Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.

abstract：:A correction has been published and is appended to both the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Crollen V,Albouy G,Lepore F,Collignon O

更新日期：2017-12-04 00:00:00

abstract：:The ability of deep learning architectures to identify glaucomatous optic neuropathy (GON) in fundus photographs was evaluated. A large database of fundus photographs (n = 14,822) from a racially and ethnically diverse group of individuals (over 33% of African descent) was evaluated by expert reviewers and classified ...

journal_title：Scientific reports

authors： Christopher M,Belghith A,Bowd C,Proudfoot JA,Goldbaum MH,Weinreb RN,Girkin CA,Liebmann JM,Zangwill LM

更新日期：2018-11-12 00:00:00

abstract：:We report on a new colorimetric DNA detection method that takes advantage of the power of polymerase chain reaction (PCR) and the simplicity of the classic litmus test. The strategy makes use of a modified set of primers for PCR to facilitate ensuing manipulations of resultant DNA amplicons: their tagging with urease ...

journal_title：Scientific reports

authors： Chang D,Tram K,Li B,Feng Q,Shen Z,Lee CH,Salena BJ,Li Y

更新日期：2017-06-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Baiocchini A,Del Nonno F,Taibi C,Visco-Comandini U,D'Offizi G,Piacentini M,Falasca L

更新日期：2020-01-24 00:00:00

abstract：:This paper presents a digital elevation model (DEM) of the dunes found in the Lençóis Maranhenses National Park, an environmental protection area located in the Maranhão state (Brazil). The DEM supports the modeling studies of sand-dune evolution using multi-temporal satellite images and ground truth data, obtained th...

journal_title：Scientific reports

authors： Dos Santos ALS,Borges HP,Silva Junior CHL,Piedade Junior RN,da Silva Bezerra D

更新日期：2019-05-15 00:00:00

abstract：:Increased risk of comorbidities has been reported in Rheumatic and Musculoskeletal Diseases (RMD). We aimed to evaluate the prevalence and pattern of comorbidities in RMD patients nationwide, to identify multimorbidity clusters and to evaluate the gap between recommendations and real screening. Cross-sectional, multic...

journal_title：Scientific reports

authors： Ziade N,El Khoury B,Zoghbi M,Merheb G,Abi Karam G,Mroue' K,Messaykeh J

更新日期：2020-05-06 00:00:00

abstract：:Hesperiidae is one of the largest families of butterflies. Our knowledge of the higher systematics on hesperiids from China is still very limited. We infer the phylogenetic relationships of the subfamilies of Chinese skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (ND...

journal_title：Scientific reports

authors： Yuan X,Gao K,Yuan F,Wang P,Zhang Y

更新日期：2015-06-10 00:00:00

abstract：:William Adams (Miura Anjin) was an English navigator who sailed with a Dutch trading fleet to the far East and landed in Japan in 1600. He became a vassal under the Shogun, Tokugawa Ieyasu, was bestowed with a title, lands and swords, and became the first SAMURAI from England. "Miura" comes from the name of the territ...

journal_title：Scientific reports

authors： Mizuno F,Ishiya K,Matsushita M,Matsushita T,Hampson K,Hayashi M,Tokanai F,Kurosaki K,Ueda S

更新日期：2020-12-10 00:00:00

abstract：:The function of Forkhead box O 1 (FOXO1) and pSerine256-FOXO1 immunostaining in esophageal cancer is unclear. To clarify the prognostic role of nuclear FOXO1 and cytoplasmic pSerine256-FOXO1 immunostaining, a tissue microarray containing more than 600 esophageal cancers was analyzed. In non-neoplastic esophageal mucos...

journal_title：Scientific reports

authors： Grupp K,Uzunoglu FG,Melling N,Hofmann B,El Gammal AT,Grotelüschen R,Heumann A,Bellon E,Reeh M,Wolters-Eisfeld G,Ghabdan T,Nentwich M,Bachmann K,Bockhorn M,Bogoevski D,Izbicki JR,Kutup A

更新日期：2018-11-26 00:00:00

abstract：:Low pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour site, while sparing healthy tissues. To this end, pH-sensitive, hollow ZnO-nanocarriers loaded with paclitaxel were sy...

journal_title：Scientific reports

authors： Puvvada N,Rajput S,Kumar BNP,Sarkar S,Konar S,Brunt KR,Rao RR,Mazumdar A,Das SK,Basu R,Fisher PB,Mandal M,Pathak A

