Novel HLA class I associations with HIV-1 control in a unique genetically admixed population.

abstract：:The current assessment of corneal vascularisation (CV) relies on slit-lamp examination, which may be subjective. Dye-based angiographies, like indocyanine green angiography (ICGA), allows for good visualisation of anterior segment blood vessels. However, ICGA is invasive and can be associated with systemic adverse eff...

journal_title：Scientific reports

authors： Ong HS,Tey KY,Ke M,Tan B,Chua J,Schmetterer L,Mehta JS,Ang M

更新日期：2021-01-13 00:00:00

abstract：:Adulterant herbal materials are a threat to consumer safety. In this study, we used DNA barcoding to investigate the proportions and varieties of adulterant species in traditional Chinese medicine (TCM) markets. We used a DNA barcode database of TCM (TCMD) that was established by our group to investigate 1436 samples ...

journal_title：Scientific reports

authors： Han J,Pang X,Liao B,Yao H,Song J,Chen S

更新日期：2016-01-07 00:00:00

abstract：:Revisiting threat-related scenes elicits fear and activates a brain network related to cognitive-affective processing. Prior experience may contribute to the present fearful experience. We aimed to investigate (a) patterns of brain activation associated with individual differences in past fearful experiences (pFear) a...

journal_title：Scientific reports

authors： Lin CS,Wu CY,Wu SY,Lin HH

更新日期：2018-03-23 00:00:00

abstract：:Cinnabar is a natural mercury sulfide (HgS) mineral of volcanic or hydrothermal origin that is found worldwide. It has been mined prehistorically and historically in China, Japan, Europe, and the Americas to extract metallic mercury (Hg(0)) for use in metallurgy, as a medicinal, a preservative, and as a red pigment fo...

journal_title：Scientific reports

authors： Emslie SD,Brasso R,Patterson WP,Carlos Valera A,McKenzie A,Maria Silva A,Gleason JD,Blum JD

更新日期：2015-10-01 00:00:00

abstract：:The typical photodetectors can only detect one specific optical spectral band, such as InGaAs and graphene-PbS quantum dots for near-infrared (NIR) light detection, CdS and Si for visible light detection, and ZnO and III-nitrides for UV light detection. So far, none of the developed photodetector can achieve the multi...

journal_title：Scientific reports

authors： Sang L,Hu J,Zou R,Koide Y,Liao M

更新日期：2013-01-01 00:00:00

abstract：:An intermediate band in the band gap of semiconductors is fundamental to the development of the intermediate band solar cells, but it is usually produced artificially, which imposes technical challenges on the experimental realization. Here we found that there are natural intermediate bands in the band gaps of the I2-...

journal_title：Scientific reports

authors： Liu Q,Cai Z,Han D,Chen S

更新日期：2018-01-25 00:00:00

abstract：:Interferon (IFN)-γ release assays (IGRAs) are used to diagnose latent tuberculosis (TB) infection (LTBI). To improve the accuracy of these tests, different approaches, such as alternative cytokine detection and using different antigens, are considered. Following this purpose, this study aims to evaluate the addition o...

journal_title：Scientific reports

authors： Villar-Hernández R,Blauenfeldt T,García-García E,Muriel-Moreno B,De Souza-Galvão ML,Millet JP,Sabriá F,Sánchez-Montalvá A,Ruiz-Manzano J,Pilarte J,Jiménez MA,Centeno C,Martos C,Molina-Pinargote I,González-Díaz YD,Santiago J

更新日期：2020-08-06 00:00:00

abstract：:We study the rotational dynamics of solid chiral and birefringent microparticles induced by elliptically polarized laser light in optical tweezers. We find that both reflection of left circularly polarized light and residual linear retardance affect the particle dynamics. The degree of ellipticity of laser light neede...

journal_title：Scientific reports

authors： Donato MG,Mazzulla A,Pagliusi P,Magazzù A,Hernandez RJ,Provenzano C,Gucciardi PG,Maragò OM,Cipparrone G

更新日期：2016-09-07 00:00:00

abstract：:High altitude pulmonary edema (HAPE) susceptibility is associated with EGLN1 polymorphisms, we hypothesized that HAPE-susceptible (HAPE-S, had HAPE episode in past) subjects may exhibit abnormal HIF1α levels in normoxic conditions. We measured HIF1α levels in HAPE-S and HAPE resistant (HAPE-R, no HAPE episode) individ...

journal_title：Scientific reports

authors： Soree P,Gupta RK,Singh K,Desiraju K,Agrawal A,Vats P,Bharadwaj A,Baburaj TP,Chaudhary P,Singh VK,Verma S,Bajaj AC,Singh SB

