Application of CARD-ISH for Assessment of Numerical Chromosome Aberrations in Interphase Nuclei of Human Tumor Cells.

Abstract:

:In this study based on the study of a centromeric DNA probe specific for chromosome 8 the authors standardized a method for the enzymatic detection of specific chromosome copy numbers on interphase nuclei from tumor tissue samples. Since the in situ hybridization (ISH) of chromosome 8 specific probe was revealed with a catalyzed reporter deposition (CARD), which allows a high amplification of the hybridization signal, the method was designated as CARD-ISH. This method has been standardized on interphase nuclei isolated from clinical samples of pituitary adenomas, as well as on human normal lymphocytes. On the same samples, they also evaluated chromosome 8 copy number distribution by FISH. Comparison between CARD-ISH and FISH results showed no significant differences between the two methods, proposing CARD-ISH as a reliable alternative to FISH for chromosome numerical aberration assessment in laboratories that do not have specific facilities for epifluorescence microscopy or cytogenetics and that need a long-term storage of slides that had been used for diagnostic purposes. Int J Surg Pathol 8(3):201-206, 2000

journal_name

Int J Surg Pathol

authors

Buonamici L,Serra M,Losi L,Eusebi V

doi

10.1177/106689690000800307

keywords:

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

201-206

issue

3

eissn

1066-8969

issn

1940-2465

journal_volume

8

pub_type

杂志文章
  • Epithelioid Hemangioendothelioma of the Bowel in Crohn's Disease: The First Reported Case.

    abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896918801527

    authors: Spasic S,Brcic I,Freire R,Garcia-Buitrago MT,Rosenberg AE

    更新日期:2019-06-01 00:00:00

  • Primary Mixed Adenoneuroendocrine Carcinoma of the Gallbladder in a 55-Year-Old Female Patient: A Case Report and Review of the Literature.

    abstract::Mixed adenoneuroendocrine carcinomas (MANECs) of the biliary tract are rare tumors, and to date only a few cases arising in the gallbladder have been reported. Their histogenesis is a matter of debate, since the biliary tract normally lacks neuroendocrine cells. However, the immunohistochemical identification of nonne...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896915580433

    authors: Acosta AM,Hamedani FS,Kajdacsy-Balla A,Wiley EL

    更新日期:2015-08-01 00:00:00

  • Crystalloid Granuloma of Parotid Gland: A Case Report With Review of the Literature.

    abstract::Crystalloid granuloma (CG) of salivary gland is an extremely rare inflammatory disease, and only 6 cases have been reported in the English literature. CG is histologically characterized by a granulomatous reaction to amylase crystalloid deposition. A 73-year-old woman presented with a painful left neck mass. Computed ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896918791031

    authors: Motoda N,Onda M,Nakamizo M,Ohashi R,Okubo K,Naito Z

    更新日期:2019-04-01 00:00:00

  • Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases.

    abstract:BACKGROUND:In this study, we retrospectively evaluated cases of patients who had undergone appendectomy in our hospital and aimed to present the efficiency of diagnostic tests and demographic data of cases. Pathological reports were analyzed for the following parameters: age, gender, and pathological diagnosis. In addi...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896918784650

    authors: Unver N,Coban G,Arıcı DS,Buyukpınarbasılı N,Gucin Z,Malya FÜ,Onaran OI,Topalan K

    更新日期:2019-04-01 00:00:00

  • Mucosal Schwann Cell Hamartoma of the Rectosigmoid Junction: A Rare Lesion Mimicking Mucosal Prolapse Syndrome and Other Neural Lesions.

    abstract::In this article, we report the case of a 40-year-old woman with a sessile polyp of the rectosigmoid junction that underwent endoscopic resection. The resected specimen showed spindle cell proliferation with eosinophilic cytoplasm between mucosal crypts, mimicking mucosal prolapse syndrome. However, these were immunohi...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896918818897

    authors: Hashimoto H,Usui G,Sakai E,Ohata K,Morikawa T

    更新日期:2019-08-01 00:00:00

  • Lung adenocarcinoma metastasizing into a renal angiomyolipoma.

