Genetic mapping and candidate gene analysis for melon resistance to Phytophthora capsici.

Abstract:

:Phytophthora blight is one of the most serious diseases affecting melon (Cucumis melo) production. Due to the lack of highly resistant germplasms, the progress on disease-resistant research is slow. To understand the genetics of melon resistance to Phytophthora capsici, an F2 population containing 498 individuals was developed by crossing susceptible line E31 to highly resistant line ZQK9. Genetic analysis indicated that the resistance in ZQK9 was controlled by a dominant gene, tentatively named MePhyto. Through bulked-segregant analysis (BSA-Seq) and chromosome walking techniques, the MePhyto gene was mapped to a 52.44 kb interval on chromosome 12. In this region, there were eight genes and their expression patterns were validated by qRT-PCR. Among them, one wall-associated receptor kinase (WAK) gene MELO3C002430 was significantly induced in ZQK9 after P. capsici inoculation, but not in E31. Based on the non-synonymous mutation site in MELO3C002430, a cleaved amplified polymorphic sequence (CAPS) marker, CAPS2430, was developed and this maker was co-segregated with MePhyto in both F2 population and a collection of 36 melon accessions. Thus MELO3C002430 was considered as the candidate gene and CAPS2430 was a promising marker for marker-assisted selection (MAS) in breeding. These results lay a foundation for revealing the resistance mechanism of melon to P. capsici.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Wang P,Xu X,Zhao G,He Y,Hou C,Kong W,Zhang J,Liu S,Xu Y,Xu Z

doi

10.1038/s41598-020-77600-2

subject

Has Abstract

pub_date

2020-11-24 00:00:00

pages

20456

issue

1

issn

2045-2322

pii

10.1038/s41598-020-77600-2

journal_volume

10

pub_type

杂志文章
  • Syntactic and non-syntactic sources of interference by music on language processing.

    abstract::Music and language are complex hierarchical systems in which individual elements are systematically combined to form larger, syntactic structures. Suggestions that music and language share syntactic processing resources have relied on evidence that syntactic violations in music interfere with syntactic processing in l...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36076-x

    authors: Fiveash A,McArthur G,Thompson WF

    更新日期:2018-12-17 00:00:00

  • Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors.

    abstract::Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles; earlier during oncogenesis it suppresses neoplastic transformation an...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48420-w

    authors: Ear J,Dunkel Y,Mittal Y,Lim BBC,Liu L,Holda MK,Nitsche U,Barbazán J,Goel A,Janssen KP,Aznar N,Ghosh P

    更新日期:2019-08-20 00:00:00

  • Computational modeling of human reasoning processes for interpretable visual knowledge: a case study with radiographers.

    abstract::Visual reasoning is critical in many complex visual tasks in medicine such as radiology or pathology. It is challenging to explicitly explain reasoning processes due to the dynamic nature of real-time human cognition. A deeper understanding of such reasoning processes is necessary for improving diagnostic accuracy and...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77550-9

    authors: Li Y,Cao H,Allen CM,Wang X,Erdelez S,Shyu CR

    更新日期:2020-12-10 00:00:00

  • In Silico Models of DNA Damage and Repair in Proton Treatment Planning: A Proof of Concept.

    abstract::There is strong in vitro cell survival evidence that the relative biological effectiveness (RBE) of protons is variable, with dependence on factors such as linear energy transfer (LET) and dose. This is coupled with the growing in vivo evidence, from post-treatment image change analysis, of a variable RBE. Despite thi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56258-5

    authors: Smith EAK,Henthorn NT,Warmenhoven JW,Ingram SP,Aitkenhead AH,Richardson JC,Sitch P,Chadwick AL,Underwood TSA,Merchant MJ,Burnet NG,Kirkby NF,Kirkby KJ,Mackay RI

    更新日期:2019-12-27 00:00:00

  • Author Correction: Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-73944-x

    authors: Eger M,Bader M,Bree D,Hadar R,Nemirovski A,Tam J,Levy D,Pick CG,Gabet Y

    更新日期:2020-10-09 00:00:00

  • Influence of tunnel ionization to third-harmonic generation of infrared femtosecond laser pulses in air.

