Receptor-interacting serine/threonine kinase 1- and 3-dependent inflammation induced in lungs of chicken infected with Pasteurella multocida.

abstract：:Human milk delivers an array of bioactive components that safeguard infant growth and development and maintain healthy gut microbiota. Milk fat globule membrane (MFGM) is a biologically functional fraction of milk increasingly linked to beneficial outcomes in infants through protection from pathogens, modulation of th...

journal_title：Scientific reports

authors： He X,Parenti M,Grip T,Lönnerdal B,Timby N,Domellöf M,Hernell O,Slupsky CM

更新日期：2019-08-12 00:00:00

abstract：:Common estimates of external training intensity for resistance exercise do not incorporate inter-set recovery duration, and might not reflect the overall demands of training. This study aimed to assess novel metrics of exercise density (ED) during resistance exercise, and how these related to a physiological marker of...

journal_title：Scientific reports

authors： Marston KJ,Peiffer JJ,Newton MJ,Scott BR

更新日期：2017-07-17 00:00:00

abstract：:Peptides derived from the N-terminal heptad repeat (NHR) of HIV-1 gp41 can be potent inhibitors against viral entry when presented in a nonaggregating trimeric coiled-coil conformation via the introduction of exogenous trimerization motifs and intermolecular disulfide bonds. We recently discovered that crosslinking is...

journal_title：Scientific reports

authors： Wang C,Li X,Yu F,Lu L,Jiang X,Xu X,Wang H,Lai W,Zhang T,Zhang Z,Ye L,Jiang S,Liu K

更新日期：2016-08-26 00:00:00

abstract：:Transport of self-propelled particles in a two-dimensional (2D) separate channel is investigated in the presence of the combined forces. By applying an ac force, the particles will be trapped by the separate walls. A dc force produces the asymmetry of the system and induces the longitudinal directed transport. Due to ...

journal_title：Scientific reports

authors： Wu JC,Ai BQ

更新日期：2016-04-01 00:00:00

abstract：:Ultraviolet-B (UVB) radiation damages plants and decreases their growth and productivity. We previously demonstrated that UVB sensitivity varies widely among Asian rice (Oryza sativa L.) cultivars and that the activity of cyclobutane pyrimidine dimer (CPD) photolyase, which repairs UVB-induced CPDs, determines UVB sen...

journal_title：Scientific reports

authors： Mmbando GS,Teranishi M,Hidema J

更新日期：2020-02-21 00:00:00

abstract：:Channelrhodopsin-2 (ChR2)-based optogenetic technique has been increasingly applied to cardiovascular research. However, the potential effects of ChR2 protein overexpression on cardiomyocytes are not completely understood. The present work aimed to examine how the doxycycline-inducible lentiviral-mediated ChR2 express...

journal_title：Scientific reports

authors： Li Q,Ni RR,Hong H,Goh KY,Rossi M,Fast VG,Zhou L

更新日期：2017-05-08 00:00:00

abstract：:Groundwater aquifers are an essential source of drinking water, and must be protected against contamination. Phosphogypsum stacks originating from the processing of phosphate rock contain small amounts of radionuclides, such as 226Ra. In September 2016, a sinkhole located beneath a phosphogypsum stack collapsed under ...

journal_title：Scientific reports

authors： Sandhu D,Singh A,Duranceau SJ,Nam BH,Mayo T,Wang D

更新日期：2018-07-30 00:00:00

abstract：:Magnetic skyrmions are promising candidates for the next generation of spintronic devices due to their small size and topologically protected structure. One challenge for using these magnetic states in applications lies on controlling the nucleation process and stabilization that usually requires an external force. He...

journal_title：Scientific reports

authors： Brandão J,Dugato DA,Seeger RL,Denardin JC,Mori TJA,Cezar JC

更新日期：2019-03-11 00:00:00

abstract：:Autophagy is a major regulator of pancreatic beta cell homeostasis. Altered autophagic activity has been implicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic rodents. Here, we show that autophagy was induced in beta cells by either a high-fat diet or a combined high-fa...

journal_title：Scientific reports

authors： Sheng Q,Xiao X,Prasadan K,Chen C,Ming Y,Fusco J,Gangopadhyay NN,Ricks D,Gittes GK

更新日期：2017-11-27 00:00:00

abstract：:Three-dimensional ion and particle concentrations under hydrodynamic focusing in a Y-shaped square microchannel are numerically simulated to clarify the decrease of the ion concentration along the flow direction within the focused particle stream. The simulation model is theoretically governed by the laminar flow and ...

