Abstract:
:Metanephric stromal tumor (MST) of the kidney is a rare pediatric neoplasm which has rarely been reported in adults. The authors present a case of MST, cellular type, an unreported variant, in a 56-year-old postmenopausal woman. The 9.0-cm tumor was solid, unencapsulated, and well circumscribed, with a firm homogeneous cut surface. The tumor was purely stromal with dense spindle-cell proliferations displaying prominent schwannoma-like architecture, intratumoral angiodysplasia, and entrapped native renal tubules with "onion-skin" tumor collarettes. The tumor stroma expressed CD34, estrogen, and progesterone and did not express desmin, smooth muscle actin, S-100, or TLE-1. Considering the characteristic morphology and immunophenotype, a diagnosis of "metanephric stromal tumor, cellular type," was made. This is an exceptionally rare disease manifestation in an adult patient and the first description of MST with such high stromal cellularity, making this case unique in both clinical and pathological presentation.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
Chaudhri AA,Lee L,Das Kdoi
10.1177/1066896912453851subject
Has Abstractpub_date
2013-04-01 00:00:00pages
153-60issue
2eissn
1066-8969issn
1940-2465pii
1066896912453851journal_volume
21pub_type
杂志文章,评审abstract::Cervical cancer is the most common gynecologic malignancy of the developing world. The oncogenic role of human papilloma virus (HPV) is well known. Attention is now focusing on the complicit genetic changes, which allow progression of these tumors. Regarding these changes, deletion of tumor suppressor genes (loss of h...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690301100402
更新日期:2003-10-01 00:00:00
abstract::Juvenile xanthogranuloma (JXG) is a benign histiocytic disorder usually affecting the head and trunk region of a child. The isolated occurrence of JXG in the penile shaft of a young adult is hitherto unreported. This lesion is amenable to surgical resection although systemic and/or internal visceral involvement can oc...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920916242
更新日期:2020-09-01 00:00:00
abstract::A rare case of primary pleomorphic liposarcoma of the thigh with a myxoid component, in which divergent differentiation to a well-differentiated chondrosarcoma was focally present, is described. Presence of heterologous elements has mainly been recognized in the context of dedifferentiated liposarcomas. Few cases of b...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690401200115
更新日期:2004-01-01 00:00:00
abstract::Mixed adenoneuroendocrine carcinomas (MANECs) of the biliary tract are rare tumors, and to date only a few cases arising in the gallbladder have been reported. Their histogenesis is a matter of debate, since the biliary tract normally lacks neuroendocrine cells. However, the immunohistochemical identification of nonne...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896915580433
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Study of minimum adenocarcinoma has been done almost exclusively on conventional acinar adenocarcinoma. Pseudohyperplastic adenocarcinoma can be confused with benign lesions because of its well-differentiated appearance and has not been studied when the biopsy shows few malignant glands (limited carcinoma). ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917715910
更新日期:2017-10-01 00:00:00
abstract::Fibroadenoma and phyllodes tumors of the breast exhibit a continuum of pathologic features. We examined phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumor on the first biopsy specimen. The phyllodes tumors initially called fibroadenoma for features tha...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907311378
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Phyllodes tumors (PTs) of the breast are rare biphasic neoplasms and are classified as benign, borderline, or malignant. Many biological markers have been studied to discriminate between different grades of PTs. IMP3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family and is ex...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915603119
更新日期:2016-02-01 00:00:00
abstract::Circulating tumor cells are rare in peripheral blood smears. We report the case of a patient with circulating breast carcinoma cells resembling circulating myeloid blasts and provide a brief review of the literature. Peripheral blood smears and a bone marrow aspirate were examined morphologically and by flow cytometry...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916664986
更新日期:2017-02-01 00:00:00
abstract::Synchronous tumors of the stomach are uncommon. We present a unique case of gastric synchronous tumors composed of signet-ring cell adenocarcinoma and gastrointestinal stromal tumor (GIST). The two tumors arose at the same site and were sharply juxtaposed without intermingling of morphologically distinct elements. Coi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907302369
更新日期:2007-10-01 00:00:00
abstract::We report a fourth case of papilliferous keratoameloblastoma, with a 6-year follow-up. A 62-year-old man underwent resection of a right mandibular neoplasm infiltrating bone and soft tissues. Microscopically, there were cysts lined by papillary projections and containing necrotic debris. Cribriform, solid, and tubular...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/106689690201000210
更新日期:2002-04-01 00:00:00
abstract::Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896907302423
更新日期:2007-07-01 00:00:00
abstract::Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916688307
更新日期:2017-06-01 00:00:00
abstract::The sarcomatoid variant of anaplastic large cell lymphoma is an extremely rare histologic pattern of anaplastic large cell lymphoma that consists of spindle-shaped neoplastic cells and is easily misdiagnosed as a soft tissue sarcoma. We report a case of the sarcomatoid variant of anaplastic large cell lymphoma that wa...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920986967
