Abstract:
:The structure and function of cellular membranes were sustained by redox-enzymes. We studied the interaction between the oxidative stress caused by excessive accumulation of ZnO-nanoparticles (ZnO-NPs) in plants and the role of redox-enzymes that can alleviate this stress. The crude callus extract from pomegranate, which was treated with 0, 10, and 150 µg mL-1 ZnO-NPs or bulk particles (ZnO-BPs), was applied to study the activity and kinetics of redox-enzymes. The elevated ZnO-NPs, enhanced the lipoxygenase and polyphenol oxidase activity, while the ZnO-BPs did not modify them. The activities of superoxide dismutase, catalase, and phenylalanine ammonia-lyase were induced under ZnO-NPs or BPs treatments, whilst the opposite trend of peroxidase was observed. Ascorbate peroxidase activity increased under ZnO-NPs treatments but decreased under ZnO-BPs. The kinetics activity of enzymes showed changes under different levels of NPs and BPs. Additionally, NPs or BPs treatments reduced the uptake of copper, iron, magnesium, but increased zinc accumulation in callus tissues. Meanwhile, these treatments enhanced the accumulation of manganese ions but did not affect the accumulation of potassium and phosphorous in ZnO-NPs or BPs-stressed calli. Collectively, these results gave a quantitative evaluation of the competition of zinc and other minerals on the carriers, and in addition, they provided a basis for how to control ZnO-NPs or BPs toxicity via redox-enzymes.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Farghaly FA,Radi AA,Al-Kahtany FA,Hamada AMdoi
10.1038/s41598-020-76664-4subject
Has Abstractpub_date
2020-11-12 00:00:00pages
19722issue
1issn
2045-2322pii
10.1038/s41598-020-76664-4journal_volume
10pub_type
杂志文章abstract::Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07024
更新日期:2014-11-12 00:00:00
abstract::Hirschsprung disease (HSCR) is a common cause of functional colonic obstruction in children. The currently available genetic testing is often inadequate as it mainly focuses on RET and several other genes, accounting for only 15-20% of cases. To identify novel, potentially pathogenic variants, we isolated a panel of g...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-017-14835-6
更新日期:2017-11-01 00:00:00
abstract::The effects of transcranial direct current stimulation (tDCS) on motor cortical excitability are highly variable between individuals. Inter-individual differences in the electric fields generated in the brain by tDCS might play a role in the variability. Here, we explored whether these fields are related to excitabili...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-018-37226-x
更新日期:2019-01-24 00:00:00
abstract::Plant evolutionary history influences the taxonomic composition of the root-associated bacterial community, but whether it can also modulate its functioning is unknown. Here, we tested the hypothesis that crop diversification is a significant factor determining the ecology of the functional group of nitrogen-fixing ba...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21690
更新日期:2016-02-23 00:00:00
abstract::Injection of pure spin current using a nonlocal geometry is a promising method for controlling magnetization in spintronic devices from the viewpoints of increasing freedom in device structure and avoiding problems related to charge current. Here, we report an experimental demonstration of magnetization switching of a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56082-x
更新日期:2019-12-20 00:00:00
abstract::In this study, we made a comparative efficacy and safety assessment of two different fixed combinations of drugs, viz., tafluprost/timolol (TAF/TIM) and latanoprost/carteolol (LAT/CAR), by determining their effects on intraocular pressure (IOP) in ocular normotensive monkeys and examining their toxic effects on ocular...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44028-2
更新日期:2019-05-16 00:00:00
abstract::Chloromethane (CH3Cl) is a toxic gas mainly produced naturally, in particular by plants, and its emissions contribute to ozone destruction in the stratosphere. Conversely, CH3Cl can be degraded and used as the sole carbon and energy source by specialised methylotrophic bacteria, isolated from a variety of environments...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17421-y
更新日期:2017-12-14 00:00:00
abstract::Congenital reproductive tract anomalies could impair fertility. Female and male reproductive tracts are developed from Müllerian ducts and Wolffian ducts, respectively, involving initiation, elongation and differentiation. Genetic basis solely for distal reproductive tract development is largely unknown. Lhfpl2 (lipom...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23037
更新日期:2016-03-11 00:00:00
abstract::The deregulation of autophagy is involved in liver regeneration. Here, we investigated the role of autophagy in the regulation of liver regeneration after partial hepatectomy (PHx) and the development of pharmacological interventions for improved liver regeneration after PHx. We show that autophagy was activated in th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15807
更新日期:2015-10-30 00:00:00
abstract::Sulfonylureas are commonly used to treat type 2 diabetes mellitus. Despite awareness of their effects on cardiac physiology, a knowledge gap exists regarding their effects on cardiovascular events in real-world populations. Prior studies reported sulfonylurea-associated cardiovascular death but not serious arrhythmoge...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66668-5
更新日期:2020-06-22 00:00:00
abstract::Ambient seismic noise is characterized by randomness incurred by the random position and strength of the noise sources as well as the heterogeneous properties of the medium through which it propagates. Here we use ambient noise data recorded prior to the 1996 Gjálp eruption in Iceland in order to show that a reduction...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37733
更新日期:2016-11-24 00:00:00
abstract::Activated sludge granules and flocs have their inherent advantages and disadvantages for wastewater treatment due to their different characteristics. So far quantitative information on their evaluation is still lacking. This work provides a quantitative and comparative evaluation on the characteristics and pollutant r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42910
更新日期:2017-02-17 00:00:00
abstract::The microtubule cytoskeleton is composed of α-tubulin and β-tubulin heterodimers, and it serves to regulate the shape, motility, and division of a cell. Post-translational modifications including acetylation are closely associated with the functional aspects of the microtubule, involving in a number of pathological di...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27775
更新日期:2016-06-08 00:00:00
