Intralymphatic Histiocytosis of the Appendix and Fallopian Tube Associated With Primary Peritoneal High-Grade, Poorly Differentiated Adenocarcinoma of Müllerian Origin.

Abstract:

:Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literature. To date, ILH has not been described in an internal visceral organ. We report the case of a 68-year-old woman who underwent an appendectomy during a surgical procedure for a primary peritoneal high-grade, poorly differentiated adenocarcinoma of Müllerian origin. Although no malignancy was identified in the appendix, the appendiceal mucosa and submucosa were expanded by dilated vascular channels harboring aggregates of uniform epithelioid cells. Similar histological changes were also identified in the right fallopian tube. Immunohistochemical studies revealed the lymphatic nature of the vessels and the histiocytic origin of the intravascular cells. Of note was the presence of scattered multinucleated giant cells in the histiocytic population, a histological feature not described hitherto in ILH. To the best of the authors' knowledge, this is the first case of ILH harboring multinucleated giant cells, involving internal visceral organs, and associated with a malignant tumor of the gynecological system. As such, the current case report expands the clinical and histological spectrum of ILH.

journal_name

Int J Surg Pathol

authors

Tran TAN,Tran Q,Carlson JA

doi

10.1177/1066896916688307

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

357-364

issue

4

eissn

1066-8969

issn

1940-2465

journal_volume

25

pub_type

杂志文章
  • Angiosarcoma in Collision With a Merkel Cell Carcinoma: Case Report and Literature Review.

    abstract::Merkel cell carcinoma (MCC) is a rare entity that most commonly arises from the skin. Angiosarcoma (AS) is a rare malignancy with a predilection for elderly males, has endothelial differentiation and a notoriously poor prognosis despite aggressive therapy. Herein, we report an angiosarcoma colliding with a MCC, in a p...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896919880260

    authors: Hacking S,Chavaria H,Khan L,Das K

    更新日期:2020-05-01 00:00:00

  • Proximal-Type Epithelioid Sarcoma: Report of an Unusual Case in the Uterine Cervix.

    abstract::Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917696744

    authors: Suárez-Zamora DA,Barrera-Herrera LE,Rodríguez-Urrego PA,Palau-Lázaro MA

    更新日期:2017-08-01 00:00:00

  • Hepatic rosai-dorfman disease with coincidental lymphoma: report of a case.

    abstract::Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908329590

    authors: Di Tommaso L,Rahal D,Bossi P,Roncalli M

    更新日期:2010-12-01 00:00:00

  • Head and neck mucosal malignant melanoma: clinicopathologic correlation with contemporary review of prognostic indicators.

    abstract::Unlike their cutaneous counterparts, head and neck mucosal malignant melanomas (HNMM) behave much more aggressively and their prognostic markers have not been fully elucidated. Therefore, the aim of this study was to review the clinicopathologic features of a contemporary series of primary HNMM, retrieved from archiva...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911417970

    authors: Kerr EH,Hameed O,Lewis JS Jr,Bartolucci AA,Wang D,Said-Al-Naief N

    更新日期:2012-02-01 00:00:00

  • Clinicopathologic Features of Benign Neurogenic Tumor of Urinary Bladder.

    abstract:BACKGROUND:Benign neurogenic tumor involving the urinary bladder is a very rare and heterogeneous disease group. The clinical and radiological diagnosis may be difficult because of the disease's rarity and the histological similarities of each disease especially in needle biopsy specimens. However, accurate diagnosis i...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917742722

    authors: Lee C,Kim B,Song B,Park JH,Moon KC

    更新日期:2018-05-01 00:00:00

  • Acute Appendicitis and Pneumatosis in a Duplicated Appendix With Schistosoma Remnants.

    abstract::Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915597750

    authors: Handra-Luca A,Bisseret D,Dragoescu E

    更新日期:2016-02-01 00:00:00

  • The Giemsa stain: its history and applications.

    abstract::Gustav Giemsa was born in Germany in 1867, worked mainly as a chemist, and died in 1948. The staining method, which carries his name, was designed primarily for the demonstration of parasites in malaria, but it was also employed in histology because of the high-quality staining of the chromatin and the nuclear membran...

    journal_title:International journal of surgical pathology

    pub_type: 传,历史文章,杂志文章

    doi:10.1177/1066896907302239

    authors: Barcia JJ

    更新日期:2007-07-01 00:00:00

  • Verruciform Xanthoma of the Esophagus: Two Case Reports With Review of the Literature.

    abstract::Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Case 1 involved a 91-year-old woman, who had hypertension and chr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896919879495

    authors: Noguchi H,Kitazono I,Hamada K,Tanaka T,Tasaki T,Shirahama H,Yamamoto Y,Tanimoto A

    更新日期:2020-05-01 00:00:00

  • Synovial Sarcoma Mimicking Pleomorphic Hyalinizing Angiectatic Tumor of Soft Parts: A Case Report.