    abstract::Here we present an experimental as well as theoretical study of third-harmonic generation in tightly focused femtosecond filaments in air at the wavelength of [Formula: see text]. At low intensities, longitudinal phase matching is dominating in the formation of 3rd harmonics, whereas at higher intensities locked X-wav...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-74263-x

    authors: Tamulienė V,Juškevičiūtė G,Buožius D,Vaičaitis V,Babushkin I,Morgner U

    更新日期:2020-10-15 00:00:00

  • ENSO elicits opposing responses of semi-arid vegetation between Hemispheres.

    abstract::Semi-arid ecosystems are key contributors to the global carbon cycle and may even dominate the inter-annual variability (IAV) and trends of the land carbon sink, driven largely by the El Niño-Southern Oscillation (ENSO). The linkages between dynamics of semi-arid ecosystems and climate at the hemispheric scale however...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42281

    authors: Zhang A,Jia G,Epstein HE,Xia J

    更新日期:2017-02-09 00:00:00

  • Controlling striatal function via anterior frontal cortex stimulation.

    abstract::Motivational, cognitive and action goals are processed by distinct, topographically organized, corticostriatal circuits. We aimed to test whether processing in the striatum is under causal control by cortical regions in the human brain by investigating the effects of offline transcranial magnetic stimulation (TMS) ove...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21346-5

    authors: van Holstein M,Froböse MI,O'Shea J,Aarts E,Cools R

    更新日期:2018-02-19 00:00:00

  • In vitro Studies on The Inhibition of Replication of Zika and Chikungunya Viruses by Dolastane Isolated from Seaweed Canistrocarpus cervicornis.

    abstract::The lack of vaccines and antiviral treatment, along with the increasing number of cases of Zika virus (ZIKV) and Chikungunya virus (CHIKV) infections, emphasize the need for searching for new therapeutic strategies. In this context, the marine brown seaweed Canistrocarpus cervicornis has been proved to hold great anti...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65357-7

    authors: Cirne-Santos CC,de Souza Barros C,de Oliveira MC,Rabelo VW,Azevedo RC,Teixeira VL,Ferreira DF,de Palmer Paixão ICN

    更新日期:2020-05-19 00:00:00

  • Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver.

    abstract::Long non-coding RNAs (lncRNAs) regulate expression of protein-coding genes in cis through chromatin modifications including DNA methylation. Here we interrogated whether lncRNA genes may regulate transcription and methylation of their flanking or overlapping protein-coding genes in livers of mice exposed to a 12-week ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29993-4

    authors: Silva JP,van Booven D

    更新日期:2018-08-01 00:00:00

  • Genome-wide landscape of DNA methylomes and their relationship with mRNA and miRNA transcriptomes in oxidative and glycolytic skeletal muscles.

    abstract::The physiological, biochemical and functional differences between oxidative and glycolytic muscles play important roles in human metabolic health and in animal meat quality. To explore these differences, we determined the genome-wide landscape of DNA methylomes and their relationship with the mRNA and miRNA transcript...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep32186

    authors: Shen L,Du J,Xia Y,Tan Z,Fu Y,Yang Q,Li X,Tang G,Jiang Y,Wang J,Li M,Zhang S,Zhu L

    更新日期:2016-08-26 00:00:00

  • Fabrication of thickness controllable free-standing sandwich-structured hybrid carbon film for high-rate and high-power supercapacitor.

    abstract::Hybrid carbon films composed of graphene film and porous carbon film may give full play to the advantages of both carbon materials, and have great potential for application in energy storage and conversion devices. Unfortunately, there are very few reports on fabrication of hybrid carbon films. Here we demonstrate a s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07050

    authors: Wei H,Wei S,Tian W,Zhu D,Liu Y,Yuan L,Li X

    更新日期:2014-11-14 00:00:00

  • Systematic assessment of prescribed medications and short-term risk of myocardial infarction - a pharmacopeia-wide association study from Norway and Sweden.

    abstract::Wholesale, unbiased assessment of Scandinavian electronic health-care databases offer a unique opportunity to reveal potentially important undiscovered drug side effects. We examined the short-term risk of acute myocardial infarction (AMI) associated with drugs prescribed in Norway or Sweden. We identified 24,584 and ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44641-1

    authors: Sen A,Vardaxis I,Lindqvist BH,Brumpton BM,Strand LB,Bakken IJ,Vatten LJ,Romundstad PR,Ljung R,Mukamal KJ,Janszky I