abstract::Neurotransmission and secretion of hormones involve a sequence of protein/lipid interactions with lipid turnover impacting on vesicle trafficking and ultimately fusion of secretory vesicles with the plasma membrane. We previously demonstrated that sphingosine, a sphingolipid metabolite, promotes formation of the SNARE...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05948-z
更新日期:2017-07-20 00:00:00
abstract::The adipogenic process is characterized by the expression of adipocyte differentiation markers that lead to changes in cell metabolism and to the accumulation of lipid droplets. Moreover, during early adipogenesis, cells undergo a strong downregulation of translational activity with a decrease in cell size, proliferat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42005-3
更新日期:2019-04-04 00:00:00
abstract::Known γ-secretase inhibitors or modulators display an undesirable pharmacokinetic profile and toxicity and have therefore not been successful in clinical trials for Alzheimer's disease (AD). So far, no compounds from natural products have been identified as direct inhibitors of γ-secretase. To search for bioactive mol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16541
更新日期:2015-11-16 00:00:00
abstract::Intensive research has been focused on the synthesis of long-lasting SrAl2O4:EuDy in luminescent materials field. Traditionally, SrAl2O4:EuDy is synthesized in bulk form by solid state. However, their development remains restrained due to this technique is not compatible with large-scale production, sustainability and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00541-w
更新日期:2017-03-28 00:00:00
abstract::Memory function deficits induced by Alzheimer's disease (AD) are believed to be one of the causes of an increased risk of tripping in patients. Working memory contributes to accurate stepping over obstacles during locomotion, and AD-induced deficits of this memory function may lead to an increased risk of contact with...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07220
更新日期:2014-11-27 00:00:00
abstract::Leukocyte-platelet rich fibrin (L-PRF) is extensively used in the dentistry field and other clinical scenarios due to its regeneration properties. The goal of the present study was to depict the L-PRF secretome and how it changes over time. We obtained L-PRF membranes and cultured them in DMEM. The secretome was colle...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71419-7
更新日期:2020-09-03 00:00:00
abstract::Unnatural chiral α-amino acids are widely used in fields of organic chemistry, biochemistry and medicinal chemistry, and their synthesis has attracted extensive attention. Although the asymmetric synthesis provides some efficient protocols, noble and elaborate catalysts, ligands and additives are usually required whic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26161
更新日期:2016-05-17 00:00:00
abstract::Time-encoding MRI is a single-scan method that uses traditional k-encoding only in one direction. In the orthogonal "time-encoding" direction, a string of echoes appears in an order that depends on the position of the corresponding spin packets. In one variant of time-encoding, this is achieved by using a series of se...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28460-4
更新日期:2018-07-18 00:00:00
abstract::The effect of substrate surface roughening on the capacitance of Ni(OH)2/NiOOH nanowall array samples produced via chemical bath deposition for 2, 4, 6, 24 and 48 h on an as-received stainless steel substrate and the same substrate after sandblasting has been investigated. Symmetric cells were subjected to 120,000 cha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53365-1
更新日期:2019-11-14 00:00:00
abstract::Recent advances in microfluidic cell cultures enable the construction of in vitro human skin models that can be used for drug toxicity testing, disease study. However, current in vitro skin model have limitations to emulate real human skin due to the simplicity of model. In this paper, we describe the development of '...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37471
更新日期:2016-11-21 00:00:00
abstract::Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract of uncertain origin, which includes ulcerative colitis (UC) and Crohn's disease (CD). The composition of gut microbiota may change in IBD affected individuals, but whether dysbiosis is the cause or the consequence of infla...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10034-5
更新日期:2017-08-25 00:00:00
abstract::Facio-Scapulo Humeral dystrophy (FSHD) is the third most common myopathy, affecting 1 amongst 10,000 individuals (FSHD1, OMIM #158900). This autosomal dominant pathology is associated in 95% of cases with genetic and epigenetic alterations in the subtelomeric region at the extremity of the long arm of chromosome 4 (q ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46861-x
更新日期:2019-07-17 00:00:00
abstract::Polymer-supported nanozero-valent iron composites (D001-nZVI) were fabricated for the removal of lead ions from aqueous solutions by embedding nZVI into the porous polystyrene anion exchanger D001. Humic acid (HA) was selected as a model species because of its ubiquitous existence to gain insight into the influencing ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76362-1
更新日期:2020-11-12 00:00:00
abstract::Microinjection is commonly performed to achieve fish transgenesis; however, due to difficulties associated with this technique, new strategies are being developed. Here we evaluate the potential of lentiviral particles to genetically modify Nile tilapia cells to achieve transgenesis using three different approaches: s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44317
更新日期:2017-03-20 00:00:00
abstract::Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the anterograde axonal transport of Golgi-derived vesicles and the concomitant exocytosis of these vesicles at the growth cone. However, the functions of Rab33 in vivo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38468-5
更新日期:2019-02-12 00:00:00
abstract::High temperature stable selective emitters can significantly increase efficiency and radiative power in thermophotovoltaic (TPV) systems. However, optical properties of structured emitters reported so far degrade at temperatures approaching 1200 °C due to various degradation mechanisms. We have realized a 1D structure...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43640-6
更新日期:2019-05-10 00:00:00
abstract::We measured the magnitude of submarine fresh groundwater discharge (SFGD) and associated nutrient inputs to Jocheon harbor, on Jeju Island, Korea, during four sampling periods, in order to determine the link between SFGD and Ulva sp. green tide development. Good correlations among salinity, 222Rn, and dissolved inorga...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06711-0
更新日期:2017-07-24 00:00:00