IVIG regulates the survival of human but not mouse neutrophils.

abstract：:It is well established that CD8(+) T cells play an important role in protective immunity against protozoan infections. However, their role in the course of Neospora caninum infection has not been fully elucidated. Here we report that CD8-deficient mice infected with N. caninum presented higher parasitic loads in the b...

journal_title：Scientific reports

authors： Correia A,Ferreirinha P,Botelho S,Belinha A,Leitão C,Caramalho Í,Teixeira L,González-Fernandéz Á,Appelberg R,Vilanova M

更新日期：2015-10-09 00:00:00

abstract：:The competitive multi-armed bandit (CMAB) problem is related to social issues such as maximizing total social benefits while preserving equality among individuals by overcoming conflicts between individual decisions, which could seriously decrease social benefits. The study described herein provides experimental evide...

journal_title：Scientific reports

authors： Chauvet N,Jegouso D,Boulanger B,Saigo H,Okamura K,Hori H,Drezet A,Huant S,Bachelier G,Naruse M

更新日期：2019-08-22 00:00:00

abstract：:Rhegmatogenous retinal detachment (RRD) is an ophthalmic emergency, which usually requires prompt surgery to prevent further detachment and restore sensory function. Although several individual factors have been suggested, a systems level understanding of molecular pathomechanisms underlying this severe eye disorder i...

journal_title：Scientific reports

authors： Öhman T,Gawriyski L,Miettinen S,Varjosalo M,Loukovaara S

更新日期：2021-01-13 00:00:00

abstract：:We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (>3 months) of the patients by analyzing free-text clinical notes in the electronic medical record, while maintaining the temporal visit sequence. In a si...

journal_title：Scientific reports

authors： Banerjee I,Gensheimer MF,Wood DJ,Henry S,Aggarwal S,Chang DT,Rubin DL

更新日期：2018-07-03 00:00:00

abstract：:Milk oligosaccharides (MOs) are complex carbohydrates with multifunctional health benefits for the neonate. Poor reproductive performance in primiparous gilts limits their productivity. Changes in the structure and abundance of porcine MO (PMOs) through lactation with parity remains unknown and may explain superior ne...

journal_title：Scientific reports

authors： Wei J,Wang ZA,Wang B,Jahan M,Wang Z,Wynn PC,Du Y

更新日期：2018-03-16 00:00:00

abstract：:Activation of different slip systems in hexagonal close packed (h.c.p.) metals depends primarily on the c/a ratio, which is an intrinsic property that can be altered through alloying addition. In conventional h.c.p. alloys where there is no diffusion-less phase transformation and associated transformation volume chang...

journal_title：Scientific reports

authors： Sinha S,Nene SS,Frank M,Liu K,Agrawal P,Mishra RS

更新日期：2019-09-12 00:00:00

abstract：:Aging is a highly controlled biological process characterized by a progressive deterioration of various cellular activities. One of several hallmarks of aging describes a link to transcriptional alteration, suggesting that it may impact the steady-state mRNA levels. We analyzed the mRNA steady-state levels of polyCAG-...

journal_title：Scientific reports

authors： Adamla F,Ignatova Z

更新日期：2015-06-02 00:00:00

abstract：:Insulin signaling governs many processes including glucose homeostasis and metabolism, and is therapeutically used to treat hyperglycemia in diabetes. We demonstrated that insulin-induced Akt activation enhances the sensitivity to TGF-β by directing an increase in cell surface TGF-β receptors from a pool of intracellu...

journal_title：Scientific reports

authors： Budi EH,Hoffman S,Gao S,Zhang YE,Derynck R

更新日期：2019-11-18 00:00:00

abstract：:In optical modulation, the highest available modulation rate is basically limited to the GHz frequency range at best. This is because optical modulation is often performed using electro-optic or acousto-optic effects that require application of an external signal to solid-state nonlinear optical materials. Here we des...

journal_title：Scientific reports

authors： Zaitsu S,Izaki H,Tsuchiya T,Imasaka T

更新日期：2016-02-18 00:00:00

abstract：:Molecular dynamics (MD) simulations lasting 500 ns were performed in explicit water to investigate the effect of polarization on the binding of ligands to human α-thrombin based on the standard nonpolarizable AMBER force field and the quantum-derived polarized protein-specific charge (PPC). The PPC includes the electr...

