The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region.

abstract：:Hedgehog (Hh) signaling plays a broad role in the development of many organs including bone and teeth. It is noted that sustained Hh activity in osteoblasts negatively regulates postnatal development in mice. However, it remains unknown whether Hh signaling contributes to cementum formation. In this study, to define t...

journal_title：Scientific reports

authors： Choi H,Liu Y,Yang L,Cho ES

更新日期：2020-04-29 00:00:00

abstract：:Thermoelectric properties of Graphene nano-ribbons (GNRs) with nanopores (NPs) are explored for a range of pore dimensions in order to achieve a high performance two-dimensional nano-scale thermoelectric device. We reduce thermal conductivity of GNRs by introducing pores in them in order to enhance their thermoelectri...

journal_title：Scientific reports

authors： Hossain MS,Al-Dirini F,Hossain FM,Skafidas E

更新日期：2015-06-17 00:00:00

abstract：:In this study, we analyzed mutants of Clostridium acetobutylicum, an organism used in a broad range of industrial processes related to biofuel production, to facilitate future studies of bioreactor and bioprocess design and scale-up, which are very important research projects for industrial microbiology applications. ...

journal_title：Scientific reports

authors： Zhou X,Xu D,Jiang TT

更新日期：2017-01-03 00:00:00

abstract：:Transforming growth factor-β/Smad3 signaling plays a critical role in the process of chronic kidney disease (CKD), but targeting Smad3 systematically may cause autoimmune disease by impairing immunity. In this study, we used whole-transcriptome RNA-sequencing to identify the differential gene expression profile, gene ...

journal_title：Scientific reports

authors： Zhou Q,Xiong Y,Huang XR,Tang P,Yu X,Lan HY

更新日期：2015-12-09 00:00:00

abstract：:The prediction of drug-target interactions is a key step in the drug discovery process, which serves to identify new drugs or novel targets for existing drugs. However, experimental methods for predicting drug-target interactions are expensive and time-consuming. Therefore, the in silico prediction of drug-target inte...

journal_title：Scientific reports

authors： Kuang Q,Xu X,Li R,Dong Y,Li Y,Huang Z,Li Y,Li M

更新日期：2015-09-09 00:00:00

abstract：:Production of fly ash zeolites may be an attractive method for the utilization of solid wastes from the energy sector. Different methods of synthesis often yield a variety of zeolite types, thereby affecting the properties of the resulting materials. The attention paid to carbon dioxide emission reduction technologies...

journal_title：Scientific reports

authors： Czuma N,Casanova I,Baran P,Szczurowski J,Zarębska K

更新日期：2020-02-04 00:00:00

abstract：:The spread of multidrug resistance via mobile genetic elements is a major clinical and veterinary concern. Pathogenic Escherichia coli harbour antibiotic resistance and virulence genes mainly on plasmids, but also bacteriophages and hybrid phage-like plasmids. In this study, the genomes of three E. coli phage-like pla...

journal_title：Scientific reports

authors： Venturini C,Zingali T,Wyrsch ER,Bowring B,Iredell J,Partridge SR,Djordjevic SP

更新日期：2019-12-11 00:00:00

abstract：:Radiation weighting factor wR for photons and electrons has been defined as unity independently of the energy of the particles. However, the biological effects depend on the incident energies according to in vitro experimental data. In this study, we have quantified the energy concentration along electron tracks in te...

journal_title：Scientific reports

authors： Yachi Y,Yoshii Y,Matsuya Y,Mori R,Oikawa J,Date H

更新日期：2019-11-27 00:00:00

abstract：:The bilateral controlled NOT (CNOT) operation plays a key role in standard entanglement purification process, but the CNOT operation may not be the optimal joint operation in the sense that the output entanglement is maximized. In this paper, the CNOT operations in both the Schmidt-projection based entanglement concen...

journal_title：Scientific reports

authors： Kong FZ,Xia HZ,Yang M,Yang Q,Cao ZL

更新日期：2016-05-18 00:00:00

abstract：:Graphene, a honeycomb lattice of carbon atoms ruled by tight-binding interaction, exhibits extraordinary electronic properties due to the presence of Dirac cones within its band structure. These intriguing singularities have naturally motivated the discovery of their classical analogues. In this work, we present a gen...

journal_title：Scientific reports

authors： Yves S,Lemoult F,Fink M,Lerosey G

更新日期：2017-11-10 00:00:00

abstract：:Aryl nitriles are versatile compounds that can be synthesized via transition-metal-mediated cyanation of aryl halides. Most of the supported-heterogeneous catalysts are noble-metals based and there are very limited numbers of efficient non-noble metal based catalysts demonstrated for the cyanation of aryl halides. Her...

