Abundant hepatic Gaucher-like cells following chemotherapy and bone marrow transplantation for hematologic malignancy: report of two cases.

Abstract:

:Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron microscopy. Large numbers of Gaucher-like cells were found in the livers at autopsy of 2 patients with hematologic malignancy treated with chemotherapy and bone marrow transplant. Knowledge of this phenomenon may be useful in the interpretation of liver biopsy done on a patient with bone marrow transplant.

journal_name

Int J Surg Pathol

authors

Stenzel P,Weeks DA

doi

10.1177/1066896912456081

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

89-92

issue

1

eissn

1066-8969

issn

1940-2465

pii

1066896912456081

journal_volume

21

pub_type

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