更新日期：2016-05-23 00:00:00

abstract：:Detecting and analysing motion is a key feature of Smart Homes and the connected sensor vision they embrace. At present, most motion sensors operate in line-of-sight Doppler shift schemes. Here, we propose an alternative approach suitable for indoor environments, which effectively constitute disordered cavities for ra...

journal_title：Scientific reports

authors： Del Hougne P,F Imani M,Sleasman T,Gollub JN,Fink M,Lerosey G,Smith DR

更新日期：2018-04-25 00:00:00

abstract：:The aim of this study was to use functional neuroimaging to investigate whether oxytocin modulates the neural response to visual food cues in brain regions involved in the control of food intake. Twenty-four normal weight volunteers received intranasal oxytocin (24 IU) or placebo in a double-blind, randomized crossove...

journal_title：Scientific reports

authors： van der Klaauw AA,Ziauddeen H,Keogh JM,Henning E,Dachi S,Fletcher PC,Farooqi IS

更新日期：2017-06-27 00:00:00

abstract：:We advance the concept that the charge factors of the simple overlap model and the polarizabilities of Judd-Ofelt theory for the luminescence of europium complexes can be effectively and uniquely modeled by perturbation theory on the semiempirical electronic wave function of the complex. With only three adjustable con...

journal_title：Scientific reports

authors： Dutra JD,Lima NB,Freire RO,Simas AM

更新日期：2015-09-02 00:00:00

abstract：:Spontaneous ultra-weak photon emission from living organisms, designated as biophoton emission, is a generally observed phenomenon irrespective of the organism species. Biophoton emission is attributed to the production of excited molecules in a metabolic biochemical reaction, especially in processes involving reactiv...

journal_title：Scientific reports

authors： Usui S,Tada M,Kobayashi M

更新日期：2019-06-12 00:00:00

abstract：:Targeting epigenetic reader proteins by small molecule inhibitors represents a new therapeutic concept in autoimmune diseases such as rheumatoid arthritis (RA). Although inhibitors targeting bromodomain protein 1 (BRD1) are in development, the function of BRD1 has hardly been studied. We investigated the therapeutic p...

journal_title：Scientific reports

authors： Klein K,Kato M,Frank-Bertoncelj M,Kolling C,Ciurea A,Gay S,Ospelt C

更新日期：2018-07-24 00:00:00

abstract：:The thermal field theory is applied to fermionic superfluids by doubling the degrees of freedom of the BCS theory. We construct the two-mode states and the corresponding Bogoliubov transformation to obtain the BCS thermal vacuum. The expectation values with respect to the BCS thermal vacuum produce the statistical ave...

journal_title：Scientific reports

authors： Hou XY,Huang Z,Guo H,He Y,Chien CC

更新日期：2018-08-10 00:00:00

abstract：:Mammalian innate and acquired immune responses involve a coordinated, sequential, and self limiting sequence of events controlled by positive and negative regulatory mechanism. MicroRNAs have been implicated as a negative regulator for diverse biological events including immune responses. However, the involvement of m...

journal_title：Scientific reports

authors： Jun H,Ying H,Daiwen C,Bing Y,Xiangbing M,Ping Z,Jie Y,Zhiqing H,Junqiu L

更新日期：2015-07-31 00:00:00

abstract：:Psoriasis is a chronic, relapsing inflammatory skin disease. The pathogenesis of psoriasis is complex and has not been fully understood. C10orf99 was a recently identified human antimicrobial peptide whose mRNA expression is elevated in psoriatic human skin samples. In this study, we investigated the functional roles ...

journal_title：Scientific reports

authors： Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y

更新日期：2018-06-05 00:00:00

abstract：:The innovation of iconic gestures is essential to establishing the vocabularies of signed languages, but might iconicity also play a role in the origin of spoken words? Can people create novel vocalizations that are comprehensible to naïve listeners without prior convention? We launched a contest in which participants...

journal_title：Scientific reports

authors： Perlman M,Lupyan G

更新日期：2018-02-08 00:00:00

abstract：:Phytophthora blight is one of the most serious diseases affecting melon (Cucumis melo) production. Due to the lack of highly resistant germplasms, the progress on disease-resistant research is slow. To understand the genetics of melon resistance to Phytophthora capsici, an F2 population containing 498 individuals was ...

journal_title：Scientific reports

authors： Wang P,Xu X,Zhao G,He Y,Hou C,Kong W,Zhang J,Liu S,Xu Y,Xu Z

更新日期：2020-11-24 00:00:00

abstract：:Ca2+ release-activated Ca2+ (CRAC) channels elevate cytoplasmic Ca2+ concentration, which is essential for T cell activation, differentiation and effector functions. T cell receptor stimulation induces depletion of the endoplasmic reticulum (ER) Ca2+ stores, which is sensed by stromal interaction molecule 1 (STIM1). S...