更新日期：2015-07-06 00:00:00

abstract：:Remarkable improvements in both structural and optical properties of wafer-scale hexagonal boron nitride (h-BN) films grown by metal-organic chemical vapor deposition (MOCVD) enabled by high-temperature post-growth annealing is presented. The enhanced crystallinity and homogeneity of the MOCVD-grown h-BN films grown a...

journal_title：Scientific reports

authors： Lee SH,Jeong H,Okello OFN,Xiao S,Moon S,Kim DY,Kim GY,Lo JI,Peng YC,Cheng BM,Miyake H,Choi SY,Kim JK

更新日期：2019-07-22 00:00:00

abstract：:The central dogma of molecular biology describes the translation of genetic information from mRNA to protein, but does not specify the quantitation or timing of this process across the genome. We have analyzed protein and gene expression in a diverse set of human tissues. To study concordance and discordance of gene a...

journal_title：Scientific reports

authors： Kosti I,Jain N,Aran D,Butte AJ,Sirota M

更新日期：2016-05-04 00:00:00

abstract：:Soybean seeds are an important source of vegetable oil and biomaterials. The content of individual triacylglycerol species (TAG) in soybean seeds is difficult to quantify in an accurate and rapid way. The present study establishes an approach to quantify TAG species in soybean seeds utilizing an electrospray ionizatio...

journal_title：Scientific reports

authors： Li M,Butka E,Wang X

更新日期：2014-10-10 00:00:00

abstract：:Despite the relevance of complex root microbial communities for plant health, growth and productivity, the molecular basis of these plant-microbe interactions is not well understood. Verrucomicrobia are cosmopolitans in the rhizosphere, nevertheless their adaptations and functions are enigmatic since the proportion of...

journal_title：Scientific reports

authors： Bünger W,Jiang X,Müller J,Hurek T,Reinhold-Hurek B

更新日期：2020-05-26 00:00:00

abstract：:Cold Syndrome and Hot Syndrome are thousand-year-old key therapeutic concepts in traditional Chinese medicine (TCM), which depict the loss of body homeostasis. However, the scientific basis of TCM Syndrome remains unclear due to limitations of current reductionist approaches. Here, we established a network balance mod...

journal_title：Scientific reports

authors： Li R,Ma T,Gu J,Liang X,Li S

更新日期：2013-01-01 00:00:00

abstract：:Phylogenetic incongruence has frequently been encountered among different molecular markers. Recent progress in molecular phylogenomics has provided detailed and important information for evolutionary biology and taxonomy. Here we focused on the freshwater viviparid snails (Cipangopaludina chinensis chinensis and C. c...

journal_title：Scientific reports

authors： Hirano T,Saito T,Tsunamoto Y,Koseki J,Ye B,Do VT,Miura O,Suyama Y,Chiba S

更新日期：2019-04-17 00:00:00

abstract：:The non-invasive high-resolution spatial mapping of cell metabolism within tissues could provide substantial advancements in assessing the efficacy of stem cell therapy and understanding tissue development. Here, using two-photon excited fluorescence microscopy, we elucidate the relationships among endogenous cell flu...

journal_title：Scientific reports

authors： Quinn KP,Sridharan GV,Hayden RS,Kaplan DL,Lee K,Georgakoudi I

更新日期：2013-12-05 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep40641. ...

journal_title：Scientific reports

authors： Shen J,Lv B,Luo L,He J,Mao C,Xi D,Ming F

更新日期：2017-08-29 00:00:00

abstract：:Floral transition and petal onset, as two main aspects of flower development, are crucial to rapeseed evolutionary success and yield formation. Currently, very little is known regarding the genetic architecture that regulates flowering time and petal morphogenesis in Brassica napus. In the present study, a genome-wide...

journal_title：Scientific reports

authors： Yu K,Wang X,Chen F,Chen S,Peng Q,Li H,Zhang W,Hu M,Chu P,Zhang J,Guan R

更新日期：2016-07-27 00:00:00

abstract：:Airway mucus overproduction is one of the most common symptoms of asthma that causes severe clinical outcomes in patients. Despite the effectiveness of general asthma therapies, specific treatments that prevent mucus overproduction in asthma patients remain lacking. Recent studies have found that activation of GABAA r...

