Tumor-to-Tumor Metastasis: Prostate Carcinoma Metastatic to Soft Tissue Sarcoma, a Previously Unreported Event.


:Tumor-to-tumor metastasis is an unusual phenomenon wherein one distinct malignancy is present within the substance of another independent tumor. This event is rare, difficult to detect with imaging, and, due to conflicting terminology in the literature, can be challenging to classify. This article reports the first documented case of tumor-to-tumor metastasis involving prostatic adenocarcinoma and myxoid liposarcoma, reviews the available literature for carcinoma metastatic to sarcoma, and discusses the current situation within the context of the established criteria for the classification of combination tumors.


Int J Surg Pathol


Miller V,Hoellwarth JS,Hankins ML,McGough R,Schoedel K




Has Abstract


2020-04-01 00:00:00












  • Metaplastic thymoma: report of an unusual thymic epithelial neoplasm arising in the wall of a thymic cyst.

    abstract::In this report, a case of metaplastic thymoma arising in a thymic cyst wall is discussed. The patient was a 61-year-old male whose chief complaint was sweating and chest pain. Imaging study revealed a mediastinal mass with right hemithoracic extension. He underwent surgical resection of the mass and remnants of the th...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Poorabdollah M,Mehdizadeh E,Mohammadi F,Sabeti S

    更新日期:2009-02-01 00:00:00

  • Loss of heterozygosity on chromosome 1 and 9 and hormone receptor analysis of metastatic malignant melanoma presenting in breast.

    abstract::Malignant melanoma (MM), the most common metastatic solid tumor to involve the breast, may present as a diagnostic problem, frequently requiring the use of ancillary studies for accurate diagnosis. The implication of hormonal interplay is strong since metastatic MM to the breast is seen nearly always in women. However...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Beaty MW,Quezado M,Sobel ME,Duray P,Merino MJ

    更新日期:2005-01-01 00:00:00

  • MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma.

    abstract::PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ferenczi K,Lastra RR,Farkas T,Elenitsas R,Xu X,Roberts S,Brooks JS,Zhang PJ

    更新日期:2012-02-01 00:00:00

  • Pseudofungi: A Diagnostic Pitfall.

    abstract::Pseudofungi are septate hyphae-like structures very similar morphologically to true fungal elements. Histologically their presence poses a diagnostic challenge as they mimic fungal infection. Accurate identification of pseudofungi is required to avoid unnecessary treatment, and this can be accomplished by careful morp...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lyapichev KA,Agarwal AN,Rosenberg AE,Chapman JR

    更新日期:2016-09-01 00:00:00

  • Superficial CD34-Positive Fibroblastic Tumor.

    abstract::Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Foot O,Hallin M,Bagué S,Jones RL,Thway K

    更新日期:2020-12-01 00:00:00

  • Diaphragm disease of the small intestine: an interesting case report.

    abstract::Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ullah S,Ajab S,Rao R,Raghunathan G,DaCosta P

    更新日期:2015-06-01 00:00:00

  • Comparison of biochemical recurrence-free survival between periprostatic and pelvic lymph node metastases of prostate cancer.

    abstract:OBJECTIVE:To assess the pathologic characteristics and prognostic significance of periprostatic lymph node (LN) metastasis of prostate cancer. The latter was performed by comparing biochemical recurrence (BCR)-free survival in cases of periprostatic LN metastasis versus matched patients showing pelvic LN metastasis. M...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: González-Roibón N,Han JS,Lee S,Feng Z,Arslankoz S,Smith N,Pierorazio PM,Humphreys E,Deweese TL,Partin AW,Bivalacqua TJ,Han M,Trock B,Netto GJ

    更新日期:2013-08-01 00:00:00

  • Podoplanin and E-cadherin expression in preoperative incisional biopsies of oral squamous cell carcinoma is related to lymph node metastases.

    abstract::Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Foschini MP,Leonardi E,Eusebi LH,Farnedi A,Poli T,Tarsitano A,Cocchi R,Marchetti C,Gentile L,Sesenna E,Marucci G,Montebugnoli L

    更新日期:2013-04-01 00:00:00

  • Histopathologic Spectrum of Neuromuscular and Vascular Hamartoma With Special Reference to the Vasculopathic Phenomenon.

    abstract::Neuromuscular and vascular hamartoma (NMVH) is an unusual lesion presenting as intestinal obstruction by stricture formation. It is characterized by a hamartomatous mass comprising haphazardly arranged mesenchymal tissue native to the intestinal mucosa and submucosa. We aimed to characterize the clinicohistopathologic...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ayyanar P,Purkait S,Mishra TS,Patra S,Mitra S

