Significance of IMP3, nucleophosmin, and Ki-67 expression in papillary thyroid carcinoma.

abstract：BACKGROUND:Acetylcholinesterase (AchE) histochemistry has been established as an accurate diagnostic tool for Hirschsprung's disease (HD). In addition, calretinin immunohistochemistry is also reported as a reliable and adjunctive method to diagnose HD. We investigated the diagnostic value of combined AchE histochemistr...

journal_title：International journal of surgical pathology

authors： Jeong H,Jung HR,Hwang I,Kwon SY,Choe M,Kang YN,Jung E,Kim SP

更新日期：2018-09-01 00:00:00

abstract：:Goblet cell carcinoid (GCC) of the appendix is characterized by a dual differentiation of both endocrine and gland. This study, therefore, explores its clinicopathological and immunohistochemical features. The authors reviewed clinicopathological and immunohistochemical features of 26 GCC cases in Southwest China betw...

journal_title：International journal of surgical pathology

authors： Yong Jiang,Huawei Liu,Hu Long,Yingying Yang,Dianying Liao,Xiuhui Zhang

更新日期：2010-12-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:SMARCB1 (INI1) deficient sinonasal carcinoma is a recently recognized entity with wide histomorphologic spectrum. We present a case of this carcinoma that contained, in addition to a "common" morphology, scattered foci of yolk sac tumor differentiation. The tumor occurred in paranasal sinuses in a 44-year-old woman. I...

journal_title：International journal of surgical pathology

authors： Zamecnik M,Rychnovsky J,Syrovatka J

更新日期：2018-05-01 00:00:00

abstract：:Background. In this single-institution study, we applied the current (eighth edition) American Joint Committee on Cancer pathologic staging criteria to 64 low-grade mucinous neoplasms of the appendix (LAMNs), examined their histopathologic features, and studied the patients' clinical outcomes. Design. Sixty-four LAMNs...

journal_title：International journal of surgical pathology

authors： Wong M,Barrows B,Gangi A,Kim S,Mertens RB,Dhall D

更新日期：2020-05-01 00:00:00

abstract：:Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similari...

journal_title：International journal of surgical pathology

authors： Javidiparsijani S,Rosen LE,Gattuso P

更新日期：2017-05-01 00:00:00

abstract：:Eccrine porocarcinoma is a potentially fatal form of sweat gland carcinoma, due to its propensity to metastasize through lymph vessels. The authors report the case of a 69-year-old female who presented with swelling of the right leg and an ulcerated lesion of the right great toe. The initial histologic diagnosis was i...

journal_title：International journal of surgical pathology

authors： Ramirez Y,Fellegara G,Bugiani M

更新日期：2012-10-01 00:00:00

abstract：:Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma th...

journal_title：International journal of surgical pathology

authors： Lu Y,Milchgrub S,Khatri G,Gopal P

更新日期：2017-05-01 00:00:00

abstract：:Synchronous tumors of the stomach are uncommon. We present a unique case of gastric synchronous tumors composed of signet-ring cell adenocarcinoma and gastrointestinal stromal tumor (GIST). The two tumors arose at the same site and were sharply juxtaposed without intermingling of morphologically distinct elements. Coi...

journal_title：International journal of surgical pathology

authors： Lee FY,Jan YJ,Wang J,Yu CC,Wu CC

更新日期：2007-10-01 00:00:00

abstract：:Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

journal_title：International journal of surgical pathology

authors： Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

更新日期：2011-12-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) with primary involvement of the upper gastrointestinal (GI) tract is rare. We report 2 adult cases of localized LCH in the upper-GI tract, including the second reported adult case of esophageal LCH and review 11 previously reported cases. Case 1 involved the esophagus of a 61-year-o...

journal_title：International journal of surgical pathology

authors： Matsuoka Y,Iemura Y,Fujimoto M,Shibuya S,Yamada A,Fujii S,Kusaka T,Shindo T,Minamiguchi S,Haga H

更新日期：2020-10-09 00:00:00

abstract：:Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...

journal_title：International journal of surgical pathology

authors： Tran TAN,Tran Q,Carlson JA

更新日期：2017-06-01 00:00:00

abstract：:We review the clinical, pathologic, and molecular genetic features of 3 splenic T-cell-rich B-cell lymphomas and discuss their differential diagnosis. All patients presented with symptomatic splenomegaly and underwent diagnostic/therapeutic splenectomy. Microscopically, the spleen in all cases showed a micronodular pr...

journal_title：International journal of surgical pathology

authors： Li S,Mann KP,Holden JT

更新日期：2004-01-01 00:00:00

abstract：:Pseudofungi are septate hyphae-like structures very similar morphologically to true fungal elements. Histologically their presence poses a diagnostic challenge as they mimic fungal infection. Accurate identification of pseudofungi is required to avoid unnecessary treatment, and this can be accomplished by careful morp...

journal_title：International journal of surgical pathology

authors： Lyapichev KA,Agarwal AN,Rosenberg AE,Chapman JR

更新日期：2016-09-01 00:00:00

abstract：:Unlike their cutaneous counterparts, head and neck mucosal malignant melanomas (HNMM) behave much more aggressively and their prognostic markers have not been fully elucidated. Therefore, the aim of this study was to review the clinicopathologic features of a contemporary series of primary HNMM, retrieved from archiva...

journal_title：International journal of surgical pathology

authors： Kerr EH,Hameed O,Lewis JS Jr,Bartolucci AA,Wang D,Said-Al-Naief N

更新日期：2012-02-01 00:00:00

abstract：:Spitz tumors are a group of melanocytic neoplasms with distinct morphological features that tend to affect young individuals. Distinguishing benign from malignant Spitz tumors can be challenging, but cytogenetic and molecular tests have contributed to improvements in diagnostic accuracy. Spitz tumors harbor diverse ge...

