Abstract:
:Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similarities with female breast carcinoma (FBC). This review will address the important clinical, histopathological, immunohistochemical and molecular features, genetics, management, and prognosis of MBC.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
Javidiparsijani S,Rosen LE,Gattuso Pdoi
10.1177/1066896916675953subject
Has Abstractpub_date
2017-05-01 00:00:00pages
200-205issue
3eissn
1066-8969issn
1940-2465pii
1066896916675953journal_volume
25pub_type
杂志文章,评审abstract::A 72-year-old man had a unilateral pleural effusion and multiple bilateral pulmonary nodules. Thoracoscopic biopsy revealed multiple discrete nodules in the pleura and lung. The latter consisted of tall columnar malignant cells arranged on alveolar surfaces in a lepidic growth pattern. Mucin filled the alveolar lumina...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896906290363
更新日期:2006-07-01 00:00:00
abstract::Mammary-type myofibroblastoma (MFB) is a benign spindle cell tumor of the breast and soft tissue characterized by 13q14 alterations leading to loss of Rb-1 protein expression, a feature shared among spindle cell lipoma and cellular angiofibroma. In this article, we present a novel case of MFB arising in the left breas...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920947465
更新日期:2020-08-05 00:00:00
abstract::Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912456081
更新日期:2013-02-01 00:00:00
abstract::Male endometriosis and endomyometriosis (also termed "uterus-like mass") are 2 unusual manifestations of endometriosis. We report a case of male endomyometriosis with immunohistochemical and molecular confirmation. A 52-year-old man presented with stabbing pelvic pain. Computed tomography scan showed a mass in the rig...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896913501385
更新日期:2014-08-01 00:00:00
abstract::Primitive neuroepithelial differentiation in malignant peripheral nerve sheath tumors (MPNSTs) has been reported in children but is extremely rare in adults. The authors report the case of a 70-year-old woman who presented with swelling of the right leg of 1-month duration. Fine-needle aspiration cytology was suggesti...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911432453
更新日期:2012-10-01 00:00:00
abstract::Infiltrating ductal carcinoma (IDC) occurs frequently in patients with lobular carcinoma in-situ (LCIS). LCIS is not thought to be the direct precursor of the invasive component. The authors analyzed 15 cases of coexisting LCIS and IDC and found ductal carcinoma in situ (DCIS) in 12. The DCIS and IDC were of similar g...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690100900206
更新日期:2001-04-01 00:00:00
abstract::A cystic swelling in the parotid gland should lead to a differential diagnosis that includes benign cystic lesion of the gland, benign tumors that are frequently associated with cystic degeneration or entirely cystic de novo, or even a malignant neoplasm. The case presented is that of a cystic parotid swelling of 2 ye...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912454918
更新日期:2013-04-01 00:00:00
abstract::Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916688307
更新日期:2017-06-01 00:00:00
abstract::To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908318935
更新日期:2008-10-01 00:00:00
abstract::PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911418204
更新日期:2012-02-01 00:00:00
abstract::Metanephric stromal tumor (MST) of the kidney is a rare pediatric neoplasm which has rarely been reported in adults. The authors present a case of MST, cellular type, an unreported variant, in a 56-year-old postmenopausal woman. The 9.0-cm tumor was solid, unencapsulated, and well circumscribed, with a firm homogeneou...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896912453851
更新日期:2013-04-01 00:00:00
abstract::Sclerosing cholangitis is an autoimmune condition characterized by lymphocytic infiltration within the biliary epithelium leading to multifocal stricturing of the biliary tree. Primary sclerosing cholangitis (PSC) is the most common type encountered clinically. However, a similar process may occur in conjunction with ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908319777
更新日期:2011-02-01 00:00:00
abstract::Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. We illustrate a case of MEC of the parotid in a 17-year-old female, in which all these features o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917724889
更新日期:2018-02-01 00:00:00
abstract::Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917696744
更新日期:2017-08-01 00:00:00
abstract::Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET) are round-cell sarcomas with varying degrees of neuroectodermal differentiation; they are considered members of the same family of tumors based on their common genetic profile. ES/PNET are very infrequent in the female genital tract, the vagina being the ra...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896911424898
更新日期:2012-06-01 00:00:00
abstract::Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907304994
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Phyllodes tumors (PTs) of the breast are rare biphasic neoplasms and are classified as benign, borderline, or malignant. Many biological markers have been studied to discriminate between different grades of PTs. IMP3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family and is ex...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915603119