    abstract::Synovial sarcoma is a high-grade sarcoma commonly affecting young adults. The sites of involvement include soft tissue near joints, lung, pleura, mediastinum, larynx, kidney, and buttocks. Histologic types include monophasic, biphasic, and undifferentiated. We report a unique case of synovial sarcoma with low-grade hi...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917723463

    authors: Gupta N,Kenan S,Kahn LB

    更新日期:2018-02-01 00:00:00

  • Renal cell carcinoma in children and young adults: clinicopathological, immunohistochemical, and VHL gene analysis of 46 cases with follow-up.

    abstract::To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896909354337

    authors: Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

    更新日期:2011-04-01 00:00:00

  • Pathologic and clinical features of Hodgkin lymphoma--like posttransplant lymphoproliferative disease.

    abstract::Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896909338597

    authors: Krishnamurthy S,Hassan A,Frater JL,Paessler ME,Kreisel FH

    更新日期:2010-08-01 00:00:00

  • Uterine glomeruloid hemangioma in a patient without POEMS syndrome.

    abstract::Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911429297

    authors: Giner F,Compañ A,Monteagudo C

    更新日期:2012-08-01 00:00:00

  • A Note of Caution: Variable Cytokeratin Staining in Sentinel Node Metastases.

    abstract::Sentinel lymph node biopsy is the current standard procedure used to stage patients with breast cancer. The best histological method in evaluating sentinel nodes is highly debated among institutions and is thus not standardized. The optimal histological analysis is a balance between comprehensive evaluation of the sen...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915596811

    authors: Zeng J,Alexander MA,Nimeh D,Darvishian F

    更新日期:2015-10-01 00:00:00

  • A Subcentimetric Nodule on the Penile Shaft.

    abstract::Juvenile xanthogranuloma (JXG) is a benign histiocytic disorder usually affecting the head and trunk region of a child. The isolated occurrence of JXG in the penile shaft of a young adult is hitherto unreported. This lesion is amenable to surgical resection although systemic and/or internal visceral involvement can oc...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920916242

    authors: Majumder R,Biswas D,Mishra TS,Mitra S

    更新日期:2020-09-01 00:00:00

  • Primary carcinoid tumor of the skin: a literature review.

    abstract::Primary carcinoid tumor of the skin (PCTS) is an uncommon indolent neoplasm, with 10 cases described in the literature. The tumors affect patients in the sixth to ninth decades of life (mean = 66.3 years) with an equal gender distribution and predilection for the head and trunk. They present as slowly enlarging nodule...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896913516672

    authors: Jedrych J,Pulitzer M

    更新日期:2014-04-01 00:00:00

  • Immunoexpression of Epithelial Mesenchymal Transition Proteins E-Cadherin, β-Catenin, and N-Cadherin in Oral Squamous Cell Carcinoma.

    abstract::Aims Epithelial mesenchymal transition (EMT) is a crucial process for acquisition of malignant phenotype, aggressiveness, and metastatic capacity in neoplasms. It is characterized by loss of epithelial markers and gain of mesenchymal markers. Studies on EMT and its potential association with the histological grading a...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916654763

    authors: Angadi PV,Patil PV,Angadi V,Mane D,Shekar S,Hallikerimath S,Kale AD,Kardesai SG

    更新日期:2016-12-01 00:00:00

  • Primary Sellar Rhabdomyosarcoma Arising in Association With a Pituitary Adenoma.

    abstract::Intrasellar rhabdomyosarcoma is rare, and when arising in collusion with an unrelated entity, can present a diagnostic pitfall. We describe a case of a 56-year-old woman who presented with right eye ptosis and a pituitary mass, which was resected and diagnosed as atypical pituitary adenoma. Because of residual disease...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916658955

    authors: Duncan VE,Nabors LB,Warren PP,Conry RM,Willey CD,Perry A,Riley KO,Hackney JR

    更新日期:2016-12-01 00:00:00

  • Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Warthin Tumor: Case Report and Literature Review.

    abstract::Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896917734371

    authors: Jawad H,McCarthy P,O'Leary G,Heffron CC

    更新日期:2018-05-01 00:00:00

  • Pseudofungi: A Diagnostic Pitfall.

    abstract::Pseudofungi are septate hyphae-like structures very similar morphologically to true fungal elements. Histologically their presence poses a diagnostic challenge as they mimic fungal infection. Accurate identification of pseudofungi is required to avoid unnecessary treatment, and this can be accomplished by careful morp...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916645185

    authors: Lyapichev KA,Agarwal AN,Rosenberg AE,Chapman JR

    更新日期:2016-09-01 00:00:00

  • Mucinous Variant of Follicular Carcinoma of the Thyroid Gland: Case Report and Review of the Literature.

