Preparation of cross-linked hen-egg white lysozyme crystals free of cracks.

abstract：:Therapeutic application of newly developed oximes is limited due to their adverse effects on different tissues. Within this article, it has been investigated which morphological changes could be observed in Wistar rats after the treatment with increasing doses of selected acetyl cholinesterase reactivators - asoxime, ...

journal_title：Scientific reports

authors： Jaćević V,Nepovimova E,Kuča K

更新日期：2019-02-06 00:00:00

abstract：:Radiomics has shown promise in improving models for predicting patient outcomes. However, to maximize the information gain of the radiomics features, especially in larger patient cohorts, the variability in radiomics features owing to differences between scanners and scanning protocols must be accounted for. To this a...

journal_title：Scientific reports

authors： Ger RB,Zhou S,Chi PM,Lee HJ,Layman RR,Jones AK,Goff DL,Fuller CD,Howell RM,Li H,Stafford RJ,Court LE,Mackin DS

更新日期：2018-08-29 00:00:00

abstract：:Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening and diagnosis. This labor-intensive task could greatly benefit from automatic detection usi...

journal_title：Scientific reports

authors： Sahlsten J,Jaskari J,Kivinen J,Turunen L,Jaanio E,Hietala K,Kaski K

更新日期：2019-07-24 00:00:00

abstract：:To better understand the effects of transient thermal stress in an aquatic insect, we first identified static temperatures associated with fitness deficits, and then reared larvae from egg hatch to adulthood under diurnally variable regimens including daily forays into deleterious temperatures. We sampled mature larva...

journal_title：Scientific reports

authors： Chou H,Jima DD,Funk DH,Jackson JK,Sweeney BW,Buchwalter DB

更新日期：2020-11-05 00:00:00

abstract：:Mitochondrial genomes exhibit diverse features among eukaryotes in the aspect of gene content, genome structure, and the mobile genetic elements such as introns and plasmids. Although the number of published mitochondrial genomes is increasing at tremendous speed, those of several lineages remain unexplored. Here, we ...

journal_title：Scientific reports

authors： Nishimura Y,Shiratori T,Ishida KI,Hashimoto T,Ohkuma M,Inagaki Y

更新日期：2019-03-19 00:00:00

abstract：:Thus far, underwater and underground positioning techniques have been limited to those using classical waves (sound waves, electromagnetic waves or their combination). However, the positioning accuracy is strongly affected by the conditions of media they propagate (temperature, salinity, density, elastic constants, op...

journal_title：Scientific reports

authors： Tanaka HKM

更新日期：2020-11-03 00:00:00

abstract：:Molecular taxonomy often uncovers cryptic species, reminding us that taxonomic incompleteness is even more severe than previous thought. The importance of cryptic species for conservation is poorly understood. Although some cryptic species may be seriously threatened or otherwise important, they are rarely included in...

journal_title：Scientific reports

authors： Delić T,Trontelj P,Rendoš M,Fišer C

更新日期：2017-06-13 00:00:00

abstract：:Ion pumps and channels are responsible for a wide variety of biological functions. Ion pumps transport only one ion during each stimulus-dependent reaction cycle, whereas ion channels conduct a large number of ions during each cycle. Ion pumping rhodopsins such as archaerhodopsin-3 (Arch) are often utilized as light-d...

journal_title：Scientific reports

authors： Yamanashi T,Maki M,Kojima K,Shibukawa A,Tsukamoto T,Chowdhury S,Yamanaka A,Takagi S,Sudo Y

更新日期：2019-05-27 00:00:00

abstract：:The interlocking roles of lexical, syntactic and semantic processing in language comprehension has been the subject of longstanding debate. Recently, the cortical response to a frequency-tagged linguistic stimulus has been shown to track the rate of phrase and sentence, as well as syllable, presentation. This could be...

journal_title：Scientific reports

authors： Burroughs A,Kazanina N,Houghton C

更新日期：2021-01-28 00:00:00

abstract：:In this work, we apply homodyne detection to investigate the frequency-resolved photon statistics of a cw light field emitted by a driven-dissipative semiconductor system in real time. We demonstrate that studying the frequency dependence of the photon number noise allows us to distinguish intrinsic noise properties o...

journal_title：Scientific reports

authors： Lüders C,Aßmann M

更新日期：2020-12-29 00:00:00

abstract：:The mechanism of immune tolerance is to be further understood. The present study aims to investigate the role of the Cardiac endothelial cell (CEC)-derived exosomes in the induction of regulatory B cells. In this study, CECs were isolated from the mouse heart. Exosomes were purified from the culture supernatant of the...

