Abstract:
:We report a case of polymorphous hemangioendothelioma, a rare vascular neoplasm, arising in the liver of a 51-year-old woman. Microscopically, this neoplasm is characterized by a polymorphous blend of solid, primitive vascular and angiomatous areas in variable proportions. Polymorphous hemangioendothelioma is considered to be an intermediate-grade vascular neoplasm. In most of the reported cases, its occurrence has been in lymph nodes, but a few cases have been found in extranodal sites such as the mediastinum, spinal cord, and liver. Its classification among other soft tissue neoplasms is still controversial due to an insufficient number of cases to allow prediction of its biologic behavior. The aim of this article is to report a rare case of extranodal hepatic polymorphous hemangioendothelioma primary to the liver and to offer a summary of the reported cases in the literature, with emphasis on the differential diagnosis and diagnostic pitfalls in daily practice.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
El Hussein S,Omarzai Ydoi
10.1177/1066896916679517subject
Has Abstractpub_date
2017-05-01 00:00:00pages
266-270issue
3eissn
1066-8969issn
1940-2465pii
1066896916679517journal_volume
25pub_type
杂志文章,评审abstract::Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916688307
更新日期:2017-06-01 00:00:00
abstract::Benign lymphoepithelial cyst (BLC) of the salivary gland is uncommon. Among report of these lesions, there were no previous cases of lymphoepithelial lesion (LeL) in human immunodeficiency virus type-1 (HIV-1) unrelated BLC. This study reports 3 cases of HIV-unrelated BLC containing LeL-like structures. Pathologically...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908328575
更新日期:2009-12-01 00:00:00
abstract::Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Case 1 involved a 91-year-old woman, who had hypertension and chr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896919879495
更新日期:2020-05-01 00:00:00
abstract:AIMS:Diffuse large B-cell lymphomas (DLBCL) can be divided into different subgroups (germinal center B-cell-like [GCB] and non-GCB) according to their gene expression profiles. Immunohistochemistry has been proposed as a surrogate for identifying these subgroups, but data about its efficacy in providing prognostic info...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909345596
更新日期:2011-08-01 00:00:00
abstract::Cystic squamous cell carcinomas (SCCs) of the jaws, including carcinoma cuniculatum, are rare, slow growing, and relentlessly invasive. The aim of this article is to present 12 cases, 4 of which were designated as carcinoma cuniculatum on the basis of deeply endophytic, anastomosing channels of cystic stratified squam...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920903388
更新日期:2020-09-01 00:00:00
abstract::Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET) are round-cell sarcomas with varying degrees of neuroectodermal differentiation; they are considered members of the same family of tumors based on their common genetic profile. ES/PNET are very infrequent in the female genital tract, the vagina being the ra...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896911424898
更新日期:2012-06-01 00:00:00
abstract::Pseudofungi are septate hyphae-like structures very similar morphologically to true fungal elements. Histologically their presence poses a diagnostic challenge as they mimic fungal infection. Accurate identification of pseudofungi is required to avoid unnecessary treatment, and this can be accomplished by careful morp...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916645185
更新日期:2016-09-01 00:00:00
abstract::Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909338597
更新日期:2010-08-01 00:00:00
abstract::The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912437414
更新日期:2012-08-01 00:00:00
abstract::Metanephric stromal tumor (MST) of the kidney is a rare pediatric neoplasm which has rarely been reported in adults. The authors present a case of MST, cellular type, an unreported variant, in a 56-year-old postmenopausal woman. The 9.0-cm tumor was solid, unencapsulated, and well circumscribed, with a firm homogeneou...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896912453851
更新日期:2013-04-01 00:00:00
abstract::Gastrointestinal stromal tumors (GIST) are the most common mesenchymal lesions of the gastrointestinal tract. Many are treated surgically with or without the use of adjuvant tyrosine kinase inhibitors. Metastases to lymph nodes are infrequent. In this article, we present a case of a perigastric nodule presenting 3 yea...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896918771192
更新日期:2018-10-01 00:00:00
abstract::Germinotropic lymphoproliferative disorder (GLPD) is a poorly characterized lymphoproliferative entity, recently included in the World Health Organization classification of hematolymphoid neoplasms. The histological pattern of this disease comprises monotypic plasmablasts that involve the germinal centers of the lymph...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920921238
更新日期:2020-10-01 00:00:00