    abstract::Tumor-to-tumor metastasis is a very rare phenomenon. The most common donor and recipient of tumor-to-tumor metastasis are carcinomas of lung and renal cell carcinoma, respectively. We report a case of primary lung adenocarcinoma that metastasized into a renal angiomyolipoma 9 years after the resection of primary lung ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915572224

    authors: Wu PS,Pan CC

    更新日期:2015-05-01 00:00:00

  • Xp11.2 Translocation renal cell carcinomas have a poorer prognosis than non-Xp11.2 translocation carcinomas in children and young adults: a meta-analysis.

    abstract:OBJECTIVES:Renal cell carcinomas (RCCs) in children and adolescents are much rarer than in adults. In this age group, Xp11.2 translocation RCCs were the most common subtype of pediatric RCCs. Information regarding the clinical behavior of pediatric RCCs remains controversial because of their relatively rare incidence. ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,meta分析

    doi:10.1177/1066896910375565

    authors: Qiu Rao,Bing Guan,Zhou XJ

    更新日期:2010-12-01 00:00:00

  • Clear cell change in colonic polyps.

    abstract::In this study, the pathogenesis of clear cell change in colorectal epithelial lesions was studied. A total of 4 cases of clear cell change (1 hyperplasic polyp and 3 adenomas) were characterized using histochemistry, immunohistochemistry, and electron microscopy. All lesions developed in the left colon. In all, 1 aden...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908319211

    authors: Eloy C,Lopes JM,Faria G,Moreira H,Brandão A,Silva T,Carneiro F

    更新日期:2009-12-01 00:00:00

  • Cutaneous melanoma metastatic to uterine adenomyoma: report of a case.

    abstract::Rare cases of metastasis to uterine polyps have been reported in English literature but not, to the best of our knowledge, to uterine adenomyomas. All these cases are represented by breast cancer, most of them involving tamoxifen-associated polyps. We first report a case of cutaneous malignant melanoma metastatic to u...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690501300217

    authors: Di Tommaso L,Rahal D,Bresciani G,Roncalli M

    更新日期:2005-04-01 00:00:00

  • Unsuspected Xp11 Translocation Renal Neoplasm Associated With Contralateral Clear Cell Carcinoma.

    abstract::In this report, we present for the first time the coexistence of a conventional renal cell carcinoma (RCC) and an undefined Xp11 translocation renal neoplasm in distinct kidneys, which was difficult to definitively classify as either carcinoma or PEComa (perivascular epithelioid cell tumor). While one of the tumors sh...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915597753

    authors: D'Antonio A,Addesso M,Nappi O,Zeppa P

    更新日期:2016-05-01 00:00:00

  • Cystic Squamous Cell Carcinomas of the Jaws: Twelve Cases Highlighting Histopathological Pitfalls.

    abstract::Cystic squamous cell carcinomas (SCCs) of the jaws, including carcinoma cuniculatum, are rare, slow growing, and relentlessly invasive. The aim of this article is to present 12 cases, 4 of which were designated as carcinoma cuniculatum on the basis of deeply endophytic, anastomosing channels of cystic stratified squam...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920903388

    authors: Barrett AW,Garg M,Armstrong D,Bisase BS,Newman L,Norris PM,Shelley M,Tighe JV,Hyde NC,Chaston NJ,Gulati A

    更新日期:2020-09-01 00:00:00

  • Uterine glomeruloid hemangioma in a patient without POEMS syndrome.

    abstract::Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911429297

    authors: Giner F,Compañ A,Monteagudo C

    更新日期:2012-08-01 00:00:00

  • Immunoexpression of Epithelial Mesenchymal Transition Proteins E-Cadherin, β-Catenin, and N-Cadherin in Oral Squamous Cell Carcinoma.

    abstract::Aims Epithelial mesenchymal transition (EMT) is a crucial process for acquisition of malignant phenotype, aggressiveness, and metastatic capacity in neoplasms. It is characterized by loss of epithelial markers and gain of mesenchymal markers. Studies on EMT and its potential association with the histological grading a...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916654763

    authors: Angadi PV,Patil PV,Angadi V,Mane D,Shekar S,Hallikerimath S,Kale AD,Kardesai SG