journal_title：Scientific reports

authors： Mayakrishnan G,Elayappan V,Kim IS,Chung IM

更新日期：2020-01-20 00:00:00

abstract：:Fourier ptychographic microscopy (FPM) is a novel computational coherent imaging technique for high space-bandwidth product imaging. Mathematically, Fourier ptychographic (FP) reconstruction can be implemented as a phase retrieval optimization process, in which we only obtain low resolution intensity images correspond...

journal_title：Scientific reports

authors： Bian L,Suo J,Chung J,Ou X,Yang C,Chen F,Dai Q

更新日期：2016-06-10 00:00:00

abstract：:Single nucleotide variations (SNVs) can result in loss or gain of protein functional sites. We analyzed the effects of SNVs on enzyme active sites, ligand binding sites, and various types of post translational modification (PTM) sites. We found that, for most types of protein functional sites, the SNV pattern differs ...

journal_title：Scientific reports

authors： Pan Y,Yan C,Hu Y,Fan Y,Pan Q,Wan Q,Torcivia-Rodriguez J,Mazumder R

更新日期：2017-02-08 00:00:00

abstract：:Attosecond (asec) X-ray free-electron laser (XFEL) has attracted considerable interest over the past years. Nowadays typical XFEL application experiments demand 1010-1011 photons per pulse, which corresponds to a peak power of terawatts (TW) in case of asec hard X-ray pulse. To the realization of such TW asec-XFEL pul...

journal_title：Scientific reports

authors： Shim CH,Parc YW,Kim DE

更新日期：2020-01-28 00:00:00

abstract：:We examine the spin-dependent manipulating of vector beams by tailoring the inhomogeneous polarization. The spin-dependent manipulating is attributed to the spin-dependent phase gradient in vector beams, which can be regarded as the intrinsic feature of inhomogeneous polarization. The desired polarization can be obtai...

journal_title：Scientific reports

authors： Zhou J,Zhang W,Liu Y,Ke Y,Liu Y,Luo H,Wen S

更新日期：2016-09-28 00:00:00

abstract：:The Hurst effect plays an important role in many areas such as physics, climate and finance. It describes the anomalous growth of range and constrains the behavior and predictability of these systems. The Hurst effect is frequently taken to be synonymous with Long-Range Dependence (LRD) and is typically assumed to be ...

journal_title：Scientific reports

authors： Franzke CL,Osprey SM,Davini P,Watkins NW

更新日期：2015-03-13 00:00:00

abstract：:The capacity of healthy adult listeners to accommodate to altered spectral cues to the source locations of broadband sounds has now been well documented. In recent years we have demonstrated that the degree and speed of accommodation are improved by using an integrated sensory-motor training protocol under anechoic co...

journal_title：Scientific reports

authors： Watson CJG,Carlile S,Kelly H,Balachandar K

更新日期：2017-09-14 00:00:00

abstract：:The bacterial flagellar hook connects the helical flagellar filament to the rotary motor at its base. Bending flexibility of the hook allows the helical filaments to form a bundle behind the cell body to produce thrust for bacterial motility. The hook protein FlgE shows considerable sequence and structural similaritie...

journal_title：Scientific reports

authors： Hiraoka KD,Morimoto YV,Inoue Y,Fujii T,Miyata T,Makino F,Minamino T,Namba K

更新日期：2017-04-21 00:00:00

abstract：:Owing to its high technological importance for optoelectronics, zinc oxide received much attention. In particular, the role of defects on its physical properties has been extensively studied as well as their thermodynamical stability. In particular, a large concentration of Zn vacancies in ZnO bulk materials is so far...

journal_title：Scientific reports

authors： Renaud A,Cario L,Rocquelfelte X,Deniard P,Gautron E,Faulques E,Das T,Cheviré F,Tessier F,Jobic S

更新日期：2015-09-03 00:00:00

abstract：:The gene separation anxiety (san) encodes Naa50/San, a N-terminal acetyltransferase required for chromosome segregation during mitosis. Although highly conserved among higher eukaryotes, the mitotic function of this enzyme is still poorly understood. Naa50/San was originally proposed to be required for centromeric sis...

journal_title：Scientific reports

authors： Ribeiro AL,Silva RD,Foyn H,Tiago MN,Rathore OS,Arnesen T,Martinho RG

更新日期：2016-12-20 00:00:00

abstract：:Tumor oxygenation has been correlated with treatment outcome for radiotherapy. In this work, the dependence of tumor oxygenation on tumor vascularity and blood oxygenation was determined quantitatively in a 4D stochastic computational model of head and neck squamous cell carcinoma (HNSCC) tumor growth and angiogenesis...