journal_title：Scientific reports

authors： Shen ML,Wang CH,Lin CH,Zhou N,Kao ST,Wu DC

更新日期：2016-09-06 00:00:00

abstract：:In this paper, we prepared a novel structure to enhance the electroluminescence intensity from Si quantum dots/SiO2multilayers. An amorphous Si/SiO2 multilayer film was fabricated by plasma-enhanced chemical vapor deposition on a Pt nanoparticle (NP)-coated Si nanopillar array substrate. By thermal annealing, an embed...

journal_title：Scientific reports

authors： Li W,Wang S,Hu M,He S,Ge P,Wang J,Guo YY,Zhaowei L

更新日期：2015-07-03 00:00:00

abstract：:In December 2015, four violent explosive episodes from Mt. Etna's oldest summit crater, the Voragine, produced eruptive columns extending up to 15 km a.s.l. and significant fallout of tephra up to a hundred km from the vent. A combined textural and compositional study was carried out on pyroclasts from three of the fo...

journal_title：Scientific reports

authors： Pompilio M,Bertagnini A,Del Carlo P,Di Roberto A

更新日期：2017-07-06 00:00:00

abstract：:The Acer truncatum Bunge is a particular widespread forest tree species in northern China. VLCFAs are important to eukaryotes survival and play diverse roles throughout the development. So far, there are reports that the Acer truncatum seeds fatty acid (FA) rich in VLCFAs, but little is known about the physiological m...

journal_title：Scientific reports

authors： Wang R,Liu P,Fan J,Li L

更新日期：2018-10-19 00:00:00

abstract：:Visual field (VF) testing has usually been performed with the central gaze as a fixed point. Recent publications indicated optic nerve head deformations induced by optic nerve traction force can promote the progression of optic neuropathies, including glaucoma. We generated a new static test protocol that adds 6° addu...

journal_title：Scientific reports

authors： Shoji T,Mine I,Kumagai T,Kosaka A,Yoshikawa Y,Shinoda K

更新日期：2020-12-03 00:00:00

abstract：:Wave propagation is an important characteristic for pattern formation and pattern dynamics. To date, various waves in homogeneous media have been investigated extensively and have been understood to a great extent. However, the wave behaviors in heterogeneous media have been studied and understood much less. In this w...

journal_title：Scientific reports

authors： Cui X,Huang X,Hu G

更新日期：2016-05-04 00:00:00

abstract：:Understanding adipose tissue cellular heterogeneity and homeostasis is essential to comprehend the cell type dynamics in metabolic diseases. Cellular subpopulations in the adipose tissue have been related to disease development, but efforts towards characterizing the adipose tissue cell type composition are limited. H...

journal_title：Scientific reports

authors： Lenz M,Arts ICW,Peeters RLM,de Kok TM,Ertaylan G

更新日期：2020-06-26 00:00:00

abstract：:Brain imaging genetics intends to uncover associations between genetic markers and neuroimaging quantitative traits. Sparse canonical correlation analysis (SCCA) can discover bi-multivariate associations and select relevant features, and is becoming popular in imaging genetic studies. The L1-norm function is not only ...

journal_title：Scientific reports

authors： Du L,Liu K,Yao X,Yan J,Risacher SL,Han J,Guo L,Saykin AJ,Shen L,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2017-10-25 00:00:00

abstract：:Neurodevelopmental changes occur with asymmetric hearing loss, limiting binaural/spatial hearing and putting children at risk for social and educational challenges. These deficits may be mitigated by providing bilateral hearing in children through auditory prostheses. Effects on speech perception and spatial hearing w...

journal_title：Scientific reports

authors： Polonenko MJ,Papsin BC,Gordon KA

更新日期：2018-09-04 00:00:00

abstract：:The electrowetting lenses has attracted researchers in many fields, such as biology, beam shaping, and drug delivery. Previous research on electrowetting lens has focused on neither expanding the dynamic focal length range nor reducing the wavefront aberration. However, the properties with large numerical aperture and...

journal_title：Scientific reports

authors： Song X,Zhang H,Li D,Jia D,Liu T

更新日期：2020-10-01 00:00:00

abstract：:Networks are widely used as a tool for describing diverse real complex systems and have been successfully applied to many fields. The distance between networks is one of the most fundamental concepts for properly classifying real networks, detecting temporal changes in network structures, and effectively predicting th...

journal_title：Scientific reports

authors： Shimada Y,Hirata Y,Ikeguchi T,Aihara K

更新日期：2016-10-11 00:00:00