journal_title：Scientific reports

authors： Duan LL,Feng GQ,Zhang QG

更新日期：2016-08-10 00:00:00

abstract：:Glycosyltransferases (GTs) are bidirectional biocatalysts catalyzing the glycosylation of diverse molecules. However, the extensive applications of GTs in glycosides formation are limited due to their requirements of expensive nucleotide diphosphate (NDP)-sugars or NDP as the substrates. Here, in an effort to characte...

journal_title：Scientific reports

authors： Yuan S,Yin S,Liu M,Kong JQ

更新日期：2018-04-12 00:00:00

abstract：:Promoter CpG methylation is a fundamental regulatory process of gene expression. TET proteins are active CpG demethylases converting 5-methylcytosine to 5-hydroxymethylcytosine, with loss of 5 hmC as an epigenetic hallmark of cancers, indicating critical roles of TET proteins in epigenetic tumorigenesis. Through analy...

journal_title：Scientific reports

authors： Li L,Li C,Mao H,Du Z,Chan WY,Murray P,Luo B,Chan AT,Mok TS,Chan FK,Ambinder RF,Tao Q

更新日期：2016-05-26 00:00:00

abstract：:Phelan-McDermid Syndrome (PMS), which is defined by a deletion within 22q13, demonstrates significant phenotypic variation. Given that six mitochondrial genes are located within 22q13, including complex I and IV genes, we hypothesize that mitochondrial complex activity abnormalities may explain phenotypic variation in...

journal_title：Scientific reports

authors： Frye RE,Cox D,Slattery J,Tippett M,Kahler S,Granpeesheh D,Damle S,Legido A,Goldenthal MJ

更新日期：2016-01-29 00:00:00

abstract：:Astragalus membranaceus (HUANG QI, HQ) is a kind of traditional Chinese medicine. Researchers have widely concerned its antitumor effect. At present, there is still a lack of research on the treatment of laryngeal cancer with HQ. In this study, we integrated data from the weighted gene co-expression network of larynge...

journal_title：Scientific reports

authors： Dong KF,Huo MQ,Sun HY,Li TK,Li D

更新日期：2020-07-07 00:00:00

abstract：:The protein interface is key to understand protein function, providing a vital insight on how proteins interact with each other and with other molecules. Over the years, many computational methods to compare protein structures were developed, yet evaluating interface similarity remains a very difficult task. Here, we ...

journal_title：Scientific reports

authors： Budowski-Tal I,Kolodny R,Mandel-Gutfreund Y

更新日期：2018-05-29 00:00:00

abstract：:SERS spectra excited at 785 nm of the bacteria Chlamydia trahomatis (elementary bodies, EB) and Neisseria gonorrheoae, the causative pathogens for the two most common sexually transmitted diseases (STD), chlamydia and gonorrhea, respectively, are reported. Although both are Gram-negative bacteria, the SERS signatures ...

journal_title：Scientific reports

authors： Chen Y,Premasiri WR,Ziegler LD

更新日期：2018-03-26 00:00:00

abstract：:The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades. Here, we investigated the role...

journal_title：Scientific reports

authors： Shi Y,Lai X,Ye L,Chen K,Cao Z,Gong W,Jin L,Wang C,Liu M,Liao Y,Wang JM,Zhou N

更新日期：2017-02-10 00:00:00

abstract：:Self-heating induced failure of graphene devices synthesized from both chemical vapor deposition (CVD) and epitaxial means is compared using a combination of infrared thermography and Raman imaging. Despite a larger thermal resistance, CVD devices dissipate >3x the amount of power before failure than their epitaxial c...

journal_title：Scientific reports

authors： Beechem TE,Shaffer RA,Nogan J,Ohta T,Hamilton AB,McDonald AE,Howell SW

更新日期：2016-06-09 00:00:00

abstract：:TiNb6O17 and TiNb2O7 were synthesized using a solid-state method. The techniques were used to assess the electrochemical performance and lithium diffusion kinetics of TiNb6O17 related to the unit cell volume with TiNb2O7. The charge-discharge curves and cyclic voltammetry revealed TiNb6O17 to have a similar redox pote...

journal_title：Scientific reports

authors： Lee YS,Ryu KS

更新日期：2017-11-30 00:00:00

abstract：:In April 2012 we carried out a 1-year hematological study on a population of wild Japanese monkeys inhabiting the forest area of Fukushima City. This area is located 70 km from the Fukushima Daiichi Nuclear Power Plant (NPP), which released a large amount of radioactive material into the environment following the Grea...

journal_title：Scientific reports

authors： Ochiai K,Hayama S,Nakiri S,Nakanishi S,Ishii N,Uno T,Kato T,Konno F,Kawamoto Y,Tsuchida S,Omi T