abstract::Primary pulmonary acinic cell carcinoma (ACC) is rare. The clinicopathological features are not identical to that of classic ACC that leads to misdiagnosis. In this article, we summarized the clinicopathological features of 25 such cases, including 6 cases in this series and additional 19 cases in the literature. Pulm...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896919836499
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:To avoid diagnostic errors such as missed diagnosis and errors in staging tumors due to inadequate tissue sampling, pathologists submit additional sections (AS). OBJECTIVE:This study assessed frequency, diagnostic yield, distribution, and cost of AS. METHOD:Among 1542 AS cases, we calculated mean AS per ca...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918755008
更新日期:2018-08-01 00:00:00
abstract::Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917696744
更新日期:2017-08-01 00:00:00
abstract::Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similari...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896916675953
更新日期:2017-05-01 00:00:00
abstract::Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907304994
更新日期:2008-01-01 00:00:00
abstract::To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908318935
更新日期:2008-10-01 00:00:00
abstract::Dedifferentiated liposarcoma is typically a nonlipogenic high-grade sarcoma that arises from well-differentiated liposarcoma. It most commonly presents as a large mass in the retroperitoneum. Significant involvement of the gastrointestinal tract by dedifferentiated liposarcoma is uncommon. We present a unique case of ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917731517
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Benign neurogenic tumor involving the urinary bladder is a very rare and heterogeneous disease group. The clinical and radiological diagnosis may be difficult because of the disease's rarity and the histological similarities of each disease especially in needle biopsy specimens. However, accurate diagnosis i...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917742722
更新日期:2018-05-01 00:00:00
abstract::Sclerosing spindle cell rhabdomyosarcoma (SSRMS) is a newly recognized entity in adults. The authors report a new case of SSRMS in a 31-year-old woman who presented with a large right leg mass. Biopsy revealed a malignant spindle cell neoplasm with focal sclerotic areas. A diagnosis of monophasic synovial sarcoma was ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896908327166
更新日期:2010-10-01 00:00:00
abstract::Colorectal liver metastases with intrabiliary growth are uncommon and difficult to characterize by radiology alone. We present the case of a 61-year-old woman previously operated on for a left colon cancer who developed a metacronous lesion at liver segment II-III. Radiologic workup was indicative for cholangiocarcino...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896913491317
更新日期:2014-05-01 00:00:00
abstract::The rare reports of mucinous variant of follicular carcinoma of the thyroid gland have not provided enough evidence to support the recognition of these tumors as a distinct clinicopathologic entity or to understand their etiopathogenesis. We report the fourth case of mucinous variant of follicular carcinoma displaying...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896915617026
更新日期:2016-04-01 00:00:00
abstract::Mammary-type myofibroblastoma (MFB) is a benign spindle cell tumor of the breast and soft tissue characterized by 13q14 alterations leading to loss of Rb-1 protein expression, a feature shared among spindle cell lipoma and cellular angiofibroma. In this article, we present a novel case of MFB arising in the left breas...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920947465
更新日期:2020-08-05 00:00:00
abstract::Carcinomas in the breast with a predominantly clear cytoplasm are rare. In this article, we review the differential diagnosis of clear cell breast neoplasms and report a case of invasive lobular carcinoma with extensive clear cell morphology that was diagnosed as invasive ductal carcinoma, not otherwise specified, on ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896919881705
更新日期:2020-04-01 00:00:00
abstract::Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915597750
更新日期:2016-02-01 00:00:00
abstract::In this study based on the study of a centromeric DNA probe specific for chromosome 8 the authors standardized a method for the enzymatic detection of specific chromosome copy numbers on interphase nuclei from tumor tissue samples. Since the in situ hybridization (ISH) of chromosome 8 specific probe was revealed with ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800307
更新日期:2000-07-01 00:00:00
abstract::Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896914563392
更新日期:2015-06-01 00:00:00
abstract::Langerhans cell histiocytosis (LCH) with primary involvement of the upper gastrointestinal (GI) tract is rare. We report 2 adult cases of localized LCH in the upper-GI tract, including the second reported adult case of esophageal LCH and review 11 previously reported cases. Case 1 involved the esophagus of a 61-year-o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920964566
更新日期:2020-10-09 00:00:00
abstract::A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified. A microscopic examination of the nasopharyngeal ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896910371638
更新日期:2010-10-01 00:00:00