journal_title：Scientific reports

authors： Sato N,Kawashima D,Takei M

更新日期：2021-01-28 00:00:00

abstract：:Intraperitoneal administration of antibiotics together with peritoneal dialysis fluids (PDFs) remains the preferable route for treatment of peritoneal dialysis-related peritonitis. For home based therapy, antibiotic-containing PDFs are stored for up to two weeks and warmed up to body-temperature before administration....

journal_title：Scientific reports

authors： Kussmann M,Ferth A,Obermüller M,Pichler P,Zeitlinger M,Wiesholzer M,Burgmann H,Poeppl W,Reznicek G

更新日期：2019-04-24 00:00:00

abstract：:Changes in climate extremes pose far-reaching consequences to ecological processes and hydrologic cycles in alpine ecosystems of the arid mountain regions. Therefore, regional assessments in various climates and mountain regions are needed for understanding the uncertainties of the change trends for extreme climate ev...

journal_title：Scientific reports

authors： Lin P,He Z,Du J,Chen L,Zhu X,Li J

更新日期：2017-05-22 00:00:00

abstract：:The studies investigating the effects of green tea on blood pressure (BP) have generated inconsistent results. The aim of this study is to quantitatively evaluate the effects of green tea on BP control. PubMed, Embase, and the Cochrane Library (updated to March 2014) were searched for randomized controlled trials eval...

journal_title：Scientific reports

authors： Peng X,Zhou R,Wang B,Yu X,Yang X,Liu K,Mi M

更新日期：2014-09-01 00:00:00

abstract：:Analysing the link between terrestrial ecosystem productivity (i.e., Net Primary Productivity: NPP) and extreme climate conditions is vital in the context of increasing threats due to climate change. To reveal the impact of changing extreme conditions on NPP, a copula-based probabilistic model was developed, and the s...

journal_title：Scientific reports

authors： Jha S,Das J,Goyal MK

更新日期：2019-12-12 00:00:00

abstract：:Most pollination in large-scale agriculture is dependent on managed colonies of a single species, the honey bee Apis mellifera. More than 1 million hives are transported to California each year just to pollinate the almonds, and bees are trucked across the country for various cropping systems. Concerns have been raise...

journal_title：Scientific reports

authors： Simone-Finstrom M,Li-Byarlay H,Huang MH,Strand MK,Rueppell O,Tarpy DR

更新日期：2016-08-24 00:00:00

abstract：:HOX proteins interact with PBX and MEIS cofactors, which belong to the TALE-class of homeodomain (HD)-containing transcription factors. Although the formation of HOX-PBX complexes depends on a unique conserved HOX motif called hexapeptide (HX), the additional presence of MEIS induces a remodeling of the interaction, l...

journal_title：Scientific reports

authors： Dard A,Jia Y,Reboulet J,Bleicher F,Lavau C,Merabet S

更新日期：2019-04-05 00:00:00

abstract：:A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to power-law (ordered) and exponentially (disordered) distributed blocks (clusters). The approach is illustrated on the 24 human chromosome sequences...

journal_title：Scientific reports

authors： Carbone A

更新日期：2013-01-01 00:00:00

abstract：:Bacterial proteins exported to the cell surface play key cellular functions. However, despite the interest to study the localisation of surface proteins such as adhesins, transporters or hydrolases, monitoring their dynamics in live imaging remains challenging, due to the limited availability of fluorescent probes rem...

journal_title：Scientific reports

authors： Chekli Y,Peron-Cane C,Dell'Arciprete D,Allemand JF,Li C,Ghigo JM,Gautier A,Lebreton A,Desprat N,Beloin C

更新日期：2020-09-25 00:00:00

abstract：:We investigate temperature smearing effects on the electron-boson spectral density function (I(2)χ(ω)) obtained from optical data using a maximum entropy inversion method. We start with two simple model input I(2)χ(ω), calculate the optical scattering rates at selected temperatures using the model input spectral densi...

journal_title：Scientific reports

authors： Hwang J

更新日期：2016-03-31 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are an important family of catalytic enzymes that generate reactive oxygen species (ROS), which mediate the regulation of diverse cellular functions. Although phagocyte Nox2/gp91phox is closely associated with the activation of host innate immune respo...

journal_title：Scientific reports

authors： Kim JH,Lee J,Bae SJ,Kim Y,Park BJ,Choi JW,Kwon J,Cha GH,Yoo HJ,Jo EK,Bae YS,Lee YH,Yuk JM

更新日期：2017-07-25 00:00:00

abstract：:Graphene aerogels (GAs) with high mechanical strength, tunable density and volume have been prepared only via soaking graphene hydrogels (GHs) in ammonia solution. The density and volume of the obtained GAs are controlled by adjusting the concentration of ammonia solution. Although volume of the GAs decreases with inc...