journal_title：Scientific reports

authors： Song J,Chen X,Wang M,Xing Y,Zheng Z,Hu S

更新日期：2014-12-23 00:00:00

abstract：:Using the universal structure predictor algorithm, we proposed that two-dimensional MnB structures with p4mmm (α-MnB) and pmma (β-MnB) symmetries could be synthesized. This finding was verified by calculating the dynamical stability, molecular dynamics, and mechanical properties. The α-MnB had an in-plane stiffness Y ...

journal_title：Scientific reports

authors： Farooq MU,Hashmi A,Khan I,Hong J

更新日期：2017-12-06 00:00:00

abstract：:Radiotherapy (RT) is one of the most frequently used methods for cancer treatment. Despite remarkable advancements in RT techniquesthe treatment of radioresistant tumours (i.e. high-grade gliomas) is not yet satisfactory. Finding novel approaches less damaging for normal tissues is of utmost importance. This would mak...

journal_title：Scientific reports

authors： Lamirault C,Doyère V,Juchaux M,Pouzoulet F,Labiod D,Dendale R,Patriarca A,Nauraye C,Le Dudal M,Jouvion G,Hardy D,Massioui NE,Prezado Y

更新日期：2020-08-11 00:00:00

abstract：:Determining oil migration distances from source rocks to reservoirs can greatly help in the search for new petroleum accumulations. Concentrations and ratios of polar organic compounds are known to change due to preferential sorption of these compounds in migrating oils onto immobile mineral surfaces. However, these c...

journal_title：Scientific reports

authors： Zhang L,Li M,Wang Y,Yin QZ,Zhang W

更新日期：2013-01-01 00:00:00

abstract：:Because of its multifactorial nature, predicting the presence of cancer using a single biomarker is difficult. We aimed to establish a novel machine-learning model for predicting hepatocellular carcinoma (HCC) using real-world data obtained during clinical practice. To establish a predictive model, we developed a mach...

journal_title：Scientific reports

authors： Sato M,Morimoto K,Kajihara S,Tateishi R,Shiina S,Koike K,Yatomi Y

更新日期：2019-05-30 00:00:00

abstract：:We have studied differentially regulated nuclear proteome of the clinical tissue specimens of glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using high resolution mass spectrometry- based quantitative proteomics approach. The results showed altered expression of many regulatory protein...

journal_title：Scientific reports

authors： Gupta MK,Polisetty RV,Sharma R,Ganesh RA,Gowda H,Purohit AK,Ankathi P,Prasad K,Mariswamappa K,Lakshmikantha A,Uppin MS,Sundaram C,Gautam P,Sirdeshmukh R

更新日期：2019-07-29 00:00:00

abstract：:The S385Y/D469T/R520Q variant of E. coli transketolase was evolved previously with three successive smart libraries, each guided by different structural, bioinformatical or computational methods. Substrate-walking progressively shifted the target acceptor substrate from phosphorylated aldehydes, towards a non-phosphor...

journal_title：Scientific reports

authors： Affaticati PE,Dai SB,Payongsri P,Hailes HC,Tittmann K,Dalby PA

更新日期：2016-10-21 00:00:00

abstract：:The effects of gradual vascular occlusion on the blood supply of perfused areas are poorly described. Information relating to the comparison of flap monitoring techniques is lacking. Varying stenotic conditions (0%, 25%, 50%, 75% and 100%) were generated on purpose at the A. and V. femoralis in the rat model. Analyses...

journal_title：Scientific reports

authors： Mücke T,Hapfelmeier A,Schmidt LH,Fichter AM,Kanatas A,Wolff KD,Ritschl LM

更新日期：2020-01-22 00:00:00

abstract：:Staphylococcus lugdunensis is a commensal bacterium in humans and other animals that can cause serious infections. The aim of this research was to estimate the frequency of S. lugdunensis in pet cats and to characterize the S. lugdunensis isolates obtained. The prevalence of S. lugdunensis was 0.77% (4/523) in healthy...

journal_title：Scientific reports

authors： Bierowiec K

更新日期：2020-09-22 00:00:00

abstract：:We assessed 1-year outcomes in patients with atrial fibrillation enrolled in the EurObservational Research Programme AF General Pilot Registry (EORP-AF), in relation to kidney function, as assessed by glomerular filtration rate (eGFR). In a cohort of 2398 patients (median age 69 years; 61% male), eGFR (ml/min/1.73 m(2...