更新日期:2021-01-11 00:00:00
abstract::Dedifferentiated liposarcoma is typically a nonlipogenic high-grade sarcoma that arises from well-differentiated liposarcoma. It most commonly presents as a large mass in the retroperitoneum. Significant involvement of the gastrointestinal tract by dedifferentiated liposarcoma is uncommon. We present a unique case of ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917731517
更新日期:2018-04-01 00:00:00
abstract::In this study, the pathogenesis of clear cell change in colorectal epithelial lesions was studied. A total of 4 cases of clear cell change (1 hyperplasic polyp and 3 adenomas) were characterized using histochemistry, immunohistochemistry, and electron microscopy. All lesions developed in the left colon. In all, 1 aden...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908319211
更新日期:2009-12-01 00:00:00
abstract::Rhabdomyosarcoma is an aggressive malignant tumor often developing in the head and neck in children. In the sinonasal region, rhabdomyosarcoma constitutes a clinically important group because of the difficulty of surgical resection and its generally poor prognosis. We reviewed the archival pathology materials of 39 ca...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896906299122
更新日期:2007-04-01 00:00:00
abstract::Ocular sebaceous carcinoma is an uncommon, aggressive tumor arising from the Meibomian gland, Zeis gland, or sebaceous glands in the caruncle or eyelashes. We described a rare case of sebaceous carcinoma in situ in a 51-year-old female that was characterized by intraepithelial growth of sebaceous carcinoma cells with ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920917445
更新日期:2020-12-01 00:00:00
abstract::Atypical adenomatous hyperplasia (AAH) of the prostate is a microscopic proliferation of small acini that may be mistaken for adenocarcinoma. Although some data suggest that AAH is associated with adenocarcinoma arising in the transition zone, the clinical significance of this lesion is uncertain. Therefore we studied...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690501300207
更新日期:2005-04-01 00:00:00
abstract::Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912471851
更新日期:2013-04-01 00:00:00
abstract::To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908318935
更新日期:2008-10-01 00:00:00
abstract::Here we present the case of a 73-year-old woman with an ulcerated, advanced, hepatoid, and α-fetoprotein-producing poorly differentiated (G3) primary gastric adenocarcinoma pT3 N3a M1 with multinucleated cells and evident neuroendocrine component. This tumor was consistent with giant cell tumor type gastric carcinoma ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915586807
更新日期:2015-10-01 00:00:00
abstract::Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896909339912
更新日期:2011-12-01 00:00:00
abstract::A case of endobronchial pagetoid spread of a breast carcinoma metastatic to the lung is described. A 73-year-old woman underwent wedge lung resection after the cytological diagnosis of lung metastasis from ductal invasive breast carcinoma. The breast carcinoma had been surgically removed 6 years previously; at the tim...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916660619
更新日期:2017-02-01 00:00:00
abstract::Carcinomas in the breast with a predominantly clear cytoplasm are rare. In this article, we review the differential diagnosis of clear cell breast neoplasms and report a case of invasive lobular carcinoma with extensive clear cell morphology that was diagnosed as invasive ductal carcinoma, not otherwise specified, on ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896919881705
更新日期:2020-04-01 00:00:00
abstract::A completely infarcted lymph node should alert the pathologist to the high possibility of malignant lymphoma. The lymph node lesion of infectious mononucleosis (IM) shows marked histologic diversity and occasionally may be confused with malignant lymphoma. We report a rare case of IM showing extensive lymph node infar...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690201000312
更新日期:2002-07-01 00:00:00
abstract::Gastrointestinal stromal tumors (GIST) are the most common mesenchymal lesions of the gastrointestinal tract. Many are treated surgically with or without the use of adjuvant tyrosine kinase inhibitors. Metastases to lymph nodes are infrequent. In this article, we present a case of a perigastric nodule presenting 3 yea...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896918771192
更新日期:2018-10-01 00:00:00
abstract::Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912456081
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To assess the pathologic characteristics and prognostic significance of periprostatic lymph node (LN) metastasis of prostate cancer. The latter was performed by comparing biochemical recurrence (BCR)-free survival in cases of periprostatic LN metastasis versus matched patients showing pelvic LN metastasis. M...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896913482729
更新日期:2013-08-01 00:00:00
abstract::The aim of this study is to analyze all the cases of benign fibro-osseous lesions treated at School and Hospital of Stomatology, Wuhan University, to compare the results obtained in this study with those previously documented by other authors. The 127 cases diagnosed as a fibro-osseous lesion were retrieved, and infor...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896908318744
更新日期:2009-04-01 00:00:00
abstract::Primitive neuroepithelial differentiation in malignant peripheral nerve sheath tumors (MPNSTs) has been reported in children but is extremely rare in adults. The authors report the case of a 70-year-old woman who presented with swelling of the right leg of 1-month duration. Fine-needle aspiration cytology was suggesti...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911432453
更新日期:2012-10-01 00:00:00