journal_title：International journal of surgical pathology

authors： Kiuru M,Jungbluth A,Kutzner H,Wiesner T,Busam KJ

更新日期：2016-05-01 00:00:00

abstract：:PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...

journal_title：International journal of surgical pathology

authors： Ferenczi K,Lastra RR,Farkas T,Elenitsas R,Xu X,Roberts S,Brooks JS,Zhang PJ

更新日期：2012-02-01 00:00:00

abstract：:Mixed squamous and glandular papilloma (mixed papilloma) of the lung has been reported in fewer than 25 cases in the English literature. Although it is known as a benign tumor, malignant transformation has been reported. Papillary cystic carcinoma is characterized by papillary and cystic growth patterns and has been r...

journal_title：International journal of surgical pathology

authors： An AR,Park SY,Kim JH,Chae KJ,Chung MJ

更新日期：2020-09-01 00:00:00

abstract：:Malignant melanoma has a variety of morphologic patterns and can metastasize and mimic any type of neoplastic process creating significant diagnostic difficulty. When metastasis to the gastrointestinal system is identified, it is most commonly associated with widely metastatic disease. We report a rare case of isolate...

journal_title：International journal of surgical pathology

authors： Lo AA,Peevey J,Lo EC,Guitart J,Rao MS,Yang GY

更新日期：2015-08-01 00:00:00

abstract：:Tumor-to-tumor metastasis is an unusual phenomenon wherein one distinct malignancy is present within the substance of another independent tumor. This event is rare, difficult to detect with imaging, and, due to conflicting terminology in the literature, can be challenging to classify. This article reports the first do...

journal_title：International journal of surgical pathology

authors： Miller V,Hoellwarth JS,Hankins ML,McGough R,Schoedel K

更新日期：2020-04-01 00:00:00

abstract：:St. Gallen 2005 expert consensus guideline modified its criteria for the risk category of breast cancer (BC) patients by integrating a combination of lymph nodes with metastasis (positive lymph nodes [PLNs]) and HER-2/neu status of tumor. Recently, some studies have shown that lymph node ratio (LNR), defined as the ra...

journal_title：International journal of surgical pathology

authors： Yang C,Liu F,Li S,Li W,Zhai L,Ren M,Li Y,Lang R,Fan Y,Zhang X,Fu L

更新日期：2012-12-01 00:00:00

abstract：:Spontaneous regression of malignant tumour is a rare phenomenon. This report describes such an occurrence in a gastric large cell neuroendocrine carcinoma of a 77-year-old man. The patient presented with dyspepsia, and biopsy of the fungating mass in the cardia showed a high grade neuroendocrine carcinoma. The pre-ope...

journal_title：International journal of surgical pathology

authors： Ip YT,Pong WM,Kao SS,Chan JK

更新日期：2011-06-01 00:00:00

abstract：:Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in ...

journal_title：International journal of surgical pathology

authors： Suárez-Zamora DA,Barrera-Herrera LE,Rodríguez-Urrego PA,Palau-Lázaro MA

更新日期：2017-08-01 00:00:00

abstract：:We report a fourth case of papilliferous keratoameloblastoma, with a 6-year follow-up. A 62-year-old man underwent resection of a right mandibular neoplasm infiltrating bone and soft tissues. Microscopically, there were cysts lined by papillary projections and containing necrotic debris. Cribriform, solid, and tubular...

journal_title：International journal of surgical pathology

authors： Collini P,Zucchini N,Vessecchia G,Guzzo M

更新日期：2002-04-01 00:00:00

abstract：:Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...

journal_title：International journal of surgical pathology

authors： Ullah S,Ajab S,Rao R,Raghunathan G,DaCosta P

更新日期：2015-06-01 00:00:00

abstract：:In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects o...

journal_title：International journal of surgical pathology

authors： De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin D

更新日期：2014-05-01 00:00:00

abstract：:The authors describe the case of a 36-year-old man with gynecomastia who was previously treated with liposuction of the breast for cosmetic purposes. Histologic examination of a subsequent excisional biopsy revealed nests of displaced epithelial cells in adipose tissue. Epithelial cell displacement is a well-known ris...

journal_title：International journal of surgical pathology

authors： McLaughlin CS,Petrey C,Grant S,Ransdell JS,Reynolds C

更新日期：2011-08-01 00:00:00

abstract：:The aim of this study was to investigate protein expression of adenomatous polyposis coli (APC) in primary and metastatic serous ovarian carcinoma. The expression of beta-catenin and E-cadherin was additionally analyzed. One hundred and thirteen primary (n = 56) and metastatic (n = 57) lesions were immunohistochemical...

journal_title：International journal of surgical pathology

authors： Karbova E,Davidson B,Metodiev K,Tropé CG,Nesland JM

更新日期：2002-07-01 00:00:00

abstract：:We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...

journal_title：International journal of surgical pathology

authors： Li-Ning-T E,Ronchetti R,Torres-Cabala C,Merino MJ

更新日期：2005-10-01 00:00:00

abstract：:Mixed adenoneuroendocrine carcinomas (MANECs) of the biliary tract are rare tumors, and to date only a few cases arising in the gallbladder have been reported. Their histogenesis is a matter of debate, since the biliary tract normally lacks neuroendocrine cells. However, the immunohistochemical identification of nonne...

journal_title：International journal of surgical pathology

authors： Acosta AM,Hamedani FS,Kajdacsy-Balla A,Wiley EL

更新日期：2015-08-01 00:00:00