    更新日期:2019-06-04 00:00:00

  • Effect of different types of olive oil pomace dietary supplementation on the rumen microbial community profile in Comisana ewes.

    abstract::Olive oil pomace (OOP) is a bio-waste rich in highly soluble polyphenols. OOP has been proposed as an additive in ruminant feeding to modulate rumen fermentations. Three groups of ewes were fed the following different diets: a control diet and two diets supplemented with OOP, obtained with a two-phase (OOP2) or three-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26713-w

    authors: Mannelli F,Cappucci A,Pini F,Pastorelli R,Decorosi F,Giovannetti L,Mele M,Minieri S,Conte G,Pauselli M,Rapaccini S,Viti C,Buccioni A

    更新日期:2018-05-31 00:00:00

  • Flexible thermoelectric films formed using integrated nanocomposites with single-wall carbon nanotubes and Bi2Te3 nanoplates via solvothermal synthesis.

    abstract::Single-wall carbon nanotubes (SWCNTs) and Bi2Te3 nanoplates are very promising thermoelectric materials for energy harvesting. When these two materials are combined, the resulting nanocomposites exhibit high thermoelectric performance and excellent flexibility. However, simple mixing of these materials is not effectiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73808-4

    authors: Yabuki H,Yonezawa S,Eguchi R,Takashiri M

    更新日期:2020-10-12 00:00:00

  • The Anopheles coluzzii microbiome and its interaction with the intracellular parasite Wolbachia.

    abstract::Wolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway using Aedes aegypti mosquitoes trans-infected with a non-natural Wolbachia strain to reduce dengue virus transmission. Less is known about the imp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-70745-0

    authors: Straub TJ,Shaw WR,Marcenac P,Sawadogo SP,Dabiré RK,Diabaté A,Catteruccia F,Neafsey DE

    更新日期:2020-08-14 00:00:00

  • High Throughput Experimentation Using DESI-MS to Guide Continuous-Flow Synthesis.

    abstract::We demonstrate the use of accelerated reactions with desorption electrospray ionization mass spectrometry (DESI-MS) as a tool for predicting the outcome of microfluidic reactions. DESI-MS was employed as a high throughput experimentation tool to provide qualitative predictions of reaction outcomes, so that vast region...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50638-7

    authors: Loren BP,Ewan HS,Avramova L,Ferreira CR,Sobreira TJP,Yammine K,Liao H,Cooks RG,Thompson DH

    更新日期:2019-10-14 00:00:00

  • Generation of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.

    abstract::CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04967-0

    authors: Oyama R,Takahashi M,Yoshida A,Sakumoto M,Takai Y,Kito F,Shiozawa K,Qiao Z,Arai Y,Shibata T,Araki Y,Endo M,Kawai A,Kondo T

    更新日期:2017-07-05 00:00:00

  • Water and Blood Repellent Flexible Tubes.

    abstract::A top-down scalable method to produce flexible water and blood repellent tubes is introduced. The method is based on replication of overhanging nanostructures from an aluminum tube template to polydimethylsiloxane (PDMS) via atomic layer deposition (ALD) assisted sacrificial etching. The nanostructured PDMS/titania tu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16369-3

    authors: Hoshian S,Kankuri E,Ras RHA,Franssila S,Jokinen V

    更新日期:2017-11-22 00:00:00

  • Refinement-cut: user-guided segmentation algorithm for translational science.

    abstract::In this contribution, a semi-automatic segmentation algorithm for (medical) image analysis is presented. More precise, the approach belongs to the category of interactive contouring algorithms, which provide real-time feedback of the segmentation result. However, even with interactive real-time contouring approaches t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05164

    authors: Egger J

    更新日期:2014-06-04 00:00:00

  • Traditional versus blended CPR training program: A randomized controlled non-inferiority study.

    abstract::Cardiopulmonary resuscitation (CPR) training and its quality are critical in improving the survival rate of cardiac arrest. This randomized controlled study investigated the efficacy of a newly developed CPR training program for the public in a Taiwanese setting. A total of 832 adults were randomized to either a tradi...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-020-67193-1

    authors: Chien CY,Fang SY,Tsai LH,Tsai SL,Chen CB,Seak CJ,Weng YM,Lin CC,Chien WC,Huang CH,Lin CY,Chaou CH,Liu PH,Tseng HJ,Chen JC,Peng SY,Cheng TH,Hsu KH,Ng CJ