    更新日期:2016-12-01 00:00:00

  • Follicular Cholecystitis: Reappraisal of Incidence, Definition, and Clinicopathologic Associations in an Analysis of 2550 Cholecystectomies.

    abstract:CONTEXT.:Follicular cholecystitis (FC) is a poorly characterized entity. OBJECTIVE.:To determine its frequency/clinicopathologic associations. DESIGN.:A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic exami...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920924079

    authors: Saka B,Memis B,Seven IE,Pehlivanoglu B,Balci S,Bagci P,Reid M,Dursun N,Escalano OT,Roa JC,Araya JC,Kong SY,Basturk O,Koshiol J,Adsay NV

    更新日期:2020-12-01 00:00:00

  • Palisaded Encapsulated (Solitary Circumscribed) Neuroma: A Review of 30 Cases.

    abstract::Background. Solitary circumscribed neuroma (SCN), also known as palisaded encapsulated neuroma (PEN), is a benign neural tumor. It may be mistaken as either schwannoma or neurofibroma in pathology practice. In this study, we aimed to define clinicopathologic and immunohistochemical features and discuss its differentia...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896919833172

    authors: Leblebici C,Savli TC,Yeni B,Cin M,Aksu AEK

    更新日期:2019-08-01 00:00:00

  • UbcH10 expression in benign, hyperplastic, and malignant endometrial curetted materials: a tissue microarray study.

    abstract::The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896912437414

    authors: Kefeli M,Yildiz L,Celik H,Tosun M,Karagoz F

    更新日期:2012-08-01 00:00:00

  • Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Warthin Tumor: Case Report and Literature Review.

    abstract::Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896917734371

    authors: Jawad H,McCarthy P,O'Leary G,Heffron CC

    更新日期:2018-05-01 00:00:00

  • Collagenous gastritis.

    abstract::A 25-year-old patient presented with epigastric pain, which on gastric biopsy revealed the characteristic appearance of collagenous gastritis. There was a thick prominent subepithelial band that was confirmed to be collagen with a Masson's trichrome stain. There was associated Helicobacter pylori gastritis but no evid...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908329588

    authors: Jain R,Chetty R

    更新日期:2010-12-01 00:00:00

  • Well-differentiated chondrosarcoma of the humerus with prominent granular cell component: a hitherto unreported occurrence.

    abstract::We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690601400211

    authors: Cremonini A,Kuhn E,De Biase P,Franchi A

    更新日期:2006-04-01 00:00:00

  • Autoimmune-Like Hepatitis: A "Hepatitic" Manifestation of Chronic Graft Versus Host Disease in Post-Stem Cell Transplant.

    abstract::A 59-year-old female received a matched related donor stem cell transplant for chronic myelogenous leukemia. After being successfully treated with prednisone for chronic graft versus host disease that initially started 50 days posttransplant, she developed hepatic dysfunction during the steroid taper on day 531, as ev...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915610817

    authors: Baniak NM,Kanthan R

    更新日期:2016-04-01 00:00:00

  • A Practical Approach to Investigating Cross-Contaminants in the Anatomical Pathology Laboratory.

    abstract::Tissue contaminants in anatomical pathology are not uncommon. While issues related to the presence of extraneous tissue on glass slides are often easily resolved, this is not always the case and several factors may contribute to diagnostic difficulty. Because of this, familiarity with the different steps involved in h...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920913110

    authors: Hodgson AJ,Shang YM,Boulianne P,Downes MR,Hwang D,Slodkowska E

    更新日期:2020-10-01 00:00:00

  • Anaplastic Sarcoma of the Kidney: A Rare Unique Renal Neoplasm.

    abstract::Anaplastic sarcoma of the kidney (ASK) is an extremely rare tumor, which usually presents as a large renal mass. Microscopically, the tumor is composed of pleomorphic mesenchymal spindle cells with marked atypia, associated with chondroid differentiation and focal round primitive mesenchymal cells. Herein, we present ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896916639373

    authors: Arabi H,Al-Maghraby H,Yamani A,Yousef Y,Huwait H

    更新日期:2016-09-01 00:00:00

  • Hepatic rosai-dorfman disease with coincidental lymphoma: report of a case.

