Toxic Injury to Muscle Tissue of Rats Following Acute Oximes Exposure.

abstract：:The origin and domestication of cultivated barley have long been under debate. A population-based resequencing and phylogenetic analysis of the single copy of RPB2 gene was used to address barley domestication, to explore genetic differentiation of barley populations on the worldwide scale, and to understand gene-pool...

journal_title：Scientific reports

authors： Wang Y,Ren X,Sun D,Sun G

更新日期：2016-10-27 00:00:00

abstract：:Clinical data have been equivocal and controversial as to the benefits to the brain and cognition of hormone therapy (HT) in postmenopausal women. Recent reevaluation of the role of estrogens proposed that HT may effectively prevent the deleterious effects of aging on cognition, and reduces the risks of dementia, incl...

journal_title：Scientific reports

authors： Girard R,Météreau E,Thomas J,Pugeat M,Qu C,Dreher JC

更新日期：2017-03-21 00:00:00

abstract：:Despite the development of crystal engineering, it remains a great challenge to predict the crystal structure even for the simplest molecules, and a clear link between molecular and crystal symmetry is missing in general. Here we demonstrate that the two-dimensional (2D) crystallization of heterocirculenes on a Au(111...

journal_title：Scientific reports

authors： Xiao WD,Zhang YY,Tao L,Aït-Mansour K,Chernichenko KY,Nenajdenko VG,Ruffieux P,Du SX,Gao HJ,Fasel R

更新日期：2014-06-24 00:00:00

abstract：:Temperature index (TI) models are convenient for modelling glacier ablation since they require only a few input variables and rely on simple empirical relations. The approach is generally assumed to be reliable at lower elevations (below 3500 m above sea level, a.s.l) where air temperature (Ta) relates well to the ene...

journal_title：Scientific reports

authors： Litt M,Shea J,Wagnon P,Steiner J,Koch I,Stigter E,Immerzeel W

更新日期：2019-03-27 00:00:00

abstract：:Amino acid biosynthesis pathways observed in nature typically require enzymes that are made with the amino acids they produce. For example, Escherichia coli produces cysteine from serine via two enzymes that contain cysteine: serine acetyltransferase (CysE) and O-acetylserine sulfhydrylase (CysK/CysM). To solve this c...

journal_title：Scientific reports

authors： Fujishima K,Wang KM,Palmer JA,Abe N,Nakahigashi K,Endy D,Rothschild LJ

更新日期：2018-01-29 00:00:00

abstract：:We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1-42), tTau and pTau CSF concentrat...

journal_title：Scientific reports

authors： Blennow K,Shaw LM,Stomrud E,Mattsson N,Toledo JB,Buck K,Wahl S,Eichenlaub U,Lifke V,Simon M,Trojanowski JQ,Hansson O

更新日期：2019-12-13 00:00:00

abstract：:Latent class modeling can be used to combine the results of multiple tests to compare the sensitivity and specificity of those tests in the absence of a gold standard. Seroepidemiology for chlamydia infection may be useful for determining the cumulative risk of infection within a population. Initial studies using the ...

journal_title：Scientific reports

authors： Wiegand RE,Cooley G,Goodhew B,Banniettis N,Kohlhoff S,Gwyn S,Martin DL

更新日期：2018-03-09 00:00:00

abstract：:Associations between HLA class I alleles and HIV progression in populations exhibiting Amerindian and Caucasian genetic admixture remain understudied. Using univariable and multivariable analyses we evaluated HLA associations with five HIV clinical parameters in 3,213 HIV clade B-infected, ART-naïve individuals from M...

journal_title：Scientific reports

authors： Valenzuela-Ponce H,Alva-Hernández S,Garrido-Rodríguez D,Soto-Nava M,García-Téllez T,Escamilla-Gómez T,García-Morales C,Quiroz-Morales VS,Tapia-Trejo D,Del Arenal-Sánchez S,Prado-Galbarro FJ,Hernández-Juan R,Rodríguez-Aguirre E,

更新日期：2018-04-17 00:00:00

abstract：:This work serves as a proof-of-concept for bacterially derived SimCells (Simple Cells), which contain the cell machinery from bacteria and designed DNA (or potentially a simplified genome) to instruct the cell to carry out novel, specific tasks. SimCells represent a reprogrammable chassis without a native chromosome, ...

journal_title：Scientific reports

authors： Rampley CPN,Davison PA,Qian P,Preston GM,Hunter CN,Thompson IP,Wu LJ,Huang WE

