Abstract:
:Crystalloid granuloma (CG) of salivary gland is an extremely rare inflammatory disease, and only 6 cases have been reported in the English literature. CG is histologically characterized by a granulomatous reaction to amylase crystalloid deposition. A 73-year-old woman presented with a painful left neck mass. Computed tomography depicted a mass located in the lower pole of the left parotid gland, suspicious for a tumoral lesion. Preoperative fine needle aspiration cytology found amylase crystalloid deposition with a few inflammatory cells. Surgical sections of the mass revealed formation of a granuloma containing abundant eosinophilic but glassy and transparent amorphous crystalloids, suggestive of α-amylase crystalloid. No neoplastic elements were detected. The case was eventually diagnosed with CG in the parotid gland. Our findings suggest that when we identify amylase crystalloids in fine needle aspiration cytology smears from the salivary gland, CG should be considered even if neoplasm is clinically or radiographically suspected.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
Motoda N,Onda M,Nakamizo M,Ohashi R,Okubo K,Naito Zdoi
10.1177/1066896918791031subject
Has Abstractpub_date
2019-04-01 00:00:00pages
216-220issue
2eissn
1066-8969issn
1940-2465journal_volume
27pub_type
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