journal_title：Scientific reports

authors： Woo JS,Sun Z,Srikanth S,Gwack Y

更新日期：2020-09-02 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:Resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has become the main clinical challenge of advanced lung cancer. This research aimed to explore the role of PARP1-mediated autophagy in the progression of TKI therapy. PARP1-mediated autophagy was evaluated in vitro by CCK-8 assay, cl...

journal_title：Scientific reports

authors： Zhang Z,Lian X,Xie W,Quan J,Liao M,Wu Y,Yang ZZ,Wang G

更新日期：2020-12-01 00:00:00

abstract：:Viral hepatitis leads to immune-mediated liver injury. The rate of disease progression varies between individuals. We aimed to phenotype immune cells associated with preservation of normal liver function during hepatitis C virus (HCV) infection. Clinical data and specimens were obtained from 19 HCV-infected patients u...

journal_title：Scientific reports

authors： Doyle EH,Aloman C,El-Shamy A,Eng F,Rahman A,Klepper AL,Haydel B,Florman SS,Fiel MI,Schiano T,Branch AD

更新日期：2021-01-15 00:00:00

abstract：:Leucine-rich repeat kinase 2 (LRRK2) is a promising therapeutic target for the treatment of Parkinson's disease (PD) and LRRK2 kinase inhibitors are currently being tested in early phase clinical trials. In order to ensure the highest chance of success, a biomarker-guided entry into clinical trials is key. LRRK2 phosp...

journal_title：Scientific reports

authors： Gonzalez-Hunt CP,Thacker EA,Toste CM,Boularand S,Deprets S,Dubois L,Sanders LH

更新日期：2020-10-14 00:00:00

abstract：:ZnO, aside from TiO2, has been considered as a promising material for purification and disinfection of water and air, and remediation of hazardous waste, owing to its high activity, environment-friendly feature and lower cost. However, their poor visible light utilization greatly limited their practical applications. ...

journal_title：Scientific reports

authors： Zhang X,Qin J,Xue Y,Yu P,Zhang B,Wang L,Liu R

更新日期：2014-04-04 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Caldwell DJ,Cronin JA,Wu J,Weaver KE,Ko AL,Rao RPN,Ojemann JG

更新日期：2019-12-27 00:00:00

abstract：:Diabetes mellitus accelerates vascular calcification (VC) and increases the risk of end-stage renal disease (ESRD). Nevertheless, the impact of VC in renal disease progression in type 2 diabetes mellitus (T2DM) is poorly understood. We addressed the effect of VC and mechanisms involved in renal dysfunction in a murine...

journal_title：Scientific reports

authors： Almeida YE,Fessel MR,do Carmo LS,Jorgetti V,Farias-Silva E,Pescatore LA,Gamarra LF,Andrade MC,Simplicio-Filho A,Mangueira CLP,Rangel ÉB,Liberman M

更新日期：2020-01-09 00:00:00

abstract：:Ocean warming increasingly endangers the fitness of marine invertebrates. Transgenerational effects (TE) potentially mitigate the impacts of environmental stress on the embryos of marine invertebrates. The molecular mechanisms, however, remain largely unknown. Using high-throughput RNA sequencing technology, we invest...

journal_title：Scientific reports

authors： Shi D,Zhao C,Chen Y,Ding J,Zhang L,Chang Y

更新日期：2020-05-13 00:00:00

abstract：:The focus of this study is to evaluate the efficacy of Machine Learning (ML) algorithms in the long-lead prediction of El Niño (La Niña) Modoki (ENSO Modoki) index (EMI). We evaluated two widely used non-linear ML algorithms namely Support Vector Regression (SVR) and Random Forest (RF) to forecast the EMI at various l...

journal_title：Scientific reports

authors： Pal M,Maity R,Ratnam JV,Nonaka M,Behera SK

更新日期：2020-01-15 00:00:00

abstract：:As part of efforts to reduce pressure on the Amazon and other biomes, one approach considered by Brazilian authorities and scientists is more intensive use of the soils of the interior of the northeast of the country, which are generally sandy, with low contents of organic matter and low water holding capacity and are...

journal_title：Scientific reports

authors： Batista EMCC,Shultz J,Matos TTS,Fornari MR,Ferreira TM,Szpoganicz B,de Freitas RA,Mangrich AS

更新日期：2018-07-16 00:00:00