    更新日期:2020-06-22 00:00:00

  • A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors.

    abstract::The most downstream elements of the Hippo pathway, the TEAD transcription factors, are regulated by several cofactors, such as Vg/VGLL1-3. Earlier findings on human VGLL1 and here on human VGLL3 show that these proteins interact with TEAD via a conserved amino acid motif called the TONDU domain. Surprisingly, our stud...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-74584-x

    authors: Mesrouze Y,Aguilar G,Bokhovchuk F,Martin T,Delaunay C,Villard F,Meyerhofer M,Zimmermann C,Fontana P,Wille R,Vorherr T,Erdmann D,Furet P,Scheufler C,Schmelzle T,Affolter M,Chène P

    更新日期:2020-10-15 00:00:00

  • Publisher Correction: Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene-gene interactions.

    abstract::A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41598-017-16210-x

    authors: Yang CH,Chuang LY,Lin YD

    更新日期:2017-11-23 00:00:00

  • Novel non-periodic spoof surface plasmon polaritons with H-shaped cells and its application to high selectivity wideband bandpass filter.

    abstract::In this paper, one kind of novel non-periodic spoof surface plasmon polaritons (SSPPs) with H-shaped cells is proposed. As we all know, the cutoff frequency exists inherently for the conventional comb-shaped SSPPs, which is a kind of periodic groove shape structures and fed by a conventional coplanar waveguide (CPW). ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20533-8

    authors: Gao X,Che W,Feng W

    更新日期:2018-02-06 00:00:00

  • HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver.

    abstract::Adaptive responses to hypoxia regulate hepatic lipid metabolism, but their consequences in nonalcoholic fatty liver disease (NAFLD) are largely unknown. Here, we show that hypoxia inducible factor-1 (HIF-1), a key determinant of hypoxic adaptations, prevents excessive hepatic lipid accumulation in the progression of N...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32586-w

    authors: Arai T,Tanaka M,Goda N

    更新日期:2018-09-21 00:00:00

  • Age and sex subgroups vulnerable to copycat suicide: evaluation of nationwide data in South Korea.

    abstract::Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53833-8

    authors: Yi H,Hwang J,Bae HJ,Kim N

    更新日期:2019-11-21 00:00:00

  • Essential role of the Na+-Ca2+ exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation.

    abstract::Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial energy balance as subst...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13478-x

    authors: Maiolino M,Castaldo P,Lariccia V,Piccirillo S,Amoroso S,Magi S

    更新日期:2017-10-12 00:00:00

  • Metabolomic Response of Skeletal Muscle to Aerobic Exercise Training in Insulin Resistant Type 1 Diabetic Rats.

    abstract::The etiology of insulin resistance in Type 1 Diabetes (T1D) is unknown, however it affects approximately 20% of T1D patients. Intramyocellular lipids (IMCL) have been identified as a mechanism of insulin resistance. We examined skeletal muscle of T1D rats to determine if alterations in lipid metabolism were evident an...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26379

    authors: Dotzert MS,Murray MR,McDonald MW,Olver TD,Velenosi TJ,Hennop A,Noble EG,Urquhart BL,Melling CW

    更新日期:2016-05-20 00:00:00

  • High throughput data analyses of the immune characteristics of Microtus fortis infected with Schistosoma japonicum.

    abstract::Microtus fortis exhibits natural resistance against Schistosoma japonicum, and the parasite cannot grow and develop in M. fortis. Extensive research has been carried out, however, the associated mechanism remains unclear. In the present study, we analysed the combined data obtained from a cytokine chip assay, transcri...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11532-2

    authors: Hu Y,Sun L,Yuan Z,Xu Y,Cao J

    更新日期:2017-09-12 00:00:00

  • Positive Cofactor 4 (PC4) is critical for DNA repair pathway re-routing in DT40 cells.

    abstract::PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28890

    authors: Caldwell RB,Braselmann H,Schoetz U,Heuer S,Scherthan H,Zitzelsberger H

    更新日期:2016-07-04 00:00:00