    更新日期:2020-06-01 00:00:00

  • Intralymphatic Histiocytosis of the Appendix and Fallopian Tube Associated With Primary Peritoneal High-Grade, Poorly Differentiated Adenocarcinoma of Müllerian Origin.

    abstract::Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Tran TAN,Tran Q,Carlson JA

    更新日期:2017-06-01 00:00:00

  • Isolated Gallbladder Intramucosal Metastatic Melanoma With Features Mimicking Lymphoepithelial Carcinoma.

    abstract::Malignant melanoma has a variety of morphologic patterns and can metastasize and mimic any type of neoplastic process creating significant diagnostic difficulty. When metastasis to the gastrointestinal system is identified, it is most commonly associated with widely metastatic disease. We report a rare case of isolate...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lo AA,Peevey J,Lo EC,Guitart J,Rao MS,Yang GY

    更新日期:2015-08-01 00:00:00

  • Rab11 is a useful tool for the diagnosis of microvillous inclusion disease.

    abstract::Microvillous inclusion disease (MVID) is a congenital condition presenting with intractable diarrhea. Biopsies demonstrate abnormal apical PAS and CD10 staining in surface enterocytes correlating with the presence of characteristic cytoplasmic inclusions. MVID has been linked to mutations in myosin Vb, important in ap...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Talmon G,Holzapfel M,DiMaio DJ,Muirhead D

    更新日期:2012-06-01 00:00:00

  • Palisaded Encapsulated (Solitary Circumscribed) Neuroma: A Review of 30 Cases.

    abstract::Background. Solitary circumscribed neuroma (SCN), also known as palisaded encapsulated neuroma (PEN), is a benign neural tumor. It may be mistaken as either schwannoma or neurofibroma in pathology practice. In this study, we aimed to define clinicopathologic and immunohistochemical features and discuss its differentia...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Leblebici C,Savli TC,Yeni B,Cin M,Aksu AEK

    更新日期:2019-08-01 00:00:00

  • Clinicopathologic Characteristics of Esophageal Ectopic Sebaceous Glands: Chronological Changes and Immunohistochemical Analysis.

    abstract::Esophageal ectopic sebaceous glands are very rare lesions. A series of 5 cases in a single report has been the maximum number described in the English literature to date. We conducted a clinicopathologic study of 8 cases of esophageal ectopic sebaceous glands. The median patient age at the time of diagnosis was 60 yea...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Hashimoto H,Horiuchi H,Miura S,Takayanagi S,Gunji T,Morikawa T

    更新日期:2020-08-26 00:00:00

  • Average Weight of Seminal Vesicles: An Adjustment Factor for Radical Prostatectomy Specimens Weighed With Seminal Vesicles.

    abstract::The International Society of Urological Pathology in 2010 recommended weighing prostates without seminal vesicles (SV) to include only prostate weight in prostate-specific antigen (PSA) density (PSAD) calculation, because SV do not produce PSA. Large retrospective cohorts exist with combined weight recorded that needs...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Tjionas GA,Epstein JI,Williamson SR,Diaz M,Menon M,Peabody JO,Gupta NS,Parekh DJ,Cote RJ,Jorda M,Kryvenko ON

    更新日期:2015-12-01 00:00:00

  • Composite Hemangioendothelioma With Neuroendocrine Marker Expression: Report of a "Paraganglioma-Like" Paravertebral Case.

    abstract::Composite hemangioendothelioma is a rare vascular tumor morphologically comprising several distinct vascular components and exhibits a borderline malignant potential. We described the case of a 53-year-old female who presented with an infiltrative mass in the paravertebral soft tissue. The tumor showed discrete nests ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Cheuk W,Shum KS,Ng WK,Chan JKC

    更新日期:2020-10-01 00:00:00

  • Lobular carcinoma in situ and infiltrating ductal carcinoma: frequent presence of DCIS as a precursor lesion.

    abstract::Infiltrating ductal carcinoma (IDC) occurs frequently in patients with lobular carcinoma in-situ (LCIS). LCIS is not thought to be the direct precursor of the invasive component. The authors analyzed 15 cases of coexisting LCIS and IDC and found ductal carcinoma in situ (DCIS) in 12. The DCIS and IDC were of similar g...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Maluf H,Koerner F

    更新日期:2001-04-01 00:00:00

  • Well-differentiated chondrosarcoma of the humerus with prominent granular cell component: a hitherto unreported occurrence.

    abstract::We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Cremonini A,Kuhn E,De Biase P,Franchi A

    更新日期:2006-04-01 00:00:00

  • Clear Cell Chondrosarcoma With Chondroblastoma-Like Features: A Case for Team Diagnosis.

    abstract::Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Kiefer RM,Wojcik J,Cooper K,Weber KL,Sebro R

    更新日期:2018-12-01 00:00:00

  • Lung adenocarcinoma metastasizing into a renal angiomyolipoma.