journal_title：Scientific reports

authors： Han Z,Tang Z,Shen S,Zhao B,Zheng G,Yang J

更新日期：2014-05-22 00:00:00

abstract：:Epithelial-to-mesenchymal transition (EMT) is a biological process in which epithelial cells translate into a mesenchymal phenotype with invasive capacities, contributing to tumour progression, metastasis, and the acquisition of chemotherapy resistance. To identify new therapeutic targets for cancers, it is important ...

journal_title：Scientific reports

authors： Goto M,Osada S,Imagawa M,Nishizuka M

更新日期：2017-11-27 00:00:00

abstract：:Following facial nerve axotomy, nerve function is not fully restored even after reconstruction. This may be attributed to axon degeneration/neuronal death and sustained neuroinflammation. CD38 is an enzyme that catalyses the hydrolysis of nicotinamide adenine dinucleotide (NAD+) and is a candidate molecule for regulat...

journal_title：Scientific reports

authors： Takaso Y,Noda M,Hattori T,Roboon J,Hatano M,Sugimoto H,Brenner C,Yamamoto Y,Okamoto H,Higashida H,Ito M,Yoshizaki T,Hori O

更新日期：2020-10-20 00:00:00

abstract：:Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis and disease. We hypothesized that ultrafiltration followed by size exclusion chromatography (UF-SEC) provides well-matched concentrates of EVs and free secreted...

journal_title：Scientific reports

authors： Benedikter BJ,Bouwman FG,Vajen T,Heinzmann ACA,Grauls G,Mariman EC,Wouters EFM,Savelkoul PH,Lopez-Iglesias C,Koenen RR,Rohde GGU,Stassen FRM

更新日期：2017-11-10 00:00:00

abstract：:Macrophages play a crucial role in the control and elimination of invading Mycobacterium tuberculosis (Mtb), and also serve as the major residence for Mtb. However, the interaction between macrophages and Mtb remains to be clearly determined. Although long noncoding RNAs (lncRNAs) have emerged as key regulators in man...

journal_title：Scientific reports

authors： Yang X,Yang J,Wang J,Wen Q,Wang H,He J,Hu S,He W,Du X,Liu S,Ma L

更新日期：2016-12-14 00:00:00

abstract：:In comparison to genome-wide association studies (GWAS), there has been poor replication of gene expression studies in chronic obstructive pulmonary disease (COPD). We performed microarray gene expression profiling on a large sample of resected lung tissues from subjects with severe COPD. Comparing 111 COPD cases and ...

journal_title：Scientific reports

authors： Morrow JD,Zhou X,Lao T,Jiang Z,DeMeo DL,Cho MH,Qiu W,Cloonan S,Pinto-Plata V,Celli B,Marchetti N,Criner GJ,Bueno R,Washko GR,Glass K,Quackenbush J,Choi AM,Silverman EK,Hersh CP

更新日期：2017-03-13 00:00:00

abstract：:Kalata B1 has been demonstrated to have bioactivity relating to membrane disruption. In this study, we conducted coarse-grained molecular dynamics simulations to gain further insight into kB1 bioactivity. The simulations were performed at various concentrations of kB1 to capture the overall progression of its activity...

journal_title：Scientific reports

authors： Nawae W,Hannongbua S,Ruengjitchatchawalya M

更新日期：2014-02-03 00:00:00

abstract：:Machine learning algorithms have recently shown their precision and potential in many different use cases and fields of medicine. Most of the algorithms used are supervised and need a large quantity of labeled data to achieve high accuracy. Also, most applications of machine learning in medicine are attempts to mimic ...

journal_title：Scientific reports

authors： Zéboulon P,Debellemanière G,Gatinel D

更新日期：2020-10-12 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BM-MSCs) are used in tissue engineering because of their migration characters. However, BM-MSCs have limitations in terms of reaching injuries and self-renewal. Therefore, enhancement of BM-MSC migration is important for therapeutic applications. Here, we assessed whether galectin-3...

journal_title：Scientific reports

authors： Gao Q,Xia Y,Liu L,Huang L,Liu Y,Zhang X,Xu K,Wei J,Hu Y,Mu Y,Li K

更新日期：2016-05-24 00:00:00

abstract：:The definition of a precise illumination region is essential in many applications where the electromagnetic field should be confined in some specific volume. By using conventional structures, it is difficult to achieve an adequate confinement distance (or volume) with negligible levels of radiation leakage beyond it. ...

journal_title：Scientific reports

authors： Bonache J,Zamora G,Paredes F,Zuffanelli S,Aguilà P,Martín F

更新日期：2016-11-25 00:00:00