Tumor-to-Tumor Metastasis: Prostate Carcinoma Metastatic to Soft Tissue Sarcoma, a Previously Unreported Event.


:Tumor-to-tumor metastasis is an unusual phenomenon wherein one distinct malignancy is present within the substance of another independent tumor. This event is rare, difficult to detect with imaging, and, due to conflicting terminology in the literature, can be challenging to classify. This article reports the first documented case of tumor-to-tumor metastasis involving prostatic adenocarcinoma and myxoid liposarcoma, reviews the available literature for carcinoma metastatic to sarcoma, and discusses the current situation within the context of the established criteria for the classification of combination tumors.


Int J Surg Pathol


Miller V,Hoellwarth JS,Hankins ML,McGough R,Schoedel K




Has Abstract


2020-04-01 00:00:00












  • Acinar cell carcinoma with prominent intraductal growth pattern: case report and review of the literature.

    abstract::Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审


    authors: Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

    更新日期:2011-12-01 00:00:00

  • A Sclerosing Perineurioma With Collagen Rosette Formation: Benign Mimic of Low-Grade Fibromyxoid Sarcoma.

    abstract::We report the case of a sclerosing perineurioma with conspicious collagen rosette formation in a 20-year-old male presenting with a firm, painless nodule on the palmar side of his right ring finger. The main differential diagnosis is a low-grade fibromyxoid sarcoma. The distinction between these entities is important ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Creytens D,Ferdinande L,Van Dorpe J

    更新日期:2018-04-01 00:00:00

  • Mucinous and Signet Ring Cell Differentiation Affect Patterns of Metastasis in Colorectal Carcinoma and Influence Survival.

    abstract::Peritoneal metastasis in colorectal carcinoma is associated with a dismal prognosis; however, features that correlate with patterns of metastatic spread are not well characterized. We analyzed the clinicopathologic and molecular features of 166 patients with colorectal carcinomas stratified by metastases to the perito...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Kermanshahi TR,Magge D,Choudry H,Ramalingam L,Zhu B,Pingpank J,Ahrendt S,Holtzman M,Zeh H,Bartlett D,Zureikat A,Pai RK

    更新日期:2017-04-01 00:00:00

  • MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma.

    abstract::PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ferenczi K,Lastra RR,Farkas T,Elenitsas R,Xu X,Roberts S,Brooks JS,Zhang PJ

    更新日期:2012-02-01 00:00:00

  • Isolated tumor cells and circulating CK20 mRNA in pN0 colorectal cancer patients.

    abstract::Micrometastases in lymph nodes and blood may provide important prognostic information. In this study, cytokeratin 20 (CK20) positive cells in lymph nodes and circulating CK20 mRNA were studied using 57 paraffin-embedded lymph node specimens and blood from 24 patients with pN0 colorectal cancer (CRC), respectively. Res...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Wong CS,Cheung MT,Ma BB,Pun Hui E,Chan AC,Chan CK,Lee KC,Cheuk W,Lam MY,Wong MC,Chan CM,Chan JK,Chan AT

    更新日期:2008-04-01 00:00:00

  • Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst.

    abstract::A cystic swelling in the parotid gland should lead to a differential diagnosis that includes benign cystic lesion of the gland, benign tumors that are frequently associated with cystic degeneration or entirely cystic de novo, or even a malignant neoplasm. The case presented is that of a cystic parotid swelling of 2 ye...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Qannam A,Bello IO,Al-Kindi M,Al-Hindi M

    更新日期:2013-04-01 00:00:00

  • Clear Cell Chondrosarcoma With Chondroblastoma-Like Features: A Case for Team Diagnosis.

    abstract::Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Kiefer RM,Wojcik J,Cooper K,Weber KL,Sebro R

    更新日期:2018-12-01 00:00:00

  • Colorectal liver metastasis with intrabiliary growth: case report and review of the literature.

    abstract::Colorectal liver metastases with intrabiliary growth are uncommon and difficult to characterize by radiology alone. We present the case of a 61-year-old woman previously operated on for a left colon cancer who developed a metacronous lesion at liver segment II-III. Radiologic workup was indicative for cholangiocarcino...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审


    authors: Coppola S,Zucchini N,Romano F,Bovo G,Gilardoni E,Nespoli L,Gianotti L

    更新日期:2014-05-01 00:00:00

  • A Combined Deposition of Lanthanum and β2-Microglobulin-Related Amyloid in the Gastroduodenal Mucosa of Hemodialysis-Dependent Patients: An Immunohistochemical, Electron Microscopic, and Energy Dispersive X-Ray Spectrometric Analysis.

    abstract::Lanthanum carbonate (LC) is a new type of phosphate adsorbent used to treat patients with hyperphosphatemia caused by chronic kidney diseases. Recent studies have pointed out that lanthanum deposition can be found in the cytoplasm of histiocytes in the gastroduodenal mucosa of these patients. On the other hand, it is ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Komatsu-Fujii T,Onuma H,Miyaoka Y,Ishikawa N,Araki A,Ishikawa N,Yamamoto T,Mishiro T,Adachi K,Kinoshita Y,Tauchi-Nishi P,Maruyama R