更新日期：2017-08-03 00:00:00

abstract：:We sequenced coding regions of the cluster of differentiation 36 (CD36) gene in 184 French individuals of European ancestry presenting simultaneously with type 2 diabetes (T2D), arterial hypertension, dyslipidemia, and coronary heart disease. We identified rare missense mutations (p.Pro191Leu/rs143150225 and p.Ala252V...

journal_title：Scientific reports

authors： Meyre D,Andress EJ,Sharma T,Snippe M,Asif H,Maharaj A,Vatin V,Gaget S,Besnard P,Choquet H,Froguel P,Linton KJ

更新日期：2019-11-20 00:00:00

abstract：:Ionizing radiation (IR)-induced intestinal damage is characterized by a loss of intestinal crypt cells, intestinal barrier disruption and translocation of intestinal microflora resulting in sepsis-mediated lethality. We have shown that mice lacking C/EBPδ display IR-induced intestinal and hematopoietic injury and leth...

journal_title：Scientific reports

authors： Banerjee S,Fu Q,Shah SK,Melnyk SB,Sterneck E,Hauer-Jensen M,Pawar SA

更新日期：2019-09-27 00:00:00

abstract：:Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the ...

journal_title：Scientific reports

authors： Nozari V,Calahoo C,Tuffnell JM,Adelhelm P,Wondraczek K,Dutton SE,Bennett TD,Wondraczek L

更新日期：2020-02-26 00:00:00

abstract：:Fowl cholera is a serious, highly contagious disease caused by the bacterium Pasteurella multocida (P. multocida) in a range of avian species and is characterized by an acute form of septicaemia. The pathogenic mechanism of chicken lung injury caused by the bacterium is unclear. Therefore, P. multocida Q (a reference ...

journal_title：Scientific reports

authors： Li W,Tang Q,Dai N,Feng W,Xie C,Cheng G,Liu X,Zhang W,Hu X,Gu C

更新日期：2020-04-14 00:00:00

abstract：:The prognostic factors of patients who undergo radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is not fully elucidated. We aimed to investigate the role of liver stiffness (LS) and spleen stiffness (SS) measured by acoustic radiation force impulse (ARFI) elastography in determining the prognoses of pa...

journal_title：Scientific reports

authors： Lee PC,Chiou YY,Chiu NC,Chen PH,Liu CA,Kao WY,Huo TI,Huang YH,Hou MC,Lin HC,Wu JC,Su CW

更新日期：2020-02-06 00:00:00

abstract：:At the basis of a trophic web, coprophagous animals like dung beetles (Scarabaeoidea) utilize resources that may have advantages (easy gain and handling) as well as drawbacks (formerly processed food). Several studies have characterized the nutrients, e.g. C/N ratios and organic matter content, for specific types of d...

journal_title：Scientific reports

authors： Frank K,Brückner A,Hilpert A,Heethoff M,Blüthgen N

更新日期：2017-09-22 00:00:00

abstract：:Ubiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction between cytochrome c1 and c. Recent genome-wide transcriptomic and epigenomic profiling of clear cell renal cell ...

journal_title：Scientific reports

authors： Luo Y,Medina Bengtsson L,Wang X,Huang T,Liu G,Murphy S,Wang C,Koren J 3rd,Schafer Z,Lu X

更新日期：2020-09-14 00:00:00

abstract：:The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model for Duchenne muscular dystrophy. Although disease progression in the mouse does not perfectly model the human disease, it shares many pathological features. Early characterizations of the model reported severe pathology through ear...

journal_title：Scientific reports

authors： Massopust RT,Lee YI,Pritchard AL,Nguyen VM,McCreedy DA,Thompson WJ

更新日期：2020-10-14 00:00:00

abstract：:Myosin X (Myo10), an actin-associated molecular motor, has a clear role in filopodia induction and cell migration in vitro, but its role in vivo in mammals is not well understood. Here, we investigate the role of Myo10 in melanocyte lineage and melanoma induction. We found that Myo10 knockout (Myo10KO) mice exhibit a ...

journal_title：Scientific reports

authors： Tokuo H,Bhawan J,Coluccio LM

更新日期：2018-07-11 00:00:00

abstract：:Mammalian Na+/Ca2+ exchangers, NCX1 and NCX3, generate splice variants, whereas NCX2 does not. The CBD1 and CBD2 domains form a regulatory tandem (CBD12), where Ca2+ binding to CBD1 activates and Ca2+ binding to CBD2 (bearing the splicing segment) alleviates the Na+-induced inactivation. Here, the NCX2-CBD12, NCX3-CBD...