journal_title：Scientific reports

authors： Boriani G,Laroche C,Diemberger I,Popescu MI,Rasmussen LH,Petrescu L,Crijns HJGM,Tavazzi L,Maggioni AP,Lip GYH

更新日期：2016-07-28 00:00:00

abstract：:The development of bulk, three-dimensional (3D), macroporous polymers with high permeability, large surface area and large volume is highly desirable for a range of applications in the biomedical, biotechnological and environmental areas. The experimental techniques currently used are limited to the production of smal...

journal_title：Scientific reports

authors： Savina IN,Ingavle GC,Cundy AB,Mikhalovsky SV

更新日期：2016-02-17 00:00:00

abstract：:Saliva, as a non-invasive and easily accessible biofluid, has been shown to contain RNA biomarkers for prediction and diagnosis of several diseases. However, systematic analysis done by our group identified two problematic issues not coherently described before: (1) most of the isolated RNA originates from the oral mi...

journal_title：Scientific reports

authors： Ostheim P,Tichý A,Sirak I,Davidkova M,Stastna MM,Kultova G,Paunesku T,Woloschak G,Majewski M,Port M,Abend M

更新日期：2020-07-07 00:00:00

abstract：:Interferometry-based online partial discharge (PD) monitor presented in this paper can detect the occurrence of PD sensitively, evaluate the peak value of the discharge inception voltage with random waveform and the damage extent relatively cost effectively. The interferograms affected by the PD are collected online. ...

journal_title：Scientific reports

authors： Xue L,Zhu Y,Yang C,Kumarawadu S

更新日期：2020-11-04 00:00:00

abstract：:Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2017-06-16 00:00:00

abstract：:A wide range of human diseases is associated with mutations that, destabilizing proteins native state, promote their aggregation. However, the mechanisms leading from folded to aggregated states are still incompletely understood. To investigate these mechanisms, we used a combination of NMR spectroscopy and molecular ...

journal_title：Scientific reports

authors： Camilloni C,Sala BM,Sormanni P,Porcari R,Corazza A,De Rosa M,Zanini S,Barbiroli A,Esposito G,Bolognesi M,Bellotti V,Vendruscolo M,Ricagno S

更新日期：2016-05-06 00:00:00

abstract：:The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. We thus compared the levels of biliary and serum MIC-1 and conventional tumour markers between 23 biliary tract cancer (BTC) patients (malignant group) and 29 benign biliary disease patients (benign grou...

journal_title：Scientific reports

authors： Sugimoto M,Takagi T,Konno N,Suzuki R,Asama H,Watanabe K,Nakamura J,Waragai Y,Kikuchi H,Takasumi M,Sato Y,Hikichi T,Ohira H

更新日期：2017-08-23 00:00:00

abstract：:To obtain high performance CH3NH3PbI3 perovskite solar cells, it is highly important to realise a high open-circuit voltage. Calculation results based on a modified diode model have indicated that a low bare ratio ϕ of the perovskite film is the most important factor determining the open-circuit voltage, where ϕ is de...

journal_title：Scientific reports

authors： Li Y,Ding B,Chu QQ,Yang GJ,Wang M,Li CX,Li CJ

更新日期：2017-04-12 00:00:00

abstract：:Nonstoichiometric silicon nitride SiNx is a promising material for developing a new generation of high-speed, reliable flash memory device based on the resistive effect. The advantage of silicon nitride over other dielectrics is its compatibility with the silicon technology. In the present work, a silicon nitride-base...

journal_title：Scientific reports

authors： Gismatulin AA,Kamaev GN,Kruchinin VN,Gritsenko VA,Orlov OM,Chin A

更新日期：2021-01-28 00:00:00

abstract：:In the last forty years therapy outcomes for depression have remained the same with approximately 50% of patients responding to treatments. Advances are urgently required. We hypothesised that a recent treatment, metacognitive therapy (MCT), might be more effective, by targeting mental control processes that directly ...

journal_title：Scientific reports

authors： Callesen P,Reeves D,Heal C,Wells A

更新日期：2020-05-12 00:00:00

abstract：:Animals execute sensorimotor sequences to optimize performance of complex actions series. However, the sensory aspects of these sequences and their dynamic control are often poorly understood. We trained bats to fly to targets at different distances, and analysed their sensory behavior before and during flight to test...

journal_title：Scientific reports

authors： Amichai E,Yovel Y

更新日期：2017-03-28 00:00:00