    更新日期:2017-12-01 00:00:00

  • Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china.

    abstract::Goblet cell carcinoid (GCC) of the appendix is characterized by a dual differentiation of both endocrine and gland. This study, therefore, explores its clinicopathological and immunohistochemical features. The authors reviewed clinicopathological and immunohistochemical features of 26 GCC cases in Southwest China betw...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Yong Jiang,Huawei Liu,Hu Long,Yingying Yang,Dianying Liao,Xiuhui Zhang

    更新日期:2010-12-01 00:00:00

  • Primary Sellar Rhabdomyosarcoma Arising in Association With a Pituitary Adenoma.

    abstract::Intrasellar rhabdomyosarcoma is rare, and when arising in collusion with an unrelated entity, can present a diagnostic pitfall. We describe a case of a 56-year-old woman who presented with right eye ptosis and a pituitary mass, which was resected and diagnosed as atypical pituitary adenoma. Because of residual disease...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Duncan VE,Nabors LB,Warren PP,Conry RM,Willey CD,Perry A,Riley KO,Hackney JR

    更新日期:2016-12-01 00:00:00

  • Mid-Esophagus Columnar Metaplasia: What Is the Biopathogenic Pathway?

    abstract::We report a case of metaplastic columnar epithelium in the mid-esophagus in a patient with history of caustic ingestion. A cardiac-type gastric phenotype, with early signs of intestinalization, was confirmed by immunohistochemistry studies (MUC5AC, MUC6, SOX2, and CDX2). Nonmetaplastic mucosa had histologic evidence o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Rolim I,Rodrigues RV,Bettencourt A,Barros R,Camilo V,Dias Pereira A,Almeida R,Chaves P

    更新日期:2017-05-01 00:00:00

  • Head and neck mucosal malignant melanoma: clinicopathologic correlation with contemporary review of prognostic indicators.

    abstract::Unlike their cutaneous counterparts, head and neck mucosal malignant melanomas (HNMM) behave much more aggressively and their prognostic markers have not been fully elucidated. Therefore, the aim of this study was to review the clinicopathologic features of a contemporary series of primary HNMM, retrieved from archiva...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Kerr EH,Hameed O,Lewis JS Jr,Bartolucci AA,Wang D,Said-Al-Naief N

    更新日期:2012-02-01 00:00:00

  • Clinicopathologic Features of Benign Neurogenic Tumor of Urinary Bladder.

    abstract:BACKGROUND:Benign neurogenic tumor involving the urinary bladder is a very rare and heterogeneous disease group. The clinical and radiological diagnosis may be difficult because of the disease's rarity and the histological similarities of each disease especially in needle biopsy specimens. However, accurate diagnosis i...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lee C,Kim B,Song B,Park JH,Moon KC

    更新日期:2018-05-01 00:00:00

  • Acute Appendicitis and Pneumatosis in a Duplicated Appendix With Schistosoma Remnants.

    abstract::Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Handra-Luca A,Bisseret D,Dragoescu E

    更新日期:2016-02-01 00:00:00

  • Jaw cysts diagnosed in an Italian population over a 20-year period.

    abstract:BACKGROUND:Cysts of the jaws (JCs) are an important topic of oral pathology, but few epidemiological data are present in the literature, in particular about the potential of recurrence. The aim of this study was to describe a case series of JCs from a single institution, evaluating the frequency, the site, the age dist...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Del Corso G,Righi A,Bombardi M,Rossi B,Dallera V,Pelliccioni GA,Marchetti C,Foschini MP

    更新日期:2014-12-01 00:00:00

  • Metastasis of malignant peritoneal epithelioid mesothelioma in endoscopic gastric biopsy: a diagnostic pitfall.

    abstract:AIM:To describe a case of metastasis of malignant peritoneal epithelioid mesothelioma in gastric antral mucosa in a patient with a cryptogenic liver cirrhosis associated with esophageal varices, abdominal pain and distension, ascites, and weight loss. MATERIALS AND METHOD:The patient underwent esophageal gastric endos...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Daniele L,Righi A,Ferraris A,Macrì L,Asioli S

    更新日期:2011-04-01 00:00:00

  • Early colonic perineurioma: a report of 11 cases.

    abstract::Colonic perineurioma has been depicted as characterized by a mucosal proliferation of monomorphic spindle perineurial cells leading to an evident separation, distortion, and entrapment of colonic crypts. The authors, however, believe that a sizable subset of the cases differ in that they display only a limited perineu...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Groisman G,Amar M,Alona M

    更新日期:2010-08-01 00:00:00

  • Ductal adenocarcinoma of the pancreas with huge cystic degeneration: a lesion to be distinguished from pseudocyst and mucinous cystadenocarcinoma.

    abstract::Cystic neoplasms of the pancreas are rare and often mistaken for pseudocyst by imaging studies and macroscopic examination. We describe an unusual tumor of the pancreas composed of a mural nodule of anaplastic carcinoma arising from a huge ductal adenocarcinoma undergoing cystic degeneration. The cyst measured 27 x 13...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Lee LY,Hsu HL,Chen HM,Hsueh C