更新日期：2014-07-24 00:00:00

abstract：:All real networks are different, but many have some structural properties in common. There seems to be no consensus on what the most common properties are, but scale-free degree distributions, strong clustering, and community structure are frequently mentioned without question. Surprisingly, there exists no simple gen...

journal_title：Scientific reports

authors： Zuev K,Boguñá M,Bianconi G,Krioukov D

更新日期：2015-04-29 00:00:00

abstract：:The inactivation of pathogens in liquids has broad applications, ranging from water disinfection to food pasteurization. However, common cell inactivation methods (e.g., chlorination, ultraviolet radiation and thermal treatment) have significant drawbacks such as carcinogenic byproduct formation, energy intensiveness ...

journal_title：Scientific reports

authors： Huo ZY,Li GQ,Yu T,Feng C,Lu Y,Wu YH,Yu C,Xie X,Hu HY

更新日期：2018-10-25 00:00:00

abstract：:After nearly a century of vaccination and six decades of drug therapy, tuberculosis (TB) kills more people annually than any other infectious disease. Substantial challenges to disease eradication remain among vulnerable and underserved populations. The Guarani-Kaiowá people are an indigenous population in Paraguay an...

journal_title：Scientific reports

authors： Hadi SA,Kolte IV,Brenner EP,Cunha EAT,Simonsen V,Ferrazoli L,Villela DAM,Santos RS,Ravi J,Sreevatsan S,Basta PC

更新日期：2021-01-13 00:00:00

abstract：:Using Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), previous study showed significant gender differences for cognitive deficits in immediate and delayed memory in schizophrenia patients. However, RBANS does not include reasoning and problem solving, and social cognition. These cognitive f...

journal_title：Scientific reports

authors： Zhang B,Han M,Tan S,De Yang F,Tan Y,Jiang S,Zhang X,Huang XF

更新日期：2017-09-19 00:00:00

abstract：:In wild animal conservation, knowing the age of an individual animal is extremely beneficial. However, estimating the age is difficult for many species. Recently, epigenetics-based methods of estimating age have been reported. These studies were predominantly on humans with few reports on other animals, especially wil...

journal_title：Scientific reports

authors： Ito H,Udono T,Hirata S,Inoue-Murayama M

更新日期：2018-07-03 00:00:00

abstract：:Knee osteoarthritis (KOA) is reported to have characteristic kinematics during walking. However, the relationship between Kellgren-Lawrence (K/L) score and the 3D kinematic gait of patients with medial KOA remains unclear. Here, ninety-seven patients with medial KOA and thirty-eight asymptomatic participants were invo...

journal_title：Scientific reports

authors： Zeng X,Ma L,Lin Z,Huang W,Huang Z,Zhang Y,Mao C

更新日期：2017-06-22 00:00:00

abstract：:How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of seven genes that we...

journal_title：Scientific reports

authors： Honda Y,Higashibata A,Matsunaga Y,Yonezawa Y,Kawano T,Higashitani A,Kuriyama K,Shimazu T,Tanaka M,Szewczyk NJ,Ishioka N,Honda S

更新日期：2012-01-01 00:00:00

abstract：:We describe a spin wave modulator - spintronic device aimed to control spin wave propagation by an electric field. The modulator consists of a ferromagnetic film serving as a spin wave bus combined with a synthetic multiferroic comprising piezoelectric and magnetostrictive materials. Its operation is based on the stre...

journal_title：Scientific reports

authors： Balinskiy M,Chavez AC,Barra A,Chiang H,Carman GP,Khitun A

更新日期：2018-07-18 00:00:00

abstract：:The aim of this study was to investigate the characteristics of insulin producing cells (IPCs) differentiated from adipose-tissue derived stem cells (ADSCs) isolated from human subcutaneous and visceral adipose tissues and identify ADSCs suitable for differentiation into efficient and functional IPCs. Subcutaneous and...

journal_title：Scientific reports

authors： Wada Y,Ikemoto T,Morine Y,Imura S,Saito Y,Yamada S,Shimada M

更新日期：2019-09-13 00:00:00

abstract：:Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA accumulation inhibits ...

journal_title：Scientific reports

authors： Digiovanni S,Visentin C,Degani G,Barbiroli A,Chiara M,Regazzoni L,Di Pisa F,Borchert AJ,Downs DM,Ricagno S,Vanoni MA,Popolo L

更新日期：2020-06-23 00:00:00