journal_title：Scientific reports

authors： Giladi M,Lee SY,Ariely Y,Teldan Y,Granit R,Strulovich R,Haitin Y,Chung KY,Khananshvili D

更新日期：2017-04-20 00:00:00

abstract：:Spin-coated self-assemblies of colloidal particles have been developed recently as an attractive close-packed monolayer of the particles for a variety of applications, but they are limited by the small area of their monolayers, especially given their low uniformity and monolayer coverage on large-area substrates. We r...

journal_title：Scientific reports

authors： Park B,Na SY,Bae IG

更新日期：2019-08-07 00:00:00

abstract：:Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. The relation of bacterial factors and unfavorable outcomes remains controversial. We retrospectively reviewed clinical data of patients with bacteremia caused by MRSA with vancomycin MIC ...

journal_title：Scientific reports

authors： Yang CC,Sy CL,Huang YC,Shie SS,Shu JC,Hsieh PH,Hsiao CH,Chen CJ

更新日期：2018-05-18 00:00:00

abstract：:The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites ...

journal_title：Scientific reports

authors： Nor NSM,Yip CW,Ibrahim N,Jaafar MH,Rashid ZZ,Mustafa N,Hamid HHA,Chandru K,Latif MT,Saw PE,Lin CY,Alhasa KM,Hashim JH,Nadzir MSM

更新日期：2021-01-28 00:00:00

abstract：:The structure and function of cellular membranes were sustained by redox-enzymes. We studied the interaction between the oxidative stress caused by excessive accumulation of ZnO-nanoparticles (ZnO-NPs) in plants and the role of redox-enzymes that can alleviate this stress. The crude callus extract from pomegranate, wh...

journal_title：Scientific reports

authors： Farghaly FA,Radi AA,Al-Kahtany FA,Hamada AM

更新日期：2020-11-12 00:00:00

abstract：:The acronymously named "ESKAPE" pathogens represent a group of bacteria that continue to pose a serious threat to human health, not only due to their propensity for repeated emergence, but also due to their ability to "eskape" antibiotic treatment. The evolution of multi-drug resistance in these pathogens alone has gr...

journal_title：Scientific reports

authors： Hubick S,Jayaraman A,McKeen A,Reid S,Alcorn J,Stavrinides J,Sterenberg BT

更新日期：2017-02-06 00:00:00

abstract：:Temperature-modulated space-charge-limited-current spectroscopy (TMSCLC) is applied to quantitatively evaluate the density of trap states in the band-gap with high energy resolution of semiconducting hybrid lead halide perovskite single crystals. Interestingly multicomponent deep trap states were observed in the pure ...

journal_title：Scientific reports

authors： Pospisil J,Zmeskal O,Nespurek S,Krajcovic J,Weiter M,Kovalenko A

更新日期：2019-03-04 00:00:00

abstract：:We have quantitatively evaluated the macular and peripapillary microvascular changes in eyes with chiasmal compression caused by brain tumors compared with healthy control eyes using optical coherence tomography angiography (OCT-A) and correlated them with other ocular parameters. This cross-sectional study involved t...

journal_title：Scientific reports

authors： Lee GI,Park KA,Oh SY,Kong DS

更新日期：2020-02-07 00:00:00

abstract：:While molecular-targeted drugs have demonstrated strong therapeutic efficacy against diverse diseases such as cancer and infection, the appearance of drug resistance associated with genetic variations in individual patients or pathogens has severely limited their clinical efficacy. Therefore, precision medicine approa...

journal_title：Scientific reports

authors： Ono F,Chiba S,Isaka Y,Matsumoto S,Ma B,Katayama R,Araki M,Okuno Y

更新日期：2020-02-07 00:00:00

abstract：:A single-institution series using a (neo)adjuvant chemotherapy and interdigitated hyperfractionated split-course radiation therapy (CRT) treatment protocol for soft tissue sarcoma was reviewed. Our specific aims were to study recurrence rates and long-term toxicity. Between 1998 and 2016, 89 patients with non-metastat...

journal_title：Scientific reports

authors： Nevala R,Tukiainen E,Tarkkanen M,Böhling T,Blomqvist C,Sampo M

更新日期：2019-05-13 00:00:00

abstract：:Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-serine with low affini...

journal_title：Scientific reports

authors： Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS

更新日期：2017-04-07 00:00:00

abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...

journal_title：Scientific reports

authors： Tatematsu Y,Ogawa Y,Abe T,Kamoi M,Uchino M,Saijo-Ban Y,Yaguchi S,Mukai S,Mori T,Okamoto S,Tsubota K

更新日期：2014-10-22 00:00:00