2) because BC with shorter lifetime than CO2 absorbs solar and infrared radiation. BC has a strong positive radiative forcing in the atmo...

journal_title：Scientific reports

authors： Takemura T,Suzuki K

更新日期：2019-03-14 00:00:00

abstract：:The glycocalyx regulates the interaction of mammalian cells with extracellular molecules, such as cytokines. However, it is unknown to which extend the glycocalyx of distinct cancer cells control the binding and uptake of nanoparticles. In the present study, exome sequencing data of cancer patients and analysis of dis...

journal_title：Scientific reports

authors： von Palubitzki L,Wang Y,Hoffmann S,Vidal-Y-Sy S,Zobiak B,Failla AV,Schmage P,John A,Osorio-Madrazo A,Bauer AT,Schneider SW,Goycoolea FM,Gorzelanny C

更新日期：2020-12-31 00:00:00

abstract：:Excessive Zn2+ causes brain damage via promoting ROS generation. Here we investigated the role of ROS-sensitive TRPM2 channel in H2O2/Zn2+-induced Ca2+ signalling and cell death in microglial cells. H2O2/Zn2+ induced concentration-dependent increases in cytosolic Ca2+ concentration ([Ca2+]c), which was inhibited by PJ...

journal_title：Scientific reports

authors： Mortadza SS,Sim JA,Stacey M,Jiang LH

更新日期：2017-03-21 00:00:00