Abstract:
:Phytophthora blight is one of the most serious diseases affecting melon (Cucumis melo) production. Due to the lack of highly resistant germplasms, the progress on disease-resistant research is slow. To understand the genetics of melon resistance to Phytophthora capsici, an F2 population containing 498 individuals was developed by crossing susceptible line E31 to highly resistant line ZQK9. Genetic analysis indicated that the resistance in ZQK9 was controlled by a dominant gene, tentatively named MePhyto. Through bulked-segregant analysis (BSA-Seq) and chromosome walking techniques, the MePhyto gene was mapped to a 52.44 kb interval on chromosome 12. In this region, there were eight genes and their expression patterns were validated by qRT-PCR. Among them, one wall-associated receptor kinase (WAK) gene MELO3C002430 was significantly induced in ZQK9 after P. capsici inoculation, but not in E31. Based on the non-synonymous mutation site in MELO3C002430, a cleaved amplified polymorphic sequence (CAPS) marker, CAPS2430, was developed and this maker was co-segregated with MePhyto in both F2 population and a collection of 36 melon accessions. Thus MELO3C002430 was considered as the candidate gene and CAPS2430 was a promising marker for marker-assisted selection (MAS) in breeding. These results lay a foundation for revealing the resistance mechanism of melon to P. capsici.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Wang P,Xu X,Zhao G,He Y,Hou C,Kong W,Zhang J,Liu S,Xu Y,Xu Zdoi
10.1038/s41598-020-77600-2subject
Has Abstractpub_date
2020-11-24 00:00:00pages
20456issue
1issn
2045-2322pii
10.1038/s41598-020-77600-2journal_volume
10pub_type
杂志文章abstract::Music and language are complex hierarchical systems in which individual elements are systematically combined to form larger, syntactic structures. Suggestions that music and language share syntactic processing resources have relied on evidence that syntactic violations in music interfere with syntactic processing in l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36076-x
更新日期:2018-12-17 00:00:00
abstract::Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles; earlier during oncogenesis it suppresses neoplastic transformation an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48420-w
更新日期:2019-08-20 00:00:00
abstract::Visual reasoning is critical in many complex visual tasks in medicine such as radiology or pathology. It is challenging to explicitly explain reasoning processes due to the dynamic nature of real-time human cognition. A deeper understanding of such reasoning processes is necessary for improving diagnostic accuracy and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77550-9
更新日期:2020-12-10 00:00:00
abstract::There is strong in vitro cell survival evidence that the relative biological effectiveness (RBE) of protons is variable, with dependence on factors such as linear energy transfer (LET) and dose. This is coupled with the growing in vivo evidence, from post-treatment image change analysis, of a variable RBE. Despite thi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56258-5
更新日期:2019-12-27 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-73944-x
更新日期:2020-10-09 00:00:00
abstract::Here we present an experimental as well as theoretical study of third-harmonic generation in tightly focused femtosecond filaments in air at the wavelength of [Formula: see text]. At low intensities, longitudinal phase matching is dominating in the formation of 3rd harmonics, whereas at higher intensities locked X-wav...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74263-x
更新日期:2020-10-15 00:00:00
abstract::Semi-arid ecosystems are key contributors to the global carbon cycle and may even dominate the inter-annual variability (IAV) and trends of the land carbon sink, driven largely by the El Niño-Southern Oscillation (ENSO). The linkages between dynamics of semi-arid ecosystems and climate at the hemispheric scale however...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42281
更新日期:2017-02-09 00:00:00
abstract::Motivational, cognitive and action goals are processed by distinct, topographically organized, corticostriatal circuits. We aimed to test whether processing in the striatum is under causal control by cortical regions in the human brain by investigating the effects of offline transcranial magnetic stimulation (TMS) ove...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21346-5
更新日期:2018-02-19 00:00:00
abstract::The lack of vaccines and antiviral treatment, along with the increasing number of cases of Zika virus (ZIKV) and Chikungunya virus (CHIKV) infections, emphasize the need for searching for new therapeutic strategies. In this context, the marine brown seaweed Canistrocarpus cervicornis has been proved to hold great anti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65357-7
更新日期:2020-05-19 00:00:00
abstract::Long non-coding RNAs (lncRNAs) regulate expression of protein-coding genes in cis through chromatin modifications including DNA methylation. Here we interrogated whether lncRNA genes may regulate transcription and methylation of their flanking or overlapping protein-coding genes in livers of mice exposed to a 12-week ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29993-4
更新日期:2018-08-01 00:00:00
abstract::The physiological, biochemical and functional differences between oxidative and glycolytic muscles play important roles in human metabolic health and in animal meat quality. To explore these differences, we determined the genome-wide landscape of DNA methylomes and their relationship with the mRNA and miRNA transcript...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32186
更新日期:2016-08-26 00:00:00
abstract::Hybrid carbon films composed of graphene film and porous carbon film may give full play to the advantages of both carbon materials, and have great potential for application in energy storage and conversion devices. Unfortunately, there are very few reports on fabrication of hybrid carbon films. Here we demonstrate a s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07050