更新日期:2016-02-01 00:00:00
abstract::Polyoma virus nephritis is increasingly being recognized as a cause of allograft dysfunction in renal transplant patients. We describe and illustrate the findings in a renal biopsy and a concurrent urine sample from a patient with polyoma virus nephritis. The urine cytology findings were highly suggestive of a tumor d...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800412
更新日期:2000-10-01 00:00:00
abstract::Merkel cell carcinoma (MCC) is a rare entity that most commonly arises from the skin. Angiosarcoma (AS) is a rare malignancy with a predilection for elderly males, has endothelial differentiation and a notoriously poor prognosis despite aggressive therapy. Herein, we report an angiosarcoma colliding with a MCC, in a p...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896919880260
更新日期:2020-05-01 00:00:00
abstract::We describe the case of a 62-year-old man with chronic irritation of the urinary bladder resulting in dysuria and hypogastric pain. Three neoplasms measuring 0.5, 1, and 1.5 cm, respectively, were observed by cystoscopy and removed by transurethral resection (TUR). Histologic examination showed a complex folding of sq...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800317
更新日期:2000-07-01 00:00:00
abstract::Gastrointestinal stromal tumors (GIST) are the most common mesenchymal lesions of the gastrointestinal tract. Many are treated surgically with or without the use of adjuvant tyrosine kinase inhibitors. Metastases to lymph nodes are infrequent. In this article, we present a case of a perigastric nodule presenting 3 yea...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896918771192
更新日期:2018-10-01 00:00:00
abstract::Primary leiomyosarcoma arising from the ovarian vein is extremely rare, with only 10 cases reported in the literature. We report on a case of leiomyosarcoma of the left ovarian vein in a 67-year-old woman who presented with abdominal discomfort. Pelvic ultrasound revealed a large, solid, irregular mass in close relati...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896916679888
更新日期:2017-06-01 00:00:00
abstract::Malakoplakia is a rare granulomatous disease that commonly involves the genitourinary tract, with the urinary bladder being the most frequently affected site. Grossly, malakoplakia can present as soft yellow plaques, nodules, bladder mass, or even without any visible lesion. In this article, we present a 74-year-old f...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915595464
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:In this study, we retrospectively evaluated cases of patients who had undergone appendectomy in our hospital and aimed to present the efficiency of diagnostic tests and demographic data of cases. Pathological reports were analyzed for the following parameters: age, gender, and pathological diagnosis. In addi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918784650
更新日期:2019-04-01 00:00:00
abstract::To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909354337
更新日期:2011-04-01 00:00:00
abstract::A high level of serum alpha-fetoprotein (AFP) is typically indicative of hepatocellular carcinoma in patients with liver lesions. In this article, we describe an exceptional case of intrahepatic cholangiocarcinoma that occurred in a 36-year-old man with a markedly elevated serum AFP level (12310.7 ng/mL). Histopatholo...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907304519
更新日期:2008-04-01 00:00:00
abstract::A 25-year-old patient presented with epigastric pain, which on gastric biopsy revealed the characteristic appearance of collagenous gastritis. There was a thick prominent subepithelial band that was confirmed to be collagen with a Masson's trichrome stain. There was associated Helicobacter pylori gastritis but no evid...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908329588
更新日期:2010-12-01 00:00:00
abstract::In this study based on the study of a centromeric DNA probe specific for chromosome 8 the authors standardized a method for the enzymatic detection of specific chromosome copy numbers on interphase nuclei from tumor tissue samples. Since the in situ hybridization (ISH) of chromosome 8 specific probe was revealed with ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800307
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Cysts of the jaws (JCs) are an important topic of oral pathology, but few epidemiological data are present in the literature, in particular about the potential of recurrence. The aim of this study was to describe a case series of JCs from a single institution, evaluating the frequency, the site, the age dist...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896914541000
更新日期:2014-12-01 00:00:00
abstract::A 45-year-old woman presented with a short history of abdominal distension and features of intestinal obstruction. Computed tomography examination of the abdomen revealed a solid and cystic mass in the region of the left ovary, but spread within the abdomen was also noted. The ovarian tumor was removed, and an omentec...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690100900411
更新日期:2001-10-01 00:00:00