    abstract::The rare reports of mucinous variant of follicular carcinoma of the thyroid gland have not provided enough evidence to support the recognition of these tumors as a distinct clinicopathologic entity or to understand their etiopathogenesis. We report the fourth case of mucinous variant of follicular carcinoma displaying...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896915617026

    authors: Squillaci S,Pitino A,Spairani C,Ferrari M,Carlon E,Cosimi MF

    更新日期:2016-04-01 00:00:00

  • Nodular Lymphocyte-Predominant Hodgkin Lymphoma in a Warthin Tumor of the Parotid Gland: A Case Report and Literature Review.

    abstract::Hodgkin lymphoma (HL) associated with Warthin tumor (WT) is extremely rare, accounting for only 3 cases of classical HLs. Here, we report for the first time the occurrence of a nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) involving the lymphoid stroma of a WT of the parotid gland. Pathogenesis of WT is cont...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896915582263

    authors: Di Napoli A,Mallel G,Bartolazzi A,Cavalieri E,Becelli R,Cippitelli C,Ruco L

    更新日期:2015-08-01 00:00:00

  • PAX--FKHR fusion genes and AChR-gamma in Chinese patients with rhabdomyosarcoma: diagnosis using formalin-fixed archival tissues.

    abstract::The majority of alveolar RMSs have t(2;13)(q35;q14) or (1:13)(p36;q14),which generate PAX3/7 -FKHR fusion genes. Here, the authors detected the PAX3/7-FKHR fusion transcripts in 17 formalin-fixed, paraffin-embedded RMSs and 26 other SRCTs using one-step RT-PCR. PAX3 -FKHR and PAX7-FKHR transcripts were positive in 4/8...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908323922

    authors: Chang B,Pang LJ,Qi Y,Liu CX,Cao Y,Li HA,Hu WH,Jiang JF,Zhang WJ,Li F

    更新日期:2009-02-01 00:00:00

  • Podoplanin and E-cadherin expression in preoperative incisional biopsies of oral squamous cell carcinoma is related to lymph node metastases.

    abstract::Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896912471851

    authors: Foschini MP,Leonardi E,Eusebi LH,Farnedi A,Poli T,Tarsitano A,Cocchi R,Marchetti C,Gentile L,Sesenna E,Marucci G,Montebugnoli L

    更新日期:2013-04-01 00:00:00

  • Male Breast Carcinoma: A Clinical and Pathological Review.

    abstract::Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similari...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896916675953

    authors: Javidiparsijani S,Rosen LE,Gattuso P

    更新日期:2017-05-01 00:00:00

  • Cytological Features of Palisaded Mammary-Type Myofibroblastoma.

    abstract::Palisaded mammary-type myofibroblastoma is a rare variant of benign stromal spindle cell tumor whose histological features are well known. Nevertheless, no cytological features have been reported to date. In this article, we describe the cytological features of a case of palisaded mammary-type myofibroblastoma in whic...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916665699

    authors: Fabbri VP,Damiani S,Baccarini P,Saguatti G,Cucchi MC,Foschini MP

    更新日期:2017-04-01 00:00:00

  • Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies.

    abstract::Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of l...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915622277

    authors: Jabbour MN,Tawil AN,Boulos FI

    更新日期:2016-04-01 00:00:00

  • Crystalloid Granuloma of Parotid Gland: A Case Report With Review of the Literature.

    abstract::Crystalloid granuloma (CG) of salivary gland is an extremely rare inflammatory disease, and only 6 cases have been reported in the English literature. CG is histologically characterized by a granulomatous reaction to amylase crystalloid deposition. A 73-year-old woman presented with a painful left neck mass. Computed ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896918791031

    authors: Motoda N,Onda M,Nakamizo M,Ohashi R,Okubo K,Naito Z

    更新日期:2019-04-01 00:00:00

  • IgG4-positive sclerosing cholangitis following autoimmune pancreatitis with deranged CA19.9.

    abstract::Sclerosing cholangitis is an autoimmune condition characterized by lymphocytic infiltration within the biliary epithelium leading to multifocal stricturing of the biliary tree. Primary sclerosing cholangitis (PSC) is the most common type encountered clinically. However, a similar process may occur in conjunction with ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908319777

    authors: Ong SL,Garcea G,Puls F,Richards C,Mulcahy K,Grant A,Dennison AR,Berry DP

    更新日期:2011-02-01 00:00:00

  • Epithelioid Hemangioendothelioma of the Bowel in Crohn's Disease: The First Reported Case.

    abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896918801527

    authors: Spasic S,Brcic I,Freire R,Garcia-Buitrago MT,Rosenberg AE

    更新日期:2019-06-01 00:00:00

  • Clinicopathologic analysis of 4 perivascular epithelioid cell tumors (PEComas) of the gastrointestinal tract.

    abstract::This study describes the clinical, histologic, and immunohistochemical features of four cases of GI PEComa. The size of the tumors ranged from 3.5 to 6.0cm in diameter, and all were located in wall of the large bowel. Microscopically, the tumors were characterized by an epithelioid arrangement of tumor cells, which ha...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908330481

    authors: Shi HY,Wei LX,Sun L,Guo AT

    更新日期:2010-08-01 00:00:00