    abstract::Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908329590

    authors: Di Tommaso L,Rahal D,Bossi P,Roncalli M

    更新日期:2010-12-01 00:00:00

  • Fuzeon-induced collagenophagic granuloma: a peculiar granulomatous injection site reaction to Fuzeon--a case report and review of literature.

    abstract::Enfuvirtide (ENF, T-20, or Fuzeon [Hoffman-La Roche Inc, Nutley, NJ, and Trimeris, Inc, Durham, NC]) is an HIV-1 fusion inhibitor and is the only injectable antiretroviral drug available. Injection site reactions (ISRs) are the most frequently reported adverse events, occurring in about 98% of patients. A granuloma an...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896909332119

    authors: Sidhu HK,Chaffee BH,Tvetenstrand CD,Sidhu JS

    更新日期:2010-10-01 00:00:00

  • Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies.

    abstract::Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of l...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915622277

    authors: Jabbour MN,Tawil AN,Boulos FI

    更新日期:2016-04-01 00:00:00

  • Significance of IMP3, nucleophosmin, and Ki-67 expression in papillary thyroid carcinoma.

    abstract::The purpose of our study was to investigate the diagnostic value of expression of IMP3, nucleophosmin, and correlation of these markers with Ki-67 proliferation index in papillary thyroid carcinoma and benign neoplasms of thyroid gland. The aim was also to investigate whether there is a difference between papillary an...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896914554832

    authors: Yorukoglu A,Yalcin N,Avci A,Cakalagaoglu F,Yaylali G,Akin F,Haciyanli M,Ozden A

    更新日期:2015-02-01 00:00:00

  • Spontaneous complete regression of gastric large-cell neuroendocrine carcinoma: mediated by cytomegalovirus-induced cross-autoimmunity?

    abstract::Spontaneous regression of malignant tumour is a rare phenomenon. This report describes such an occurrence in a gastric large cell neuroendocrine carcinoma of a 77-year-old man. The patient presented with dyspepsia, and biopsy of the fungating mass in the cardia showed a high grade neuroendocrine carcinoma. The pre-ope...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911404412

    authors: Ip YT,Pong WM,Kao SS,Chan JK

    更新日期:2011-06-01 00:00:00

  • Displaced epithelium after liposuction for gynecomastia.

    abstract::The authors describe the case of a 36-year-old man with gynecomastia who was previously treated with liposuction of the breast for cosmetic purposes. Histologic examination of a subsequent excisional biopsy revealed nests of displaced epithelial cells in adipose tissue. Epithelial cell displacement is a well-known ris...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896910362990

    authors: McLaughlin CS,Petrey C,Grant S,Ransdell JS,Reynolds C

    更新日期:2011-08-01 00:00:00

  • Adenomatous polyposis coli (APC) protein expression in primary and metastatic serous ovarian carcinoma.

    abstract::The aim of this study was to investigate protein expression of adenomatous polyposis coli (APC) in primary and metastatic serous ovarian carcinoma. The expression of beta-catenin and E-cadherin was additionally analyzed. One hundred and thirteen primary (n = 56) and metastatic (n = 57) lesions were immunohistochemical...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690201000302

    authors: Karbova E,Davidson B,Metodiev K,Tropé CG,Nesland JM

    更新日期:2002-07-01 00:00:00

  • Aberrant expression of alpha-fetoprotein in intrahepatic cholangiocarcinoma: an exceptional occurrence.

    abstract::A high level of serum alpha-fetoprotein (AFP) is typically indicative of hepatocellular carcinoma in patients with liver lesions. In this article, we describe an exceptional case of intrahepatic cholangiocarcinoma that occurred in a 36-year-old man with a markedly elevated serum AFP level (12310.7 ng/mL). Histopatholo...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896907304519

    authors: Vij K,Wang HL

    更新日期:2008-04-01 00:00:00