更新日期:2014-11-14 00:00:00
abstract::Wholesale, unbiased assessment of Scandinavian electronic health-care databases offer a unique opportunity to reveal potentially important undiscovered drug side effects. We examined the short-term risk of acute myocardial infarction (AMI) associated with drugs prescribed in Norway or Sweden. We identified 24,584 and ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44641-1
更新日期:2019-06-04 00:00:00
abstract::Olive oil pomace (OOP) is a bio-waste rich in highly soluble polyphenols. OOP has been proposed as an additive in ruminant feeding to modulate rumen fermentations. Three groups of ewes were fed the following different diets: a control diet and two diets supplemented with OOP, obtained with a two-phase (OOP2) or three-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26713-w
更新日期:2018-05-31 00:00:00
abstract::Single-wall carbon nanotubes (SWCNTs) and Bi2Te3 nanoplates are very promising thermoelectric materials for energy harvesting. When these two materials are combined, the resulting nanocomposites exhibit high thermoelectric performance and excellent flexibility. However, simple mixing of these materials is not effectiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73808-4
更新日期:2020-10-12 00:00:00
abstract::Wolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway using Aedes aegypti mosquitoes trans-infected with a non-natural Wolbachia strain to reduce dengue virus transmission. Less is known about the imp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70745-0
更新日期:2020-08-14 00:00:00
abstract::We demonstrate the use of accelerated reactions with desorption electrospray ionization mass spectrometry (DESI-MS) as a tool for predicting the outcome of microfluidic reactions. DESI-MS was employed as a high throughput experimentation tool to provide qualitative predictions of reaction outcomes, so that vast region...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50638-7
更新日期:2019-10-14 00:00:00
abstract::CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04967-0
更新日期:2017-07-05 00:00:00
abstract::A top-down scalable method to produce flexible water and blood repellent tubes is introduced. The method is based on replication of overhanging nanostructures from an aluminum tube template to polydimethylsiloxane (PDMS) via atomic layer deposition (ALD) assisted sacrificial etching. The nanostructured PDMS/titania tu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16369-3
更新日期:2017-11-22 00:00:00
abstract::In this contribution, a semi-automatic segmentation algorithm for (medical) image analysis is presented. More precise, the approach belongs to the category of interactive contouring algorithms, which provide real-time feedback of the segmentation result. However, even with interactive real-time contouring approaches t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05164
更新日期:2014-06-04 00:00:00
abstract::Cardiopulmonary resuscitation (CPR) training and its quality are critical in improving the survival rate of cardiac arrest. This randomized controlled study investigated the efficacy of a newly developed CPR training program for the public in a Taiwanese setting. A total of 832 adults were randomized to either a tradi...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-020-67193-1
更新日期:2020-06-22 00:00:00
abstract::The most downstream elements of the Hippo pathway, the TEAD transcription factors, are regulated by several cofactors, such as Vg/VGLL1-3. Earlier findings on human VGLL1 and here on human VGLL3 show that these proteins interact with TEAD via a conserved amino acid motif called the TONDU domain. Surprisingly, our stud...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74584-x
更新日期:2020-10-15 00:00:00
abstract::A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41598-017-16210-x
更新日期:2017-11-23 00:00:00
abstract::In this paper, one kind of novel non-periodic spoof surface plasmon polaritons (SSPPs) with H-shaped cells is proposed. As we all know, the cutoff frequency exists inherently for the conventional comb-shaped SSPPs, which is a kind of periodic groove shape structures and fed by a conventional coplanar waveguide (CPW). ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20533-8
更新日期:2018-02-06 00:00:00
abstract::Adaptive responses to hypoxia regulate hepatic lipid metabolism, but their consequences in nonalcoholic fatty liver disease (NAFLD) are largely unknown. Here, we show that hypoxia inducible factor-1 (HIF-1), a key determinant of hypoxic adaptations, prevents excessive hepatic lipid accumulation in the progression of N...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32586-w
更新日期:2018-09-21 00:00:00
abstract::Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53833-8
更新日期:2019-11-21 00:00:00
abstract::Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial energy balance as subst...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13478-x
更新日期:2017-10-12 00:00:00
abstract::The etiology of insulin resistance in Type 1 Diabetes (T1D) is unknown, however it affects approximately 20% of T1D patients. Intramyocellular lipids (IMCL) have been identified as a mechanism of insulin resistance. We examined skeletal muscle of T1D rats to determine if alterations in lipid metabolism were evident an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26379
更新日期:2016-05-20 00:00:00
abstract::Microtus fortis exhibits natural resistance against Schistosoma japonicum, and the parasite cannot grow and develop in M. fortis. Extensive research has been carried out, however, the associated mechanism remains unclear. In the present study, we analysed the combined data obtained from a cytokine chip assay, transcri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11532-2
更新日期:2017-09-12 00:00:00
abstract::PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28890
更新日期:2016-07-04 00:00:00