    更新日期:2003-07-01 00:00:00

  • Hepatic rosai-dorfman disease with coincidental lymphoma: report of a case.

    abstract::Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Di Tommaso L,Rahal D,Bossi P,Roncalli M

    更新日期:2010-12-01 00:00:00

  • Renal cell carcinoma in children and young adults: clinicopathological, immunohistochemical, and VHL gene analysis of 46 cases with follow-up.

    abstract::To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

    更新日期:2011-04-01 00:00:00

  • Podoplanin and E-cadherin expression in preoperative incisional biopsies of oral squamous cell carcinoma is related to lymph node metastases.

    abstract::Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Foschini MP,Leonardi E,Eusebi LH,Farnedi A,Poli T,Tarsitano A,Cocchi R,Marchetti C,Gentile L,Sesenna E,Marucci G,Montebugnoli L

    更新日期:2013-04-01 00:00:00

  • The Helpful Role of CD10 and Hormonal Receptors Co-Expression in the Histologic Diagnosis of Catamenial Pneumothorax.

    abstract::The histology in cases of primary spontaneous pneumothorax is generally nonspecific, but a careful examination, taking into account clinical data, may reveal subtle tissue alterations leading to a specific diagnosis in cases that might otherwise be taken as primary and spontaneous. In this article, we describe 3 cases...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Mataca E,Rossi G,Colby TV

    更新日期:2019-09-01 00:00:00

  • Clinicopathologic Characteristics of Esophageal Ectopic Sebaceous Glands: Chronological Changes and Immunohistochemical Analysis.

    abstract::Esophageal ectopic sebaceous glands are very rare lesions. A series of 5 cases in a single report has been the maximum number described in the English literature to date. We conducted a clinicopathologic study of 8 cases of esophageal ectopic sebaceous glands. The median patient age at the time of diagnosis was 60 yea...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Hashimoto H,Horiuchi H,Miura S,Takayanagi S,Gunji T,Morikawa T

    更新日期:2020-08-26 00:00:00

  • Spinal adrenal cortical adenoma with oncocytic features: report of the first intramedullary case and review of the literature.

    abstract::Ectopic adrenal cortical neoplasms are extremely rare, and only a few have involved the CNS. We report the first case of an intramedullary oncocytic adrenal cortical neoplasm of the spinal cord with immunohistochemical (IMHC) confirmation. A 27-year-old man presented with progressive lower extremity weakness, spastic ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Cassarino DS,Santi M,Arruda A,Patrocinio R,Tsokos M,Ghatak N,Quezado M

    更新日期:2004-07-01 00:00:00

  • Mucinous Variant of Follicular Carcinoma of the Thyroid Gland: Case Report and Review of the Literature.

    abstract::The rare reports of mucinous variant of follicular carcinoma of the thyroid gland have not provided enough evidence to support the recognition of these tumors as a distinct clinicopathologic entity or to understand their etiopathogenesis. We report the fourth case of mucinous variant of follicular carcinoma displaying...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审


    authors: Squillaci S,Pitino A,Spairani C,Ferrari M,Carlon E,Cosimi MF

    更新日期:2016-04-01 00:00:00

  • Diaphragm disease of the small intestine: an interesting case report.

    abstract::Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ullah S,Ajab S,Rao R,Raghunathan G,DaCosta P

    更新日期:2015-06-01 00:00:00

  • Malignant peripheral nerve sheath tumor with primitive neuroepithelial differentiation in an adult: a case report.

    abstract::Primitive neuroepithelial differentiation in malignant peripheral nerve sheath tumors (MPNSTs) has been reported in children but is extremely rare in adults. The authors report the case of a 70-year-old woman who presented with swelling of the right leg of 1-month duration. Fine-needle aspiration cytology was suggesti...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Anvikar AR,Kulkarni MP,Ramteerthakar NA,Gosavi AV,Sulhyan KR

    更新日期:2012-10-01 00:00:00

  • α-Fetoprotein-Producing Hepatoid Gastric Adenocarcinoma With Osteoclast-Like Giant Cells and Neuroendocrine Differentiation: A Case Study With Molecular Profiling.

    abstract::Here we present the case of a 73-year-old woman with an ulcerated, advanced, hepatoid, and α-fetoprotein-producing poorly differentiated (G3) primary gastric adenocarcinoma pT3 N3a M1 with multinucleated cells and evident neuroendocrine component. This tumor was consistent with giant cell tumor type gastric carcinoma ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Wincewicz A,Kowalik A,Zięba S,Lewitowicz P,Góźdź S,Sulkowski S

    更新日期:2015-10-01 00:00:00

  • Sinonasal rhabdomyosarcoma in children and young adults.

    abstract::Rhabdomyosarcoma is an aggressive malignant tumor often developing in the head and neck in children. In the sinonasal region, rhabdomyosarcoma constitutes a clinically important group because of the difficulty of surgical resection and its generally poor prognosis. We reviewed the archival pathology materials of 39 ca...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章


    authors: Ahmed AA,Tsokos M

    更新日期:2007-04-01 00:00:00