    abstract::Tumor-to-tumor metastasis is a very rare phenomenon. The most common donor and recipient of tumor-to-tumor metastasis are carcinomas of lung and renal cell carcinoma, respectively. We report a case of primary lung adenocarcinoma that metastasized into a renal angiomyolipoma 9 years after the resection of primary lung ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Wu PS,Pan CC

    更新日期:2015-05-01 00:00:00

  • Simple melanosis of the bladder: a rare entity.

    abstract::Simple melanosis of the bladder is an uncommon condition with fewer than 15 reported cases characterized by multifocal, diffuse melanin pigmentation of the urothelial mucosa. It is frequently associated with urinary incontinence or urgency. Histologically, melanin granules are present within urothelial cells or lamina...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Talmon GA,Khan AU,Koerber RK,Johansson SL

    更新日期:2010-12-01 00:00:00

  • Ductal adenocarcinoma of the pancreas with huge cystic degeneration: a lesion to be distinguished from pseudocyst and mucinous cystadenocarcinoma.

    abstract::Cystic neoplasms of the pancreas are rare and often mistaken for pseudocyst by imaging studies and macroscopic examination. We describe an unusual tumor of the pancreas composed of a mural nodule of anaplastic carcinoma arising from a huge ductal adenocarcinoma undergoing cystic degeneration. The cyst measured 27 x 13...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lee LY,Hsu HL,Chen HM,Hsueh C

    更新日期:2003-07-01 00:00:00

  • Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies.

    abstract::Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of l...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Jabbour MN,Tawil AN,Boulos FI

    更新日期:2016-04-01 00:00:00

  • Epithelioid Hemangioendothelioma of the Bowel in Crohn's Disease: The First Reported Case.

    abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Spasic S,Brcic I,Freire R,Garcia-Buitrago MT,Rosenberg AE

    更新日期:2019-06-01 00:00:00

  • Significance of IMP3, nucleophosmin, and Ki-67 expression in papillary thyroid carcinoma.

    abstract::The purpose of our study was to investigate the diagnostic value of expression of IMP3, nucleophosmin, and correlation of these markers with Ki-67 proliferation index in papillary thyroid carcinoma and benign neoplasms of thyroid gland. The aim was also to investigate whether there is a difference between papillary an...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Yorukoglu A,Yalcin N,Avci A,Cakalagaoglu F,Yaylali G,Akin F,Haciyanli M,Ozden A

    更新日期:2015-02-01 00:00:00

  • Primary Leiomyosarcoma of the Ovarian Vein: Case Report and Literature Review.

    abstract::Primary leiomyosarcoma arising from the ovarian vein is extremely rare, with only 10 cases reported in the literature. We report on a case of leiomyosarcoma of the left ovarian vein in a 67-year-old woman who presented with abdominal discomfort. Pelvic ultrasound revealed a large, solid, irregular mass in close relati...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审


    authors: López-Ruiz ME,Yébenes L,Berjón A,Hardisson D

    更新日期:2017-06-01 00:00:00

  • Uterine glomeruloid hemangioma in a patient without POEMS syndrome.

    abstract::Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Giner F,Compañ A,Monteagudo C

    更新日期:2012-08-01 00:00:00

  • A Note of Caution: Variable Cytokeratin Staining in Sentinel Node Metastases.

    abstract::Sentinel lymph node biopsy is the current standard procedure used to stage patients with breast cancer. The best histological method in evaluating sentinel nodes is highly debated among institutions and is thus not standardized. The optimal histological analysis is a balance between comprehensive evaluation of the sen...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Zeng J,Alexander MA,Nimeh D,Darvishian F

    更新日期:2015-10-01 00:00:00

  • Pulmonary hyalinizing granuloma associated with Aspergillus infection.

    abstract::A 38-year-old immunocompetent man with occupational exposure to Aspergillus presented with dyspnea, pleuritic chest pain, and hemoptysis. Chest roentgenograms and computed tomography scans demonstrated multiple pulmonary nodules bilaterally. An initial set of bronchial washing cultures grew Aspergillus fumigatus, sero...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Pinckard JK,Rosenbluth DB,Patel K,Dehner LP,Pfeifer JD

    更新日期:2003-01-01 00:00:00

  • Clinicopathologic Features of Benign Neurogenic Tumor of Urinary Bladder.

    abstract:BACKGROUND:Benign neurogenic tumor involving the urinary bladder is a very rare and heterogeneous disease group. The clinical and radiological diagnosis may be difficult because of the disease's rarity and the histological similarities of each disease especially in needle biopsy specimens. However, accurate diagnosis i...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lee C,Kim B,Song B,Park JH,Moon KC

    更新日期:2018-05-01 00:00:00