journal_title：Scientific reports

authors： Forster JC,Douglass MJJ,Harriss-Phillips WM,Bezak E

更新日期：2017-09-08 00:00:00

abstract：:This retrospective cohort study investigated the association between in-hospital survival and two-dimensional (2D) echocardiography within 24 hours after the return of spontaneous circulation (ROSC) in patients who underwent in-hospital cardiopulmonary resuscitation (ICPR) after in-hospital cardiopulmonary arrest (IHC...

journal_title：Scientific reports

authors： Song IA,Cha JK,Oh TK,Jo YH,Yoon YE

更新日期：2020-01-08 00:00:00

abstract：:Histological chorioamnionitis (HCA) is an infection of fetal membranes and complicates 5.2% to 28.5% of all live births. HCA is associated with increased mortality and morbidity in both premature and term neonates. Exposure to HCA may have long-term consequences, including an increased risk for allergic disorders and ...

journal_title：Scientific reports

authors： Gayen Nee' Betal S,Murthy S,Favara M,Fong G,Chan JSY,Addya S,Shaffer TH,Greenspan J,Bhandari V,Rahman I,Aghai ZH

更新日期：2019-04-10 00:00:00

abstract：:Antibody based bio-molecular drugs are an exciting, new avenue of drug development as an alternative to the more traditional small chemical compounds. However, the binding mechanism and the effect on the conformational ensembles of a therapeutic antibody to its peptide or protein antigen have not yet been well studied...

journal_title：Scientific reports

authors： Bekker GJ,Fukuda I,Higo J,Kamiya N

更新日期：2020-01-29 00:00:00

abstract：:The development of effective central nervous system (CNS) drugs has been hampered by the lack of robust strategies to mimic the blood-brain barrier (BBB) and cerebrovascular impairments in vitro. Recent technological advancements in BBB modeling using induced pluripotent stem cells (iPSCs) allowed to overcome some of ...

journal_title：Scientific reports

authors： Roux GL,Jarray R,Guyot AC,Pavoni S,Costa N,Théodoro F,Nassor F,Pruvost A,Tournier N,Kiyan Y,Langer O,Yates F,Deslys JP,Mabondzo A

更新日期：2019-11-05 00:00:00

abstract：:Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...

journal_title：Scientific reports

authors： Glennon EKK,Megawati D,Torrevillas BK,Ssewanyana I,Huang L,Aweeka F,Greenhouse B,Adams LG,Luckhart S

更新日期：2018-06-11 00:00:00

abstract：:A series of three remarkable complexes [PMo12O40]@[Cu6O(TZI)3(H2O)9]4·OH·31H2O (H3TZI = 5-tetrazolylisophthalic acid; denoted as HLJU-1, HLJU = Heilongjiang University), [SiMo12O40]@[Cu6O(TZI)3(H2O)9]4·32H2O (denoted as HLJU-2), and [PW12O40]@[Cu6O(TZI)3(H2O)6]4·OH·31H2O (denoted as HLJU-3) have been isolated by using...

journal_title：Scientific reports

authors： Sun JW,Yan PF,An GH,Sha JQ,Li GM,Yang GY

更新日期：2016-05-09 00:00:00

abstract：:Antimicrobial stewardship programmes (ASP) are aimed at optimising antimicrobial utilization. However, only few studies have focused on paediatric intensive care units (PICU), where inappropriate antibiotic use occurs frequently. We assessed the effect and safety of a once weekly paediatric infectious disease (PID) wa...

journal_title：Scientific reports

authors： Renk H,Sarmisak E,Spott C,Kumpf M,Hofbeck M,Hölzl F

更新日期：2020-06-01 00:00:00

abstract：:Bisphenol A (BPA), a member of the environmental endocrine disruptors (EDCs), has recently received increased attention because of its effects on brain insulin resistance. Available data have indicated that brain insulin resistance may contribute to neurodegenerative diseases. However, the associated mechanisms that u...

journal_title：Scientific reports

authors： Wang T,Xie C,Yu P,Fang F,Zhu J,Cheng J,Gu A,Wang J,Xiao H

更新日期：2017-08-08 00:00:00

abstract：:A novel type of sub-lattice of the Jahn-Teller (JT) centers was arranged in Ti-doped barium hexaferrite BaFe12O19. In the un-doped crystal all iron ions, sitting in five different crystallographic positions, are Fe3+ in the high-spin configuration (S = 5/2) and have a non-degenerate ground state. We show that the elec...

journal_title：Scientific reports

authors： Gudkov VV,Sarychev MN,Zherlitsyn S,Zhevstovskikh IV,Averkiev NS,Vinnik DA,Gudkova SA,Niewa R,Dressel M,Alyabyeva LN,Gorshunov BP,Bersuker IB

更新日期：2020-04-27 00:00:00